How to protect your

packaging?Specific solutions for pharmaceutical products

December 2016

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The second largest listed Packaging company in the world

$15 billionTotal sales

42,000Employees

275Operating and

business locations

12.3 millionTons of paper

shipped

Who is WestRock?

provides innovative packaging solutions for

consumer and corrugated markets.

Our strengths include:

• full control of our supply chain

• local design & regulatory support

• speed of execution

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Pharmaceutical Product range

Smart Packaging

Adherence Packaging Child Resistant Packaging

Bespoke design

Analytical database

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WestRock’s Production Facilities for Healthcare

Advanced ProductionOTC; Consumer Health

Kimball,TN

Adherence & SecondaryPackaging

Dublin, Ireland

Adherence primary and secondary packaging

International LabsSt. Petersburg, FL

Smart TechnologiesAardex

SwitzerlandConsumer Health; OTC

Marion, NC

Advanced ProductionOTC; Luxury

Montreal, Quebec

Dedicated pharmaadherence packaging &

manufacturing Mebane, NC

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A Global Presence

Smart PackagingAdherence Packaging

Smart TechnologiesAardex

Belgium

Packaging Matters

Packaging Matters

Safe packaging is linked to trust,

favorability and purchasing

behavior.

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Tamper Evident Features

Tamper Evidence in standard RTE boxes

Tamper evidence for each end

WestRock builds TE features in the Design

of the packaging to:

Use identical production lines

Run at industrial speed

Avoid additional components

Multi-vial protection with Tamper Evidence

Tamper evidence for each vial

Adaptable size and number of vials

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Child Resistance& Senior Friendly

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Shellpak®

No need to repass CR test

Very slim format

Tear resistant board

Many size available

Very good scalability

Optimal for retail

Tested F=1 “containers”

Shellpak Renew

Shellpak Renew - with Optilock technology

Ready for commercialization

Compact version →

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Surepak®

Pull-and-peel blisters with integrated child-resistance in every

pill cavity.

Simple design & flat format

Generous space for labeling and

educational information.

Adaptable size

Cost effective

Perfpak®

Advantage

F=1 packaging for retail

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Listed on the American Society of Testing and Materials

(ASTM) as a CR package and feature.

Used in thousand of trials but also for commercial projects.

MOQ from 200 pieces up to millions

Fully customizable for complex

titrations

Heat or cold sealing

Generous space for labeling and

communication on calendar

Available in tailor-made size and

format for blisters, syringes and

bottles

Dosepak®

Packaging for Clinical and Commercial

The most flexible CR solution

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Dosepak®

: Sets the Standard in Adherence We are experts in increasing the medical adherence

Integrates child resistance while remaining senior-friendly

Small size makes the package more portable and discreet

Heat-sealed for better blister and pack integrity

Provides space for extended labeling and patient educational materials

Calendar helps patients adhere to daily dosing regimens

Delivers pills in single,controlled doses

The packaging is the difference

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The unique identifier

Unique Identification code Integrated control of the data

Customer generates non

sequentialcodes

WestRock prints and

verifies unicityand readability

Customer receives the list of codes

printed

Serial numbers can be converted in 2D

barcodes

better automation

The history of codes are stored by WestRock

and by the customer.

back up database

Codes integrated in the batch release

Improved traceability

Unique Identification code Learning from Clinical Trials

Last minute customization

• Booklet language

• Print of lot and expiry date

• Adapted communication

Storage on Unique ID code

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Smart Packaging &

Adherence data

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Pill count Dosepak®

Tracks date, time and location of dispensed pill

Adherence-enhancing design is based on Dosepak®

Hidden electronics are unobtrusive to patients

Easy to manufacture using standard techniques

Cost effective and simple to use

Develops interaction with patients

Assembly of the Dosepak®

. . .

Outer Inner opened Insertion of the

blister

Sealing

WestRock will give on site support for the

QA and Packaging initiation.

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Database

AARDEX Electronic Adherence SolutionsAccurately records “Pill in Hand” and transfers data for immediate analysis

Customer Interface Dashboard

Medication Event Monitoring System medAmigo Data Analysis System

Readers• BTLE, NFC,

USB

• Smartphone,

Tablet, Hub

Modeling and

Simulation Center

MEMS® Cap

Electronic Dosepak®

Helping Hand®

500 Reseach Centers and Universites; >700 peer reviewed articles

The Dangers of Poor Medication AdherenceInaccurate dosing can lead to poor exposure to the trial drug

Understanding your subjects’ adherence patterns can

help the patient to improve his medical journey.

Early Discontinuation

Drug Holiday

Problem with Evening Dose

Sporadic Dosing

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Successful adherence

programs feature:

Coordinated action

across providers and

the healthcare system

Support and education

for patients

Consistent reinforcement

Integrated tactics building

upon each other

The right

knowledge

and tools to

establish

positive

patient

habits

World Health Organization. Adherence to Long-Term Therapies. 2003.

Any questions?

Thank you for attending!

For further information and samples please contact:

PLASTRADE

www.plastrade.hu