Age Quotient

How to Get Better with Age

Al Sears MD

Paradigm ShiftParadigm Shift•The old model of anti-aging medicine

could only slow the decline of aging. In other words, “delay the inevitable.”

•While useful, this outdated approach fails to empower the individual...

• ...or demonstrate how you can personally evolve to grow stronger and smarter with age.

Body Intelligence:Body Intelligence:How Young is Your How Young is Your

Body?Body?

• We are now able to look at the total measure of your body’s ability and directly improve it... making your body act younger than your physical age.

• What makes this all possible is a brand new way of looking at your body and how young it is.

• The starting point is the biomarker.

What is a What is a Biomarker?Biomarker?

•A biomarker tells us how “old” a particular function of your body is... regardless of chronological age.

•Lung capacity and bone density are good examples of biomarkers.

Biomarkers Biomarkers Change with AgeChange with Age•Biomarkers predictably change.

•The changes can be measured, tracked and monitored over time.

•Biomarkers can also be acted upon to alter their change.

Biomarkers Biomarkers Reveal Your Reveal Your

““Biological AgBiological Agee ””

•Biomarkers can be used to calculate true “age” of a function

•For example, a 60-year old man with above average lung power would have “younger” lungs than his peers.

Biomarkers Deteriorate Biomarkers Deteriorate at a at a

Predictable RatePredictable Rate•By analyzing data from the population

at large, we can systematically determine how biomarkers change over time.

•Using our example of a 60-year old man, we can compare the individual to the known average lung capacity of someone that age.

•Have a look at this graph...

Loss of Lung Loss of Lung Power Power

How Old are Your How Old are Your Lungs? Lungs?

Using pulmonary function tests, we determine the overall output and performance of your lungs.

Then we chart your capacity and compare it with the general population.

This gives us a true measure of the “biological age” of your lungs.

Your lungs may test “older” or “younger” than your chronological age.

Why Measure Your Why Measure Your Lungs? Lungs?

The Framingham Heart Study discovered your lungs are the number one predictor of death.

The smaller your lungs, the greater your chance of dying... of ALL causes.

Your lung power can be increased and expanded through intervention.

Your lungs are but one of over a dozen biomarkers that determine your true biological age.

Miller, J. A. “Making Old Age Measure Up,” Aging. Vol. 2, Art. 12. Boca Raton, FL.: Social Issues Resource Series, Inc., 1981.

14 Biomarkers of 14 Biomarkers of Aging Aging

Cardiac AgePulmonary AgeVascular AgeNeurologic AgeMuscular AgeAdipose AgeBone AgeRenal AgeHepatic AgeVision AgeSkin AgeImmunological AgeHormonal AgeTelomere Age

Taken Together Biomarkers Taken Together Biomarkers

Determine Your Overall Determine Your Overall Biological Age Biological Age

•The combined average determines your overall “biological age.”

•This quantifies your health more reliably than chronological age.

•Through intervention, your biological age can drop over time... allowing you to grow younger as you age.

Aging Biomarkers Can Be Aging Biomarkers Can Be Reversed Through Reversed Through

InterventionIntervention

• Lung power is expandable by challenging your maximal capacity.

• This is the opposite of what fitness “gurus” tell you to do through conventional aerobic training.

• Each of the 13 biomarkers has a set protocol of interventions designed to improve function and capacity.

• The overall effect is to make your body act younger than your physical age.

Your Biological Age Can Be Your Biological Age Can Be Converted to Your Converted to Your ““Age Age

QuotientQuotient””

• The AQ is much simpler than other age measurements that use medical acronyms and strange numbers.

• Currently, test results come back with numbers and ranges that mean little to the patient.

• If I told you your FVC (a measure of lung power) was 4.2 liters... is that good or bad?

• These results are not helpful or useful to the person trying to understand how well they’re doing or where they need to improve.

Age Quotient is a Simple Age Quotient is a Simple CalculationCalculation

With AQ, we take your chronological age, divide by your biological age, and then multiply by 100.

• So if you’re 50-years old, and your biological age is 54, then your AQ is 93. (The average being 100.)

• Or if you’re 60-years old, and your biological age is 47, your AQ is 128.

With AQ You Can Get BETTER With AQ You Can Get BETTER As You Get OlderAs You Get Older

Conventional anti-aging medicine attempts to slow your inevitable decline... with no thought of getting BETTER over time.

• AQ is open ended with no upper limit.

• AQ provides a means to improve yourself as you age by elevating specific functions and performance levels of youth.

Your AQ Has Limitless Your AQ Has Limitless PotentialPotential

• 220 minus Chronological Age = Maximum Achieved Heart Rate

• 220 minus x = 220; x = 0

• 220 divided by 0 = INFINITY

• When your biological age for maximum heart rate is zero, your AQ hits INFINITY.

Patient M.F.Patient M.F.Age 58 to 61Age 58 to 61

Baseline 6M 12M 18M 24M 30M

Biological Marker Age 56 52 52 43 51 44

Patient M.F.Patient M.F.Age 58 to 61Age 58 to 61

Baseline 6M 12M 18M 24M 30M

Age Quotient 103 111 113 137 117 138

Patient L.S.Patient L.S.Age 68 to 69Age 68 to 69

Baseline 12M

Biological Marker Age 77 54

Patient L.S.Patient L.S.Age 68 to 69Age 68 to 69

Baseline 12M

Age Quotient 88 127

PACE Group Average % Body Fat

Baseline 1 2 3 4 5 633% 32% 30% 28% 25% 25% 24%

PACE Group Adipose Bio-Age

Baseline 1 2 3 4 5 663 58.5 52.5 48.5 37.5 35 31

PACE Group Adipose A/Q

Baseline 1 2 3 4 5 673 78 87 95 122 131 148

PACE Group: RF

PACE Group: Terri

PACE Group: Dijon

New Anti-Aging Reports• Biomarkers– Cardiac Age– Pulmonary Age– Neurologic Age– Renal Age– Musculoskeletal Age– Bone Mineral Density Age– Hepatic Age– Ophthalmologic Age – Skin Age– Vascular Age– Immunologic Age– Hormonal Age– Telomere Age• Mean Telomere Length• Number of Critically Short Telomeres

Age Quotient

Al Sears MD

Wellness Research Foundation 11903 Southern Blvd., Ste. 208

Royal Palm Beach, FL 33411 866-792-1035

www.alsearsmd.com