disorder relate of stress

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    Disorder relate of

    StressChanxin Liu

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    Stressor

    Hypothalamus

    SympatheticNervousSystem

    AdrenalMedulla AdrenalCortex PituitaryGland

    Neural impulses

    activate various glandsand smooth muscles

    Stress hormones carried

    via blood stream torelevant organs and muscles

    Fight-or-flight

    response

    (1)

    (3)

    (2)

    (5)

    (4) (7)

    (6)

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    Fight-or-flight Response

    A stressful situation activates the

    hypothalamus, which, in turn, controls two

    neuroendocrine systems: The sympathetic system The adrenal-cortical system

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    Fight-or-flight Response

    The sympathetic nervous system (SNS),

    responding to neural impulses from the

    hypothalamus (1),

    activates various organs and smoothmuscles under its control (2).

    SNS also signals the adrenal medulla (3) to

    release epinephrines and norepinephrine intothe bloodstream (4)

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    Fight-or-flight Response

    ACTH also signals the other endocrine

    glands to release some 30 hormones.

    The combined effect of the various stress

    hormones carried via the bloodstream plusthe neural activity of the sympathetic division

    of the autonomic nervous system constitute

    the fight-or-flight response

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    Stress and Disease

    Direct effects of stress on health Chronic overarousal (e.g. Coronary heart disease)

    The immune system

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    Diathesis-stress Paradigm

    Diathesis refers most precisely to aconstitutional predisposition toward illness

    But the term may be extended to any

    characteristic or set of characteristics of aperson that increases his or her chance ofdeveloping a disorder.

    Possessing the diathesis for a disorder

    increases a persons risk of developing it butdoes not by any means guarantee that adisorder will develop

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    Diathesis-stress Paradigm

    Both diathesis and stress are necessary in

    the development of disorders

    The psychopathology is unlikely to result

    from the impact of any single factor, e.g.childhood experiences, coping strategies,

    culture influences, etc

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    Low High

    Level of stress

    High

    Low

    Psyc

    hopathology

    High diathesis

    (individual X)

    Low diathesis

    (individual Y)

    (a) An individual with a large dose of the diathesis requires only a moderate amount

    of stress to develop psychopathology, whereas an individual with a small dose of thediathesis requires a large amount of stress to precipitate a breakdown

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    Low High

    Level of stress

    High

    Low

    Psyc

    hopathology

    Diathesis

    Absent

    Diathesis

    present

    (b) The diathesis is dichotomous; stress level has no effect on those without the

    diathesis

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    Low High

    Level of stress

    High

    Low

    Psyc

    hopathology

    Diathesis

    Absent

    High loading

    (c) The diathesis is continuous; increasing stress increases psychopathology for all

    people with at least a minimal amount of the diathesis

    Minimal loading

    Diathesis

    present

    (low to

    high

    loading)

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    Somatic-weakness theory

    Genetic factors, prior illnesses, diet, and the

    like may disrupt a particular organ system,

    which may then become weak and vulnerable

    to stress E.g. a congenitally weak respiratory system

    might predispose the individual to asthma

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    Specific-reaction theory

    Each person has his own patterns ofautomatic response to stress

    The bodily system that is the most

    responsive becomes a likely candidate forthe locus of a locus of a subsequent psycho-physiological disorder

    E.g. someone reacting to stress with elevated

    blood pressure may be more susceptible toessential hypertension