deflect specsheet

4
120 VeggieCaps per bottle. Suggested retail price: $34.95 Typically, lectins can bind to many of the carbohydrate antigens found in the gut and immune system, causing a variety of health problems. This is usually accomplished by direct agglutination of the target cells. Lectins can occur in very common foods in the diet, and the majority is specic for the carbohydrates of the ABO blood typing system. Clinical Indications Intestinal dysbiosis Bowel hyperpermiabil ity Immune dysfunction Food sensit ivities a nd systemic inammation Metabolic Syndrome • Carbohydrate intolerant individuals who typically gain weight on high carbohydrate diets. In one study, the edible parts of 29 of 88 foods tested, including common salad ingredients, fresh fruits, roasted nuts, and processed cereals were found to possess signicant lectin-like activity as assessed by hemagglutination and bacterial agglutination assays. Several common lectins, in particular , wheat germ agglutinin, are known to bind to the insulin receptor and mimick the hormonal effects of insulin on adipose tissue, an under-appreciated action which can account for why individuals on high carbohydrate diets often have difculty contolling their weight. Thus, lectin blocking is a safe and rational method for enhancing weight loss. In the words of one lectin researcher: “Most lectins in our diet are resistant to breakdown during gut passage and are bound and endocytosed by epithelial cells. These lectins are powerful exogenous growth factors for the small intestine, can induce dramatic shifts in its bacterial ora and interfere with its hormone secretion. In addition, lectins that are transported across the gut wall into the systemic circulation can modulate the body’s hormone balance, metabolism and health. Although these physiological effects are mediated or reinforced by immune responses, they are primarily the result of the specic chemical reactivity of lectins with cell surface receptors of the gut.” Actions and Indications The Deect ® formula provides a source of free blocking amino sugars which bind and block lectins before they can attach to the cells. Since each blood type is succeptible to lectins with different carbohydrate specicities, Dr . D’Adamo designed formulas to block lectins by using mono and polysaccharides specic for each blood type. The amino sugars in Deect ® encourage healthy bowel ora, although they do not provide a source of ora themselves. These same amino sugars are healthy enhancers of joint gliding surface and synovia as well. One way this repair mechanism works is by ‘prying off’ lectins which have already adhered to cellular receptors, such as insulin. Since insulin blockage by dietary lectins has been linked to both insulin resistance and obesity , using Deect ® can help accelerate weight reduction in diet-compliant individuals by speeding up the time it takes for the regeneration of new insulin receptors or the ‘cleansing’ of the old ones. This can take upwards of one year in some individuals who just follow the diet, and explains why some dieters do not see weight loss in the early stages of the program. It is because of this ‘lectin-locking’ function that many other diets (which do have accelerated weight loss in their early stages) cause their followers to lose muscle mass and fat -when what we want is to lose only the fat. If the weight loss in the Blood Type Diet is occasionally slow, at least it is healthy: Losing only body fat means that a person’s weight loss can sometimes be only 50% as rapid as other programs which are destroying muscle and fat. The problem is that muscle is hard to get back, and any drop in muscle mass results in a lower metabolic rate, leaving the dieter more likely to gain back the weight, but this time only in body fat. Many lectins can amplify the effects of auto-immune disease, such as thyroiditis, rheumatoid arthritis, schleroderma, bromylagia and pemphigus. Research shows that some of the lectins that can cause this may actually be manufactured by the body itself (serum lectins). By acting as sacricial molecules, Deect ® can block this action. Many people with ‘food sensitivities’ or ‘leaky gut’ have a phenomena called ‘active endocytosis’ where prior lectin damage results in an intestinal absorption surface that actively scoops up macromolecules. Because these larger molecules are very antigenic, they tend to increase local inammation and thus increase the leaky gut. Again, by acting like ‘sacrical molecules Deect ® can block this, while also inhibiting bacterial D’ADAMO  NAP PROFESSIONAL SERVICES Deect ® (ABO Specifc Lectin Blocker Formula)

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120 VeggieCaps per bottle.

Suggested retail price: $34.95Typically, lectins can bind to many of the carbohydrate antigensfound in the gut and immune system, causing a variety of health

problems. This is usually accomplished by direct agglutination of 

the target cells. Lectins can occur in very common foods in the

diet, and the majority is specic for the carbohydrates of the ABOblood typing system.

Clinical Indications• Intestinal dysbiosis

• Bowel hyperpermiability

• Immune dysfunction

• Food sensitivities and systemic inammation• Metabolic Syndrome

• Carbohydrate intolerant individuals who typically gainweight on high carbohydrate diets.

In one study, the edible parts of 29 of 88 foods tested, includingcommon salad ingredients, fresh fruits, roasted nuts, and processed

cereals were found to possess signicant lectin-like activity as

assessed by hemagglutination and bacterial agglutination assays.

Several common lectins, in particular, wheat germ agglutinin, are

known to bind to the insulin receptor and mimick the hormonal

effects of insulin on adipose tissue, an under-appreciated actionwhich can account for why individuals on high carbohydrate diets

often have difculty contolling their weight. Thus, lectin blockingis a safe and rational method for enhancing weight loss.

In the words of one lectin researcher:

“Most lectins in our diet are resistant to breakdown during gut passage and 

are bound and endocytosed by epithelial cells. These lectins are powerful

exogenous growth factors for the small intestine, can induce dramatic

shifts in its bacterial ora and interfere with its hormone secretion. In

addition, lectins that are transported across the gut wall into the systemic

circulation can modulate the body’s hormone balance, metabolism and 

health. Although these physiological effects are mediated or reinforced by 

immune responses, they are primarily the result of the specic chemical

reactivity of lectins with cell surface receptors of the gut.”

Actions and IndicationsThe Deect® formula provides a source of free blocking aminosugars which bind and block lectins before they can attach to

the cells.

Since each blood type is succeptible to lectins with different

carbohydrate specicities, Dr. D’Adamo designed formulas to

block lectins by using mono and polysaccharides specic for 

each blood type.

The amino sugars in Deect®

encourage healthy bowel ora,although they do not provide a source of ora themselves.These same amino sugars are healthy enhancers of joint gliding

surface and synovia as well.

One way this repair mechanism works is by ‘prying off’

lectins which have already adhered to cellular receptors, such

as insulin. Since insulin blockage by dietary lectins has beenlinked to both insulin resistance and obesity, using Deect® can

help accelerate weight reduction in diet-compliant individuals

by speeding up the time it takes for the regeneration of new

insulin receptors or the ‘cleansing’ of the old ones.

This can take upwards of one year in some individuals who

just follow the diet, and explains why some dieters do not see

weight loss in the early stages of the program. It is because of this ‘lectin-locking’ function that many other diets (which do

have accelerated weight loss in their early stages) cause their 

followers to lose muscle mass and fat -when what we want isto lose only the fat. If the weight loss in the Blood Type Diet

is occasionally slow, at least it is healthy: Losing only body fat

means that a person’s weight loss can sometimes be only 50%

as rapid as other programs which are destroying muscle and fat.The problem is that muscle is hard to get back, and any drop

in muscle mass results in a lower metabolic rate, leaving the

dieter more likely to gain back the weight, but this time only

in body fat.

Many lectins can amplify the effects of auto-immune disease,

such as thyroiditis, rheumatoid arthritis, schleroderma,bromylagia and pemphigus. Research shows that some of the

lectins that can cause this may actually be manufactured by the

body itself (serum lectins). By acting as sacricial molecules,

Deect® can block this action.

Many people with ‘food sensitivities’ or ‘leaky gut’ have a

phenomena called ‘active endocytosis’ where prior lectindamage results in an intestinal absorption surface that actively

scoops up macromolecules. Because these larger molecules are

very antigenic, they tend to increase local inammation and

thus increase the leaky gut. Again, by acting like ‘sacricalmolecules’ Deect® can block this, while also inhibiting bacterial

D’ADAMO NAP PROFESSIONAL SERVICES

Deect® (ABO Specifc Lectin Blocker Formula)

8/7/2019 Deflect SpecSheet

http://slidepdf.com/reader/full/deflect-specsheet 2/4

adhesion to the gut as well (bacteria use their own lectins to attachto the intestines) a secondary cause of leaky gut. The amino sugars

in Deect® can also help prevent re-infection by H. pylori and

many gram-negative bacteria which cause bladder infections, by

ooding their own lectin receptors, thereby preventing adhesion,the rst step needed for infection.

The amino sugars in Deect® encourage healthy bowel ora,although they do not provide a source of ora themselves. These

same amino sugars are healthy enhancers of joint gliding surface

and synovia as well.

Synergistic Products

• Redoxa, Quercetin (Leaky gut support in all types)

• Itaru’s Tea (Weight management in all types)

• Polyora O, Polyora A, Polyora B, Polyora AB (Dysbiosis

in all types)

• Bromelain (Joint dysfunction in all types)

Dosage• Weight management and anti-lectin support: 1-2 capsules

with meals

• Other conditions: 1-2 capsule twice daily away from meals

See Also• Boyd’s Report of Lectin Specicity

• Dietary lectins are metabolic signals for the gut and modulate

immune and hormone functions

• Dietary lectins can induce in vitro release of IL-4 and IL-13

from human basophils

• Glycosylation

• Lectins, Mitogen and Blastogenic Effects

• Lectins, Resistance to Degradation

• Lectins in the United States Diet

• Microvilli

• Mitogen

• Mitosis

• Mucosa

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26. Falth-Magnusson K, et al. Elevated levels of serum antibodies to the lectinwheat germ agglutinin in celiac children lend support to the gluten-lectintheory of celiac disease. Pediatr Allergy Immunol. 1995 May;6 (2):98-102.

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37. Greer F, Pusztai A Toxicity of kidney bean (Phaseolus vulgaris) in rats:changes in intestinal permeability. Digestion 1985;32(1):42-6

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41. Henney L, Ahmed EM, George DE, Kao KJ, Sitren HS Tolerance to long-term feeding of isolated peanut lectin in the rat: evidence for a trophic effecton the small intestines J Nutr Sci Vitaminol (Tokyo) 1990 Dec;36(6):599-607

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copyright © 2010, North American Pharmacal, Inc. All Rights Reserved.

These statements have not been evaluated by the FDA (U.S. Food & Drug Administration).

Our products are not intended to diagnose, cure or prevent any disease. If a condition persists, please contact your physician.

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