Differential Diagnosis of Leprosy

Hypopigmented patch on buttock

Hypopigmented patch

Pityriasis versicolar

A hypo pigmented patch in an 8 year old child

Patch/Macular hypopigmented type of skin lesion

• Nevus Anemicus

• Pityriasis Alba

• Early Vitligo

• Pityriasia versicolar

• Post inflammatory hypo-pigmentation

• Differential diagnosis for

Erythematous plaque lesion with well defined annular border .

– Skin lesions are few.

– One erythematous large plaque is usually present, with well-

defined annular borders that are elevated and that slope down

into an atrophic center.

– central healing.

– Lesions can be dry and scaly, hypohidrotic, and hairless.

– Another presentation involves a large, asymmetric

hypopigmented macule.

DDX of well defined annular peripheraly raised lesions

• Tinea corporis

• Cutaneous lesihmaniasis

• Cutaneous tuberclosis

• Psoriasis

• Pityriasis Rosea – Herald patch

• Granuloma annulare

DDx of multiple nodules on the skin

Lepromatous leprosy father and child

Lepromatous leprosy

Secondary Syphilis

DCL

DDx of multiple nodules on skin

• Lepromatous leprosy

• Diffuse Cutaneous Leishmaniasis

• kaposi Sarcoma

• Nodulocystic acne

• Deep fungal infection

• PKDL

• Secondary Syphilis

• Neuro fibromatosis

DDX of Type I Reversal Reaction

• Erysipela

• Cellulitis

• abscess

Leprosy reaction lesions

DDx of Nerve Enlargement

• Neuro fibromatosis

• Primary Amyloidosis

Nerve enlargement