differential pulse polarographic determination of ...differential pulse polarographic determination...
TRANSCRIPT
-
Differential pulse polarographic Determination
of Submicrogram Quantities of Carmustin and Related Compounds
in Biological Samples
Bartosek I., Daniel S., Sykora S.
J.Pharmac.Sci. 67, 1160-1163 (1978)
This copy, scanned from an Author’s reprint, is intended for personal perusal only.
Other uses require permission of the American Pharmaceutical Association.
Other works by Stan Sykora can be found at www.ebyte.it
Abstract:
A polarographic method was developed to determine the antineoplastic agent carmustin and other nitrosoureas,
such as N-methyl-N-nitrosourea and N-cyclohexyl-N-nitrosourea, in biological liquids at levels well below
1µg/ml or g. The stability of carmustin in different media was investigated to prevent losses during
administration or essay. Examples of nitrosourea determination in biological samples are given.
Keywords: Polarography, Carmustin, Nitrosourea, Biological samples, Antineoplastics