For better dentistry

DISCOVERANEWAPPROACHTOCOMFORT

Clinicallyprovenimmediateandlastingsensitivityreliefwithjustoneapplication!

PLUSthestainremovalstrengthyoutrust!

PERFORMANCE meets PROTECTION

POWERED BY NOVAMIN®

PLUS the stain removal strength you trust!

Immediate Sensitivity Relief, Stain Removal and Polishing

“I have now used NUPRO® Sensodyne® prophy paste for over a year and I am very satisfied with the effectiveness of cleaning my patients‘ teeth. Additionally, I clearly see that my patients who suffer from dentin hypersensitivities experience an immediate relief. Therefore, I started to use the prophy paste on those patients before the scaling procedure. This positive effect automatically links to my professional ability to reduce their pain sensation and therefore they are more likely to come back for preventive recall sessions. Returning patients confirmed that this effect even lasted for a couple of weeks.“

Dott. Antonella Abbinante

The prophy paste that cleans and polishes teeth and provides immediate and long lasting sensitivity relief at the same time.

UseNUPROSensodyneprophypaste:

•CleaningandPolishingPRIORtoandAFTERscaling

•CleaningandPolishingPRIORtoandAFTERrootplanning

•Desensitizingwithimmediatereliefofsensitivityafterjustoneapplication1,2

•Desensitizingwithlastingsensitivityreliefafterjustoneapplication1,2

Stain Removal DesensitizingPolishing

NUPRO® Sensodyne®

DesensitizingPastes

ProphylaxisPastes

1 DENTSPLYdataonfile.2 Millemanetal.NUPROSensodyneprophylaxispastewithNovaMinforthetreatmentofdentinhypersensitivity:A4-weekclinicalstudy.AmJoD,Vol.25,No.52012;262-268

The Problem of Dentin-Hypersensitivity

NUPRO®Sensodyne®,prophypastewithNovaMin®,apatentedcalciumphosphatetechnology.NovaMin®releasescalciumandphosphatetothetoothsurfaceandtherebyclosesopendentintubulesandprovidesimmediateandlastingsensitivityrelief1,2.

1 DENTSPLYDataonfile.2 Millemanetal.NUPROSensodyneprophylaxispastewithNovaMinforthetreatmentofdentinhypersensitivity:A4-weekclinicalstudy.AmJoD,Vol.25,No.52012;262-2683 AddyM.Dentinehypersensitivity:definition,prevalence,distributionandaetiology.InToothWearandSensitivity.AddyM,EmberyG,EdgarWM,OrchardsonR,eds.MartinDunitz,London.pp239-248,2000.4 Ref.JournalofBiomedical&PharmaceuticalEngineeringI:I(2007)34-39

How NovaMin® works1

* Protective layer that is naturally built by saliva, structurally and chemically similar to natural tooth mineral4

Calcium-phosphate crystallizes to build a new hydroxyapatite-like layer* over exposed dentin and within the dentin tubules

CalciumSodiumPhosphosilicate

1. pH elevation: Reacts with saliva: Na ions released; pH level elevated to range essential for HA formation.

2. Mineral releaseBioavailable Ca2+ and P5+ ions released, increasing their concentration in salvia.

3. Crystal Building Ca2+ and P5+ ions interact with demineralized dentin to build new HA like crystals and occlude dentin tubules.

Open dentin tubules.

ph:8.0-8.5

Si

Si

Si

Na

Na

Na

P

PP

PP

Ca

Ca

NovaMin® releases the natural building blocks of teeth to help build an enamel-like mineral layer

•30%ofadultpatientssufferfromDentin-Hypersensitivity3

•Dentin-Hypersensitivityisasharptransientpainduetoopentubulesonexposeddentin•Dentin-HypersensitivityoftenoccursafterProfessionalToothCleaning

Solution: The NovaMin®-Effect

•Immediatesensitivityreliefafteronlyoneapplication•Lastingsensitivityreliefafteronlyoneapplication

2 double blind clinical studies with a total of 288 patients with hypersensitivity

In vitro studies, NovaMin® in NUPRO® Sensodyne® Prophylaxis Paste showed:

•Near-completetubuleocclusionafter1minuteinteethtreatedwithNUPRO®Sensodyne®ProphylaxisPaste3

Two Clinical Studies confirm1,2

Before After

2000x magnification

NUPRO® Sensodyne® Prophylaxis Paste with NovaMin®

Prophylaxis paste with ACP

2000x magnification

Before After

Prophylaxis paste with Pro-Argin™

2000x magnification

Before After

Prophylaxis paste with Recaldent™

2000x magnification

Before After

Comparison

1 DENTSPLYdataonfile.2 Millemanetal.NUPROSensodyneprophylaxispastewithNovaMinforthetreatmentofdentinhypersensitivity:A4-weekclinicalstudy.AmJoD,Vol.25,No.52012;262-2683 DENTSPLYdataonfile.

Clinical Study CTP-0011, Air-Blast Method Clinical Study CTP-0022, Air-Blast Method

3

2

1

0

GroupANUPROSensodyne

prophypastewithfluoride

GroupBNUPROClassic

prophypastew/ofluoride(control)

GroupCNUPROSensodyne

prophypastew/ofluoride

Pre-TreatmentPost-ProphyDay28

Sens

itivi

tys

cale

*

*Howsensitiveareyourteeth?

0=Tooth/Subjectdoesnotrespondtoairstimulus. 1=Tooth/Subjectrespondstoairstimulusbutdoesnotrequest discontinuationofstimulus.

3

2

1

0

GroupANUPROSensodyne

prophypastew/ofluoride

GroupBNUPROSensodyne

prophypastewithfluoride

GroupCNUPROClassic

prophypastew/ofluoride(control)

Pre-TreatmentPost-ProphyDay28

Sens

itivi

tys

cale

*

2=Tooth/Subjectrespondstoairstimulusandrequests discontinuationormovesfromstimulus. 3=Tooth/Subjectrespondstoaitstimulus,considersstimulus tobepainful,andrequestsdiscontinuationofstimulus.

•NUPRO®Sensodyne®prophypasteshowednosignificantchangeinnumberoftubulioccludedafteracidtrials3

With a portfolio of products designed for continuous care

PERFORMANCE meets PROTECTION

First line treatment Second line treatment

11

2

3

2

Desensitizing Toothpaste

1st choice for everyday management (treatment and prevention) of dentin hypersensitivity

Daily dental care at home

Prophylaxis and Desensitizing Paste

For patients with dentin hypersensitivity who require a prophylaxis treatment

• ImmediateReliefofSensitivity1,2

• LastingSensitivityRelease1,2

• ProphyPasteprovidingStainRemoval,PolishingandDesensitizinginoneproduct

Chairside treatment All cases

Dentin Sealant

Additional protection for patients with intractable /severe dentin hypersensitivity

• Additionalprotectionfromabrasionandaciderosion

• Alleviationfromcervicalhypersensitivity

• Cervicalabrasionispreventedforatleast3months

Additional treatment Severe cases

1 DENTSPLYdataonfile.2 Millemanetal.NUPROSensodyneprophylaxispastewithNovaMinforthetreatmentofdentinhypersensitivity:A4-weekclinicalstudy.AmJoD,Vol.25,No.52012;262-268

Packaging Information

Stain removal, Polishing and Desensitizing all in One

K792

0008

9-02

©D

ENTS

PLY

DeT

rey

27.0

2.20

13

DENTSPLY DeTrey GmbHDe-Trey-Str.178467KonstanzGERMANYwww.dentsply.euPhone+49(0)7531583-0

DENTSPLY LtdBuilding1AviatorPark,StationRoadADDLESTONE,KT152PGUNITEDKINGDOMPhone+44(0)1932853422

1 DENTSPLYdataonfile.2 Millemanetal.NUPROSensodyneprophylaxispastewithNovaMinforthetreatmentofdentinhypersensitivity:A4-weekclinicalstudy.AmJoD,Vol.25,No.52012;262-2683 Dataonfile.InvitrotestingcomparingprophypastecontainingACP,CCP-ACP,Pro-ArginandNovaMin4 JCDvol.xx1;3;2010NUPRO®isaregisteredtrademarkofDENTSPLYInternationaland/oritssubsidiaries.Sensodyne®,NovaMin®andtheringsdeviceareregisteredtrademarksoftheGlaxoSmithKlinegroupofcompanies.

Clinically proven immediate sensitivity relief1,2

Lasting sensitivity relief1,2

Unique NovaMin® Technology

Stain removal & polishing formulas

Polish Polish

with Fluoride

ORANGE SPEARMINT

NUPRO® Sensodyne®

prophy paste StainRemoval StainRemoval

without Fluoride

ORANGE SPEARMINT

801534S1801530S1

801535S1801531S1

801522S1801510S1

801523S1801511S1

801540S1801536S1

801541S1801537S1

801528S1801524S1

801529S1801525S1

Jar (340 g) Cups (Box of 175 Patient Dose Cups)

Excellentfluoriderelease3

Enhancedcalciumrelease3

Pleasantflavorchoices

Additional benefits Fastactivation&releaseofcalciumandphosphate4Moistureactivatedratherthandependentonacidormechanicalagitation

PeppermintOilfree

Dye&Glutenfree

SLSfree(SodiumLaurylSulfate)