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DEPARTMENT OF BIOCHEMISTRY BHARATHIDASAN UNIVERSITY Tiruchirappalli- 620 024, India PROFILE

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DEPARTMENT OF BIOCHEMISTRY

BHARATHIDASAN UNIVERSITY Tiruchirappalli- 620 024, India

PROFILE

2

DST-FIST (Level I)

RUSA

DST- PURSE

National Recognitions

3

Dr. Vasanthi Nachiappan

Professor and Head

Dr. Anusuyadevi Jayachandran

Assistant Professor

Dr. C. Prahalathan

Assistant Professor

Dr. V. Ravikumar

Assistant Professor

Dr. A. Antony Joseph Velanganni

Assistant Professor

Dr. A.N. Dhina

Guest Lecturer

Faculty Members

4

Preface

The Department of Biochemistry was established in the year 2005. Department offers a two-year

M.Sc Progarm in Biochemsitry, one-year M.Phil Program and Ph.D program in various

specializations. We also actively involved in teaching M.Sc Life Science Students and handle

courses related to Biochemistry. Biochemistry is an integrated subject fulfilling the need for basic as

well as applied aspects of biology and prepares the students to become entrepreneur, teacher,

researcher, or to fit into equipping themselves to the future needs along with the basic and applied

knowledge of modern biology. Keeping in view the updates and trends among International Institutes

around the world, we frequently update the syllabus inculcating international standards and

modernize the curriculum that will benefit our younger generation and qualify them to contribute to

the welfare of the society.

All the faculty members of Deparment of Biochemistry have got their research specialization from

various leading laboratories around the world and got intense training during their post doctoral

experience. The main areas of research includes, Membrane Biochemistry, Cancer Biology,

Neurogerontology, Reproductive Biology etc., We have produced more than 20 PhD‟s who have got

placed as scientist, post doctoral fellows in various leading International Institutes like in USA,

Korea, Sweden. Within the short span time, the Department has grown into a vibrant academic

department and research centre in Biochemistry, where we have made great stride in higher

education, research and extension activities in the area of specialization. The Department was

recognized for DST-FIST Program in the year 2012. The department has generated funds worth five

plus crores for Research and Infrastructure from various funding agencies like CSIR, NFMP, DST,

DBT, ICMR, UGC etc., To add on to the credentials, more high impact factor publications has been

made in well reputed Journals and published many book chapters in the core area of research. The

department has hosted many national level conferences and workshops benefiting students.

Professor and Head

5

Objectives:

To conceive and conduct programmes in Biochemistry at Post-graduate and M.Phil. levels to

train manpower for the Academic and Research Institutions

To carry out Basic, Applied and Advanced Research in various fields of Biochemistry

Vision and Mission

Create a suitable ambience for students & teachers to

Promote higher learning

Solve vital problems in Biology & Medicine

To promote higher learning on par with international standards.

To solve vital problems in biology and medicine for welfare of humanity.

To implement quality work to enable scholars to do imperative research.

6

Faculty I

Area of Research/Specialization:

Our lab focuses on the role of transcription factors and their involvement in lipids during adverse conditions. Environmental pollutants and heavy metals have an impact on yeast phospholipids. Understanding the lipid related metabolic pathways during such adverse conditions may provide knowledge for developing novel therapeutics for these toxicity related disorders. We use combination of genetics and molecular approaches to implicate the role of genes and proteins that regulate lipid metabolism under pathological conditions using Saccharomyces cerevisiae and human cell line as model system.

Dr. Vasanthi Nachiappan

Achievements made in Teaching/Research/Extension Professor & Head

No. of Research Publications : 45

No. of papers presented in Conferences : 26

h-index : 14

i-10 index : 17

Total Citations : 586

Patents Granted/Filed : --

Products Developed : --

Projects Completed/Ongoing : 3/1

Consultancies Completed/Ongoing : --

Awards and Recognitions Indian Association of Biomedical Scientists (Iabms) Award For Dr. C. R. Krishnamurthy

Memorial Award Nov 4th 2016

Post Doctoral Training at USA for about six years (1989 to 1995)

Product Development in Collaboration with Indian Institute of Science for about eight years.

Research Group Members C. Ravi

R. Gowsalya

N. Bhanupriya

M. Arul

S. Vennila

M. Subitha

Past Members 1. Dr. P. Vijayaraj 5. Dr. Karpagam 9. Dr. C. Sivaprakasam 13. Dr. R. Vijayakumar

2. Dr. K.

Muthukumar 6. Dr. S. Shanmughapriya 10. Dr. S. Rajakumar 14. Dr. Abhishek Raj

3. Dr. J. Sabatirajan 7. Dr. K. Selvaraju 11. Dr. D. Kalyani 4. Dr. K. Jyothi 8. Dr. L. Vishnuvarthini 12. Dr. A. William

James

7

Faculty II

Area of Research/Specialization:

Molecular Neurogerontology

Dr. M. Anusuyadevi Jayachandran

Achievements made in Teaching/Research/Extension Assistant Professor No. of Research Publications : 25

No. of papers presented in Conferences : 34

h-index : 14

i-10 index : 14

Total Citations : 804

Patents Granted/Filed : --

Products Developed : --

Projects Completed/Ongoing : 4/1

Consultancies Completed/Ongoing : --

Awards and Recognitions Young Faculty Award, VIFFA 2015

Young scientist award – DST

Young Investigator award – DBT

Post-doctoral Scholar, Medical University of South Carolina, Dept. of Physiology and

Neurosciences, U.S.A. (2007 to 2008)

Research Group Members Mrs. Meher Nisha

Ms. M. Suhadha Parveen

Mr. Syed Aasish Roshan

Past Members

1. P.Premkumar

2. M.Sathya

3. C.Karthick

4. P.Moorthi

5. S.Periyasamy

6. ML. Mini

8

Faculty III

Area of Research/Specialization:

Molecular Endocrinology

Dr. C. Prahalthan

Achievements made in Teaching/Research/Extension Assistant Professor

No. of Research Publications : 20

No. of papers presented in Conferences : 17

h-index : 13

i-10 index : 13

Total Citations : 705

Patents Granted/Filed : --

Products Developed : --

Projects Completed/Ongoing : 4/1

Consultancies Completed/Ongoing : --

Awards and Recognitions

Young Investigator Award – DBT

Young Scientist Award – SERB

Receipient of American Heart Association Postdoctoral Fellowship, USA.

Postdoctoral Fellowship from American Diabetes Association, USA.

Research Group Members

K. Arun

P. Anto Jenifer

M. Lezy Flora

Past Members

1. Dr. S. Mohanraj

2. Dr. B. Sivasangari

3. Dr. R. Balamurugan

9

Faculty IV

Area of Research/Specialization:

Epigenetic Regulation in Lung Cancer

Dr. V. Ravikumar

Achievements made in Teaching/Research/Extension Assistant Professor No. of Research Publications : 40

No. of papers presented in Conferences : 19

h-index : 15

i-10 index : 12

Total Citations : 569

Patents Granted/Filed : --

Products Developed : --

Projects Completed/Ongoing : 2/1

Consultancies Completed/Ongoing : --

Awards and Recognitions Young Scientist awarded - SERB

Postdoctoral training from Kyung Hee University, Korea.

Project Fellow awarded by University Grants Commission programme of Institute for Herbal

Sciences, Govt. of India.

Scientist (R&D) at Biosewoom Inc., Institute of Bioscience and Biotechnology, Seoul,

Korea. (Apr 2008 – Sep 2008).

Postdoctoral Research Fellowship awarded by Brain Korea 21 scheme, Government of

Korea (2006- 2008).

Research Group Members

K. Varunkumar

C. Anusha

A. Kalairasi

K. Sarvanan

Dindi Uma Maheswara Rao

S. Prabhu

Past Members 1. Dr. S. Karthik

2. Dr. R. Sankar

10

Faculty V

Area of Research/Specialization:

Molecular Oncology

Dr. A. Antony Joseph Velanganni

Achievements made in Teaching/Research/Extension Assistant Professor

No. of Research Publications : 12

No. of papers presented in Conferences : 1

h-index : 5

i-10 index : 4

Total Citations : 83

Patents Granted/Filed : --

Products Developed : --

Projects Completed/Ongoing : 3/1

Consultancies Completed/Ongoing : --

Awards and Recognitions

Young Scientist awarded - DBT

Research Group Members

M. Rajesh Kannan

J. Sridharan

K. Lakshmi Priya

N. Anantha Lakshmi

K. Mahesh

U. Devan

G. Nithya

Past Members 1. --

11

12

S. No. Name Reg. No. Fellowship

1. Karthik S 6354 UGC – Project Fellow

2. Sankar R 44356 DST INSPIRE – SRF

3. Mohanraj S 4818 ICMR - JRF

4. Premkumar P 6403 DST – Project Fellow

5. Sivasangari B 4933 DBT – JRF

6. Sathya M 39336 UGC – Project Assistant

7. Karthick C 5195 CSIR – SRF

8. Balamurugan R 33504 UGC – Project Fellow

9. Selvaraju K 22214 CSIR - SRF

10. Varunkumar K 45376

DST – JRF

ICMR - SRF

11. Anusha C 30014 URF – BDU

12. William James 42467 DST – PURSE

13. Sivapraksam 43854 NMPB - JRF

14. Vijayakumar R 42234 NMPB – SRF

CSIR - SRF

15. Lakshmi Priya K 45375 DST – INSPIRE - SRF

16. Arun K 7905 URF – BDU

ICMR - SRF

17. Sridharan J 32851 URF – BDU

18. Periyasamy S 47364 URF – BDU

19. Uma Maheswara Rao D 34407 UGC – RGNF – SRF

20. Saravanan K 34406 DST – SERB – JRF

21. Anantha Lakshmi N 7705 DST – (WOS – A) – PI

22. Mahesh Kumar K 7941 DBT – JRF

23. Palanimuthu DST – Post –Doc

24. Bhanupriya N 45145 DST – INSPIRE – JRF

25. Vennila S 29336 DST – WOS-A – SRF

26. Ravi C 32367 SERB – JRF

27. Roseline M 7868 URF – BDU

28. Nithya G 14727 URF – BDU

29. Subitha M 5486 URF - BDU

30. Prabhu S 25991 DST – PURSE II - JRF

31. Suhadha Parveen 25862 LADY TATA – JRF

32. Roshan 003280 DBT- JRF

Details of Fellowships being availed by the

Research Scholars/Project Staff

13

Citations

14

1. Ravikumar V., Sankar. R. (2017), Preparation of Histone Deacetylase Inhibitor

Vorinostat –Loaded Poly d, l-Lactide-co-Glycolide Polymeric Nanoparticles by

Nanoprecipitation Method. In: Kramer O. (Eds.) HDAC/HAT Function Assessment and

Inhibitor Development. Methods in Molecular Biology, Vol 1510. Hanuma Press,

NewYork, NY, pp 399-403. ISBN: 978-1-4939-6525-0.

2. R Vilwanathan, A Chidambaram and R Kumar Chidambaram (2018), Pharmocoepigenetics:

Novel mechanistic insights in drug discovery and development targeting chromatin

modifying enzymes. In: Ramon Cacabelos (Eds). Pharmocoepigenetics, Vol 10. Academic

Press, Elsevier, USA, ISBN: 978-0-12-18139394.

3. Divya Dasagrandhi, Arul Salomee Kamalabai R, Anusuyadevi Muthuswamy, Jayachandran

Kesavan Swaminathan. (2018) Construction and Analysis of Protein-Protein Interaction

Network: Role in Identification of Key Signaling Molecules Involved in a Disease

Pathway. IGI Global Publishers.

4. Senthilkumar B, Senbagam B, Prahalathan C, Anbarasu K. Gateways of Pathogenic

Bacterial Entry into Host Cells- Salmonella in a book ‘Pocket Guide to Bacterial

Infections’ which is part of ‘Pocket Guide to Biomedical Scientists‟ by CRC Press. 2018:

59-71

Conferences/Workshops/Seminars Organized

S. No. Conferences/Workshops/Seminars Period

1.

Evolutionary Trends in Biochemistry and Molecular

Biology – BIOTRENDS 2012 and 1st Annual Seminar on

Awareness of Alzheimers‟s Disease – ALZINFO 2012

20th

& 21st Sep,

2012

2. National Conference on Challenges and future prospects of

Applied research in Life Sciences 6

th Feb, 2015

3. Lecture Workshop on Hands on Training in Cell and

Molecular Biology Techniques

14th

– 27th

March

2018

Book Chapters (2013-14 to 2017-18)

15

1. M. Sc. Biochemistry

2. M. Phil.Biochemistry

3. Ph. D. Biochemistry

M. Sc. Biochemistry

Program objectives

The objectives of M. Sc. Biochemistry programme are:

PG Granduands are Professionally Competent with characteristic Knowledge-bank, Skill-set,

Mind-set and Pragmatic Wisdom in their chosen fields.

PG Granduands demonstrate the desired sense of being Seasoned and exhibit unequivocal

Spiritedness with excellent qualities of productive contribution to society and nation in the arena

Science and Technology.

PG Graduands are mentored such that they exert Leadership Latitude in their chosen fields with

commitment to novelty and distinction.

PG Graduants are directed in understanding of ethical principles and responsibilities, moral and social

values in day-to-day life thereby attaining Cultural and Civilized personality.

PG Graduants of are able to Collate information from different kinds of sources and gain a coherent

understanding of the subject.

Eligibility

A candidate who has passed B.Sc. Degree Examination of Bharathidasan University

with Biochemistry/ Chemistry / Zoology /Botany / Nutrition & Dietetics / Food Science/

Microbiology / Biotechnology as the Major subject or an examination of any other

University accepted by the Syndicate of Bharathidasan University as equivalent to the B.Sc.

degree examination of Bharathidasan University may be permitted to qualify for the M.Sc.

Degree in Biochemistry by undergoing courses and appear for the examinations of this

Department. A candidate for admission to the programme shall not be more than 25 years of

age as on 1st July of the year of admission.

Selection Procedure

Selection will be made on the basis of merit list prepared from the Entrance exam and semester

marks secured in UG degree.

M. Phil. Biochemistry

Program objectives

The objectives of M. Phil. Biochemistry programme are:

Programmes offered

16

To give the student adequate background for advanced research.

The M.Phil. Degree shall have the status of an intermediate degree between the Post-graduate

degree and the Doctoral Degree.

It will have both research and course component.

Eligibility

Master‟s degree in relevant subject with a first class or minimum 60% marks (CGPA 6.5

on a 10 – point scale).

Selection Procedure

Applications will be invited by open advertisement in all leading newspapers / local

announcement for all categories of candidates Internal full-time Candidates: A candidate

who wishes to work for M.Phil. degree on full time (including project staff working in

sponsored projects being carried out at the institute) should apply in the prescribed form on

or before due dates to be announced normally once every year.

Out of the applications received, the Schools will short-list the candidates to be called for

written test / interview to be conducted at the institute on a pre-announced date.

Selection will be based on the overall merit index of the candidate which will be arrived at

by taking into account the candidate‟s performance in the previous university examinations

at Bachelor‟s and Master‟s level and the performance in the written test and / the interview.

The weightages for arriving at the overall merit index will be as follows: Bachelor‟s degree

– 20 % Master‟s degree – 20 % Written test and / Interview – 60 %

S. No. Reg. No. Name Exam(s) Qualified

1. 34034 D. Uma Maheswara Rao CSIR-UGC NET LS

Awards Received by students/scholars Year Name of the Awarded

Students

National Awards

Name of the Award Awarding Institution

2010 R. Sankar DST -INSPIRE DST

2011 C. Kaarthick CSIR – SRF CSIR

2012 K. Lakshmi Priya DST -INSPIRE DST

2013 S. Rajakumar Rajiv Gandhi Fellowship UGC

2014 N. Anantha Lakshmi DST – WOS- A DST

2015 D. Uma Maheswara rao Rajiv Gandhi Fellowship UGC

2015 B. Sivasangari Best Paper Award in 6th

World Congress of Diabetes

Grand Chola Convention

Centre, Chennai.

2015 K. Arun Best Poster awaid in 6th

World Congress of Diabetes

Grand Chola Convention

Centre, Chennai.

2015 S. Mohanraj Best Paper Award in

National Seminar.

Central University of

Tamil Nadu, Thiruvarur.

2015 Nishanthini Best Poster awaid in

Bangalore India Bio 2015

Bangalore.

Students’ achievements (2013-14 to 2017-18)

17

2016 S. Vennila DST – WOS- A DST

2018 K. Arun ICMR – SRF ICMR

2018 K. Varunkumar ICMR – SRF ICMR

Foreign PDF received by scholars

Name of the scholar Awarding institution

Dr. K. Muthukumar Post Doctoral Fellow, National Jewish Health, Dencer –

CO, USA.

Dr. J. Sabarirajan Post Doctoral Fellow, National Jewish Health, Dencer –

CO, USA.

Dr. S. Shanmughapriya Post Doctoral Fellow, Temple University School of

Philadelphia, PA 19140, USA.

Dr. K. Selvaraju Post Doctoral Fellow, John Hopkins University, USA

Dr. S. Karthik Prinicipal Research Scientist/ Engineer, Department of

Medicine and health, Linkoping, Sweden.

Dr. R. Sankar Post Doctoral Researcher, Food and animal Health

Research Program, The Ohio State University, Ohio

USA.

Dr. S. Mohanraj Post Doctoral Fellow, John Hopkins University, USA

Dr. C. Sivaprakasam Post Doctoral Fellow, Department of Pathology and

Laboratory Medicine, University of Cincinati, USA

Dr. A. William James Post Doctoral Fellow, Diabetes and Obesity Research

Center, Winthrop University Hospital, USA.

Dr. S. Rajakumar Post Doctoral Fellow, Department of Pediatrics,

University of Alberta, Canada

Dr. P. Moorthi Post Doctoral Fellow, Department of Neurobiology,

University of Chicago, USA

Dr. C. Karthick Post Doctoral Fellow, Temple University School of

Philadelphia, PA 19140, USA.

Dr. M. Sathya Post Doctoral Researcher, Department of Neurobiology,

Care Sciences and Society – NVS, Karolinska Institutet,

Sweden.

Dr. R. Balamurugan Post Doctoral Fellow, School of Medicine, Vanderbilt

University, USA.

Abhishek Raj Post Doctoral Fellow,

R. Vijayakumar Post Doctoral Fellow,

C Karthick Post Doctoral Fellow, Temple University, USA

Moorthi Ponnusamy Post Doctoral Fellow, University of Chicago, USA

Premkumar P Post Doctoral Fellow, National Brain Research Institute,

India

Sathya M Post Doctoral Fellow, Karolinska University, Sweden

18

Ph. D. Awardees M. Sc. Gold Medalists

Name Year of passing Name Year of passing

P. Vijayaraj 2011 Shobana Pandian 2011

N. Karpagam 2011 Ajitha 2012

K. Muthukumar 2011 P Kirijayini 2013

J. Sabarirajan 2012

Uma Maheshwari

Nallal 2015

K. Jyothi 2013 Silpa Sasi 2016

S. Shanmughapriya 2013

D. Kalyani 2014

K. Selvaraju 2014

S. Karthik 2014

R. Sankar 2015

V. Vishnu varthini 2015

C. Sivaprakasam 2015

S. Mohanraj 2015

B. Sivasangari 2016

S. Rajakumar 2016

A. William James 2017

R. Balamurugan 2017

P. Premkumar 2017

M. Sathya 2017

P. Moorthi 2018

Abhishek Raj 2018

C. Karthick 2018

R. Vijayakumar 2018

19

Real Time PCR

-80 Deg Deep Freezer

UV Visible Spectrophotometer

CO2 Incubator

Laminar Air Flow Cold Room Facility

Facilities

20

Computer Facility (DST-FIST) Department Library

National Conference “Evolutionary trends in

Biochemistry and molecular biology(“BIOTRENDZ-2012”) &I Annual seminar

on Alzheimer’s disease(ALZINFO-2012)”

National Conference on Challenges and future prospects of applied research in life

science (NCCFPARLS – 2016)

Clean and Green Initiative - 2018

World Food Day – October 2018

Conferences, Seminars and Workshop Organised

21

Workshop on “Hands on Training Cell and Molecular Biology Tachniques – March „2018”

Screening of Dementia subjects among Aged

population of Dharmapuri District

Biochallenger‟s Club

Departmental Activities

22

Dr. Vasanthi Nachiappan Professor and Head Department of Biochemistry Bharathidasan University Tiruchirappalli -620 024 Tamil Nadu, India Tel: +91 431 –2407071 Ext 631 Fax:+91 431- 2407045 E-Mail: [email protected] www.bdu.ac.in

Contact us

23

Research & Consultancy Projects

Completed Projects

S.

No.

Principal

Investigator

Project Title Period Funding

Agency

Amount

₹ (in

lakhs) From To

1. Dr. Vasanthi

Nachiappan

Remodeling of fatty acid in

phosphatidyl choline rat liver as a

model system

2008 2011 UGC 10.89

2. Dr. Vasanthi

Nachiappan

Endoplasmic reticulum (ER)

stress induced autophagy in

Saccharomyces cerevisiae and the

implication in Phospholipid.

2012 2015 CSIR 22.92

3. Dr. Vasanthi

Nachiappan

Characterization of active

principle from Cassia auriculata

as a potential drug for

hyperlipidemia and cardiovascular

disease

2013 2017 NMPB 23.52

4. Dr. M.

Anusuyadevi

Jayachandran

Identification of the Intracellular

localization of α, β and γ secretase

and APP cleavage pattern in

young and aged rat brain region:

an understanding towards the

underlying mechanism behind AD

pathology.

2012 2015 UGC 13.48

5. Dr. M.

Anusuyadevi

Jayachandran

Hyperinsulinemia influences

autophagy and mitochondrial

biogenesis: A possible mechanism

of neuronal ageing.

2013 2016 ICMR 50

6. Dr. C.

Prahalathan

Evaluation of the Effect of Acute

Inflammation on Histone H3

Modifications in Rat Testis and

Its Implications in Testicular

Steroidogenesis

2011 2014 DBT 21.63

7. Dr. C.

Prahalathan

A Study on Proinflammatory

Cytokines Mediated Histone H3

Modifications in R2C Leydig

Cells and Its Implications in

Regulation of Testicular

Steroidogenesis

2011 2014 ICMR 20.15

8. Dr. C.

Prahalathan

Evaluation of the Effect of Acute

Inflammation on Histone H3

Modifications in Rat Pancreas and

Its Implications in Insulin Gene

Transcription

2011 2014 UGC 13.17

9. Dr. C.

Prahalathan

Role of Class II Histone

Deacetylases in Regulation of

Insulin Gene Transcription

2012 2015 DST 16.70

10. Dr. V. Nano encapsulation of

Suberoylanilide hydroxamic acid 2011 2014 UGC 11.14

24

Ravikumar (SAHA): an attempt to improve

anticancer activity in non-small

cell lung cancer cell lines.

11. Dr. V.

Ravikumar

Synergistic Interaction Of The

Histone Deacetylase Inhibitor

With The Proteasome Inhibitor In

Lung Cancer.

2012 2015 DST 22.75

12. Dr. A.

Antony

Joseph

Velanganni

Molecular characterization of

Constitutive and Consensus

miRNA Expression Profiles in

NCI-60 Panel of Human Cancer

Cell Lines

2012 2015 UGC 13.92

13. Dr. A.

Antony

Joseph

Velanganni

Exploration of hTERT gene

inhibition in cervical cancer cells

by nanoencapsulated hTERT-

siRNA

2014 2017 DST-

(WOS-

A)

24.13

14. Dr. A.

Antony

Joseph

Velanganni

RNAi mediated Functional

Analysis of RNA induced

Silencing Complex (RISC) and its

Component AEG-1 that induce

the Expression of Transcription

Factor LSF in Hepatocellular

Carcinoma

2015 2018 DBT 25.00

25

Ongoing Projects

S.

No.

Principal

Investigator

Project Title Period Funding

Agency

Amount

₹ (in

lakhs)

From To

1. Dr. Vasanthi

Nachiappan

High throughput screening &

molecular analysis of GCR1

transcription factor and its impact on

the binding motif of OPI3 promoter

in Saccharomyces cerevisae

2017 2020 SERB 47.92

2. Dr. M.

Anusuyadevi

Jayachandran

Assessment of the effect of aspirin

treatment on neural stem cells and

the regulation of hippocampal

neurogenesis in the adult brain of the

experimental rodents: A non-invasive

attempt for the brain regeneration

2017 2020 SERB 52.00

3. Dr. C.

Prahalathan

Elucidation of the role of SIRT4 in

testicular steroidogenesis 2018 2021 SERB 38.20

4. Dr. V.

Ravikumar

Investigation on acetylation

dependent activation of Notch

signaling pathway by HDAC

inhibitors - A possible mechanism

for drug resistance and survival upon

HDAC inhibition therapy in NSCLC

cell lines

2016 2019 SERB 28.99

5. Dr. A.

Antony

Joseph

Velanganni

Social Support and Reproductive

Autonomy of Visually Challenged

Women in the Rural Districts of

Tamil Nadu

2017 2019 ICMR-

ICSSR

13.75

26

Collaborative Project

S.

No

Agency Period Project Title Budget

(Rs. In

lakhs) From To

1 NMPB 2012 2015 Characerization Of Active Principles From

Cassia Auriculata As A Potential Drug For

Hyperlilpidemia And Cardiovascular Diseases

23.52

2 CSIR 2012 2015 Endoplasmic reticulum stress induced

autophagy in Saccharomyces cerevisiae and

the implications in phospholipids

22.92

3 DBT 2012 2015

Studies on Potential Oncogenic Role of the

Transcription Factor Nsep1 Association with

the Overexpressed Rps27a in Human

Hepatocellular Carcinoma (HCC)

27.07

4 CSIR 2012 2015 Novel MASP-2 inhibitor from Indian

medicinal plants for protection against

myocardial infraction

16.00

5 DBT 2012 2016 Structural Exploration of Recombinant Mouse

Seminal Vesicle Spink-3 Receptor on Sperm 29.87

6 SERB 2018 2021

Assessment of the effect of aspirin treatment

on neural stem cells and the regulation of

hippocampal neurogenesis in the adult brain

of the experimental rodents: A non-invasive

attempt for the brain regeneration

52.00

.

27

List of Research Publications since 2013 to 2018

1. Anandhi R, Annadurai T, Anitha TS, Muralidharan AR, Najmunnisha K, Nachiappan V,

Thomas PA, Geraldine (2013). Antihypercholesterolemic and antioxidative effects of an extract

of the oyster mushroom, Pleurotus ostreatus, and its major constituent, chrysin, in Triton WR-

1339-induced hypercholesterolemic rats. J Physiol Biochem. 69(2):313-23. doi: 10.1007/s13105-

012-0215-6.

2. Shanmughapriya S, Nachiappan V, Natarajaseenivasan K (2013) BRCA1 and BRCA2

mutations in the ovarian cancer population across race and ethnicity: special reference to

Asia. Oncology. 84(4):226-32. doi: 10.1159/000346593.

3. Muthukumar K, Nachiappan V. (2013) Phosphatidylethanolamine from phosphatidylserine

decarboxylase2 is essential for autophagy under cadmium stress in Saccharomyces

cerevisiae. Cell Biochem Biophys. 67(3):1353-63. doi: 10.1007/s12013-013-9667-8.

4. Muthusamy K, Singh KhD, Chinnasamy S, Nagamani S, Krishnasamy G, Thiyagarajan C,

Premkumar P, Anusuyadevi M. High throughput virtual screening and E-pharmacophore

filtering in the discovery of new BACE-1 inhibitors. Interdiscip Sci. 2013 Jun;5(2):119-26.

5. Origanum vulgare mediated biosynthesis of silver nanoparticles for its antibacterial and

anticancer activity. Sankar R, Karthik A, Prabu A, Karthik S, Shivashangari KS, Ravikumar V,

Colloids and Surfaces B: Biointerfaces. 108:80-84, 2013.

6. Vishnu Varthini L Selvaraju K, Srinivasan M, Nachiappan V. (2014) ROG1 encodes a

monoacylglycerol lipase in Saccharomyces cerevisiae. FEBS Lett. pii: S0014-5793(14)00824-2.

doi: 10.1016/j.febslet.2014.11.019.

7. Selvaraju K, Rajakumar S, Nachiappan V. (2014) Identification of a phospholipase B encoded

by the LPL1 gene in Saccharomyces cerevisiae. Biochim Biophys Acta. 1841(10):1383-1392.

doi: 10.1016/j.bbalip.2014.06.013

8. Vijayaraj P, Sivaprakasam C, Varthini LV, Sarkar M, Nachiappan V. (2014) In vitro exposure

of tobacco specific nitrosamines decreases the rat lung phospholipids by enhanced

phospholipase A2 activity. Toxicol In Vitro. 28(6):1097-105. doi: 10.1016/j.tiv.2014.05.001.

9. Kalyani D, Jyothi K, Sivaprakasam C, Nachiappan V. (2014) Spectroscopic and molecular

modeling studies on the interactions of N-Methylformamide with superoxide

dismutase. Spectrochim Acta A Mol Biomol Spectrosc. 124:148-52. doi:

10.1016/j.saa.2014.01.013

10. James AW, Nachiappan V. (2014) Phosphate transporter mediated lipid accumulation in

Saccharomyces cerevisiae under phosphate starvation conditions.Bioresour Technol. 151:100-5.

doi: 10.1016/j.biortech.2013.10.054

11. Kannan A, Prahalathan C. Effect of hyperglycaemia on the expression of aquaporins in

diabetic rat testis. Diabetologia. 2014:57;s535-36.

28

12. Sadasivam M, Ramatchandirin B, Balakrishnan S, Selvaraj K, Prahalathan C. The role of

phosphoenolpyruvate carboxykinase in neuronal steroidogenesis under acute inflammation.

Gene. 2014;552:249-54.

13. Balakrishnan S, Sadasivam M, Kannan A, Selvam AP, Prahalathan C. Glucose modulates Pax6

expression through the JNK/p38 MAP kinase pathway in pancreatic beta-cells. Life Sci.

2014;109:1-7.

14. Sadasivam M, Ramatchandirin B, Ayyanar A, Prahalathan C. Bacterial lipopolysaccharide

differently modulates steroidogenic enzymes gene expressions in brain and testis in rats.

Neurosci Res. 2014;83:81-8.

15. Biocompatibility and biodistribution of suberoylanilide hydroxamic acid loaded poly (DL-

lactide-co-glycolide) nanoparticles for targeted drug delivery in cancer. Sankar R, Ravikumar

V. Biomedicine & Pharmacotherapy 68 (2014) 865–871, 2014.

16. Growth inhibition of bloom forming cyanobacterium Microcystis aeruginosa by green route

fabricated copper oxide nanoparticles. Sankar R, Balaji Prasath B, Nandakumar R, Santhanam P,

Shivashangari KS, Ravikumar V, Journal of Environmental and Pollution Research DOI

10.1007/s11356-014-3362-1, 2014.

17. Anticancer activity of Ficus religiosa engineered copper oxide nanoparticles. Sankar R,

Maheswari R, Karthik S, Shivashangari KS, Ravikumar V, Materials Science and Engineering

C 44 (2014) 234–239, 2014.

18. Wound healing activity of Origanum vulgare engineered titanium dioxide nanoparticles in

wistar -albino rats. Sankar R, Dhivya R, Shivashangari KS, Ravikumar V, J Mater Sci Mater

Med. 25, 1701-1708, 2014.

19. Green synthesis of colloidal copper oxide nanoparticles using Carica papaya and its application

in photocatalytic dye degradation. Sankar R, Manikandan P, Malarvizhi V, Fathima T,

Shivashangari KS, RavikumarV, Spectrochim Acta A Mol Biomol Spectrosc. 121:746-50,

2014.

20. Anbazahan SM, Shanthi Mari LS, Yogeshwari G, Jagruthi C, Thirumurugan R, Arockiaraj J, A.

Antony Joseph Velanganni, Krishnamoorthy P, Balasundaram C, Harikrishnan R (2014).

Immune Response and Disease Resistance of Carotenoids Supplementation Diet in Cyprinus

Carpio against Aeromonas Hydrophila. Fish Shellfish Immunol. Jun 20;40(1):9-13.

21. Sivaprakasam C, Nachiappan V. (2015) Modulatory effect of cadmium on the expression of

phospholipase A2 and proinflammatory genes in rat testis. Environ Toxicol. doi:

10.1002/tox.22124.

22. Moorthi, P., Premkumar, P., Priyanka, R., Jayachandran, K. S., Anusuyadevi, M. Pathological

changes in hippocampal neuronal circuits underlie age-associated neurodegeneration and

memory loss: Positive clue toward SAD. Neuroscience. 2015 Jun 1;301:90-105.

23. Sadasivam M, Ramatchandirin B, Balakrishnan S, Prahalathan C. TNF-α mediated suppression

of Leydig cell steroidogenesis involves DAX-1. Inflammation Res. 2015;64:549-56.

29

24. Sadasivam M, Ramatchandirin B, Balakrishnan S, Prahalathan C. HDAC7 modulates TNF-α

mediated suppression of Leydig cell steroidogenesis. Mol Cell Biochem. 2015;406:83-90.

25. Inhibition of pathogenic bacterial growth on excision wounds by green synthesized copper oxide

nanoparticles leads to accelerated wound healing activity in Wistar Albino rats. R. Sankar, A.

Baskaran, K.S. Shivashangari, V. Ravikumar, J Mater Sci Mater Med. 26:214, 2015.

26. Chemopreventive potential of fungal taxol against 7, 12-dimethylbenz[a]anthracene induced

mammary gland carcinogenesis in Sprague Dawley rats. Kathamuthu Gokul Raj, Ranganathan

Chidambaram, Krishnamoorthy Varunkumar, Vilwanathan Ravikumar, Mohan Pandi. Eur J

Pharmacol. Nov 15; 767:108-18, 2015.

27. Single and double chain surfactant–cobalt (III) complexes: the impact of hydrophobicity on the

interaction with calf thymus DNA, and their biological activities. Selva kumar Veeralakshmi

selvan Nehru, Gopal Sabapathi, Sankaralingam Arunachalam, Ponnambalam Vennuvanalingam,

Ponnuchamy Kumar, Chidambaram Anusha, Vilwanathan Ravikumar. RSC Adv., 2015, 5,

31746-31758, 2015.

28. Nanostructured delivery growth system for suberoylanilide hydroxamic acid against lung cancer

cells. Sankar R, Karthik S, Subramanian N, Venkateshwaran K, Sonnemann J, Ravikumar V.

Materials Science and Engineering: C. Volume 51, 1 June 2015, Pages 362–368, 2015.

29. Krishnamoorthy Lakshmi Priya and Arockiam Antony Joseph Velanganni (2015). Therapeutic

potential of doxorubicin loaded poly (d, l-lacticco-glycolic acid) against p-

dimethylaminoazobenzene induced liver cancer. Int. J. Phar. and Bio Sci. 6(4):511-

521.(IF:0.36).

30. Selvaraj Rajakumar and Vasanthi Nachiappan (2016) Lipid droplets alleviate cadmium

induced cytotoxicity in Saccharomyces cerevisiae. Received 4th May 2016 , Accepted 3rd

October 2016. DOI: 10.1039/C6TX00187D (Paper) Toxicol. Res., 2017, 6, 30-41.

31. Kannan M, Sivaprakasam C, Prinz WA, Nachiappan V (2016) Endoplasmic reticulum stress

affects the transport of phosphatidylethanolamine from mitochondria to the endoplasmic

reticulum in S.cerevisiae. Biochim Biophys Acta. 2016 Dec;1861(12 Pt A):1959-1967. doi:

10.1016/j.bbalip.2016.09.015.

32. James AW, Gowsalya R, Nachiappan V (2016) Dolichyl pyrophosphate phosphatase-mediated

N-glycosylation defect dysregulates lipid homeostasis in Saccharomyces cerevisiae. Biochim

Biophys Acta.1861(11):1705-1718. doi: 10.1016/j.bbalip.2016.08.004. [Epub ahead of print]

33. Rajakumar S, Bhanupriya N, Ravi C, Nachiappan V (2016) Endoplasmic reticulum stress and

calcium imbalance are involved in cadmium-induced lipid aberrancy in Saccharomyces

cerevisiae. Cell Stress Chaperones.21(5):895-906. doi: 10.1007/s12192-016-0714-4. Epub 2016

Jun 25.

34. Raj A, Nachiappan V (2016) Exposure to benzene metabolites causes oxidative damage in

Saccharomyces cerevisiae. Antonie Van Leeuwenhoek. 109(6):841-54. doi: 10.1007/s10482-

016-0684-7. Epub 2016 Mar 25.

30

35. Rajakumar S, Ravi C, Nachiappan V (2016) Defect of zinc transporter ZRT1 ameliorates

cadmium induced lipid accumulation in Saccharomyces cerevisiae. Metallomics. 8(4):453-60.

doi: 10.1039/c6mt00005c. Epub 2016 Mar 21.

36. Selvaraju K, Gowsalya R, Vijayakumar R, Nachiappan V (2016) MGL2/YMR210w encodes a

monoacylglycerol lipase in Saccharomyces cerevisiae. FEBS Lett. 590(8):1174-86. doi:

10.1002/1873-3468.12136.

37. Sathya, M., Moorthi, P., Premkumar, P., Kandasamy, M., Jayachandran, K. S., Anusuyadevi,

M. Resveratrol intervenes cholesterol and isoprenoids mediated amyloidogenic processing of

AβPP in Familial Alzheimer‟s disease. Journal of Alzheimer's Disease Preprint (2016): 1-22.

38. Karthick, C., Periyasamy, S., Jeyachandran, K. S., Anusuyadevi, M. Intrahippocampal

Administration of Ibotenic Acid Induced Cholinergic Dysfunction via NR2A/NR2B Expression:

Implications of Resveratrol against Alzheimer Disease Pathophysiology. Front Mol Neurosci

2016, 9:28.

39. Ramatchandirin B, Sadasivam M, Kannan A, Prahalathan C. Sirtuin4 regulates

lipopolysaccharide mediated Leydig cell dysfunction J Cell Biochem. 2016;117:904-16.

40. Kalaiarasi, A., Anusha, C., Sankar, R., Rajasekaran, S., John Marshal, J., Muthusamy, K.,

&Ravikumar, V. (2016). Plant isoquinoline alkaloid berberine exhibits chromatin remodeling

by modulation of histone deacetylase to induce growth arrest and apoptosis in the A549 cell line.

Journal of agricultural and food chemistry, 64(50), 9542-9550.

41. Mathuram, T. L., Ravikumar, V., Reece, L. M., Karthik, S., Sasikumar, C. S., & Cherian, K.

M. (2016). Tideglusib induces apoptosis in human neuroblastoma IMR32 cells, provoking sub-

G0/G1 accumulation and ROS generation. Environmental toxicology and pharmacology, 46,

194-205.

42. Ramalingam, V., Varunkumar, K., Ravikumar, V., & Rajaram, R. (2016). Development of

glycolipid biosurfactant for inducing apoptosis in HeLa cells. RSC Advances, 6(68), 64087-

64096.

43. Gunasekaran VP, Nishi K, Ravikumar V and Mathan G. Nuclear shuttling of Y-box binding

protein 1, its clinical relevance to cancer and as a therapeutic target. Bangladesh J Pharmacol,

11: 501-24.

44. Marine steroid derived from Acropora formosa enhances mitochondrial- mediated apoptosis in

non- small cell lung cancer cells. Ramalingam Vaikundamooorthy, Revathidevi Sundramoorthy,

Varunkumar Krishnamoorthy, Ravikumar Vilwanathan, Rajaram Rajendran. Tumor Biol, DOI

10.1007/s13277-016-4947-8, 2016.

45. Renu Sankar, Kanchi Subramanian Shivashangari, Vilwanathan Ravikumar. Integrated poly-

D,L-lactide-co-glycolide/silver nanocomposite: synthesis, characterization and wound healing

potential in Wistar Albino rats. RSC Advances.2016.

46. Sridharan Jeyamohan, Rajesh Kannan Moorthy, Mahesh Kumar Kannan, Antony Joseph

Velanganni Arockiam (2016). Parthenolide induces apoptosis and autophagy through the

31

suppression of PI3K/Akt signaling pathway in cervical cancer. Biotechnol. Lett. 38(8):1251-

1260.

47. Vijayakumar, R., &Nachiappan, V. (2017). Cassia auriculata flower extract attenuates

hyperlipidemia in male Wistar rats by regulating the hepatic cholesterol

metabolism. Biomedicine & Pharmacotherapy, 95, 394-401.

48. Rajendran, V., Krishnegowda, A., &Nachiappan, V. (2017). Antihyperlipidemic activity of

Cassia auriculata flower extract in oleic acid induced hyperlipidemia in Saccharomyces

cerevisiae. Journal of food science and technology, 54(9), 2965-2972.

49. Divya, D., Arul Salomee, K. R., Anusuyadevi, M., Jayachandran, K. S.. "HMGB1: A

Therapeutic Target for Myocardial Infarction." Cardiovasc Ther 7, no. 5 (2017): 555724.

50. Periyasamy, S., Sathya, M., Karthick, C., Kandasamy, M., Shanmugaapriya, S., Tamilselvan, J.,

Jayachandran, K. S., Anusuyadevi, M. Association studies of specific Cholesterol related genes

(APOE, LPL, and CETP) with Lipid profile and memory function: A correlative study among

Rural and Tribal Population of Dharmapuri District, India. J Alzheimers Dis. 2017 (doi:

10.3233/JAD-170272).

51. Velusamy, T., Panneerselvam, S. A., Purushottam, M., Anusuyadevi, M., Pal, P. K., Jain, S.,

Essa, M. M., Guillemin, J. G., Kandasamy, M. Protective effects of antioxidants on neuronal

dysfunction and plasticity in Huntington‟s disease. Oxidative medicine and cellular longevity,

2017.

52. Sankar, R., Rahman, P. K., Varunkumar, K., Anusha, C., Kalaiarasi, A., Shivashangari, K. S.,

&Ravikumar, V. (2017). Facile synthesis of Curcuma longa tuber powder engineered metal nanoparticles for bioimaging applications. Journal of Molecular Structure, 1129, 8-16.

53. Theodore Lemuel Mathuram, Vilwanathan Ravikumar, Lisa M. Reece, Changam Sheela

Sasikumar, Kotturathu Mammen Cherian (2017). Correlative Studies Unravelling the Possible Mechanism of Cell Death in Tideglusib-Treated Human Ovarian Teratocarcinoma-Derived PA-1 Cells. Journal of Environmental Pathology, Toxicology and Oncology, 36(4):321–344.

54. Gnanasekar, Sathishkumar, Jeyaraj Murugaraj, Balakrishnan Dhivyabharathi, Varunkumar

Krishnamoorthy, Pradeep K. Jha, Prabukumar Seetharaman, Ravikumar Vilwanathan, and

Sivaramakrishnan Sivaperumal. (2017) "Antibacterial and cytotoxicity effects of biogenic

palladium nanoparticles synthesized using fruit extract of Couroupita guianensis Aubl." Journal

of Applied Biomedicine, 16(1), 59-65.

55. Anusha, C., Sankar, R., Varunkumar, K., Sivasindhuja, G., &Ravikumar, V. (2017). Fourier

transform-infrared spectroscopy as a diagnostic tool for mosquito coil smoke inhalation toxicity

in Swiss Albino mice. Journal of Molecular Structure, 1149, 128-135.

56. Chidambaram, A., Sekar, A., Kavya, S. H., Chidambaram, R. K., Arunachalam, K.,

Senthilkumar, G. P., &Vilwanathan, R. (2017). Synthesis, characterization, and evaluation of

Cd [L-proline] 2, a novel histone deacetylase inhibitor that induces epigenetic modification of

histone deacetylase isoforms in A549 cells. Investigational new drugs, 35(6), 691-705.

32

57. Thangavel Kavinkumar, Krishnamoorthy Varunkumar, Vilwanathan Ravikumar, Sellaperumal

Manivannan. Anticancer activity of graphene oxide-reduced graphene oxide-silver nanoparticle

composites. Journal of Colloid and Interface Science; 2017, 505, 1125-1133.

58. Ganesan Nithya, Umapathy Devan, Kannan Mahesh Kumar, Arockiam Antony Joseph

Velanganni (2017). A review on the role of Astrocyte Elevated Gene-1 in cancer. Int J Phar Sci

and Res. 8(3): 975-984.

59. Moorthy Rajesh Kannan, Jeyamohan Sridharan, Nagapoosanam Anantha Lakshmi, Arockiam

Antony Joseph Velanganni (2017). Identification and characterization of evolutionary

conserved miRNAs in various types of cancer: in silico and experimental approach. RJLBPCS

3(4): 70-89.

60. Karthick C, Nithiyanandan S, Essa MM, Guillemin GJ, Jayachandran SK, Anusuyadevi M.

Time-dependent effect of oligomeric amyloid-β (1-42)-induced hippocampal neurodegeneration

in rat model of Alzheimer's disease. Neurol Res. 2018 Nov 19:1-12. doi:

10.1080/01616412.2018.1544745.

61. Divya Dasagrandhi, Arul Salomee Kamalabai R, Anusuyadevi Muthuswamy, Angela Marie

Lennox ,Tamilselvan Jayavelu, Vasudharani Devanathan, Jayachandran Kesavan Swaminathan.

Ischemia/reperfusion injury in male guinea pigs: An efficient model to investigate myocardial

damage in cardiovascular complications. Biomedicine & Pharmacotherapy 20, February 2018.

62. Sathya, M., Gobinath, T., Salomy, A., Nisha, M., Kandasamy, M., Essa, M. M., Jayachandran,

K. S., Anusuyadevi, M. Biophysical interaction of resveratrol with sirtuin pathway:

Significance in Alzheimer‟s disease. Frontiers In Bioscience, Landmark, 23, 1380-1390, March

1, 2018.

63. Pattarayan, D., Thimmulappa, R. K., Ravikumar, V., & Rajasekaran, S. (2018). Diagnostic

potential of extracellular microRNA in respiratory diseases. Clinical reviews in allergy &

immunology, 54(3), 480-492.

64. Ramalingam, V., Varunkumar, K., Ravikumar, V., & Rajaram, R. (2018). p53 mediated

transcriptional regulation of long non-coding RNA by 1-hydroxy-1-norresistomycin triggers

intrinsic apoptosis in adenocarcinoma lung cancer. Chemico-biological interactions, 287, 1-12.

65. Ramalingam, V., Varunkumar, K., Ravikumar, V., & Rajaram, R. (2018). Target delivery of

doxorubicin tethered with PVP stabilized gold nanoparticles for effective treatment of lung

cancer. Scientific reports, 8(1), 3815.

66. Vaikundamoorthy, R., Krishnamoorthy, V., Vilwanathan, R., & Rajendran, R. (2018).

Structural characterization and anticancer activity (mcf7 and mda-mb-231) of polysaccharides

fractionated from brown seaweed sargassum wightii. International journal of biological

macromolecules, 111, 1229-1237.

67. Kalaiarasi, A., Sankar, R., Anusha, C., Saravanan, K., Aarthy, K., Karthic, S., &Ravikumar, V.

(2018). Copper oxide nanoparticles induce anticancer activity in A549 lung cancer cells by

inhibition of histone deacetylase. Biotechnology letters, 40(2), 249-256.

33

68. Chidambaram, A., Sundararaju, K., Chidambaram, R. K., Subbiah, R., Jayaraj, J. M.,

Muthusamy, K., &Vilwanathan, R. (2018). Design, synthesis, and characterization of α,

β‐unsaturated carboxylic acid, and its urea based derivatives that explores novel epigenetic

modulators in human non‐small cell lung cancer A549 cell line. Journal of cellular physiology,

233(7), 5293-5309.

69. Nithya Ganesan, Devan Umapathya and Antony Joseph Velanganni Arockiam (2018). LXR-

α/ABCA1 pair enhances and deregulates VEGF modulated by diosgenin in liver cancer cell line

(Huh-7). Int J Pharm Biol Sci., 8 (4): 573-579

70. Nagapoosanam Anantha Lakshmi, Umapathy Devan, Moorthy Rajesh Kannan, Arockiam Antony

Joseph Velanganni. Knockdown of human Telomerase Reverse Transcriptase induces apoptosis via

Bax/Caspase-3 dependent pathway in cervical cancer. Indian J Med Res. (Accepted for publication).

34

COURSE STRUCTURE

M.Sc. BIOCHEMISTRY

SEM Category Code Courses Hrs Crs CIA

Marks

ESE

Marks

TOTAL

Marks

I

Core 1 BC101 Biomolecules 6 6

25 75 100

Core 2 BC102 Enzymes 6 6

25 75 100

Core 3 BC103 Cell and Molecular Biology 6 6

25 75 100

Core 4 BC104 Biochemical Techniques 6 6

25 75 100

Core 5 BC105 Laboratory Courses-I 6 4

40 60 100

Total for Semester-I 30 28

140 360 500

II

Core 6 BC 201 Biochemistry of Signal

Transduction & Regulation

6 6

25 75 100

Core 7 BC 202 Intermediary Metabolism 6 6

25 75 100

Elective BC 203 Elective- I 5 3

25 75 100

Core 8 BC 204 Laboratory Courses –II 6 4

40 60 100

Non major

Elective

BC2ED ED-I 3 2

25 75 100

Total for Semester II 26 21 140 360 500

III

Core 9 BC 301 Immunology 6 6

25 75 100

Core 10 BC 302 Genetic Engineering and

Molecular Techniques

6 6

25 75 100

Elective BC 303 Elective - II 5 3

25 75 100

Core 11 BC 304 Laboratory Courses -III 6 4

40 60 100

Non major

Elective

BC3ED ED-II 3 2

25 75 100

Total for Semester III 26 21

140 360 500

IV

BC 401 Project & Viva Voice 30 20

100

Total for Semester IV 30 20

100

Total hours & credits 112 90 1600

35

ELECTIVE COURSES

BC203 Ecology and Environmental Biology

BC205 Bioinformatics

BC206 Biostatistics

BC207 Chromatin and Epigenetics

BC303 Clinical Biochemistry

BC305 Membrane Biochemistry

BC306 Concept in Neurochemistry

NON MAJOR ELECTIVE COURSES

BC3ED Developmental Biology

BC2ED Genetics

BC3ED-I Computational Biology

M.Phil. BIOCHEMISTRY

Sem no Subject

code

Subject title Hrs./week credits Internal

mark

External

mark

total

I BCMPH01 Research

Methodology

6 4 25 75 100

I BCMPH02 Principles

and

Applications

of Molecular

techniques

6 4 25 75 100

I BCMPH03 Guide paper 6 4 25 75 100

I BCMPH04 Teaching

and

Learning

skills

6 4 25 75 100

II --- Dissertation

and Viva

Voce

6 months 8 50 150 200

Total 24 600