diclofenac research
DESCRIPTION
Diclofenac compound Research contains : 1- Introduction about The Pharmacological Class. 2- Name of the drug (IUPAC, generic and trade names). 3- Structure of the drug (drawn by Chemsketch program). 4- Synthesis of the drug (drawn by Chemsketch program). 5- Spectral data of the drug (UV, IR, NMR and Mass). 6- Uses, Side effects and Contraindications.TRANSCRIPT
Research OnNon Steroidal Anti-Inflammatory Drugs
(NSAIDs)
Content :
1- Introduction about The Pharmacological Class.
2- Name of the drug (IUPAC, generic and trade names).
3- Structure of the drug (drawn by Chemsketch program).
4- Synthesis of the drug (drawn by Chemsketch program).
5- Spectral data of the drug (UV, IR, NMR and Mass).
6- Uses, Side effects and Contraindications.
7- A table describing the role of each student in the group in fulfilling the project.
Diclofenac Research
The Pharmacological Class
• Diclofenac belongs to the class of acetic acid derivatives and related substances of non-steroidal anti-inflammatory and antirheumatic products.
• This medicine works by reducing substances in the body that cause pain and inflammation.
• Diclofenac is used to treat pain or inflammation caused by arthritis or ankylosing spondylitis.
Diclofenac Research
IUPAC, Generic & Trade Names
• IUPAC Name: 2-(2,6-dichloranilino) phenylacetic acid.
• Generic Name: Diclofenac Sodium, Diclofenac Potassium &
Diclofenac epolamine.
• Trade Name: Voltaren, Cataflam, Flector & Anuva
Diclofenac Research
Diclofenac Research
Diclofenac Sodium
Diclofenac Potassium
Diclofenac epolamineDiclofenac (as free acid)
Structure of Drug
Diclofenac Research
Diclofenac_3D
Synthesis of the drug
Diclofenac Research
Spectral Data of the Drug
Diclofenac Research
IR
Diclofenac Sodium
Diclofenac Research
Spectral Data of the Drug
UVSpectrum of Diclofenac in NaOH
Diclofenac Research
Spectral Data of the Drug
NMR
Diclofenac Research
Spectral Data of the Drug
Mass
Diclofenac Research
• Diclofenac is used to treat pain, inflammatory disorders, and dysmenorrhea.
• Diclofenac is used commonly to treat mild to moderate postoperative or post-traumatic pain, in particular when inflammation is also present, and is effective against menstrual pain and endometriosis.
Uses
Side Effects
• This medicine may cause life-threatening heart or circulation problems such as heart attack or stroke, especially if you use it long term.
• This medicine may also cause serious effects on the stomach or intestines, including bleeding or perforation (forming of a hole).
Diclofenac Research
Contraindication
• Do not use diclofenac just before or after heart bypass surgery (coronary artery bypass graft, or CABG).
• Diclofenac is contraindicated in hypersensitivity, active peptic ulcer, moderate to severe hepatic disease and in pregnancy.
• Those with Alcohol abuse, Colitis, Crohn's disease, diverticulitis, gastric ulcer, Diabetes mellitus, Hemorrhoids, Hepatitis, renal disease, Rectal irritation.
Diclofenac Research