deborah e. keil - montana.edu · b.s., clinical laboratory science western carolina university, nc...
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Deborah E. Keil, PhD, MT(ASCP), DABT
Associate Professor
Department of Microbiology and Immunology
Medical Laboratory Sciences
Montana State University
Mailing @ 109 Lewis Hall
Research Laboratory 120 @ 960 Technology Park
Bozeman, Montana 59717
E-mail: [email protected]
EDUCATION
Ph.D., Biology (Immunotoxicology) Mississippi State University, MS 1996
B.S., Clinical Laboratory Science Western Carolina University, NC 1991
PROFESSIONAL EXPERIENCE
Associate Professor, Department of Microbiology and Immunology,
Montana State University, Bozeman, Montana 2012-current
Advisory Committee, Medical Laboratory Science Program, MSU 2013-current
Editorial Board, Journal of Toxicology and Environmental Health 2013-current
Professor (lecturer track), Medical Laboratory Sciences, Department of Pathology,
University of Utah, School of Medicine 2010-2012
Medical Laboratory Director, Southern Nevada Adult Mental Health Services (SNAMHS)
Rawson-Neal Psychiatric Hospital; Las Vegas, NV 2007-current
Appointed to Board of Directors, American Board of Toxicology (ABT) 2012-2016
Secretary, Executive Team 2014-2016
Subcommittees: Co-Chair Globalization Committee, ABT 2013-2014
Eligibility Committee, ABT 2012-2013
Chair Policy and Procedures Committee, ABT 2013-2014
Back-up Committee, ABT 2013
Electronic Testing Committee, Chair 2013
EPA Science Advisory Board (SAB) Trichloroethylene Health Assessment
Review Panel Member 2010
Associate Professor, Clinical Laboratory Science Program, School of Allied Health,
University of Nevada, Las Vegas 2005-2010
Research Toxicologist, Agriculture and Immunotoxicology Group, Office of the Director,
and Analytical Science Branch, Health Effects Laboratory Division,
National Institute for Occupational Safety and Health (NIOSH),
Centers for Disease Control 2002-2004
Associate Professor, Department of Medical Laboratory Sciences, MUSC 2000-2002
Assistant Professor, Department Medical Laboratory Sciences, MUSC 1996-2000
Adjunct Faculty, Marine Biomedical Environmental Science Program, MUSC 1999-2002
U.S. Army Summer Faculty Research & Engineering Program. Walter Reed Army
Institute of Research, Washington, D.C. Mentor: Dr. Urszula Kryzch. 1997
Medical Technologist, Oktibbeha County Hospital, Starkville, MS 1991-1996
Medical Technologist, Mission Memorial Hospital, Asheville, NC 1991
CERTIFICATIONS and LICENCES and PROFESSIONAL MEMBERSHIPS
Society of Toxicology, Associate Member 1991-current
American Society for Clinical Laboratory Science (ASCLS) 2005-current
American Association for Bioanalysts (AAB) 2013-current
Medical Technology, Association of the Society of Clinical Pathologists (MT#188480) 1991-current
Keil; July 2016; Page 2 of 24
Diplomate of the American Board of Toxicology (DABT) 2006-current
Recertification: Diplomate of the American Board of Toxicology (DABT) 2010, 2015
Board of Directors, American Board of Toxicology 2011-2015
Licensed Laboratory Director, State of Nevada (#19830DIR-4) 2007-current
FELLOWSHIPS and HONORS
Developing Scholar of the Year Award, Health Sciences Foundation, MUSC 2000
Scholar of the Year Award, College of Health Professions, MUSC 1999
Outstanding Presentation in Risk Assessment, Society of Toxicology, Baltimore, MD. 1995
Department of Biological Sciences, MSU, Graduate Research Fellowship 1994
Outstanding Presentation, Immunology and Microbiology Division of the
Mississippi Academy of Science 1992
PUBLICATIONS
Peer-Reviewed
1. DeWitt, J., Buck, B., Goossens,D., Teng, Y., Pollard, J., McLaurin, B., Gerads, R. and Keil, D.E. 2016.
Toxicity of Geogenic Dust Exposure from the Drainage Surfaces of the Nellis Dunes Recreation
Area, Las Vegas, NV. To be submitted Toxicology Reports
2. Keil, D.E., Buck, B., Goossens, D., Pollard, J., McLaurin, B., Gerads, R., and DeWitt, J. 2016. Health
Effects Due to Atmospheric Mineral Dust Near Las Vegas, NV. Submitted Toxicology Reports
3. DeWitt, J., Buck, B., Goossens, D., Hu, Q., Boles, C., Chow, R., David, W, Young, S., Teng, Y.,
Spencer, M., Murphy, L., Pollard, J., McLaurin, B., Gerards, R., and Keil, D.E. 2016. Health effects
following subacute exposure to geogenic dusts from arsenic-rich sediment at the Nellis Dunes
Recreation Area, Las Vegas, NV. Accepted Toxicology and Applied Pharmacology. Impact Factor 2014
= 3.705; 5yr: 4.069
4. Leetham, M., DeWitt, J., Buck, B., Goossens, D., Teng, Y., Pollard, J., McLaurin, B., Gerads, R., and
Keil, D.E. 2016. Oxidative stress and lung pathology following geogenic dust exposure. Accepted Dec
15, 2015 Journal of Applied Toxicology, Feb 29. doi: 10.1002/jat.3297. [Epub ahead of print] PMID:
26922875. Impact Factor 2015 = 2.98
5. Keil, D.E., Buck, B., Goossens, D., Leetham, M., Murphy, L., Eggers, M., Pollard, J., McLaurin, B.,
Gerads, R., and DeWitt, J. 2015. Immunotoxicological and Neurotoxicological Profile of Health Effects
Following Subacute Exposure to Geogenic Dust from Sand Dunes of the Nellis Dunes Recreation Area,
Las Vegas, NV. Toxicology and Applied Pharmacology Vol 291, January 2016, p.1-12.
doi:10.1016/j.taap.2015.11.020. PMID: 26644169. Impact Factor 2014 = 3.705; 5yr: 4.069
6. DeWitt, J. C., Peden-Adams, M. M., Keil, D.E., & Anderson, S. E. 2012. PPAR involvement in PFAA
immunotoxicity. Reproductive Toxicology, 33(4), 596-597
7. Keil, D.E., and Arlitsch, K. 2012. Scientists and Librarians Create an Environmental Toxicology
Repository. Science and the Internet. Editors Alexander Tokar, Michael Beurskens, Susanne Keuneke,
Merja Mahrt, Isabella Peters, Cornelius Puschmann, Timo van Treeck, Katrin Wellerp. Dusseldorf
University Press. Page 145. ISBN 978-3-943460-16-2. http://www.uni-
duesseldorf.de/home/fileadmin/redaktion/DUP/PDF-Dateien_/Open_Access/Science_and_the_Internet_OA.pdf
8. Fair, P., Driscoll, E., Mollenhauer, M.A.M., Bradshaw, S., Yun, S., Kannan, K., Bossart, G.D., Keil,
D.E., and Peden-Adams, M.M. 2011. Effects of environmentally relevant levels of perfluorooctone
Keil; July 2016; Page 3 of 24
sulfonate on clinical parameters and immunological functions in B6C3F1 mice. Journal of
Immunotoxicology, Jan-Mar;8(1):17-29. doi: 10.3109/1547691X.2010.527868. Impact Factor 2010:
1.955 PMID: 21261439
9. Fair, P., Stavros, H.C., Mollenhauer, M., DeWitt, J.C., Henry, N., Kannan, K., Mitchum, G., Yun, S.H.
Bossart, G., Keil, D.E., Peden-Adams, M.M. 2011. Immune function is modulated by DE-71 in Female
B6C3F1 Mice. (2012) Journal of Immunotoxicology, 40:230-236. PMID: 22214215. Impact Factor
2010: 1.955
10. DeWitt, J., Peden-Adams, M.M., Keil, D.E., and Deitert, R. 2011. Current Status of Developmental
Immunotoxicity: Early Life Patterns and Testing. Toxicologic Pathology, 40-230-236. PMID:22109713
Impact Factor 2010: 2.168;
11. Keil, D.E., Berger-Ritchie, J., McMillin, G. Testing for toxic elements; a focus on arsenic, cadmium,
lead and mercury (10-12-LM-S-CE-0187). 2011. LabMedicine. Impact Factor 2010: 0.267
12. Klaassen, J and Keil, D.E. 2010. Discouraging Academic Dishonesty in Online Courses. Accepted to
Clinical Laboratory Science Journal, Special Education Edition, Vol 23, No 4, Fall 2010. p194-200.
PMID: 21140791
13. Peden-Adams, M.M., Stuckey, J.E., Gaworecki, K., Berger-
T., Boone, J.S., Ferrario, J.B., Guan, B., Vigo, C., McGuinn, W.C., DeWitt, J.C., and Keil, D.E. 2009.
Developmental toxicity of perfluorooctane sulfonate (PFOS) in white leghorn chickens following in ovo
exposure. Reproductive Toxicology, 27:307-318. Impact Factor: 2.957
14. Keil, D.E., Dudley, A.C., EuDaly, J., Allen, C.T., Gilkeson, G.S., and Peden-Adams, M.M. 2009. N,N,-
diethyl-m-toluamide (DEET) alters immune function in B6C3F1 mice. Toxicological Sciences, 108:110-
123. Impact factor 2010: 5.093
15. Peden-Adams, M.M., Keil, D.E., and Gilkeson, G.S. 2008. Response to “Comments on ‘Lifetime
exposure to trichloroethylene (TCE) does not accelerate autoimmune disease in MRL+/+ mice”’ Letter
to the Editor. Journal of Environmental Science and Health, Part A, 43:1402-1409. Impact Factor:
1.992
16. Keil, D.E., Peden-Adams, M.M., Wallace, S. Redmond, K., Ruiz, P., and Gilkeson, G.S. 2008.
Assessment of trichloroethylene (TCE) exposure in murine strains genetically-prone and non-prone to
develop autoimmune disease. Journal of Environmental Science and Health, Part A, 2009, 44:443-453;
Impact Factor: 1.992
17. Peden-Adams, M.M., EuDaly, J.G., Miller, J., Keil, D.E. and Gilkeson, G.S. 2008. Lifetime exposure to
trichloroethylene does not accelerate autoimmune disease in MRL +/+ mice. Journal of Environmental
Science and Health, Part A, 43:1402–1409; Impact Factor: 1.992
18. Peden-Adams, M.M., Keller, J.M., EuDaly, J.G., Berger, J., Gilkeson, G.S., and Keil, D.E. 2008.
Suppression of humoral immunity following exposure to perfluorooctane sulfonate (PFOS).
Toxicological Sciences, 104:144-154; Impact factor 2010: 5.093
19. Keil, D.E., Mehlmann, T., Butterworth, L. and Peden-Adams, M.M. 2008. Gestational Exposure to
PFOS Suppresses Immunological Function in F1 Mice. Toxicological Sciences, 103:77-85; Impact
factor 2010: 5.093
20. Cheney, M.A., Keil, D.E. and Qian, S. 2008. Uptake and Effect of Mercury on Amino Acid Losses
from the Gills of the Bivalve Mollusks Mytilus californianus and Anodonta californirnsis. Journal of
Colloid and Interface Science, 320:369-375. 5 Yr Impact Factor: 2.755
Keil; July 2016; Page 4 of 24
21. Peden-Adams, M.M., EuDaly, J.G., Dabra, S., EuDaly, A., Heesemann, L. M., Smythe, J., and Keil, D.E.
2007. Suppression of humoral immunity following exposure to the perfluorinated insecticide
sulfluramid. Journal of Environmental Science and Health, Part A, 70(13):1130-1141; Impact Factor:
1.992.
22. Peden-Adams, M.M., EuDaly, J.G., Heesemann, L. M., Smythe, J., Miller, J., Gilkeson, G.S., and Keil,
D.E. 2006. Developmental immunotoxicity of trichloroethylene (TCE): Studies in B6C3F1 mice.
Journal of Environmental Science and Health, Part A, 41:249-271; Impact Factor: 1.992
23. Leonard, S.S., Keil, D.E., Mehlmann, T., Proper, S., Xianglin, S., and Harris, G.K. 2006. Essiac tea:
Scavenging of reactive oxygen species and effects on DNA damage. Journal of
Ethnopharmacology, 103(2):288-96; Impact Factor: 2.049
24. Keller, J.M., McClellan-Green, P.D., Kucklick, J.R., Keil, D.E., and Peden-Adams, M.M. 2006. Effects
of organochlorine contaminants on loggerhead sea turtle immunity: Comparison of a correlative field
study and in vitro exposure experiments. Environmental Health Perspectives, 114(1): 70-76; Impact
Factor: 5.86
25. B’Hymer, C., Keil, D.E., and Cheever, K.L. 2005. A Test Procedure for the Determination of the (2-
Methoxyethoxy) acetic Acid in Urine from Jet Fuel Exposed Mice. Toxicology Mechanisms and
Methods, 15 (5): 367; Impact Factor: 0.557
26. Keller, J.M., McClellan-Green, P.D., Lee, A.M., Arendt, M.D., Maier, P.P., Segars, A.L., Whitaker,
J.D., Keil, D.E., and Peden-Adams, M.M. 2005. Mitogen-Induced Lymphocyte Proliferation of
Loggerhead Sea Turtles: Comparison of Methods and Effects of Gender and Body Condition on
Immunity. Veterinary Immunology and Immunopathology, Feb 10;103(3-4):269-81; Impact Factor:
1.652
27. Peden-Adams, M.M., Dudley, A.C., EuDaly, J.G., Allen, C.T., Gilkeson, G.S., and Keil, D.E. 2004.
Pyridostigmine bromide alters immune function in B6C3F1 mice. Immunopharmacology and
Immunotoxicology 26(1)1-15; Impact Factor: 0.766
28. Keil, D.E., Dudley, A.C., EuDaly, J., Dempsey, J., Butterworth, L., Gilkeson, G.S., and M.M. Peden-
Adams. 2004. Immunological and hematological effects observed in B6C3F1 mice exposed to JP-8 jet
fuel for 14 days. Journal of Toxicology and Environmental Health, Part A, 67:1-21; 5 Yr Impact
Factor: 1.992
29. Komutarin, T., Azadia, S., Butterworth, L., Keil, D., Chitsomboon, B., Suttajit, M., and Meade,
B.J. 2004. Extract of the seed coat of Tamarindus indica inhibits nitric oxide production by
murine macrophages in vitro and in vivo. Food and Chemical Toxicology, 42(4):649-58;
Impact Factor: 2.186
30. Swenk, R., Asher, L., Chalom, I., Lanar, D., Sun, P., White, K., Keil, D., Kester, K., Stoute, J.,
Gray Heppner, D., and Krzych, U. 2003. Opsonization by antigen-specific antibodies a
mechanism of protective immunity induced by Plasmodium falciparum circumsporozoite
protein-based vaccine. Parasite Immunology, 25:17-25; Impact Factor: 2.231
31. Keil, D.E., Warren, D.A., Jenny, M.J., EuDaly, J., Smythe, J., and M.M. Peden-Adams. 2003.
Immunological function in mice exposed to JP-8 jet fuel in utero. Toxicological Sciences,
76(2):347-356; Impact factor 2010: 5.093
Keil; July 2016; Page 5 of 24
32. Allen, C.T., Peden-Adams, M.M, EuDaly, J., and Keil, D.E. 2003. Subchronic exposure to ellagic acid
impairs cytotoxic T-cell function and suppresses humoral immunity in mice. Immunopharmacology and
Immunotoxicology, 25 (3): 409-422; Impact Factor: 0.766
33. Watt, J.M., Wade, M.M., Holman, S.C., Wilson, W.W., Keil, D.E., Pruett, S.B., Jacques, M., Champlin,
F.R. 2003. Influence of serotype A capsulation on cell surface physiologic factors in Pasteurella
multocida. Colloids and Surfaces B: Biointerfaces. 28:227-238. Impact Factor: 2.562
34. Peden-Adams M.M., EuDaly, J., EuDaly, E., Dudley, A., Zeigler, J., Lee, A., Robbs, J., Gilkeson, G. and
Keil, D.E. 2002. Evaluation of immunotoxicity induced by single or concurrent exposure to N,N-
diethyl-m-toluamide, pyridostigmine bromide and JP-8 jet fuel. Toxicology and Industrial Health, 17(5-
10): 192-209; Impact Factor: 0.731
35. Wear, D.J., D.E. Keil, and R. Altig. 2002. Interobserver survey comparisons: Stream frogs in
southeastern Madagascar and a lab test. Herpetological. Natural History 9(1): 79-82. Impact Factor:
0.76
36. Keil, D.E., Leubke, R.W., and Pruett, S.B. 2001. Quantifying the relationship between immunological
parameters and host resistance. Journal of Immunology, 167:4543-4552; Impact Factor: 7.145.
37. Pruett S.B., Myers, L.P., and Keil D.E. 2001. Toxicology of metam sodium. Journal of Toxicology &
Environmental Health. Part B, Critical Reviews. 4(2):207-22. 5 Yr Impact Factor: 4.341
38. Dudley, A.C., Peden-Adams, M., EuDaly, J., Pollenz, R.S., and Keil, D.E. 2001. An aryl hydrocarbon
receptor independent mechanism of immunotoxicity of JP-8 jet fuel. Toxicological Sciences, 59: 251-
259; Impact factor 2010: 5.093
39. Keil, D.E., Luebke, R.W., Ensley, M., Gerard, P., and Pruett, S.B. 1999. Evaluation of multivariate
statistical methods for analysis and modeling of immunotoxicology data. Toxicological Sciences,
51:245-258; Impact factor 2010: 5.093
40. Keil, D.E., Padgett, E.L., Barnes, D.B., and Pruett, S.B. 1996. The role of decomposition products in
sodium dimethyldithiocarbamate (SMD)-induced immunotoxicity. Journal of Toxicology and
Environmental Health, Part A, 47:479-492. 5 Yr Impact Factor: 1.992
41. Moore, C., Keil, D.E, and Coats, K. 1996. Thermal Inactivation of Bovine Immunodeficiency Virus.
Applied and Environmental Microbiology, 62:4280-4283
42. Keil, D.E., Luebke, R.W., and Pruett, S.B. 1995. Differences in the effects of dexamethasone on
macrophage nitrite production: Dependence on exposure regimen (in vivo or in vitro) and activation
stimuli. International Journal of Immunopharmacology, 17:157
43. Pruett, S. B., Ensley, D.K. and Crittenden, P. 1993. (formerly D.K. Ensley). The role of chemical-
induced stress responses in immunosuppression: A review of quantitative associations and cause-effect
relationships between chemical-induced stress responses and immunosuppression. Journal of
Toxicology and Environmental Health, Part A, 39:163. 5 Yr Impact Factor: 1.992
Published Educational Reviews
Keil, D.E. 1999. Bacterial sepsis associated with platelet transfusion. American Society of Clinical
Pathologists. Tech Sample No. I-4. p. 21-26
Keil; July 2016; Page 6 of 24
Keil, D.E. 1998. Serologic problems associated with intravenous immunoglobulin therapy. American
Society of Clinical Pathologists. Tech Sample No. I-4. p. 23-28
BOOK and FINAL REPORT CHAPTERS
DeWitt, J.C. and Keil, D.E. 2015. Chapter: Current Issues in Developmental Toxicology in
Immunopathology in Toxicology and Drug Development. September 15, 2015 Submission and
Completion.
Keil, D.E. 2014. Immunotoxicity of PFOS and PFOA. Chapter in: Toxicity of Perfluoroalkyl and
Polyfluoroalkyl Substances. Editor: J. DeWitt. Springer Publishers, UK. Chapter Completed May,
2014. Page 239-248. http://link.springer.com/chapter/10.1007%2F978-3-319-15518-0_10
DeWitt, J. C., Peden-Adams, M. M., & Keil, D.E. 2014. Immunotoxic Effects of Perfluoroalkylated
Compounds: Mechanisms of Action. Edited by Emanuela Corsini and Henk Van Loveren. Published
by John Wiley and Sons. Molecular Immunotoxicology, 2007, 1. Print ISBN: 978-3-527-33519-0;
ePub ISBN: 978-3-527-67699-6
Keil, Deborah; DeWitt, Jamie; Spencer, Mallory; Murphy, Lacey; David, Winnie; Chow, Rebecca;
Young, Sharon; Hu, Qing; Eggers, Margaret; Gerads, Russ; Goossens, Dirk; Buck, Brenda. 2014.
Immunotoxicological and Neurotoxicological Effects of Subacute Exposure to CBN 1 Dust Samples,
In Nellis Dunes Recreational Area: Dust Exposure and Human Health Risk Assessment, Final Report
to Bureau of Land Management for Task Agreement Number L11AC20058, p. 233 – 276.
Keil, Deborah; DeWitt, Jamie; Hu, Qing; Chow, Rebecca; David, Winnie; Young, Sharon; Spencer,
Mallory; Murphy, Lacey; Teng, Yuanxin; Goossens, Dirk; Buck, Brenda. 2014. Immunotoxicological
and Neurotoxicological Effects of Subacute Exposure to CBN 2 Dust Samples, In Nellis Dunes
Recreational Area: Dust Exposure and Human Health Risk Assessment, Final Report to Bureau of
Land Management for Task Agreement Number L11AC20058, p. 277 – 294.
DeWitt, Jamie; Keil, Deborah; Hu, Qing; David, Winnie; Spencer, Mallory; Murphy, Lacey; Eggers,
Margaret; Goossens, Dirk; Buck, Brenda. 2014. Immunotoxicological and Neurotoxicological Effects
of Subacute Exposure to CBN 3 Dust Samples, In Nellis Dunes Recreational Area: Dust Exposure and
Human Health Risk Assessment, Final Report to Bureau of Land Management for Task Agreement
Number L11AC20058, p. 295 – 309.
DeWitt, Jamie; Keil, Deborah; Hu, Qing; David, Winnie; Spencer, Mallory; Murphy, Lacey; Eggers,
Margaret; Goossens, Dirk; Buck, Brenda. 2014. Immunotoxicological and Neurotoxicological Effects
of Subacute Exposure to CBN 4 Dust Samples, In Nellis Dunes Recreational Area: Dust Exposure and
Human Health Risk Assessment, Final Report to Bureau of Land Management for Task Agreement
Number L11AC20058, p. 310 – 326.
Keil, Deborah; DeWitt, Jamie; Spencer, Mallory; Murphy, Lacey; Goossens, Dirk; Teng, Yuanxin;
Buck, Brenda. 2014. Immunotoxicological and Neurotoxicological Effects of Subacute Exposure to
CBN 5 Dust Samples, In Nellis Dunes Recreational Area: Dust Exposure and Human Health Risk
Assessment, Final Report to Bureau of Land Management for Task Agreement Number L11AC20058,
p. 328 – 342.
Keil, Deborah; Dewitt, Jamie; Goossens, Dirk; Hu, Qing; Spencer, Mallory; Murphy, Lacey; David,
Winnie; Eggers, Margaret; Chow, Rebecca; Young, Sharon; Teng, Yuanxin; Buck, Brenda. 2014.
Immunotoxicological and Neurotoxicological Effects of Subacute Exposure to CBN 6 Dust Samples,
In Nellis Dunes Recreational Area: Dust Exposure and Human Health Risk Assessment, Final Report
to Bureau of Land Management for Task Agreement Number L11AC20058, p. 343 – 358.
Keil; July 2016; Page 7 of 24
DeWitt, Jamie; Keil, Deborah; Hu, Qing; David, Winnie; Spencer, Mallory; Murphy, Lacey; Eggers,
Margaret; Goossens, Dirk; Buck, Brenda. 2014. Immunotoxicological and Neurotoxicological Effects
of Subacute Exposure to CBN 7 Dust Samples, In Nellis Dunes Recreational Area: Dust Exposure and
Human Health Risk Assessment, Final Report to Bureau of Land Management for Task Agreement
Number L11AC20058, p. 359 – 376.
Spencer, Mallory; Keil, Deborah; DeWitt, Jamie. 2014. Oxidative Stress and Lung Histopathology
Following Sub-Acute Exposure to Natural Dust Collected From The Nellis Dunes Recreational Area,
In Nellis Dunes Recreational Area: Dust Exposure and Human Health Risk Assessment, Final Report
to Bureau of Land Management for Task Agreement Number L11AC20058, p. 434 – 454.
Keil, D.E. 2013. Protein Chapter for Clinical Chemistry: Techniques, Principles, Correlations 7th
edition, 2013. Editors: Bishop, Fody, and Schoeff. Lippincott Publishers. ISBN 978-1-4511-1869-8
Keil, D.E. 2013. Toxicology Chapter for Clinical Chemistry: Techniques, Principles, Correlations 7th
edition for 2013. Editors: Bishop, Fody, and Schoeff. Lippincott Publishers. ISBN 978-1-4511-
1869-8
Keil, D.E. and Ayala, N. 2013. Therapeutic Drug Monitoring Chapter for Clinical Chemistry:
Techniques, Principles, Correlations 7th edition, 2013. Editors: Bishop, Fody, and Schoeff.
Lippincott Publishers. ISBN 978-1-4511-1869-8
McMillan, G.A., Keil, D.E., Strathmann, F.G. 2012. Chapter 21: Lead Testing in The Clinical
Toxicology Laboratory – Contemporary Practice of Poison Evaluation, 2nd edition. Published by
AACC Press. Editors, T. Kwong, B. Magnani, T. Rosano, P. Orsulak, and L. Shaw.
DeWitt, J.C., Peden-Adams, M.M., Keil, D.E., and Dietert, R.R. 2012. Developmental
Immunotoxicity (DIT): assays for evaluating effects of exogenous agents on development of the
immune system. In: Current Protocols in Toxicology. Chapter 18: Unit 18.15. PMID: 22511116
Keil, D.E. 2006. Immunotoxicology of Jet Propulsion Fuel-8. Chapter in 3rd edition,
Immunotoxicology and Immunopharmacology. Editor Dr. Robert Leubke, EPA. CRC Press.
Pruett, S.B. and Keil, D.E. 1999. Metam Sodium. Invited chapter in Hayes Handbook of Pesticide
Toxicology, Academic Press, San Diego.
Wu, W. J., Carson, E. J., Collier, S. D., Keil, D.E., Weiss, P. A., and Pruett, S. B. 1996. Effects of
drugs on immune system parameters. Handbook of Human Toxicology. Edited by Dr. E. J. Massaro.
CRC Press, Inc., Boca Raton, Fl.
Pruett, S.B., Keil, D.E., Ensley, M., and Luebke, R.W. 1996. Interspecies immunotoxicity: Relative
importance of acquired and innate immune functions. Modulators of Immune Responses. The
Evolutionary Trail. Eds. J.S. Stolen, T.C. Fletcher, C.J. Secombes, J.T. Zelikoff, L.E. Twerdok, D.P.
Anderson. SOS Publications, Fair Haven, NJ. p. 343-350
GRANTS FUNDED
R13 NIEHS Conference Grant. “Elongate Mineral Fiber Terminology and Characterization” and
“Novel Research Findings on Environmental Asbestos Exposure”. PI: Jean Pfau and Deborah
Keil. $50,000. Submitted Dec 11, 2015.
Emerging Exposures to Natural Occurring Asbestos in Western States: Fiber Specific
Pulmonary and Autoimmune Health Effects in a Mouse Model. $50,000. PIs: Deborah E. Keil
Keil; July 2016; Page 8 of 24
and Jean C. Pfau. MAES, College of Agriculture, Montana State University. Funded October 2015-
July 2016.
University of New Mexico Center for Native Environmental Health Equity Research. NIH/EPA.
1P50ES026102. Center PI Lewis/Gonzales; Total Award: $5,000,000. MSU PI: Keil, Total SubAward:
$530K. 07/01/2015-06/30/2020. Addressing environmental health (EH) disparities and social
determinants with primary biomedical and environmental research and Native-focused community
engagement is the goal of the Center for Native American Environmental Health Equity Research.
Status: Funded through 2020.
Chronic Exposure to Contaminants in Drinking Wells on the Crow Reservation:
Characterization of Health Effects and Strategies for Intervention. P20GM103474. PI: Deborah
E. Keil. Co-PI: John Doyle. 3/26/2015-04/30/2015. $50,000. This proposal was developed with
community partners of the Crow Steering Committee and community in Little Big Horn, Montana.
Status: Funded for 2015; Data analysis with INBRE statisticians ongoing through Nov 2015.
Safety through Simulation: Interdisciplinary Educational Activities to Enhance Teamwork
between Nursing and Medical Laboratory Students. Jan 7, 2013 – December 2013. $8,900.
Principal Investigators: Elizabeth Kinion, Deborah E. Keil, Teresa Seright, Barbara Hudson. Funded
by MSU Innovation in Teaching,. Status: Funded for 2013
Human Health Risk Assessment of Nellis Dunes Recreational Area. Submitted to Bureau of Land
Management. April 2011 – September 2014. $2,500,000. Principal Investigators: Brenda Buck (UNLV),
Deborah E. Keil (UU/UNLV), Dirk Goosens (UNLV), Jamie DeWitt (ECU), Margie Peden-Adams
(UNLV/NOAA). Status: Completed. Task Agreement: L11AC20058. Sub award to MSU
approximately $375K.
Immunotoxicological Assessment of Dust Samples Collected From the Nellis Air Force Base: A
Pilot Study. Spring 2010. $10,000. Subcontract with Bureau of Land Management and PI Brenda
Buck, Ph.D. Principal Investigator for subcontract: Deborah E. Keil; Co-PI: Margie Peden-Adams
Plasma Ghrelin Levels Following Diet-Induced Weight Loss. December 2008. $10,000.
Foundation Grant. Funding Period: 1 year. Principal Investigators: Sally Miller (nursing); Co-PI:
Deborah E. Keil
Plasma Ghrelin Levels Following Diet-Induced Weight Loss. September 2008. $10,000. UNLV
RDA. Funding Period: 1 year. Principal Investigators: Sally Miller (nursing); Co-PI: Deborah E. Keil
Labs are Vital, Abbott Laboratory. AxSYM Clinical Chemistry Instrumentation. September
2008. $127,000. Principal Investigators: Janice Conway-Klaassen and Deborah E. Keil
Establishment of a Clinical Research Core Laboratory. Awarded December 2007. University of
Nevada Las Vegas, Research Infrastructure Award. Total: $100,000. Funding Period: 1 year. Principal
Investigators: Deborah E. Keil, J. Klaassen, J. McWhorter, M. Landers, M. Elekonich, M. Peden-
Adams
Development of Carbon Nanotube Pipettes (CNPs) for Single Cell Surgery in Nanomedicine Era.
Awarded August 2007. University of Nevada Las Vegas, Presidents Award. Total: $50,000. Funding
Period: 2 years. Investigators: Shizhi Qian, Yingtao Jiang, Biswajit Das, Marcos A. Cheney, Deborah
E. Keil.
Establishing Biomarkers for Low Back Pain Disability. Funded by University of Nevada Las
Vegas. Awarded May 1, 2007. Total: $9,541. Funding Period: 1 year. Principal Investigators: Nancy
Mendel, Merrill Landers, and Deborah E. Keil.
Keil; July 2016; Page 9 of 24
The Role of PFOS on Immunological Cell Types and Mechanisms of Suppression in the
Development of Primary IgM Immunological Responses. Funded by School of Health and Human
Sciences, University of Nevada Las Vegas. Awarded February 2006. Total: $6,666. Funding Period:
1 year. Principal Investigator: Deborah E. Keil; Co-Investigator: Margie Peden-Adams, Ph.D. In
addition, EPSCOR Nevada also funded an undergraduate student, Ms. Jennifer Berger, in support of this
project for an additional $4,500.
A Comparative Study Evaluating the Dose-Responsive Effects of Methylmercury and Thimerosal
on Select Nervous, Immune and Enzyme Parameters during Vulnerable Periods of Development.
Funded by Cure Autism Now Foundation. Awarded August 1, 2001. Total: $171,756. Funding Period:
Mar 2002-Mar 2004. Principal Investigator: Deborah E. Keil, Ph.D., Co-Investigators: Margie Peden-
Adams, Ph.D. and Ronald Brown, Ph.D.
Evaluation of Immunotoxicity Due to Concurrent Exposure to DEET, Pyridostigmine, and JP-8
Jet Fuel. Funded by the Department of Army. US Army Center for Environmental Health Research.
Total: $448,369. Funding Period: February 1999 – February 2002. Principal Investigator: Deborah E.
Keil, Ph.D. Co-Investigator: Gary Gilkeson, MD.
Immunotoxicity Due to Coexposure of DEET, Pyridostigmine, and Stress. Funded by Department
of Veterans Administration. Total: $300,000. Funding Period: November 1998-November 2001.
Principal Investigator: Gary Gilkeson, MD. Co-Investigator: Deborah E. Keil, Ph.D.
Evaluation of Immunotoxicological Effects of Concurrent Exposure to Ammonium Perchlorate and
Trichloroethylene in Drinking Water. Funded by the Dean of the College of Health Professions,
Medical University of South Carolina, July 1, 2000. Total: $7,000. Principal Investigator: Deborah E.
Keil, Ph.D., Co-Investigators: Gary Gilkeson, M.D., and Margie Peden-Adams, Ph.D.
Immunological Effects of Trichloroethylene Exposure. Funding yearly from October 1999 –
October 2001 by Environmental Biosciences Program, Medical University of SC. Support: $50,000
per year. Principal Investigator: Gary Gilkeson, MD. Co-Investigator: Deborah E. Keil, Ph.D.
Intracellular Signaling Pathways as Targets of Uranium Immunotoxicity. Funded by
Environmental Biosciences Program, Medical University of SC. Total: $47,647. Funding Period:
October 1998- October 1999. Principal Investigator: Karen Burnett, Ph.D. Co-Investigator: Deborah
E. Keil, Ph.D. (did not complete study due to collaborator’s change in employment)
Effects of Ammonium Perchlorate on Thyroid Hormone Levels, Hematopoiesis, and Immune
Status of B6C3F1 Female Mice. Funded by the Department of Defense. US Defense Special Weapons
Agency, June 1997. Total: $298,177. Funding Period: January 1998 - August 1999. Principal
Investigator: Deborah E. Keil, Ph.D. Co-Investigator: Alan Warren, Ph.D.
The Immune Status of Mice Exposed In Utero to JP-8 Jet Fuel: Relationship to Maternal-Fetal
Pharmacokinetics. Funded by the Department of Defense. US Defense Special Weapons Agency, June
1997. Total: $284,845. Funding Period: January 1998 - December 1999. Principal Investigator: Deborah
E. Keil, Ph.D. Co-Investigator: Alan Warren, Ph.D.
Evaluation of a Multivariate Statistical Model for Immunotoxicology Data. Funded by the Dean of
the College of Health Professions, Medical University of South Carolina, April 1, 1997. Total: $5,000.
Principal Investigator: Deborah E. Keil, Ph.D.
Keil; July 2016; Page 10 of 24
NIOSH RESEARCH STUDIES
Evaluation of Immunotoxicity due to Jet Fuel Exposure During In Utero Development. Project
Period: June 2002-2004. Principal Investigator: Deborah E. Keil, Ph.D.
Immunotoxicity to Perfluorinated Compounds Following Exposure During In Utero
Development. Project Period: June 2002-2004. Principal Investigator: Deborah E. Keil, Ph.D.
Invited Editorials and Teleconferences
Keil, D.E. 2014. What I need from the academic library: the perspective of a faculty researcher.
Journal of Library Administration. Invited Editorial in Column: posIT. Vol. 54, Issue 3, page 1-8.
May, 2014. Manuscript ID: 915168. DOI: 10.1080/01930826.2014.915168
Keil, D.E. 2012. The Value of Undergraduate Research. Invited Editorial. ADVANCE for Medical
Laboratory Professionals. Vol. 24, Issue 5, Page 16.
http://laboratorian.advanceweb.com/Archives/Article-Archives/The-Value-of-Undergraduate-
Research.aspx
Keil, D.E. 2012. Prepared and Presented National Online ASCP Teleconference: Beyond the
Dipstick: The Clinical Usefulness of Urine in Detecting Disease and Environmental Chemical
Exposures May 8, 2012
PUBLISHED PROCEEDINGS/ABSTRACTS and PRESENTATIONS
National Peer-Reviewed, Published Abstracts
Maria Rodriguez, Elisa Santori, Jacob Seymour, Lacey Murphy, Jean Pfau, Brenda Buck,
Dirk Goossens, Jamie DeWitt, and Deborah E. Keil. 2016. Epigenetic Modification of Global
Methylation Associated with Immunotoxicity Following Heavy Metal Dust Exposure. Poster for
Undergraduate Student Presentation at American Society of Clinical Laboratory Science (ASCLS),
Philadelphia Aug 1-4, 2016.
Leetham-Spencer, M., Keil, D.E., Buck, B., Goossens, D., DeWitt, J.C. Oxidative Stress and Lung
Histopathology Following Subacute Exposure to Natural Dust from the Nellis Dunes Recreation Area.
Control ID: 2093096. Society of Toxicology Conference, San Diego, Ca March 2015. (Also invited to
present at MSU student research day, April 15, 2015)
Murphy, L., Keil, D.E., Banister, C., Buck, B., Goossens, D., DeWitt, J.C. Epigenetic Markers of B
Cell Differentiating Transcription Factor Genes in Mice Exposed to Dust from Nellis Dunes
Recreational Area, Clark County, Nevada. Poster 2251; 514. Society of Toxicology Conference, San
Diego, Ca March 2015. (Also invited to present at MSU student research day with undergraduate
Laura Fisch, April 15, 2015)
Buck, B., Keil, D.E., Goossens, D., DeWitt, J. Warren, Al., McLaurin, B., Teng, Y., David, W.,
Eggers, M., Leetham-Spencer, M., Morman, S., Murphy, L., Young, S. 2014. Human Health Risk Assessment of Mineral Dust Exposure, Nellis Dunes Recreational Area, NV, USA. Invited: Soil
Mineralogy Division for the 2014 ASA-CSSA-SSSA Meetings, November 2-5, Long Beach, Ca.
https://scisoc.confex.com/scisoc/2014am/webprogram/Paper86190.html
Leetham-Spencer, Mallory; Dewitt, Jamie C.; Peden-Adams, Margie M.; Chow, Rebecca M.; David,
Winnie B.; Murphy, Lacey T.; Jensen, Marna; Walters, Nancy; Gryder, Laura; Buck, Brenda J.;
Keil; July 2016; Page 11 of 24
Goossens, Dirk; Teng, Yuanxin; Young, Sharon; Keil, Deborah E. Immunotoxicity Profile following
Exposure to Geological Dust Samples Collected from Nellis Dunes Recreational Area Map Unit
CBN2: Median Grain Size 4.5 μm. Society of Toxicology, Phoenix, AZ. March 24-27, 2014. The
Toxicologist, (Also invited to present at MSU student research day, April 15, 2014)
Murphy, L., David, Winnie B; Chow, Rebecca M; Leetham-Spencer, Mallory; Jensen, Marna; Buck,
Brenda J; Goossens, Dirk; Teng, Yuanxin; Gryder, Laura; Young, Sharon; Walters, Nancy; Keil,
Deborah E.; Peden-Adams, Margie M1; DeWitt, Jamie C. Immunotoxicity Profile following Exposure
to Silt Deposit Dust Samples from Nellis Dunes Recreational Area, Clark County, Nevada. Society of
Toxicology, Phoenix, AZ. March 24-27, 2014. The Toxicologist, (Also invited to present at MSU
student research day, April 15, 2014)
Keil, D.E., and Arlitsch, K. Scientists and Librarians Create an Environmental Toxicology Repository.
International Conference on Science and the Internet. Presentation. Dusseldorf, Germany. 1-3 August
2012.
Keil, D.E. serving as discussant representing Women in Toxicology, Society of Toxicology for the
presentation: 50 Years of ‘The Pill’: Risk Reduction and Discovery of Benefits beyond Contraception.
AAAS February 2012, Vancouver BC, Canada
Peden-Adams, M.M., Ayala, N. Young, S., Hinckley, K., Rueckert, J.A., Taylor, L., Chow, M.,
David, W., Henry, N., and Keil, D.E. 2012. Evaluation of possible modes of action for PFOS-
induced humoral immunosuppression. Submitted abstract to the Society of Toxicology, San
Francisco, CA for March 11, 2012 Conference. The Toxicologist, Vol 121, March 2012.
Buck, B.J., Soukup, D., Goossens, D., McLaurin, B., Keil, D.E., Peden-Adams, M., Proper, S., Teng,
Y, Baron, D., Ulery, A. OHV-generated and natural dust containing arsenic: Preliminary Health
Effects due to acute exposure, Nellis Dunes Recreation Area, Nevada USA. 2011 GSA Annual
Meeting in Minneapolis (9-12 October 2011). Vol. 43, No.5
Buck, B.J., Goossens, D., McLaurin, B., Soukup, D., Teng,Y., Keil, D.E., Peden-Adams, M., Baron,
D., Ulery, A. Assessment of Dust Emissions at Nellis Dunes Recreational Area, Nevada USA: Prelude
to a Human Health Risk Assessment. Presented at the Medical Geology Conference, Spring 2011
Peden-Adams, M., Berger-Ritchie, J., Young, S., Ayala, N., Keil, D. E. The role of T-cell IL-2 and
macrophage IL-10 production in PFOS-induced humoral immunosuppression. Presented at the
Society of Toxicology, Washington DC. March 6-10, 2011. The Toxicologist, Vol 120, Supplement
No. 2, March 2011.
Proper, S.P., Peden-Adams, M., Ayala, N., Berger-Ritchie, J., Lebahn, S., Young, S., Buck, B.,
Goossens, D., Soukup, D., Sudowe, R., Teng, Y., Baron, D., Harkema, J.R. and Keil, D.E. Health
Effects Due to Acute Exposure of Dust Samples Collected from Nellis Dunes Recreational Area. The
Toxicologist. March 6-10, 2011. The Toxicologist, Vol 120, Supplement No. 2, March 2011, Abstract
#670, p144.
Fair, P. A., Mollenhauer, M., Henry, N., Bossart, G., Wills, L., Keil, D. E., Peden-Adams, M. M.
Effects of a complex mixture of PCBs on immune function in B6C3F1 mice. Presented at SETAC,
November 2010.
DeWitt, J.C., Peden-Adams, M.M., Keil, D.E., and Anderson, S.E. 2010. PPAR involvement in
PFAA Immunotoxicity. PFAA Days III, US EPA, Research Triangle Park, NC. June 8-10, 2010
Keil; July 2016; Page 12 of 24
Fair, P. A., Mollenhauer, M., Henry, N., Bossart, G., Wills, L., Keil, D. E., Peden-Adams, M. M.
Effects of a Complex Mixture of PCBs on Immune Function in B6C3F1 Mice. The Toxicologist, Vol.
84, No. S-1, March 2010.
Peden-Adams, Margie M., Mollenhauer, Meagan, Morse, Maraya, Wills, Lauren, Keil, Deborah E.
Effects of Perfluorooctanesulfonic Acid (PFOS) on NF-, AP-1 and PPAR-alpha. The Toxicologist,
Vol. 84, No. S-1, March 2010.
Conway-Klaassen, J., Glatzel, J., Keil, D.E. 2009. Developing academic integrity by discouraging
academic dishonesty in online courses. Clinical Laboratory Educators Conference, Feb 2009.
Peden-Adams, M.M. and Keil, D.E. Suppression of immune function in mice following
developmental exposure to PFOS. Platform presentation at the Society of Toxicology. #2243. March
2009.
Keil, D.E., Mollenhauer, M., Berger-Ritchie, J., Lutman, M., Morse, M. and Peden-Adams, M.M.
PFOS-Induced Immune Modulation in B6C3F1 Mice Following Oral Exposure The Toxicologist, Vol.
83, No. S-1, March 2009
Peden-Adams, M.M., Mollenhauer, A.M., Keil, D.E. Comparative Immunological Responses between
Wild-Type and PPAR- PFOS. The Toxicologist, Vol. 83, No.
S-1, March 2009
Morse, M., Mollenhauer, M., Lutman, M., Berger-Ritchie, J., Keil, D.E., and Peden-Adams, M.M.
Effects of Perfluorooctane Sulfonate (PFOS) on Macrophage Function and Splenocyte Subpopulations
in B6C3F1 Mice. The Toxicologist, Vol. 83, No. S-1, March 2009
Mollenhauer, M., Fair, P., Driscol, E., Keil, D.E., and Peden-Adams, M.M. The effects of
perfluorooctane sulfonate exposure on inflammation in B6C3F1 mice. The Toxicologist, Vol. 82, No.
S-1, March 2008
Fair, P., Bossart, G., Mollenhauer, M., Keil, D.E., and Peden-Adams, M.M. Immunological alterations
in B6C3F1 mice following oral exposure to a brominated flame retardent mixture: DE-71. The
Toxicologist, Vol. 82, No. S-1, March 2008
Peden-Adams, M.M., Mollenhauer, M., Driscol, E., Berger, J., Keil, D.E., and Fair, P. Evaluation of
possible modes of action for PFOS-induced humoral immunosuppression. The Toxicologist, Vol. 82,
No. S-1, March 2008
Mollenhauer, M., Driscoll, E., Bradshaw, S., Berger, J., Fair, P.A., Keil, D.E., Peden-Adams, M.M.
Immune Alterations in B6C3F1 mice following oral exposure to PFOS. Society of Environmental
Toxicology and Chemistry (SETAC), Annual Meeting Milwaukee, WI, November 2007
Keil, D.E., EuDaly, J., Berger, J., Pangallo, J., Peden-Adams, M.M. PFOS-Induced Immune
Modulation in B6C3F1 Mice Following Oral Exposure. The Toxicologist, Vol. 81, No. S-1, March
2007
Berger, J., Stuckey, J., Pangallo, J., EuDaly, J., Scott, T., Bryant, K., Keil, D.E., Jodice, P., and Peden-
Adams, M.M. Immunological Alterations in Chicks Following In Ovo Exposure to Perfluorooctane
Sulfonate (PFOS). The Toxicologist, Vol. 81, No. S-1, March 2007
Stuckey, J., Bryant, K., Pangallo, J., Berger, J., EuDaly, J., Keil, D.E., Jodice, P., Peden-Adams, M.M.
Immunological Alterations in Chicks Following In Ovo Exposure to A Brominated Flame Retardent
Mixture: DE-71. The Toxicologist, Vol. 81, No. S-1, March 2007
Keil; July 2016; Page 13 of 24
Keil, D.E., Stuckey, J., EuDaly, J.G., Lee, A.M., Pangallo, J., Berger, J., Jodice, P., Scott, T.R.,
Peden-Adams, M.M. (2007). Effects of PFOS on Developmental Immune Function in Rodent and
Avian Models. Perfluoroalkyl Acids and Related Chemistries:Toxicokinetics and Mode-of-Action
Workshop. Society of Toxicology – Current Concepts in Toxicology. February 14-16, 2007. Westin
Arlington Gateway, Arlington, VA.
Peden-Adams, M.M., Romano, T., EuDaly, J.G., Muir, D.C.G., Houde, M., Bossart, G.D., Fair, P.A.,
Keil, D.E. (2007). Comparison of Immune Modulation in Two Mammalian Species In Relation To
PFOS Exposure. Perfluoroalkyl Acids and Related Chemistries:Toxicokinetics and Mode-of-Action
Workshop. Society of Toxicology – Current Concepts in Toxicology. February 14-16, 2007. Westin
Arlington Gateway, Arlington, VA.
McGuinn, W., Peden-Adams, M., EuDaly, J., Gilkeson, G., and Keil, D.E. The pharmacokinetics of
DEET in the mouse. The Toxicologist, Vol. 80, No. S-1, March 2006
Peden-Adams, M., Stuckey, J., EuDaly, J., and Keil, D.E. Oral exposure to perfluoroctane sulfonate
(PFOS) for 28 days suppresses immunological function in B6C3F1 mice. The Toxicologist, Vol. 80,
No. S-1, March 2006
Keil, D.E., Eudaly, J., Miller, J., Gilkeson, G., Peden-Adams, M.M.. Lifetime exposure to
trichloroethylene (TCE) does not Accelerate autoimmune disease in MRL +/+ mice. The Toxicologist,
Vol. 80, No. S-1, March 2006
Keil, D.E., Mehlmann, T., Butterworth, L. and Peden-Adams. 2005. Gestational Exposure to PFOS
Suppresses Immunological Function in F1 Mice. The Toxicologist, Vol. 79, No. S-1, March 2005
Keil, D.E., Heesemann, L.M., Miller, J., EuDaly, J.G., Gilkeson, G.G., and Peden-Adams, M.M. 2004.
The Delayed-Type Hypersensitivity Response is a Biomarker for Trichloroethylene Exposure. Society
of Environmental Toxicology and Chemistry (SETAC), 25th Annual Meeting, November 2004
Smythe, J., Keil, D.E., EuDaly, J., Griffin, W.C., and Peden-Adams, M.M. Assessment of Postnatal
Exposure to Thimerosal or Methylmercury using a Morris Water Maze Procedure in B6C3F1 Mice.
The Toxicologist, Vol. 78, No. 1-S, March 2004
Peden-Adams, M.M., EuDaly, J., Heesemann, L., Smythe, J., and Keil, D.E. Postnatal Exposure to
Thimerosal Alters Immunological Function in Adult Mice. The Toxicologist, Vol. 78, No. 1-S, March
2004
Keil, D.E., Butterworth, L. Azadi, S. and Peden-Adams, M.M. Dermal Exposure to JP-8 Jet Fuel
During Pregnancy Alters Immunological Function in F1 Mice. The Toxicologist, Vol. 78, No. 1-S,
March 2004
Keil, D.E., Heesemann, L., Adams, C., Meyers, K., EuDaly, A., Smythe, J., EuDaly, J., Gilkeson, G.,
and Peden-Adams, M.M. Immunological Function is Altered After Lifetime Exposure to
Trichloroethylene (TCE). Society of Environmental Toxicology and Chemistry (SETAC), 23rd Annual
Meeting, November 2003
Keil, D.E., Adams, C., Butterworth, L. EuDaly, J., and Peden-Adams, M. M. JP-8 Jet Fuel Does Not
Alter Serum Cytokine Levels in B6C3F1 Mice Following 7-Day Oral or Dermal Exposure. The
Toxicologist, Vol. 72, No. S-1, p.330, March 2003
Keil; July 2016; Page 14 of 24
Adams, C., Keil, D.E., Meyers, K., EuDaly, A., Smythe, J., EuDaly, J., Gilkeson, G., and Peden-
Adams, M.M. Lifetime Exposure to Trichloroethylene (TCE) Modulates Immune Function. The
Toxicologist, Vol. 72, No. S-1, p.375, March 2003
Mikell, C., Peden-Adams, M.M., Dabra, S., EuDaly, J., Keil, D.E. Hepatic Phase I and II Enzyme
Profiles after 7-Day Dermal or Oral Exposure to JP-8 Jet Fuel. The Toxicologist, Vol. 72, No. S-1,
p.330, March 2003
Peden-Adams, M.M., Adams, C., Meyers, K., EuDaly, A., Smythe, J., EuDaly, J., and Keil, D.E.
Varied Exposure Regimes to Methyl Mercury (MeHg) During Postnatal Development Leads to
Different Immune Responses. The Toxicologist, Vol. 72, No. S-1, p.376, March 2003
M.M. Peden-Adams, J.M. Keller, R. D. Day, A.R. Johnson, J. EuDaly, D.E. Keil, J.R. Kucklick, S.
Christopher, P. Maier, B. Stender, A. Segars, and D. Whitaker. Relationship of Lymphoproliferation
and Clinical Blood Parameters to Contaminants in Loggerhead Turtles. Society of Environmental
Toxicology and Chemistry (SETAC), 23rd Annual Meeting, November 2002
A.R. Johnson, J.M. Keller, J. EuDaly, D.E. Keil, J.R. Kucklick, and M.M. Peden-Adams. Critical
Assessment of a Method for Determining Immune Status of Free-Ranging Loggerhead Turtles using
Frozen Lymphocytes. Society of Environmental Toxicology and Chemistry (SETAC), 23rd Annual
Meeting, November 2002
Peden-Adams, M.M., EuDaly, J., Dudley, A., Zeigler, J., Lee, A., Robbs, J., Gikeson, G., and Keil,
D.E. Evaluation of immunotoxicity induced by single or concurrent exposure to N,N-diethyl-m-
toluamide (DEET), pyridostigmine bromide (PYR) and JP-8 jet fuel. Invited Speaker for the 36th
Annual Conference on Theories and Practices in Toxicology and Risk Assessment, Cincinnati, Ohio
April 15-18 (page 29 of program)
Keil, D.E. JP-8 Jet Fuel: From in utero to adult to autoimmunity. National Institutes for Occupational
Safety and Health. Invited speaker, September 2001
Peden-Adams, M.M., EuDaly, J.G., Dabra, S., Heesemann, L., EuDaly, A., and Keil, D.E.
Sulfluramid-induced alterations in immunotoxicological parameters. The Toxicologist, Vol. 66, No. 1-
S, p.146, March 2002
Keil, D.E., Scharstein, K., EuDaly, J.G., and Peden-Adams, M.M. Comparisons of JP-8-induced
immune alterations following two different routes of exposure in female B6C3F1 mice. The
Toxicologist, Vol. 66, No. 1-S, p.145, March 2002
Gilkeson, G.S., Peden-Adams, M.M., EuDaly, J.G., Dabra, S., EuDaly, A., Hayes, R., Heesemann, L.,
Miller, J., Smyth, J., and Keil, D.E. Exposure to single or tertiary mixtures of N,N-diethyl-m-
toluamide (DEET), pyridostigmine bromide (PYR), JP-8 jet fuel and stress in autoimmune-prone mice.
The Toxicologist, Vol. 66, No. 1-S, p.79, March 2002
Peden-Adams, M.M., EuDaly, J., Schuler, A., Lee, A., Robbs, J., Gilkeson, G., and Keil, D.E. Effects
of exposure to N,N-diethyl-m-toluamide, pyridostigmine bromide, and JP-8 or Stress on immunity and
host resistance. Society of Environmental Toxicology and Chemistry (SETAC), 22nd Annual Meeting,
November 11 – 15, Baltimore, MD
Keil, D.E., Peden-Adams, M.M., Gainey, K., Roberts, F.L., Albert, J., EuDaly, J., Redmond, S., and
Gilkeson, G. 2001. Combined effects of trichloroethylene and ammonium perchlorate on biomarkers
of immune function. Society of Environmental Toxicology and Chemistry (SETAC), 22nd Annual
Meeting, November 11 – 15, Baltimore, MD
Keil; July 2016; Page 15 of 24
Keil, D.E., Warren, D.A., Peden-Adams, M.M., and Eudaly, J. The effects of JP-8 on immune
function and thyroid hormone levels in B6C3F1 mice exposed in utero. The Toxicologist, Vol. 55, No.
1, p.218, March, 2001
Peden-Adams, M.M., Dudley, A.C., EuDaly, J., Gilkeson, G.S, and Keil, D.E. Concurrent exposure to
N,N-diethyl-m-tolumide (DEET), pyridostigmine bromide (PYR), and JP-8 jet fuel effects on
biomarkers of immune function in B6C3F1 mice. The Toxicologist, Vol. 55, No. 1, p.141, March, 2001
Dudley, A.C., Peden-Adams, M.M., EuDaly, J., and Keil, D.E. JP-8 Jet Fuel Induces CYP2B1,
CYP2E1, and GST but not CYP1A1 in Murine Liver. The Toxicologist, Vol. 55, No. 1, p.405, March,
2001
Gilkeson, G.S., Dudley, A.C., EuDaly, J., Peden-Adams, M.M., and Keil, D.E. Concurrent exposure to
N,N-diethyl-m-tolumide (DEET), pyridostigmine bromide (PYR), and exercise stress effects on
biomarkers of immune function in B6C3F1 mice. The Toxicologist, Vol. 55, No. 1, p.142, March, 2001
Wallace, S., Gilkeson, G.S., Peden-Adams, M.M., EuDaly, J., and Keil, D.E. A comparative study
evaluating the immunological effects of Trichloroethylene in NZB/NZW and B6C3F1 mice. The
Toxicologist, Vol. 55, No. 1, p.141, March, 2001
Allen, C., Peden-Adams, M.M., EuDaly, J., and Keil, D.E. Ellagic acid alters immunological function.
The Toxicologist, Vol. 55, No. 1, p.421, March, 2001
Keil, D.E., Peden-Adams, M. M., EuDaly, J., and Gilkeson, G. Immunotoxicological evaluation of
concurrent exposure N,N-diethyl-m-toluamide (DEET), JP-8 jet fuel, pyridostigmine bromide (PYR),
and/or exercise stress in B6C3F1 mice. Illnesses among Gulf War Veterans: A Decade of Scientific
Research. Presented at the Conference in Washington, DC. January 24-26, 2001
Peden-Adams, M.M., A.C. Dudley, J. EuDaly, G. Gilkeson, P.A. Fair, D.E. Keil. 2000. Evaluation of
mitogen-induced lymphoproliferative responses and NK-cell activity in Atlantic Bottlenose Dolphins
(Tursiops Truncatus). Society of Environmental Toxicology and Chemistry (SETAC), 21th Annual
Meeting (2000). Invited Platform
Keil, D.E., Jenny, M., Warren, D.A., and EuDaly, J. Immune, thyroid and hematological evaluation of
ammonium perchlorate in B6C3F1 mice. The Toxicologist, Vol. 54, No. 1, p.156. March, 2000
Jenny, M., Keil, D.E., Warren, D.A., EuDaly, J. Dietary iodine modulates ammonium perchlorate
induced immunotoxicity. The Toxicologist, Vol. 54, No. 1, p.156. March, 2000
Gilkeson, G.S., Dudley, A.C., EuDaly, J., Peden-Adams, M.M., and Keil, D.E. Effects of N,N,-
diethyl-m-toluamide (DEET) on immune function parameters in B6C3F1 mice. The Toxicologist, Vol.
54, No. 1, p.156. March, 2000
Peden-Adams, M.M., Dudley, A.C., EuDaly, J., Gilkeson, G.S., and Keil, D.E. Effects of exercise
stress or pyridostigmine bromide (PSB) on immune function parameters in B6C3F1 mice. The
Toxicologist, Vol. 54, No. 1, p.162. March, 2000
Dudley, A.C., EuDaly, J., Peden-Adams, M.M., and Keil, D.E. An aryl hydrocarbon receptor
independent mechanism of JP-8 jet fuel immunotoxicity in two strains of mice. The Toxicologist, Vol.
54, No. 1, p.158. March, 2000
Keil, D.E., Warren, D.A., Roberts, L., EuDaly, J., Dudley, A., and Peden-Adams, M. The
immunological status of mice exposed in utero to JP-8 jet fuel. Presentation at the AFOSR JP-8 Jet
Fuel Toxicology Workshop. University of Arizona, Tucson, AZ. Jan 11-12, 2000.
Keil; July 2016; Page 16 of 24
Dudley, A.C., EuDaly, J., Peden-Adams, M., Pollenz, R.S. and Keil, D.E. An Aryl Hydrocarbon
receptor independent mechanism of JP-8 jet fuel immunotoxicity in Ah Responsive (B6C3F1) and Ah
nonresponsive (DBA/2) mice. Presentation at the AFOSR JP-8 Jet Fuel Toxicology Workshop.
University of Arizona, Tucson, AZ. Jan 11-12, 2000.
Jenny, M.J., Keil, D.E., Warren, D.A., Bullard-Dillard, R., and EuDaly, J. Effects of ammonium
perchlorate in B6C3F1 mice on thyroid, hematological, and immunological parameters. The
Toxicologist, Vol. 48, No.1, p.114. March 1999
Junkins, A.D., Hundley, J.M., Sonnett, R.W., Karr, C.K., and Keil, D.E. Development of a clinical
practicum course using a simulated clinical laboratory. American Society for Clinical Laboratory
Science, San Juan, Puerto Rico. March 1999
Hundley, J.M., Junkins, A.D., Holladay, E.B., Karr, C.K., Sonnett, R.W., and Keil, D.E. An entry
level Master of Science degree in Clinical Laboratory Science. American Society for Clinical
Laboratory Science, San Juan, Puerto Rico. March 1999
Watt, J.M., Keil, D.E., Pruett, S.B., and Champlin, F.R. Influence of Serotype A encapsulation and
experimental decapsulation on phagocytosis by murine peritoneal macrophages in avian isolates of
Pasteurella multocida. 97th American Society for Microbiology General Meeting, May 1997
Keil, D.E., Luebke, R., and Pruett, S.B. Evaluation of multivariate statistical methods and their
application in quantitative modeling of immunotoxicology data. The Toxicologist, Vol. 36, No.1,
p.200. March, 1997
Watt, J.M., Holman, S.C., Wilson, W.W., Keil, D.E., Pruett, S.B., and Champlin F.R. Effect of
experimental decapsulation on cell surface properties in Serotype A Pasteurella multocida strains of
avian origin. 96th American Society for Microbiology General Meeting, New Orleans, Louisiana,
May 1996
Keil, D.E., Ensley, M.D., and Pruett, S.B. Criteria for immunological data for analysis by multivariate
methods. The Toxicologist, Vol.30, No.1, p.341-342. March 1996
Keil, D.E., Ensley, M.D., Luebke, R.W., and Pruett, S.B. A multi-indicant predictive model of
immunosuppression by dexamethasone in B6C3F1 mice. The Toxicologist, Vol.15, No.1, p.100.
March 1995
Keil, D.E., Luebke, R.W., and Pruett, S.B. Nitrite production of peritoneal macrophages after in vivo
and in vitro exposure to dexamethasone. The Toxicologist, Vol.15, No.1, p.176. March 1995
(formerly D.K. Ensley)
Ensley, D.K., Luebke, R.W., and Pruett, S.B. Quantitative evaluation of the relationship between
immune parameters and host resistance. The Toxicologist, Vol.14, No.1, p.400. March 1994
Crittenden, P., Padgett, E.L., Ensley, D.K., Carr, R., Burrus, C., and Pruett, S.B. In vivo
immunotoxicity of methylparathion in B6C3F1 female mice. The Toxicologist, Vol.14, No.1, p.123.
March 1994
Ensley, D.K., Padgett, E.L., Barnes, D., and Pruett, S.B. Methylisothiocyanate as the primary
immunotoxic metabolite of sodium methyldithiocarbamate in B6C3F1 female mice. The Toxicologist,
Vol.13, No.1, p.324. March 1993
Keil; July 2016; Page 17 of 24
Ensley, D.K., Han, Y.C., Padgett, E.L., and Pruett, S.B. Immunotoxicity of a commercial preparation
of sodium methyldithiocarbamate. The Toxicologist, Vol.12, No.1, p.50. February 1992
Regional
Keil, D.E. From DEET to Dust: Research in Progress. Invited speaker for the Department of Public
Health and Human Services Laboratory Services Bureau, 1400 E Broadway, Helena, MT. January 8,
2013.
J. Smythe, M.M. Peden-Adams, J. Eudaly, W. Griffin, and D.E. Keil. Postnatal Exposure to Methyl
Mercury (MeHg) Shows Little Effect on Cognitive Ability. Presentation at the Carolinas SETAC
Annual Meeting. Fort Johnson Marine Resources Center, Charleston, SC. April 3-4, 2003
Gainey, K., Albert, J., Laughridge, F., Peden-Adams, M.M., EuDaly, J., and Keil, D.E. Flow
cytometric evaluation of CD4/8 lymphcytic subpopulations in B6C3F1 mice exposed concurrently to
ammonium perchlorate (AP) and trichloroethylene (TCE) in drinking water for 90 days. Carolina’s
Clinical Connection Meeting (NC and SC Medical Technology Meeting), March, 2001
Albert, J., Gainey, K., Laughridge, F., Peden-Adams, M.M., EuDaly, J., and Keil, D.E. Evaluation of
natural killer cell activity after exposure to ammonium perchlorate (AP) and trichloroethylene (TCE)
in drinking water for 90 days. Carolina’s Clinical Connection Meeting (NC and SC Medical
Technology Meeting), March, 2001
Laughridge, F., Albert, J., Gainey, K., Peden-Adams, M.M., EuDaly, J., and Keil, D.E. Evaluation of
autoantibody production after exposure to ammonium perchlorate (AP) and trichloroethylene (TCE) in
drinking water for 90 days. Carolina’s Clinical Connection Meeting (NC and SC Medical Technology
Meeting), March, 2001
Robbs, J., Peden-Adams, M.M., EuDaly, J., and Keil, D.E. Resistance to Listeria monocytogenes
challenge after concurrent exposure to tertiary mixtures of pyridostigmine bromide, DEET, JP-8, or
exercise stress in mice. Carolina’s Clinical Connection Meeting (NC and SC Medical Technology
Meeting), March, 2001
Lee, A., Peden-Adams, M.M., EuDaly, J., and Keil, D.E. Resistance to B16F10 tumor challenge after
concurrent exposure to tertiary mixtures of pyridostigmine bromide, DEET, JP-8, or exercise stress in
mice. Carolina’s Clinical Connection Meeting (NC and SC Medical Technology Meeting), March,
2001
Allen, C., Peden-Adams, M., and Keil, D.E. The effects of ellagic acid on immunological responses.
Plants and Medicine Meeting. Plants, Medicine & The Economic Future of SC. SC Sustainable
Universities Initiative. Charleston, SC. September 21-22, 2000
Banks, K.P., Peden-Adams, M., EuDaly, J., and Keil, D.E. The effect of concurrent exposure to
pyridostigmine bromide, DEET, and JP-8 on specific IgM antibody production. Carolina’s Clinical
Connection Meeting (NC and SC Medical Technology Meeting). April, 2000
Wallace, S., Gilkeson, G., Peden-Adams, M., Redmond, K., and Keil, D.E. The immune effects of
trichloroethylene on autoantibody production in two strains of mice. Carolina’s Clinical Connection
Meeting (NC and SC Medical Technology Meeting). April, 2000
Allen, C., Peden-Adams, M., and Keil, D.E. The effects of ellagic acid on natural killer activity and
humoral antibody responses. Carolina’s Clinical Connection Meeting (NC and SC Medical
Technology Meeting). April, 2000
Keil; July 2016; Page 18 of 24
Hughes, N., Veser, F., Peden-Adams, M., and Keil, D.E. Therapeutic effects of glucagon on carbon
monoxide poisoning. Carolina’s Clinical Connection Meeting (NC and SC Medical Technology
Meeting). April, 2000
Lawrence, J., EuDaly, J., Warren, D.A., and Keil, D.E. Effects of JP-8 jet fuel on hematopoiesis in
B6C3F1 mice. Carolina’s Clinical Connection Meeting (NC and SC Medical Technology Meeting).
March, 1999
Marquis, T., Jenny, M.J., Warren, D.A., and Keil, D.E. Effects of JP-8 jet fuel on macrophage
function in B6C3F1 mice. Carolina’s Clinical Connection Meeting (NC and SC Medical Technology
Meeting). March, 1999 Keil, D.E. Invited Speaker. “Malaria – Development of a Vaccine.” Carolinas Clinical Connection.
Charlotte, NC. 1998
Keil, D.E. Invited Speaker. “Drugs and their Effect on the Immune System” Tennessee State Society
of American Medical Technologists, Continuing Education Seminar and State Meeting, Nashville, TN.
1995
(formerly D.K. Ensley)
Ensley, D.K., Luebke, R.W., and Pruett, S.B. Quantitative relationships between immunological
parameters and host resistance: A multivariate statistical approach. Presentation at the Eighth Annual
Symposium on Immunotoxicology, Virginia Beach, VA. September 1993
Ensley, D.K., Padgett, E.L., Barnes, D., and Pruett, S.B. The effects of methylisothiocyanate, the
primary immunotoxic metabolite of sodium methyldithiocarbamate. Regional Society of
Microbiology and Biochemistry, Starkville, MS. November 1992
Ensley, D K., Han, Y.C., Padgett, E.L., and Pruett, S.B. An investigation of the immunotoxic effects
of sodium methyldithiocarbamate in B6C3F1 female mice. South Central Chapter of the Society of
Toxicology, Starkville, MS. September 1991
Pool, G.L., Ensley, D.K., Samples, B.L., and Lumb, R.H. PAF stimulation of the respiratory burst in
phagocytes of the rainbow trout. Southeastern Regional Lipid Conference, Cashiers, NC. October
1990
University
Maria Rodriguez, Elisa Santori, Jacob Seymour, Lacey Murphy, Jean Pfau,
and Deborah E. Keil. 2016. Epigenetic Modification of Global Methylation Associated with
Immunotoxicity Following Heavy Metal Dust Exposure. Poster for Undergraduate Student Day
Montana State University, April 15, 2016.
Morse, M., Mollenhauer, M., Lutman, M., Berger-Ritchie, J., Keil, D.E., and Peden-Adams, M.M.
Effects of Perfluorooctane Sulfonate (PFOS) on Macrophage Function and Splenocyte Subpopulations
in B6C3F1 Mice. UNLV Division of Health Sciences Interdisciplinary Research Scholarship Day.
April 16, 2009. Page 19.
Menzel, N., Keil, D.E. and Landers, M. Biomarkers for low back pain-related disability. Division of
Health Sciences: Interdisciplinary Research Scholarship Day. April, 16, 2009.
Keil; July 2016; Page 19 of 24
Keil, D.E., Mollenhauer, M., Berger-Ritchie, J., Lutman, M., Morse, M. and Peden-Adams, M.M.
PFOS-Induced Immune Modulation in B6C3F1 Mice Following Oral Exposure. Division of Health
Sciences: Interdisciplinary Research Scholarship Day. April, 16, 2009.
Morse, M., Mollenhauer, M., Lutman, M., Berger-Ritchie, J., Keil, D.E., and Peden-Adams, M.M.
Effects of Perfluorooctane Sulfonate (PFOS) on Macrophage Function and Splenocyte Subpopulations
in B6C3F1 Mice. Division of Health Sciences: Interdisciplinary Research Scholarship Day. April, 16,
2009.
Menzel, N., Keil, D., Landers, M. Biomarkers for Low Back Pain. Division of Health Sciences:
Interdisciplinary Research Scholarship Day. Abstract #61. April, 10, 2008.
Berger, J., Stuckey, J., Peden-Adams, M., Keil, D. 2006. The Role of PFOS on Immunological Cell
Types and Mechanisms of Immunosuppression. Summer Undergraduate Research Closing Poster
Session, August 11, 2006. Sponsers: EPSCoR, NSF REU, NIH – INBRE, HiPSEC REU
Banks, K.P., Peden-Adams, M., EuDaly, J., and Keil, D.E. The effect of concurrent exposure to
pyridostigmine bromide, DEET, and JP-8 on specific IgM antibody production. 1st Annual College of
Health Professions Student Research Day. April, 2000
Wallace, S., Gilkeson, G., Peden-Adams, M., Redmond, K., and Keil, D.E. The immune effects of
trichloroethylene on autoantibody production in two strains of mice. 1st Annual College of Health
Professions Student Research Day. April, 2000. Awarded 2nd place.
Allen, C., Peden-Adams, M., and Keil, D.E. The effects of ellagic acid on natural killer activity and
humoral antibody responses. 1st Annual College of Health Professions Student Research Day. April,
2000. Awarded 1st place.
Hughes, N., Veser, F., Peden-Adams, M., and Keil, D.E. Therapeutic effects of glucagon on carbon
monoxide poisoning. 1st Annual College of Health Professions Student Research Day. April, 2000
Jenny, M.J., Keil, D.E., and EuDaly, J. Dietary iodine alters suppression of thyroid hormone
biosynthesis and ammonium perchlorate induced immunotoxicity. 34th Annual MUSC Student
Research Day. November 1999
Dudley, A.C., EuDaly, J., Peden-Adams, M.M., and Keil, D.E. An aryl hydrocarbon receptor
independent mechanism of JP-8 jet fuel immunotoxicity in two strains of mice. 34th Annual MUSC
Student Research Day. November 1999
Jenny, M.J., Keil, D.E., Warren, D.A., Bullard-Dillard, R., and EuDaly, J. Effects of ammonium
perchlorate in B6C3F1 mice on thyroid, hematological, and immunological parameters. 33rd Annual
MUSC Student Research Day. November 1998
TEACHING/MENTORING EXPERIENCE
Mentoring of Graduate Students, Committee Chair
1999 Matthew Jenny, M.S. The effects of ammonium perchlorate on thyroid, hemato-
logical and immunological function in B6C3F1 female mice
1999 Jessie Lawrence, M.S. The effects of JP-8 jet fuel on hematopoiesis in B6C3F1 mice
1999 Tracy Marquis, M.S. The effects of JP-8 jet fuel on macrophage function in
B6C3F1 mice
1999 Julie Kasperski, M.S. Comparative study on the cytokine levels in irradiated and
filtered platelet concentrates
Keil; July 2016; Page 20 of 24
2000 Camilla Allen, M.S. The effects of ellagic acid on natural killer cell activity and
humoral antibody responses
2000 Kimberlee Banks, M.S. The effects of concurrent exposure of DEET, pyridostigmine
bromide, and JP-8 on IgM humoral antibody responses
2000 Stacey Wallace, M.S. The effects of trichloroethylene on autoantibody production
in NZB/NZW and B6C3F1 mice
2000 Nikki Hughes, M.S. Use of glucagon in the treatment of carbon monoxide
poisoning
2000 Andrew Dudley, M.S. Effects of concurrent exposure to DEET, pyridostigmine, and
exercise stress on immunological parameters
2001 Keisha Gainey, M.S. Combined effects of trichloroethylene and perchlorate
on T lymphocyte subpopulations after 90-days exposure
2001 Jaime Albert, M.S. Combined effects of trichloroethylene and ammonium
perchlorate on spleen and thymus weight and natural killer
cell activity
2001 Farrah Laughridge, M.S. Exposure to trichloroethylene (TCE) and ammonium
perchlorate (AP singly and in combination alter autoantibody
production in female B6C3F1 mice.
2001 Jessica Robbs, M.S. The effects of tertiary and single exposures to JP-8 Jet Fuel,
DEET, pyridostigmine bromide and exercise stress in
resistance to Listeria monocytogenes
2001 Jessica Zeigler, M.S. The effects of single and tertiary exposure to JP-8 Jet Fuel,
N,N-Diethyl-m-toluamide (DEET), Pyridostigmine Bromide,
and Exercise Stress on CYP2B1 and GST
2001 Amanda Lee, M.S. The tertiary effects of DEET, pyridostigmine bromide, and
JP-8 jet fuel or stress on a host resistance tumor model
2002 Shola Gates, M.S. Investigation of autoantibodies to dsDNA and ssDNA in
MRL-lpr/lpr mice challenged with DEET, PYR, JP-8, and
stress. (co-chair with Dr. Peden-Adams)
2002 Amber Johnson, M.S. Investigative immunotoxicological methods comparisons
using fresh and frozen marine leukocytes.
(co-chair with Dr. Peden-Adams)
2002 Robert Haynes, M.S. Effects of concurrent exposures to DEET, PYR, JP-8, and
stress on the development of CD4/CD8 lymphocyte
subpopulations in autoimmune-prone mice.
(co-chair with Dr. Peden-Adams)
2002 Julie Miller, M.S. Effects of concurrent exposures to DEET, PYR, JP-8, and
stress on the development of autoantibodies in autoimmune-
prone mice. (co-chair with Dr. Peden-Adams)
2008 Jennifer Berger-Richie Undergraduate mentor
2009 Maraya Morse Undergraduate mentor
2009 Jennifer Berger-Richie Graduate mentor and committee member; Masters in Public
Health
2010-2014 Sharon Young, B.S. M.A. and Ph.D. Graduate mentor and committee member;
Anthropology Department, UNLV
2013-2015 Lacey Murphy Masters in Microbiology and Immunology, MSU.
2013-2015 Mallory Spencer Masters in Microbiology and Immunology, MSU.
2013-2014 Shavonn Whiten Masters in Land Resources and Environmental Studies
Committee member, not primary
2010 Nancy Walters, DVM Masters in Public Health, UM. Mentored research requirement:
Treg expression in metal exposed mice (NDRA study).
Keil; July 2016; Page 21 of 24
Undergraduate and High School Mentoring
1999 Tameka Greene McClellenville High School, SC
1998 Nina Montgomery, BS Claflin College, Orangeburg, SC
1998 Charlease Kelly, BS Claflin College, Orangeburg, SC
2001 Sundeep Dabra, BS Clemson Univerisity, SC
2001 Joshua Smyth, BS Clearwater University, FL
2001 Lauren Heesemann, BS College of Charleston, SC
2001 Kate Scharstein, BS College of Charleston, SC
2006 Robert Perez, BS CLS Senior CLS, UNLV
Hormone validation studies with using blood spots and saliva.
Collaboration with Dr. Peter Gray, Medical Anthropology, UNLV
2006 Justina Pangallo, BS CLS; Senior CLS, UNLV; The Role of PFOS on Immunological Cell
Types and Mechanisms of Immunosuppression.
Collaboration with Dr. Peden-Adams, MUSC/NOAA
2006 Jennifer Berger, BS CLS; Senior CLS, UNLV; EPSCOR recipient The Role of PFOS on
Immunological Cell Types and Mechanisms of Immunosuppression.
Collaboration with Dr. Peden-Adams, MUSC/NOAA
2009-2010 Nadia Ayala Senior CLS, UNLV; undergraduate research credit
2010 Zack Kohler Senior CLS, UNLV; undergraduate teaching credit
2010 Jovanica Perez Senior CLS, UNLV; undergraduate teaching credit
2011 Justin Rueckert Senior MLS, U Utah; undergraduate research
2011 Kira Hinckley Senior MLS, U Utah; undergraduate research
2011 Lacey Murphy Senior MLS, U Utah; undergraduate research
2010-2014 Marna Jensen Junior MLS major, Montana State University
2014-2015 Laura Fisch Junior, PreMed Major, Montana State University
Undergraduate working on INBRE
2016 Meghann Karsch Undergraduate Montana State University
2016- Zoie Kapish Undergraduate Montana State University
2016- Jacob Seymour Undergraduate Montana State University
2016- Caleb Stair Undergraduate Montana State University
2016 Logyn Blom Undergraduate Montana State University
2016- Maria Rodriguez Undergraduate Montana State University
2016- Elisa Santori Undergraduate Montana State University
2016- Jessica Eggers Undergraduate Stanford University
NIOSH Student Mentor Program
2002 Carmenza Mikell, B.S. West Virginia University, WV
2003 Steve Proper, B.S. (2005) Kettering University, Flint, MI
2003 Tracey Mehlmann, B.S. Wheeling Jesuit University, Wheeling, WV
K-12 Mentoring
2013 Volunteer mentor for 3rd grader experiments, Helena Grade School, 2013- current
Courses Taught in Department of Microbiology and Immunology, Montana State University
Capstone Seminar BIOM 494, 2 sections of 12 students SPR 2013
Capstone Seminar BIOM 494, 2 sections of 10 students SPR 2014
Toxicology: The Science of Poisons (15 students; 3 credit) SPR 2014
Fundamentals of Hematology (60 students; 3 credit) FALL 2014
Toxicology: The Science of Poisons (40 students; 3 credit) SPR 2015
Fundamentals of Hematology LAB (40 students; 1 credit) FALL 2015
Keil; July 2016; Page 22 of 24
Fundamentals of Hematology (60+ students; 3 credit) FALL 2015
Courses Taught in Clinical Laboratory Sciences Masters Program, MUSC
Professional Practice in Immunohematology 1998-2001
Topics in Immunohematology 1998-2001
Research and Statistics 1998-2001
Immunohematology and Transfusion Practices 1997-2001
Introduction to Laboratory Management 1997-2001
Chemical Pathology (Clinical Chemistry II) 2001
Courses Taught in Clinical Laboratory Sciences Undergraduate Degree Program, UNLV
Clinical Chemistry I, II (Instrumentation and Pathophysiology) 2005-
current Immunohematology/Transfusion Medicine 2006-
current
Courses Taught in Medical Laboratory Sciences Program, University of Utah
Clinical Chemistry I and II (MDLB 4200, 4210) 2011-current
Research (MDLB 5210) 2012-
current Body fluids (MDLB 3680) 2010-
current
Courses Taught as a Graduate Assistant, Mississippi State University
Medical Parasitology 1992-1996
Quantitative Methods in Medical Technology 1992-1996
Botany 1991-1993
SERVICE
International
Executive Board of Directors, American Board of Toxicology (ABT)
Member of the Executive Board of the American Board of Toxicology (ABT)
Serving in the capacity of various roles: Secretary; Co-Chair Globalization Committee; Chair
Policy and Procedures Committee; Member of Eligibility and Exam Committee
2012-2016
International Conference for Medical Laboratorians in Sub-Saharan Region of
Africa. July, 2012 in Ghana. Presented workshop Medical Laboratory QC/QA 2012 2012
Invited speaker, Brazilian Congress on Toxicology. October 7-10, 2013.
Represented American Board of Toxicology. 2013
National
Undergraduate Education SubCommittee, Society of Toxicology 2014- 2017
Education Committee, Immunotoxicology Specialty Section 2014
Alice Hamilton Award, NIOSH. Reviewer. 2012, 2013
Roundtable Speaker, Undergraduate Mentoring.
Clinical Laboratory Educators Conference – ASCLS. Salt Lake City, UT Feb 2012
Health Improvement Institute (HII), Arrangements Development Committee (ADC) 2011 2011
Keil; July 2016; Page 23 of 24
Serve on Discussant Panel at AAAS: 50 years of “The Pill”: Risk Reduction and
Discovery of Benefits Beyond Contraception, Reflections and Forecast 2012
Secretary/Treasurer, Women in Toxicology, Society of Toxicology 2010-2012
EPA Science Advisory Board (SAB) Trichloroethylene Health Assessment Rev Panel 2010
Undergraduate Research, Society of Toxicology 2010
Ad hoc NIH/Immunotoxicology Committee, SOT 2010
Session Chair for Society of Toxicology Conference, Autoimmunity 2001
Methods Committee, Immunotoxicology Specialty Section, Society of Toxicology 2000
Awards Committee, Immunotoxicology Specialty Section, Society of Toxicology 2003
University, Montana State University
Center for Research Computing Visioning Committee 2013-current Classroom Committee, Faculty Senate 2013-2015
University, University of Utah
Cyber Infrastructure Data Management Subcommittee 2012 Admissions Committee, MLS Program 2012
University, University of Nevada, Las Vegas
Academic Freedom and Ethics Committee 2009-2010
Institutional Biosafety Committee (IBC) 2007-2010
AHS adhoc Research Committee, Chair 2007-2010
Selection Committee for Dean of Graduate Studies and VP for Research 2006-2007
University, Medical University of South Carolina, Charleston
University Gender Issues Committee 1999-2000
Electronic Research Administration Working Group 1998-2001
Basic Science Building Science Advisor 1998-1999
Operations Committee, Strom Thurmond Biological Research Building 1998-2001
University Research Council 1998-2001
Faculty Senate 1998-2000
Institutional Animal Care and Use Committee (IACUC) 2000-2002
College of Health Professions, Medical University of South Carolina, Charleston
Search Committee for Assistant Dean of Research, College of Health Professions 1999-2000
Research Task Force, College of Health Professions 1998-1999
Chair of the Research Subcommittee, College of Health Professions 1997-2000
Strategic Research Committee, College of Health Professions 2000-2001
Dept. of Medical Laboratory Science, Medical University of South Carolina, Charleston
Marine Biomedical Environmental Science Committee 1998-2002
Departmental Recruitment Committee 1997-2001
Departmental Safety Committee 1997-2001
SOCIETY MEMBERSHIP
Diplomate and Board Member, American Board of Toxicology 2006-current
American Association of Clinical Chemistry (AACC) 2005-2012
South Carolina Academy of Science 1999-2002
American Society of Clinical Laboratory Science 1997-2002;
2005-current
Associate Membership with the Society of Toxicology 1997-current
Association for the Society for Clinical Pathologists (ASCP) 1992-current
Keil; July 2016; Page 24 of 24
CONTINUING EDUCATION and PROFESSIONAL MEETINGS ATTENDED
54th Annual Society of Toxicology Meeting, San Diego, CA 2015
53rd Annual Society of Toxicology Meeting, Phoenix, AZ 2014
Interprofessional Education Workshop by University of Washington @ MSU campus 2013
52nd Annual Society of Toxicology Meeting, San Antonio, TX 2013
Specialized Techniques for Dose-Response Assessment and Risk
Assessment of Chemical Mixtures, Continuing Education SOT, San Antonio, TX 2013
Science and the Internet, Aug 1-3, Dusseldorf, German 2012
SOT Contemporary Concepts in Toxicology (CCT) workshop entitled “Multi-scale
Integration of Human Health and Environmental Data,” co-sponsored by the US
Environmental Protection Agency (USEPA), USEPA campus in Research Triangle
Park, NC May 8–11, 2012 2012
51st Annual Society of Toxicology Meeting, San Francisco, Ca 2012
Clinical Laboratory Educators (CLEC) Meeting, Salt Lake City, UT 2012
50th Annual Society of Toxicology Meeting, Washington, DC 2011
Arrangements Development Committee (ADC) for the Project to harmonize health
research guidelines, held on November 1, 2011 2011
Recertification of Diplomat of American Board of Toxicology- Passed 2010
49th Annual Society of Toxicology Meeting, Salt Lake City, UT 2010
NIH Regional Seminar. Las Vegas, NV. June 25 2009
Beckman-Coulter Seminar, San Francisco, CA June 11 2009
Professional Practice in Clinical Chemistry: A Review & Update,
AACC, Alexandria, VA. 2009
48th Annual Society of Toxicology Meeting, Baltimore, MD 2009
47th Annual Society of Toxicology Meeting, Seattle, WA 2008
AACC Conference, San Diego, CA July 15-18 2007
Professional Practice in Clinical Chemistry: A Review & Update,
AACC, Washington, D.C. 2007
46th Annual Society of Toxicology Meeting, Charlotte, NC 2007
Cambridge HealthTech Institute, Translational Research 2006
45th Annual Society of Toxicology Meeting, San Diego, CA 2006
The Society of Environmental Toxicology and Chemistry, Baltimore, MD
November 14-17 2005
Visiting Professor, Mystic Aquarium, Mystic, Connecticut.
Collaboration with Vice President of Marine Research, Dr. Tracy Romano 2005
Professional Practice in Clinical Chemistry: A Review & Update,
AACC, Alexandria, VA 2005
Diplomat American Board of Toxicology Review Course, Kansas City, KS
Director: Dr. Curtis Klaassen 2004
43rd Annual Society of Toxicology Meeting, Baltimore, MD 2004
Workshop on Juvenile Animal Studies: Testing Strategies and Design
ILSI Health and Environmental Sciences Institute, Washington, D.C. 2003
Michigan Society of Toxicology: Proteomics, Genomics, Metabonomics 2003
42nd Annual Society of Toxicology Meeting, Salt Lake City, Utah 2003
41st Annual Society of Toxicology Meeting, Nashville, TN
Molecular Toxicology and Toxicogenomics Courses 2002
40th Annual Society of Toxicology Meeting, San Francisco, CA 2001
39th Annual Society of Toxicology Meeting, Philadelphia, PA 2001
Conference on Federally Sponsored Gulf War Veterans’ Illnesses Research
Pentagon City, VA 2001
The Efficacy and Safety of Medicinal Herbs. International Conference.
The Institute of Nutrition, University of NC, Chapel Hill, NC. 2000
Southeastern Society of Toxicology Meeting. Athens, GA 2000
Keil; July 2016; Page 25 of 24
Plants, Medicine & The Economy: Working Conference.
SC Sustainable Universities Initiative, Charleston, SC 2000
AFOSR JP-8 Jet Fuel Toxicology Workshop. Tucson, AZ 2000
WebCT Course, MUSC 1999
Conference on Federally Sponsored Gulf War Veterans’ Illnesses Research
Pentagon City, VA 1999
Workshop on Human and Murine Stem Cell Evaluation. Stem Cell
Technologies, Inc. Vancouver, BC 1999
38th Annual Society of Toxicology Meeting, New Orleans, LA 1999
Linking Environmental Agents and Autoimmune Diseases. National Institute of
Environmental Health Sciences. Research Triangle Park, NC 1998
Assessing and Managing Risks in a Democratic Society. Society for Risk Analysis
Annual Meeting and Exposition, Phoenix, AZ. 1998
36th Annual Society of Toxicology Meeting. Cincinnati, OH 1997
35th Annual Society of Toxicology Meeting, Anaheim, CA 1996