development and formative evaluation of the e-health implementation toolkit (e-hit)

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SOFTWARE Open Access Development and formative evaluation of the e-Health Implementation Toolkit (e-HIT) Elizabeth Murray 1* , Carl May 2 , Frances Mair 3 Abstract Background: The use of Information and Communication Technology (ICT) or e-Health is seen as essential for a modern, cost-effective health service. However, there are well documented problems with implementation of e- Health initiatives, despite the existence of a great deal of research into how best to implement e-Health (an example of the gap between research and practice). This paper reports on the development and formative evaluation of an e-Health Implementation Toolkit (e-HIT) which aims to summarise and synthesise new and existing research on implementation of e-Health initiatives, and present it to senior managers in a user-friendly format. Results: The content of the e-HIT was derived by combining data from a systematic review of reviews of barriers and facilitators to implementation of e-Health initiatives with qualitative data derived from interviews of implementers, that is people who had been charged with implementing an e-Health initiative. These data were summarised, synthesised and combined with the constructs from the Normalisation Process Model. The software for the toolkit was developed by a commercial company (RocketScience). Formative evaluation was undertaken by obtaining user feedback. There are three components to the toolkit - a section on background and instructions for use aimed at novice users; the toolkit itself; and the report generated by completing the toolkit. It is available to download from http:// www.ucl.ac.uk/pcph/research/ehealth/documents/e-HIT.xls Conclusions: The e-HIT shows potential as a tool for enhancing future e-Health implementations. Further work is needed to make it fully web-enabled, and to determine its predictive potential for future implementations. Background E-health, or the use of information and communication technology in health care, is seen as essential for a mod- ern, cost-effective health service which is capable of addressing challenges such as improving equity of access and quality of care in a world facing an increasing bur- den of chronic disease [1]. There is an international commitment to e-Health, reflected in very considerable expenditure. The UK government has invested £12.4 bn over 10 years [2] and this is less than the US or many European countries [3]. However, despite the over- whelming political commitment and substantial invest- ment, there has been significant variability in the success of different e-health implementations [4,5]. Many projects have been subject to delay [6], increasing budget overspends, and in some cases, severely negative impacts on the quality and effectiveness of care [7-9]. Although there is a considerable body of research on implementation of e-health [10,11], recent work has cri- ticised both the methodology used in many of the exist- ing reviews of this work, and the narrow focus on organisational issues related to implementation, with lit- tle attention paid to the impact of new technologies on workload, inter-professional relationships, and commu- nication between health professionals and patients [12]. There are many reasons for the difficulties encoun- tered with implementation of e-health. Some of these are likely to parallel those contributing to the gap between research findings and routine clinical care, including a perceived lack of relevance of research to practitioner needs [13]; managers, or other senior staff * Correspondence: [email protected] 1 E-Health Unit, Research Department of Primary Care and Population Health, University College London, Upper Floor 3, Royal Free Hospital, Rowland Hill Street, London NW3 2PF, UK Full list of author information is available at the end of the article Murray et al. BMC Medical Informatics and Decision Making 2010, 10:61 http://www.biomedcentral.com/1472-6947/10/61 © 2010 Murray et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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SOFTWARE Open Access

Development and formative evaluation of thee-Health Implementation Toolkit (e-HIT)Elizabeth Murray1*, Carl May2, Frances Mair3

Abstract

Background: The use of Information and Communication Technology (ICT) or e-Health is seen as essential for amodern, cost-effective health service. However, there are well documented problems with implementation of e-Health initiatives, despite the existence of a great deal of research into how best to implement e-Health (anexample of the gap between research and practice). This paper reports on the development and formativeevaluation of an e-Health Implementation Toolkit (e-HIT) which aims to summarise and synthesise new andexisting research on implementation of e-Health initiatives, and present it to senior managers in a user-friendlyformat.

Results: The content of the e-HIT was derived by combining data from a systematic review of reviews of barriersand facilitators to implementation of e-Health initiatives with qualitative data derived from interviews of“implementers”, that is people who had been charged with implementing an e-Health initiative. These data weresummarised, synthesised and combined with the constructs from the Normalisation Process Model. The softwarefor the toolkit was developed by a commercial company (RocketScience). Formative evaluation was undertaken byobtaining user feedback.There are three components to the toolkit - a section on background and instructions for use aimed at noviceusers; the toolkit itself; and the report generated by completing the toolkit. It is available to download from http://www.ucl.ac.uk/pcph/research/ehealth/documents/e-HIT.xls

Conclusions: The e-HIT shows potential as a tool for enhancing future e-Health implementations. Further work isneeded to make it fully web-enabled, and to determine its predictive potential for future implementations.

BackgroundE-health, or the use of information and communicationtechnology in health care, is seen as essential for a mod-ern, cost-effective health service which is capable ofaddressing challenges such as improving equity of accessand quality of care in a world facing an increasing bur-den of chronic disease [1]. There is an internationalcommitment to e-Health, reflected in very considerableexpenditure. The UK government has invested £12.4 bnover 10 years [2] and this is less than the US or manyEuropean countries [3]. However, despite the over-whelming political commitment and substantial invest-ment, there has been significant variability in the

success of different e-health implementations [4,5].Many projects have been subject to delay [6], increasingbudget overspends, and in some cases, severely negativeimpacts on the quality and effectiveness of care [7-9].Although there is a considerable body of research onimplementation of e-health [10,11], recent work has cri-ticised both the methodology used in many of the exist-ing reviews of this work, and the narrow focus onorganisational issues related to implementation, with lit-tle attention paid to the impact of new technologies onworkload, inter-professional relationships, and commu-nication between health professionals and patients [12].There are many reasons for the difficulties encoun-

tered with implementation of e-health. Some of theseare likely to parallel those contributing to the gapbetween research findings and routine clinical care,including a perceived lack of relevance of research topractitioner needs [13]; managers, or other senior staff

* Correspondence: [email protected] Unit, Research Department of Primary Care and Population Health,University College London, Upper Floor 3, Royal Free Hospital, Rowland HillStreet, London NW3 2PF, UKFull list of author information is available at the end of the article

Murray et al. BMC Medical Informatics and Decision Making 2010, 10:61http://www.biomedcentral.com/1472-6947/10/61

© 2010 Murray et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative CommonsAttribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction inany medium, provided the original work is properly cited.

charged with e-Health implementations not having thetime or inclination to read the large body of literature[14]; inadequacies in the existing research [12]; andthe poor permeability of the managerial: research inter-face[15].In this paper we describe the development and forma-

tive evaluation of an e-Health Implementation Toolkit(e-HIT) (Additional file 1). The e-HIT was developedexplicitly to bridge the managerial:research interface, bymaking the results of a large body of research intoe-Health implementation accessible to senior managersin a simple, user-friendly format. Its development hadbeen explicitly commissioned by the funding body (theNational Institute of Health Research Service Deliveryand Organisation programme) as part of an overall pro-gramme of work examining the barriers and facilitatorsto e-health implementation in the UK National HealthService. The aim of the e-HIT was to summarise andsynthesise research evidence on factors that impede orfacilitate implementation of e-Health initiatives and pre-sent this evidence in a format that could be easilydigested and used by staff considering or planning ane-Health implementation. The aim of this paper is todescribe the process of development and formative eva-luation, and describe the final toolkit, in line with recentcalls for more detailed descriptions of the processes andcontent of complex interventions [16,17].

ImplementationThere were three phases to the development and forma-tive evaluation of the e-HIT (Figure 1):

1. Writing the content;2. Developing the excel spreadsheet;3. Obtaining and incorporating user feedback on thetoolkit.

Writing the contentThe content of the e-HIT was derived by combining atheoretical framework with a literature review and newempirical data.The Normalisation Process ModelThe theoretical framework was the Normalisation Pro-cess Model (NPM) which is a sociological modelexplaining why some new technologies become fullyembedded in routine practice (normalised) and othersdo not. It was initially derived from an extensive seriesof qualitative studies of telemedicine initiatives [18], andsubsequently refined and expanded to apply to theimplementation of all complex interventions in healthcare. The NPM suggests that the degree of “normalisa-tion” of a complex intervention, such as a new e-healthtechnology, depends on the impact of the proposedintervention on four constructs[19]. These constructs

are known as interactional workability, relational inte-gration, skill set workability and contextual integration.Interactional workability (IW) refers to the degree towhich the proposed technology enables (or impedes)interactions between health professionals and patients -e.g. a consultation. Relational integration (RI) refers tothe way in which different professional groups relate toeach other, and how well the proposed technology fits(integrates) with existing relationships, as well as thedegree to which it promotes trust, accountability andresponsibility in inter-group relationships. Skill setworkability (SSW) refers to the degree to which thee-health initiative fits with existing working practices,skill sets, and perceived job role. Contextual integration(CI) refers to the degree to which the proposed e-healthsystem fits (integrates) with the overall goals and struc-ture of the organization (context), as well as the capacityof the organization to undertake the implementation.The more positive the impact of the proposed new tech-nology on these four constructs, the more likely it isthat it will normalise [19].The literature reviewA systematic “review of reviews” was undertaken, withthe aim of summarising the available literature on bar-riers and facilitators to implementation of e-health sys-tems. The methods and findings of this review havebeen described in detail elsewhere [12]. We searchedMEDLINE, EMBASE, CINAHL, PSYCINFO and theCochrane library for reviews of e-Health implementa-tion. Inclusion criteria for this review were that thepaper a) was a review; b) was on e-Health; and c)included information pertinent to implementation. Forthe purposes of this study we defined a review as pro-viding an analytic account of the research literature,and included systematic reviews, narrative reviews andqualitative meta-syntheses. E-health was defined as “theuse of emerging information and communications tech-nology, especially the Internet, to improve or enablehealth and health care”[20], while implementation wasdefined as “all activities that occur between making anadoption commitment and the time that the innovationeither becomes part of the organisational routine, ceasesto be new, or is abandoned” [21]. The search strategycombined the two concepts of e-health and implemen-tation and was limited by publication type to reviews.Titles and abstracts generated by the search strategywere downloaded into an electronic data-base andscreened by two independent reviewers. Papers thatcould not definitely be excluded at this stage wereobtained in full, and read by two independent reviewerswho determined their eligibility against pre-determinedinclusion and exclusion criteria. Data were extracted bytwo independent reviewers and subjected to a thematicanalysis.

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The searches yielded 6,585 citations of which 6,439could be excluded on the basis of the title or abstract.146 full papers were retrieved, of which 19 met the cri-teria for inclusion. The thematic analysis found that the

existing literature focused on the following factors: con-ditions prior to implementation; costs of implementa-tion; importance of evaluation of the new technologyprior to implementation; attitudes of users, particularly

Results from systematic

review

New empirical qualitative data Theory Building

Synthesis and content developmentFirst draft

Web CompanyDesign input

e-HITBeta-version

User group 1First round of formative

feedback

Revised e-HIT

User group 2.Second round of formative

feedback

Finalised e-HIT

Figure 1 Flow chart of e-Hit development.

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health professionals; ease of use of the system; security,confidentiality and standards; education and training;technological issues; communication; and organisationalissues. Conditions prior to the implementation had twocomponents - those within the organisation understudy, and the broader societal context. Examples per-taining to the specific organisation included pre-existingworking relationships, morale, and previous experienceof e-health implementations, while the broader societalcontext could include policy or economic drivers. Costs,including the costs of obtaining the system and thecosts of implementation were seen as important, whilesome authors mentioned the costs of not implementingthe system as also being relevant. Many authors com-mented on the importance of evaluation of systemsprior to their implementation. Professional attitudeswere often perceived as a barrier to implementation,which might or might not be overcome through educa-tion and training. System specific factors included easeof use, and whether concerns about confidentiality,security and standards had been adequately met. Tech-nological issues were important, in terms of fitness forpurpose, as was maintaining good communication bothwithin an organisation and between professionals andpatients [12].Empirical dataThe third source for the content of the e-HIT wasnewly obtained qualitative data, derived from interviewswith a range of “implementers” with responsibility forone or more e-health implementations. The methodsand results of this study have also been described indetail elsewhere [12]. “Implementers” were defined asany person charged with assisting with the implementa-tion of an e-health system. We included chief executivesof trusts, clinical directors, senior managers, ICT staff,and staff working for private companies contracted tosupply, deliver or facilitate specific e-health implementa-tions. We selected three case studies, which betweenthem covered a range of NHS contexts (primary, com-munity and secondary care), types of e-health technol-ogy and relationship with the main sponsor in thisarena, namely Connecting for Health. The selected stu-dies were Choose and Book in one hospital trust and itsmain referring Primary Care Trust in inner London,Picture Archiving and Communication System in a hos-pital trust with several sites in South West England, anda Clinical Nurse Information System in a large urbanhealth board in Scotland. In all cases the implementa-tion had happened between 12 and 36 months earlier.Interviewees were asked for their perceptions of barriersand facilitators to the implementation of the study tech-nology, and the degree to which the technology hadnormalised. Data were coded by two independentresearchers, using the NPM as a coding framework. The

results suggested that the NPM provided a good expla-nation for the variable degrees of normalisation ofthe three study technologies. E-health initiatives thatwere perceived by respondents to have a positive impacton all four constructs were highly likely to normalise.Problems with any one construct should alert policymakers and senior managers to potential difficulties,which need careful consideration and planning. Difficul-ties across all four constructs suggest that the initiativeis relatively unlikely to normalise, and some rethinkmay be needed [12].Combining the data sourcesIn order to create the content of the e-HIT, the mainthemes that arose from the literature review and qualita-tive study were considered in depth, along with the con-structs of the NPM. The themes were synthesised tocreate a database of items which had theoretical andempirical validity. In order to make this collection ofitems accessible and comprehensible, they were groupedinto three main categories: the context; the intervention;and the workforce. These categories emerged from theinterview data from implementers, and were selected asresonating with the approach currently in use by imple-menters. The next task was to reduce the number ofitems in each group to the minimum compatible withadequately addressing all the issues which were judgedimportant on the basis of the three data sources (litera-ture review, qualitative data and theoretical framework).This was done by reviewing all the items, deleting dupli-cates, and clarifying items which were ambiguous. Sub-sequently, each item was operationalised by a statement,which was anchored by extreme negative and extremepositive positions.

Developing the toolkitWe contracted a web design company (RocketScience)who had experience of building toolkits for the publicand private sectors (including the NHS) to provide thesoftware for the toolkit. We undertook an iterative pro-cess of discussion and design which culminated in aprototype toolkit, ready for user testing and feedback.Design issues considered in this phase included thenumber of points on the scale between anchor pointsfor each statement, the number of items on each page,the number of pages, the use of colour, page layout,navigation, and the presentation of results once thetoolkit had been completed. The web design company’sprevious experience was invaluable at this stage.Additional material was written to inform users how

the toolkit had been derived, its aim, how to downloadand complete it, and how to interpret the results. Thesection on interpreting the results emphasised that theseshould be used to alert senior managers to potential pro-blems and encourage constructive, organised thinking

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about the implementation process, not a tickbox or scor-ecard approach which could replace careful thought.Finally, we provided three illustrative case studies for

users to look at, and compare with their own plannedimplementation. These case studies were those used inthe qualitative study described above.

User feedbackA two stage formative evaluation of the e-HIT wasundertaken. For the first stage, the prototype e-HIT wascirculated to a group of e-Health experts. These expertsincluded senior clinicians, managers and academics eachof whom had extensive experience of e-health imple-mentations within the NHS (n = 13). These expertswere asked to complete the e-HIT for an e-Healthinitiative they had personal experience of, and on thebasis of this experience, to comment critically on the e-HIT. Specifically, respondents were asked whether theythought the e-HIT would be useful to senior managersconsidering, planning or undertaking an e-Health imple-mentation, what would make the e-HIT more useful,what were the positive features of the e-HIT, and whatfeatures needed modifying. Respondents were asked tosuggest modifications which would improve the e-HIT,and for other general or specific comments not coveredby the questions listed (Additional File 2).All the experts contacted responded with comments

and discussion. The overall response was overwhel-mingly positive, with comments including “fantastic”and “excellent piece of work”. Specifically, respondentsthought that the non-prescriptive approach and empha-sis on the e-HIT as a sensitizing tool would appeal tosenior managers. Respondents thought that the overalllayout was clear, the language easily comprehensible,and that the main areas of importance were well cov-ered. They liked the sliding scales, space for explanatorytext, and instant feedback. There were also specific sug-gestions for improvement about the navigation, layoutand wording of individual components of the e-HIT,with requests for more information to help with com-pleting some of the questions, and clarification of indivi-dual questions. The experts raised two major concernswhich we were unable to address within the constraintsof the resources available within this research project: a)they judged that the e-HIT would be more useful if itwas fully web-enabled, which would allow multiple usersto compare their results, and hence share experienceeither between different professional groups or acrossmultiple implementation sites; and b) there was a con-cern about how best to disseminate the toolkit.This feedback led to a number of changes, including

redesign of the introductory section, allowing experi-enced users to bypass this, provision of explanatorymouseovers to assist with completion of individual

questions, a more streamlined lay-out and a moredetailed explanation of how to use the report section ofthe toolkit.In the second stage of the formative evaluation, the

revised toolkit was circulated by e-mail to the imple-menters who had been interviewed in the qualitativestudy (n = 23). The e-mail explained that the toolkithad been generated in part from their interview data,and that we were aiming to make the toolkit as helpfulas possible to people like them. Participants were askedto comment on the likely usefulness of the e-HIT, makesuggestions for improvement, and whether it adequatelyreflected their own experience (Additional file 3). Thisround of feedback elicited only minor suggestions from5 respondents, e.g. further clarification of specific items.

ResultsThere are three components to the toolkit - a section onbackground and instructions for use aimed at noviceusers; the toolkit itself; and the report generated bycompleting the toolkit. The background and instructionssection can be bypassed, but for those who wish to useit, it contains advice on how to use the toolkit, includingwhat it is, who should use it, when it should be used,and how it should be used. This section emphasises thatit is a sensitising tool to alert the user to potential pit-falls and allow pre-emptive planning. There is a shortsection on how the toolkit was derived, including linksto further reading for those interested. This introductorysection also contains links to the reports generated bythe illustrative case studies, to give users an idea of whatthe report will look like, and how it compares with theirown experience.The toolkit itself has 6 pages: 3 pages on context, 1 on

the intervention and 2 on workforce issues. Contextincludes organisational factors, national and local poli-cies, and other drivers of the implementation. Interven-tion items address the impact on professional - patientinteractions, inter-professional relationships, and theeffectiveness and cost-effectiveness of the intervention.Workforce items consider the impact of the interventionon workload, workflow, distribution of work betweendifferent user groups, the need for education and train-ing, and the impact on relationships between profes-sional groups. This grouping of items was intendedsolely to help organise and present the items as it wasrecognised that some items could be considered tobelong in two or more categories.Each page contains three items with an extreme nega-

tive and an extreme positive anchoring statement. Theuser is asked to rate their proposed e-health implemen-tation on a scale of 0 - 10 (Figure 2).The final section of the toolkit consists of the report it

generates once the questions have been answered. There

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are four parts to the report: guidance on how to use thereport; graphical displays of the responses for each item;a summary of the comments made by the user; and aproblems and solutions page where the user can notepotential areas of difficulty in the proposed implementa-tion and plans for addressing these. To see one of theillustrative case reports, please see: http://www.ucl.ac.uk/pcph/research/ehealth/documents/case_study-PACS.xls#Scores!A4

DiscussionTo the best of our knowledge, this is the first e-HealthImplementation Toolkit to be developed in this rigor-ous way. The e-HIT has a number of strengths, includ-ing its theoretical underpinning, in line with the call toimprove the design of implementation interventionswith the use of theory [22]. Undertaking a systematicreview of reviews of the field of e-health implementa-tion allowed us to synthesise and summarise a verylarge body of literature in a reasonably efficient man-ner. In addition we obtained new qualitative data, from

a group who have been relatively understudied, namelyimplementers, or people charged with an e-healthimplementation. Including these data helped ensurethat the toolkit incorporated the perceptions of theprofessional group the toolkit is aimed at. The toolkitwas subjected to constructive criticism from a team ofexperts in the field. These strengths in its developmentmay account for the very positive response obtainedduring the formative evaluation. However, there are anumber of weaknesses, and it would be premature toadvise widespread use of the e-HIT until research intoits effectiveness has been undertaken. Weaknessesinclude the relatively small number of people whohave used and commented on the e-HIT, and, as high-lighted during our formative evaluation, it would bemore useful if fully web-enabled. It is also unclear howuseful the e-HIT will be outside the UK NationalHealth Service. The literature review reported experi-ence gained internationally, but the additional qualita-tive data obtained from implementers, and the casestudies are UK-based.

Figure 2 Screen shot of sample page.

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We believe that the e-HIT has the potential to meetan unmet need in the NHS as previous toolkits tend tohave either focused on readiness to implement researchfindings (e.g. those derived from the Promoting Actionon Research Implementation in Health Services (PAR-iHS) framework [23,24])) or on supporting qualityimprovement interventions in health care [25]. Lilleyand Navein developed “The Telemedicine Toolkit” in2000 [26], but this focuses exclusively on telemedicineand is a workbook of 185 pages with exercises. We areseeking further funding to web-enable the toolkit, andsubject it to further critical evaluation, including deter-mining its applicability in an international context.

ConclusionsThe e-HIT is a new tool which has potential for enhan-cing and improving e-Health implementations. Morework is needed to web-enable the toolkit, and to deter-mine its potential predictive power.

Availability and requirementsThe e-HIT is available for downloading from http://www.ucl.ac.uk/pcph/research/ehealth/documents/e-HIT.xls. There are no restrictions on use.

Additional material

Additional file 1: The e-HIT. http://www.ucl.ac.uk/pcph/research/ehealth/documents/e-HIT.xls. Downloadable excel spread sheet of e-HIT.

Additional file 2: feedback questionnaire for Round 1.

Additional file 3: feedback questionnaire for Round 2.

Abbreviationse-HIT: e-Health Implementation Toolkit

AcknowledgementsWe gratefully acknowledge RocketScience for developing the software for thetoolkit, Jo Burns and Trudi James for their assistance with the original project,the advisory group for their thoughtful critique of the e-HIT, and all theinterviewees. This article presents independent research commissioned by theNational Institute for Health Research (NIHR) Service Delivery and Organisation(SDO) Programme. The views expressed in this publication are those of theauthor(s) and not necessarily those of the NHS, the NIHR or the Departmentof Health. The NIHR SDO programme is funded by the Department of Health.

Author details1E-Health Unit, Research Department of Primary Care and Population Health,University College London, Upper Floor 3, Royal Free Hospital, Rowland HillStreet, London NW3 2PF, UK. 2Faculty of Health Sciences, University ofSouthampton, University Road, Southampton, SO17 1BJ, UK. 3Section ofGeneral Practice & Primary Care, Centre for Population and Health Sciences,University of Glasgow, 1 Horselethill Road, Glasgow G12 9LX, UK.

Authors’ contributionsEM led on developing the e-HIT with support from CM and FM. EM wrotethe first and final drafts of the manuscript with input from CM and FM. Allauthors have made substantial contributions to the concept and design ofthe study and to the drafting of the manuscript. All authors have read andagreed the final draft.

Competing interestsThe authors declare that they have no competing interests.

Received: 17 June 2010 Accepted: 18 October 2010Published: 18 October 2010

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BackgroundE-health, or the use of information and communication technology in health care, is seen as essential for a modern, cost-effective health service which is capable of addressing challenges such as improving equity of access and quality of care in a world facing an increasing burden of chronic disease 1. There is an international commitment to e-Health, reflected in very considerable expenditure. The UK government has invested �12.4 bn over 10 years 2 and this is less than the US or many European countries 3. However, despite the overwhelming political commitment and substantial investment, there has been significant variability in the success of different e-health implementations 45. Many projects have been subject to delay 6, increasing budget overspends, and in some cases, severely negative impacts on the quality and effectiveness of care 789. Although there is a considerable body of research on implementation of e-health 1011, recent work has criticised both the methodology used in many of the existing reviews of this work, and the narrow focus on organisational issues related to implementation, with little attention paid to the impact of new technologies on workload, inter-professional relationships, and communication between health professionals and patients 12.There are many reasons for the difficulties encountered with implementation of e-health. Some of these are likely to parallel those contributing to the gap between research findings and routine clinical care, including a perceived lack of relevance of research to practitioner needs 13; managers, or other senior staff charged with e-Health implementations not having the time or inclination to read the large body of literature 14; inadequacies in the existing research 12; and the�poor permeability of the managerial: research interface15.In this paper we describe the development and formative evaluation of an e-Health Implementation Toolkit (e-HIT) (Additional file 1). The e-HIT was developed explicitly to bridge the managerial:research interface, by making the results of a large body of research into e-�Health implementation accessible to senior managers in a simple, user-friendly format. Its development had been explicitly commissioned by the funding body (the National Institute of Health Research Service Delivery and Organisation programme) as part of an overall programme of work examining the barriers and facilitators to e-health implementation in the UK National Health Service. The aim of the e-HIT was to summarise and synthesise research evidence on factors that impede or facilitate implementation of e-Health initiatives and present this evidence in a format that could be easily digested and used by staff considering or planning an e-�Health implementation. The aim of this paper is to describe the process of development and formative evaluation, and describe the final toolkit, in line with recent calls for more detailed descriptions of the processes and content of complex interventions 1617.ImplementationThere were three phases to the development and formative evaluation of the e-HIT (Figure 1):1. Writing the content;2. Developing the excel spreadsheet;3. Obtaining and incorporating user feedback on the toolkit.Writing the contentThe content of the e-HIT was derived by combining a theoretical framework with a literature review and new empirical data.The Normalisation Process ModelThe theoretical framework was the Normalisation Process Model (NPM) which is a sociological model explaining why some new technologies become fully embedded in routine practice (normalised) and others do not. It was initially derived from an extensive series of qualitative studies of telemedicine initiatives 18, and subsequently refined and expanded to apply to the implementation of all complex interventions in health care. The NPM suggests that the degree of �normalisation� of a complex intervention, such as a new e-health technology, depends on the impact of the proposed intervention on four constructs19. These constructs are known as interactional workability, relational integration, skill set workability and contextual integration. Interactional workability (IW) refers to the degree to which the proposed technology enables (or impedes) interactions between health professionals and patients - e.g. a consultation. Relational integration (RI) refers to the way in which different professional groups relate to each other, and how well the proposed technology fits (integrates) with existing relationships, as well as the degree to which it promotes trust, accountability and responsibility in inter-group relationships. Skill set workability (SSW) refers to the degree to which the e-�health initiative fits with existing working practices, skill sets, and perceived job role. Contextual integration (CI) refers to the degree to which the proposed e-health system fits (integrates) with the overall goals and structure of the organization (context), as well as the capacity of the organization to undertake the implementation. The more positive the impact of the proposed new technology on these four constructs, the more likely it is that it will normalise 19.The literature reviewA systematic �review of reviews� was undertaken, with the aim of summarising the available literature on barriers and facilitators to implementation of e-health systems. The methods and findings of this review have been described in detail elsewhere 12. We searched MEDLINE, EMBASE, CINAHL, PSYCINFO and the Cochrane library for reviews of e-Health implementation. Inclusion criteria for this review were that the paper a) was a review; b) was on e-Health; and c) included information pertinent to implementation. For the purposes of this study we defined a review as providing an analytic account of the research literature, and included systematic reviews, narrative reviews and qualitative meta-syntheses. E-health was defined as �the use of emerging information and communications technology, especially the Internet, to improve or enable health and health care�20, while implementation was defined as �all activities that occur between making an adoption commitment and the time that the innovation either becomes part of the organisational routine, ceases to be new, or is abandoned� 21. The search strategy combined the two concepts of e-health and implementation and was limited by publication type to reviews. Titles and abstracts generated by the search strategy were downloaded into an electronic data-base and screened by two independent reviewers. Papers that could not definitely be excluded at this stage were obtained in full, and read by two independent reviewers who determined their eligibility against pre-determined inclusion and exclusion criteria. Data were extracted by two independent reviewers and subjected to a thematic analysis.The searches yielded 6,585 citations of which 6,439 could be excluded on the basis of the title or abstract. 146 full papers were retrieved, of which 19 met the criteria for inclusion. The thematic analysis found that the existing literature focused on the following factors: conditions prior to implementation; costs of implementation; importance of evaluation of the new technology prior to implementation; attitudes of users, particularly health professionals; ease of use of the system; security, confidentiality and standards; education and training; technological issues; communication; and organisational issues. Conditions prior to the implementation had two components - those within the organisation under study, and the broader societal context. Examples pertaining to the specific organisation included pre-existing working relationships, morale, and previous experience of e-health implementations, while the broader societal context could include policy or economic drivers. Costs, including the costs of obtaining the system and the costs of implementation were seen as important, while some authors mentioned the costs of not implementing the system as also being relevant. Many authors commented on the importance of evaluation of systems prior to their implementation. Professional attitudes were often perceived as a barrier to implementation, which might or might not be overcome through education and training. System specific factors included ease of use, and whether concerns about confidentiality, security and standards had been adequately met. Technological issues were important, in terms of fitness for purpose, as was maintaining good communication both within an organisation and between professionals and patients 12.Empirical dataThe third source for the content of the e-HIT was newly obtained qualitative data, derived from interviews with a range of �implementers� with responsibility for one or more e-health implementations. The methods and results of this study have also been described in detail elsewhere 12. �Implementers� were defined as any person charged with assisting with the implementation of an e-health system. We included chief executives of trusts, clinical directors, senior managers, ICT staff, and staff working for private companies contracted to supply, deliver or facilitate specific e-health implementations. We selected three case studies, which between them covered a range of NHS contexts (primary, community and secondary care), types of e-health technology and relationship with the main sponsor in this arena, namely Connecting for Health. The selected studies were Choose and Book in one hospital trust and its main referring Primary Care Trust in inner London, Picture Archiving and Communication System in a hospital trust with several sites in South West England, and a Clinical Nurse Information System in a large urban health board in Scotland. In all cases the implementation had happened between 12 and 36 months earlier. Interviewees were asked for their perceptions of barriers and facilitators to the implementation of the study technology, and the degree to which the technology had normalised. Data were coded by two independent researchers, using the NPM as a coding framework. The results suggested that the NPM provided a good explanation for the variable degrees of normalisation of the�three study technologies. E-health initiatives that were perceived by respondents to have a positive impact on all four constructs were highly likely to normalise. Problems with any one construct should alert policy makers and senior managers to potential difficulties, which need careful consideration and planning. Difficulties across all four constructs suggest that the initiative is relatively unlikely to normalise, and some rethink may be needed 12.Combining the data sourcesIn order to create the content of the e-HIT, the main themes that arose from the literature review and qualitative study were considered in depth, along with the constructs of the NPM. The themes were synthesised to create a database of items which had theoretical and empirical validity. In order to make this collection of items accessible and comprehensible, they were grouped into three main categories: the context; the intervention; and the workforce. These categories emerged from the interview data from implementers, and were selected as resonating with the approach currently in use by implementers. The next task was to reduce the number of items in each group to the minimum compatible with adequately addressing all the issues which were judged important on the basis of the three data sources (literature review, qualitative data and theoretical framework). This was done by reviewing all the items, deleting duplicates, and clarifying items which were ambiguous. Subsequently, each item was operationalised by a statement, which was anchored by extreme negative and extreme positive positions.Developing the toolkitWe contracted a web design company (RocketScience) who had experience of building toolkits for the public and private sectors (including the NHS) to provide the software for the toolkit. We undertook an iterative process of discussion and design which culminated in a prototype toolkit, ready for user testing and feedback. Design issues considered in this phase included the number of points on the scale between anchor points for each statement, the number of items on each page, the number of pages, the use of colour, page layout, navigation, and the presentation of results once the toolkit had been completed. The web design company�s previous experience was invaluable at this stage.Additional material was written to inform users how the toolkit had been derived, its aim, how to download and complete it, and how to interpret the results. The section on interpreting the results emphasised that these should be used to alert senior managers to potential problems and encourage constructive, organised thinking about the implementation process, not a tickbox or scorecard approach which could replace careful thought.Finally, we provided three illustrative case studies for users to look at, and compare with their own planned implementation. These case studies were those used in the qualitative study described above.User feedbackA two stage formative evaluation of the e-HIT was undertaken. For the first stage, the prototype e-HIT was circulated to a group of e-Health experts. These experts included senior clinicians, managers and academics each of whom had extensive experience of e-health implementations within the NHS (n = 13). These experts were asked to complete the e-HIT for an e-Health initiative they had personal experience of, and on the basis of this experience, to comment critically on the e-HIT. Specifically, respondents were asked whether they thought the e-HIT would be useful to senior managers considering, planning or undertaking an e-Health implementation, what would make the e-HIT more useful, what were the positive features of the e-HIT, and what features needed modifying. Respondents were asked to suggest modifications which would improve the e-HIT, and for other general or specific comments not covered by the questions listed (Additional File 2).All the experts contacted responded with comments and discussion. The overall response was overwhelmingly positive, with comments including �fantastic� and �excellent piece of work�. Specifically, respondents thought that the non-prescriptive approach and emphasis on the e-HIT as a sensitizing tool would appeal to senior managers. Respondents thought that the overall layout was clear, the language easily comprehensible, and that the main areas of importance were well covered. They liked the sliding scales, space for explanatory text, and instant feedback. There were also specific suggestions for improvement about the navigation, layout and wording of individual components of the e-HIT, with requests for more information to help with completing some of the questions, and clarification of individual questions. The experts raised two major concerns which we were unable to address within the constraints of the resources available within this research project: a) they judged that the e-HIT would be more useful if it was fully web-enabled, which would allow multiple users to compare their results, and hence share experience either between different professional groups or across multiple implementation sites; and b) there was a concern about how best to disseminate the toolkit.This feedback led to a number of changes, including redesign of the introductory section, allowing experienced users to bypass this, provision of explanatory mouseovers to assist with completion of individual questions, a more streamlined lay-out and a more detailed explanation of how to use the report section of the toolkit.In the second stage of the formative evaluation, the revised toolkit was circulated by e-mail to the implementers who had been interviewed in the qualitative study (n = 23). The e-mail explained that the toolkit had been generated in part from their interview data, and that we were aiming to make the toolkit as helpful as possible to people like them. Participants were asked to comment on the likely usefulness of the e-HIT, make suggestions for improvement, and whether it adequately reflected their own experience (Additional file 3). This round of feedback elicited only minor suggestions from 5 respondents, e.g. further clarification of specific items.ResultsThere are three components to the toolkit - a section on background and instructions for use aimed at novice users; the toolkit itself; and the report generated by completing the toolkit. The background and instructions section can be bypassed, but for those who wish to use it, it contains advice on how to use the toolkit, including what it is, who should use it, when it should be used, and how it should be used. This section emphasises that it is a sensitising tool to alert the user to potential pitfalls and allow pre-emptive planning. There is a short section on how the toolkit was derived, including links to further reading for those interested. This introductory section also contains links to the reports generated by the illustrative case studies, to give users an idea of what the report will look like, and how it compares with their own experience.The toolkit itself has 6 pages: 3 pages on context, 1 on the intervention and 2 on workforce issues. Context includes organisational factors, national and local policies, and other drivers of the implementation. Intervention items address the impact on professional - patient interactions, inter-professional relationships, and the effectiveness and cost-effectiveness of the intervention. Workforce items consider the impact of the intervention on workload, workflow, distribution of work between different user groups, the need for education and training, and the impact on relationships between professional groups. This grouping of items was intended solely to help organise and present the items as it was recognised that some items could be considered to belong in two or more categories.Each page contains three items with an extreme negative and an extreme positive anchoring statement. The user is asked to rate their proposed e-health implementation on a scale of 0 - 10 (Figure 2).The final section of the toolkit consists of the report it generates once the questions have been answered. There are four parts to the report: guidance on how to use the report; graphical displays of the responses for each item; a summary of the comments made by the user; and a problems and solutions page where the user can note potential areas of difficulty in the proposed implementation and plans for addressing these. To see one of the illustrative case reports, please see: http://www.ucl.ac.uk/pcph/research/ehealth/documents/case_study-PACS.xls#Scores!A4DiscussionTo the best of our knowledge, this is the first e-Health Implementation Toolkit to be developed in this rigorous way. The e-HIT has a number of strengths, including its theoretical underpinning, in line with the call to improve the design of implementation interventions with the use of theory 22. Undertaking a systematic review of reviews of the field of e-health implementation allowed us to synthesise and summarise a very large body of literature in a reasonably efficient manner. In addition we obtained new qualitative data, from a group who have been relatively understudied, namely implementers, or people charged with an e-health implementation. Including these data helped ensure that the toolkit incorporated the perceptions of the professional group the toolkit is aimed at. The toolkit was subjected to constructive criticism from a team of experts in the field. These strengths in its development may account for the very positive response obtained during the formative evaluation. However, there are a number of weaknesses, and it would be premature to advise widespread use of the e-HIT until research into its effectiveness has been undertaken. Weaknesses include the relatively small number of people who have used and commented on the e-HIT, and, as highlighted during our formative evaluation, it would be more useful if fully web-enabled. It is also unclear how useful the e-HIT will be outside the UK National Health Service. The literature review reported experience gained internationally, but the additional qualitative data obtained from implementers, and the case studies are UK-based.We believe that the e-HIT has the potential to meet an unmet need in the NHS as previous toolkits tend to have either focused on readiness to implement research findings (e.g. those derived from the Promoting Action on Research Implementation in Health Services (PARiHS) framework 2324)) or on supporting quality improvement interventions in health care 25. Lilley and Navein developed �The Telemedicine Toolkit� in 2000 26, but this focuses exclusively on telemedicine and is a workbook of 185 pages with exercises. We are seeking further funding to web-enable the toolkit, and subject it to further critical evaluation, including determining its applicability in an international context.ConclusionsThe e-HIT is a new tool which has potential for enhancing and improving e-Health implementations. More work is needed to web-enable the toolkit, and to determine its potential predictive power.Availability and requirementsThe e-HIT is available for downloading from http://www.ucl.ac.uk/pcph/research/ehealth/documents/e-HIT.xls. There are no restrictions on use.Abbreviationse-HIT: e-Health Implementation ToolkitCompeting interestsThe authors declare that they have no competing interests.Authors� contributionsEM led on developing the e-HIT with support from CM and FM. EM wrote the first and final drafts of the manuscript with input from CM and FM. All authors have made substantial contributions to the concept and design of the study and to the drafting of the manuscript. All authors have read and agreed the final draft.
BackgroundE-health, or the use of information and communication technology in health care, is seen as essential for a modern, cost-effective health service which is capable of addressing challenges such as improving equity of access and quality of care in a world facing an increasing burden of chronic disease 1. There is an international commitment to e-Health, reflected in very considerable expenditure. The UK government has invested �12.4 bn over 10 years 2 and this is less than the US or many European countries 3. However, despite the overwhelming political commitment and substantial investment, there has been significant variability in the success of different e-health implementations 45. Many projects have been subject to delay 6, increasing budget overspends, and in some cases, severely negative impacts on the quality and effectiveness of care 789. Although there is a considerable body of research on implementation of e-health 1011, recent work has criticised both the methodology used in many of the existing reviews of this work, and the narrow focus on organisational issues related to implementation, with little attention paid to the impact of new technologies on workload, inter-professional relationships, and communication between health professionals and patients 12.There are many reasons for the difficulties encountered with implementation of e-health. Some of these are likely to parallel those contributing to the gap between research findings and routine clinical care, including a perceived lack of relevance of research to practitioner needs 13; managers, or other senior staff charged with e-Health implementations not having the time or inclination to read the large body of literature 14; inadequacies in the existing research 12; and the�poor permeability of the managerial: research interface15.In this paper we describe the development and formative evaluation of an e-Health Implementation Toolkit (e-HIT) (Additional file 1). The e-HIT was developed explicitly to bridge the managerial:research interface, by making the results of a large body of research into e-�Health implementation accessible to senior managers in a simple, user-friendly format. Its development had been explicitly commissioned by the funding body (the National Institute of Health Research Service Delivery and Organisation programme) as part of an overall programme of work examining the barriers and facilitators to e-health implementation in the UK National Health Service. The aim of the e-HIT was to summarise and synthesise research evidence on factors that impede or facilitate implementation of e-Health initiatives and present this evidence in a format that could be easily digested and used by staff considering or planning an e-�Health implementation. The aim of this paper is to describe the process of development and formative evaluation, and describe the final toolkit, in line with recent calls for more detailed descriptions of the processes and content of complex interventions 1617.ImplementationThere were three phases to the development and formative evaluation of the e-HIT (Figure 1):1. Writing the content;2. Developing the excel spreadsheet;3. Obtaining and incorporating user feedback on the toolkit.Writing the contentThe content of the e-HIT was derived by combining a theoretical framework with a literature review and new empirical data.The Normalisation Process ModelThe theoretical framework was the Normalisation Process Model (NPM) which is a sociological model explaining why some new technologies become fully embedded in routine practice (normalised) and others do not. It was initially derived from an extensive series of qualitative studies of telemedicine initiatives 18, and subsequently refined and expanded to apply to the implementation of all complex interventions in health care. The NPM suggests that the degree of �normalisation� of a complex intervention, such as a new e-health technology, depends on the impact of the proposed intervention on four constructs19. These constructs are known as interactional workability, relational integration, skill set workability and contextual integration. Interactional workability (IW) refers to the degree to which the proposed technology enables (or impedes) interactions between health professionals and patients - e.g. a consultation. Relational integration (RI) refers to the way in which different professional groups relate to each other, and how well the proposed technology fits (integrates) with existing relationships, as well as the degree to which it promotes trust, accountability and responsibility in inter-group relationships. Skill set workability (SSW) refers to the degree to which the e-�health initiative fits with existing working practices, skill sets, and perceived job role. Contextual integration (CI) refers to the degree to which the proposed e-health system fits (integrates) with the overall goals and structure of the organization (context), as well as the capacity of the organization to undertake the implementation. The more positive the impact of the proposed new technology on these four constructs, the more likely it is that it will normalise 19.The literature reviewA systematic �review of reviews� was undertaken, with the aim of summarising the available literature on barriers and facilitators to implementation of e-health systems. The methods and findings of this review have been described in detail elsewhere 12. We searched MEDLINE, EMBASE, CINAHL, PSYCINFO and the Cochrane library for reviews of e-Health implementation. Inclusion criteria for this review were that the paper a) was a review; b) was on e-Health; and c) included information pertinent to implementation. For the purposes of this study we defined a review as providing an analytic account of the research literature, and included systematic reviews, narrative reviews and qualitative meta-syntheses. E-health was defined as �the use of emerging information and communications technology, especially the Internet, to improve or enable health and health care�20, while implementation was defined as �all activities that occur between making an adoption commitment and the time that the innovation either becomes part of the organisational routine, ceases to be new, or is abandoned� 21. The search strategy combined the two concepts of e-health and implementation and was limited by publication type to reviews. Titles and abstracts generated by the search strategy were downloaded into an electronic data-base and screened by two independent reviewers. Papers that could not definitely be excluded at this stage were obtained in full, and read by two independent reviewers who determined their eligibility against pre-determined inclusion and exclusion criteria. Data were extracted by two independent reviewers and subjected to a thematic analysis.The searches yielded 6,585 citations of which 6,439 could be excluded on the basis of the title or abstract. 146 full papers were retrieved, of which 19 met the criteria for inclusion. The thematic analysis found that the existing literature focused on the following factors: conditions prior to implementation; costs of implementation; importance of evaluation of the new technology prior to implementation; attitudes of users, particularly health professionals; ease of use of the system; security, confidentiality and standards; education and training; technological issues; communication; and organisational issues. Conditions prior to the implementation had two components - those within the organisation under study, and the broader societal context. Examples pertaining to the specific organisation included pre-existing working relationships, morale, and previous experience of e-health implementations, while the broader societal context could include policy or economic drivers. Costs, including the costs of obtaining the system and the costs of implementation were seen as important, while some authors mentioned the costs of not implementing the system as also being relevant. Many authors commented on the importance of evaluation of systems prior to their implementation. Professional attitudes were often perceived as a barrier to implementation, which might or might not be overcome through education and training. System specific factors included ease of use, and whether concerns about confidentiality, security and standards had been adequately met. Technological issues were important, in terms of fitness for purpose, as was maintaining good communication both within an organisation and between professionals and patients 12.Empirical dataThe third source for the content of the e-HIT was newly obtained qualitative data, derived from interviews with a range of �implementers� with responsibility for one or more e-health implementations. The methods and results of this study have also been described in detail elsewhere 12. �Implementers� were defined as any person charged with assisting with the implementation of an e-health system. We included chief executives of trusts, clinical directors, senior managers, ICT staff, and staff working for private companies contracted to supply, deliver or facilitate specific e-health implementations. We selected three case studies, which between them covered a range of NHS contexts (primary, community and secondary care), types of e-health technology and relationship with the main sponsor in this arena, namely Connecting for Health. The selected studies were Choose and Book in one hospital trust and its main referring Primary Care Trust in inner London, Picture Archiving and Communication System in a hospital trust with several sites in South West England, and a Clinical Nurse Information System in a large urban health board in Scotland. In all cases the implementation had happened between 12 and 36 months earlier. Interviewees were asked for their perceptions of barriers and facilitators to the implementation of the study technology, and the degree to which the technology had normalised. Data were coded by two independent researchers, using the NPM as a coding framework. The results suggested that the NPM provided a good explanation for the variable degrees of normalisation of the�three study technologies. E-health initiatives that were perceived by respondents to have a positive impact on all four constructs were highly likely to normalise. Problems with any one construct should alert policy makers and senior managers to potential difficulties, which need careful consideration and planning. Difficulties across all four constructs suggest that the initiative is relatively unlikely to normalise, and some rethink may be needed 12.Combining the data sourcesIn order to create the content of the e-HIT, the main themes that arose from the literature review and qualitative study were considered in depth, along with the constructs of the NPM. The themes were synthesised to create a database of items which had theoretical and empirical validity. In order to make this collection of items accessible and comprehensible, they were grouped into three main categories: the context; the intervention; and the workforce. These categories emerged from the interview data from implementers, and were selected as resonating with the approach currently in use by implementers. The next task was to reduce the number of items in each group to the minimum compatible with adequately addressing all the issues which were judged important on the basis of the three data sources (literature review, qualitative data and theoretical framework). This was done by reviewing all the items, deleting duplicates, and clarifying items which were ambiguous. Subsequently, each item was operationalised by a statement, which was anchored by extreme negative and extreme positive positions.Developing the toolkitWe contracted a web design company (RocketScience) who had experience of building toolkits for the public and private sectors (including the NHS) to provide the software for the toolkit. We undertook an iterative process of discussion and design which culminated in a prototype toolkit, ready for user testing and feedback. Design issues considered in this phase included the number of points on the scale between anchor points for each statement, the number of items on each page, the number of pages, the use of colour, page layout, navigation, and the presentation of results once the toolkit had been completed. The web design company�s previous experience was invaluable at this stage.Additional material was written to inform users how the toolkit had been derived, its aim, how to download and complete it, and how to interpret the results. The section on interpreting the results emphasised that these should be used to alert senior managers to potential problems and encourage constructive, organised thinking about the implementation process, not a tickbox or scorecard approach which could replace careful thought.Finally, we provided three illustrative case studies for users to look at, and compare with their own planned implementation. These case studies were those used in the qualitative study described above.User feedbackA two stage formative evaluation of the e-HIT was undertaken. For the first stage, the prototype e-HIT was circulated to a group of e-Health experts. These experts included senior clinicians, managers and academics each of whom had extensive experience of e-health implementations within the NHS (n = 13). These experts were asked to complete the e-HIT for an e-Health initiative they had personal experience of, and on the basis of this experience, to comment critically on the e-HIT. Specifically, respondents were asked whether they thought the e-HIT would be useful to senior managers considering, planning or undertaking an e-Health implementation, what would make the e-HIT more useful, what were the positive features of the e-HIT, and what features needed modifying. Respondents were asked to suggest modifications which would improve the e-HIT, and for other general or specific comments not covered by the questions listed (Additional File 2).All the experts contacted responded with comments and discussion. The overall response was overwhelmingly positive, with comments including �fantastic� and �excellent piece of work�. Specifically, respondents thought that the non-prescriptive approach and emphasis on the e-HIT as a sensitizing tool would appeal to senior managers. Respondents thought that the overall layout was clear, the language easily comprehensible, and that the main areas of importance were well covered. They liked the sliding scales, space for explanatory text, and instant feedback. There were also specific suggestions for improvement about the navigation, layout and wording of individual components of the e-HIT, with requests for more information to help with completing some of the questions, and clarification of individual questions. The experts raised two major concerns which we were unable to address within the constraints of the resources available within this research project: a) they judged that the e-HIT would be more useful if it was fully web-enabled, which would allow multiple users to compare their results, and hence share experience either between different professional groups or across multiple implementation sites; and b) there was a concern about how best to disseminate the toolkit.This feedback led to a number of changes, including redesign of the introductory section, allowing experienced users to bypass this, provision of explanatory mouseovers to assist with completion of individual questions, a more streamlined lay-out and a more detailed explanation of how to use the report section of the toolkit.In the second stage of the formative evaluation, the revised toolkit was circulated by e-mail to the implementers who had been interviewed in the qualitative study (n = 23). The e-mail explained that the toolkit had been generated in part from their interview data, and that we were aiming to make the toolkit as helpful as possible to people like them. Participants were asked to comment on the likely usefulness of the e-HIT, make suggestions for improvement, and whether it adequately reflected their own experience (Additional file 3). This round of feedback elicited only minor suggestions from 5 respondents, e.g. further clarification of specific items.ResultsThere are three components to the toolkit - a section on background and instructions for use aimed at novice users; the toolkit itself; and the report generated by completing the toolkit. The background and instructions section can be bypassed, but for those who wish to use it, it contains advice on how to use the toolkit, including what it is, who should use it, when it should be used, and how it should be used. This section emphasises that it is a sensitising tool to alert the user to potential pitfalls and allow pre-emptive planning. There is a short section on how the toolkit was derived, including links to further reading for those interested. This introductory section also contains links to the reports generated by the illustrative case studies, to give users an idea of what the report will look like, and how it compares with their own experience.The toolkit itself has 6 pages: 3 pages on context, 1 on the intervention and 2 on workforce issues. Context includes organisational factors, national and local policies, and other drivers of the implementation. Intervention items address the impact on professional - patient interactions, inter-professional relationships, and the effectiveness and cost-effectiveness of the intervention. Workforce items consider the impact of the intervention on workload, workflow, distribution of work between different user groups, the need for education and training, and the impact on relationships between professional groups. This grouping of items was intended solely to help organise and present the items as it was recognised that some items could be considered to belong in two or more categories.Each page contains three items with an extreme negative and an extreme positive anchoring statement. The user is asked to rate their proposed e-health implementation on a scale of 0 - 10 (Figure 2).The final section of the toolkit consists of the report it generates once the questions have been answered. There are four parts to the report: guidance on how to use the report; graphical displays of the responses for each item; a summary of the comments made by the user; and a problems and solutions page where the user can note potential areas of difficulty in the proposed implementation and plans for addressing these. To see one of the illustrative case reports, please see: http://www.ucl.ac.uk/pcph/research/ehealth/documents/case_study-PACS.xls#Scores!A4DiscussionTo the best of our knowledge, this is the first e-Health Implementation Toolkit to be developed in this rigorous way. The e-HIT has a number of strengths, including its theoretical underpinning, in line with the call to improve the design of implementation interventions with the use of theory 22. Undertaking a systematic review of reviews of the field of e-health implementation allowed us to synthesise and summarise a very large body of literature in a reasonably efficient manner. In addition we obtained new qualitative data, from a group who have been relatively understudied, namely implementers, or people charged with an e-health implementation. Including these data helped ensure that the toolkit incorporated the perceptions of the professional group the toolkit is aimed at. The toolkit was subjected to constructive criticism from a team of experts in the field. These strengths in its development may account for the very positive response obtained during the formative evaluation. However, there are a number of weaknesses, and it would be premature to advise widespread use of the e-HIT until research into its effectiveness has been undertaken. Weaknesses include the relatively small number of people who have used and commented on the e-HIT, and, as highlighted during our formative evaluation, it would be more useful if fully web-enabled. It is also unclear how useful the e-HIT will be outside the UK National Health Service. The literature review reported experience gained internationally, but the additional qualitative data obtained from implementers, and the case studies are UK-based.We believe that the e-HIT has the potential to meet an unmet need in the NHS as previous toolkits tend to have either focused on readiness to implement research findings (e.g. those derived from the Promoting Action on Research Implementation in Health Services (PARiHS) framework 2324)) or on supporting quality improvement interventions in health care 25. Lilley and Navein developed �The Telemedicine Toolkit� in 2000 26, but this focuses exclusively on telemedicine and is a workbook of 185 pages with exercises. We are seeking further funding to web-enable the toolkit, and subject it to further critical evaluation, including determining its applicability in an international context.ConclusionsThe e-HIT is a new tool which has potential for enhancing and improving e-Health implementations. More work is needed to web-enable the toolkit, and to determine its potential predictive power.Availability and requirementsThe e-HIT is available for downloading from http://www.ucl.ac.uk/pcph/research/ehealth/documents/e-HIT.xls. There are no restrictions on use.Abbreviationse-HIT: e-Health Implementation ToolkitCompeting interestsThe authors declare that they have no competing interests.Authors� contributionsEM led on developing the e-HIT with support from CM and FM. EM wrote the first and final drafts of the manuscript with input from CM and FM. All authors have made substantial contributions to the concept and design of the study and to the drafting of the manuscript. All authors have read and agreed the final draft.

24. Kitson AL, Rycroft-Malone J, Harvey G, McCormack B, Seers K, Titchen A:Evaluating the successful implementation of evidence into practiceusing the PARiHS framework: theoretical and practical challenges.Implement Sci 2008, 3(1):1.

25. Akl EA, Treweek S, Foy R, Francis J, Oxman AD: NorthStar, a support toolfor the design and evaluation of quality improvement interventions inhealthcare. Implement Sci 2007, 2(19):19.

26. Lilley R, Navein J: The Telemedicine Tool Kit. A Workbook for NHSDoctors, Nurses and Managers. Oxford: Radcliffe Medical Press 2000.

Pre-publication historyThe pre-publication history for this paper can be accessed here:http://www.biomedcentral.com/1472-6947/10/61/prepub

doi:10.1186/1472-6947-10-61Cite this article as: Murray et al.: Development and formative evaluationof the e-Health Implementation Toolkit (e-HIT). BMC Medical Informaticsand Decision Making 2010 10:61.

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Murray et al. BMC Medical Informatics and Decision Making 2010, 10:61http://www.biomedcentral.com/1472-6947/10/61

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