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Decreased mucosal interleukin-4 (IL-4) production in gut inflammation.

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Journal List > J Clin Pathol > v.47(11); Nov 1994

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Breese, E.Walker-Smith, J.

MacDonald, T.

J Clin Pathol. 1994 November; 47(11): 10151018.

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Decreased mucosal interleukin-4 (IL-4) production in

gut inflammation.

R Karttunnen, E J Breese, J A Walker-Smith, and T T MacDonald

Department of Paediatric Gastroenterology, St Bartholomew's Hospital, London.

Abstract

AIMS--To determine the prevalence of cells secreting interleukin-4 (IL-4)in the gut mucosa of children with chronic inflammatory bowel disease.

METHODS--Mononuclear cells were isolated from intestinal biopsy

i f t l hild ( 10) d hild ith ti

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Selected References

This list contains those references that cite another article in PMC or have a citation in

PubMed. It may not include all the original references for this article.

q Brynskov J, Tvede N. Plasma interleukin-2 and a soluble/shed interleukin-2 receptor

in serum of patients with Crohn's disease. Effect of cyclosporin. Gut. 1990 Jul;31

(7):795799. [PubMed]

q Choy MY, Walker-Smith JA, Williams CB, MacDonald TT. Differential expressionof CD25 (interleukin-2 receptor) on lamina propria T cells and macrophages in the

intestinal lesions in Crohn's disease and ulcerative colitis. Gut. 1990 Dec;31

(12):13651370 [PubMed]
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q Gurbindo C, Russo P, Sabbah S, Lohoues MJ, Seidman E. Interleukin-2 activity of

colonic lamina propria mononuclear cells in a rat model of experimental colitis.

Gastroenterology. 1993 Apr;104(4):964972. [PubMed]

q Mosmann TR, Coffman RL. Heterogeneity of cytokine secretion patterns and

functions of helper T cells. Adv Immunol. 1989;46:111147. [PubMed]

q Breese EJ, Michie CA, Nicholls SW, Murch SH, Williams CB, Domizio P, Walker-

Smith JA, MacDonald TT. Tumor necrosis factor alpha-producing cells in the

intestinal mucosa of children with inflammatory bowel disease. Gastroenterology.

1994 Jun;106(6):14551466. [PubMed]

q MacDonald TT, Spencer J, Viney JL, Williams CB, Walker-Smith JA. Selective

biopsy of human Peyer's patches during ileal endoscopy. Gastroenterology. 1987

Dec;93(6):13561362. [PubMed]

q Briscoe DM, Cotran RS, Pober JS. Effects of tumor necrosis factor,

lipopolysaccharide, and IL-4 on the expression of vascular cell adhesion molecule-1

in vivo. Correlation with CD3+ T cell infiltration. J Immunol. 1992 Nov 1;149

(9):29542960. [PubMed] [Full Text]

q Schleimer RP, Sterbinsky SA, Kaiser J, Bickel CA, Klunk DA, Tomioka K,

Newman W, Luscinskas FW, Gimbrone MA Jr, McIntyre BW, et al. IL-4 induces

adherence of human eosinophils and basophils but not neutrophils to endothelium.Association with expression of VCAM-1. J Immunol. 1992 Feb 15;148(4):1086

1092. [PubMed] [Full Text]

q Phillips JO, Everson MP, Moldoveanu Z, Lue C, Mestecky J. Synergistic effect of IL-

4 and IFN-gamma on the expression of polymeric Ig receptor (secretory component)

and IgA binding by human epithelial cells. J Immunol. 1990 Sep 15;145(6):1740

1744. [PubMed] [Full Text]

q McCabe RP, Secrist H, Botney M, Egan M, Peters MG. Cytokine mRNA expressionin intestine from normal and inflammatory bowel disease patients. Clin Immunol

Immunopathol. 1993 Jan;66(1):5258. [PubMed] [Full Text]
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=8462823http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=2528896http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=8194690http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=3500086http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=1383333http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&retmode=ref&cmd=prlinks&id=1383333http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=1371130http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&retmode=ref&cmd=prlinks&id=1371130http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=2118154http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&retmode=ref&cmd=prlinks&id=2118154http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=8440073http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&retmode=ref&cmd=prlinks&id=8440073http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&retmode=ref&cmd=prlinks&id=8440073http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=8440073http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&retmode=ref&cmd=prlinks&id=2118154http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=2118154http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&retmode=ref&cmd=prlinks&id=1371130http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=1371130http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&retmode=ref&cmd=prlinks&id=1383333http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=1383333http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=3500086http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=8194690http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=2528896http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=8462823


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Summary

Selected References

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PDF (716K)

Contents

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PubMed articles by:

Karttunnen, R.

Breese, E.

Walker-Smith, J.

MacDonald, T.


Copyright notice




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Summary

Selected References

Page Browse

PDF (716K)

Contents

Archive

Related material:

PubMed articles by:

Karttunnen, R.

Breese, E.

Walker-Smith, J.

MacDonald, T.


Copyright notice




Page 1016


PubMed related arts

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D d l i t l ki 4 (IL 4) d ti i t i fl ti


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D d m l i t l ki 4 (IL 4) d ti i t i fl mm ti


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Summary

Selected References

Page Browse

PDF (716K)

Contents

Archive

Related material:

PubMed articles by:

Karttunnen, R.

Breese, E.

Walker-Smith, J.

MacDonald, T.


Copyright notice




Page 1017


PubMed related arts

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Decreased mucosal interleukin 4 (IL 4) production in gut inflammation


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Decreased mucosal interleukin 4 (IL 4) production in gut inflammation.


Summary

Selected References

Page Browse

PDF (716K)

Contents

Archive

Related material:

PubMed articles by:

Karttunnen, R.

Breese, E.

Walker-Smith, J.

MacDonald, T.


Copyright notice




Page 1018


PubMed related arts

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decreased mucosal il-4 production in gut inflammation

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