designing a better antimycobacterial
TRANSCRIPT
esignlng a better antim cobacterial
RESEARCH & DEVELOPMENT
French and Gennan re archers ha e foun what th y belie e i the main hydrophilic pathway lhrough the cell wall of Mycobacterium chelonae. repons Science.
They identified a 59 kilodalton cell wall protein that ac a a porin, fonning a water-filled channel for diffu ion of compound in and out of the cell. A better under landing of thi porin y tern rna improve antiba lerial d ign. leading to agent able to overcome the permeability barrier of the mycobacterium cell wall.
ISSN 0156-270319310116-0091$1.0(/> Adl. International Ltd
9
INPHARMA" 16 Jan 1993