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openbiolabs.org Charlottesville Open Bio Labs Culturing Creativity

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openbiolabs.org

Charlottesville Open Bio LabsCulturing Creativity

openbiolabs.org

Synthetic BiologyAugust 18th, 2015

openbiolabs.org

What we’re gonna talk about...● What is Synthetic Biology?● Brief History● Disruptive Trends● The Shifting Mindset● The Landscape Today● What’s Coming Next● How You Can Participate

openbiolabs.org

What is Synthetic Biology?

openbiolabs.org

Sythetic BiologyA new interdisciplinary field combining engineering principles with biology to (re-)design and fabricate biological components and systems that do not already exist in the natural world.

openbiolabs.org

Biotechs are hot!

openbiolabs.org

Brief History

openbiolabs.org

1953 - DNA Structure discovered by Watson & Crick1978 - Insulin made from bacteria (instead of pigs)1983 - Genetically-modified Tobacco (from breeding)2003 - Human Genome Project Completed

openbiolabs.org

Disruptive Trends

openbiolabs.org

Plummeting Costs

openbiolabs.org

Democratization of KnowledgeOpen platforms to disseminate dataCommunity of online learnersSynthetic Biology is the new programming

openbiolabs.org

The Shifting Mindset

openbiolabs.org

Traditional Genetic Engineering

First: Remove a particular gene...

Then: ...see what happens.

openbiolabs.org

New Way of Thinking:Assuming :

DNA is interchangeableEach gene performs a function

What could be BUILT by putting genes together?

openbiolabs.org

Program Bacteria Like A Machine

openbiolabs.org

Cloning ClassWednesday, August 26th6:30pm1216 Harris St.

Insert DNA into bacteria in a real lab!

Sign up at openbiolabs.org

openbiolabs.org

The Landscape Today

openbiolabs.org

Synthetic Biology community

Engaging students and the public in the development of the new field of synthetic biology. International

Genetically Engineered Machine

openbiolabs.org

Biobricks are modular genetic components with which you can create complex circuits.

Every year, iGEM teams must submit new and fully characterized biobricks to the catalog.

Huge open-access repository of Biobricks.

Biobrick foundation

openbiolabs.org

Emergence of DIY Biology2009: Genspace was founded.Today: Over 60 DIY labs globally.

Hardware- OpenTrons

Software- ApE

Bioware- Real Vegan Cheese

openbiolabs.org

What’s Coming Next?

openbiolabs.org

Evident with the internet and MOOCS

Evident with the maker movement

Interdisciplinary cooperation

New way of learning

openbiolabs.org

New way of conducting scienceUnprecedented global collaboration

Crowd-sourced experiments, solutions and datasets

Citizen scientists make an impact

openbiolabs.org

We have an intellectual density unheard of anywhere else.

The only thing missing is biology and science.

Why C-ville is ripe to lead!

openbiolabs.org

Open Bio Labs fills the science shaped hole in your heart.

openbiolabs.org

We are a non-profit organizationWe’re passionateWe see potentialWe know you feel the same

DIY Community!

openbiolabs.org

Cloning ClassWednesday, August 26th6:30pm1216 Harris St.

Insert DNA into bacteria in a real lab!

Sign up at openbiolabs.org

openbiolabs.org

Open Bio Labs is for the person:who is worried about their family health and wants to conduct a genetic analysis.

who is intellectually curious and wants to explore how biology intersects with their current discipline.

who has a million dollar idea but no where to pursue it.

who wants to be engaged in a scientific community.

openbiolabs.org

How you can help.Businesses:

Sponsor Open Bio Labs

Individuals: Donate, apply for membership, sign up for a class, and volunteer!

Everyone: Like us on Facebook, Follow us on Twitter, and provide feedback to [email protected]

openbiolabs.org

Charlottesville Open Bio LabsCulturing Creativity

[email protected]