dose levels
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Expectedhealtheffectsforanadultassumingthecumulativetotalradiationexposurewasallreceivedwithinawee stime.Forchildren,theeffectscanbeexpectedathalfthesedoselevels.
TOTALEXPOSURE ONSET&DURATIONOFINITIALSYMPTOMS&DISPOSITION
30to70R From6-12hours:nonetoslightincidenceoftransientheadacheandnausea;
vomitinginupto5percentofpersonnelinupperpartofdoserange.Mild
lymphocytedepressionwithin24hours.Fullrecoveryexpected.(Fetusdamage
possiblefrom50Randabove.)
70to150R From2-20hours:transientmildnauseaandvomitingin5to30percentof
personnel.Potentialfordelayedtraumaticandsurgicalwoundhealing,
minimalclinicaleffect.Moderatedropinlymphocycte,platelet,and
granulocytecounts.Increasedsusceptibilitytoopportunisticpathogens.
Fullrecoveryexpected.
150to300R From2hourstothreedays:transienttomoderatenauseaandvomitingin
20to70percent;mildtomoderatefatigabilityandwea nessin25to60
percentofpersonnel.At3to5wee s:medicalcarerequiredfor10to50%.
Athighendofrange,deathmayoccurtomaximum10%.Anticipatedmedical
problemsincludeinfection,bleeding,andfever.Woundingorburnswill
geometricallyincreasemorbidityandmortality.
300to530R From2hourstothreedays:transienttomoderatenauseaandvomitingin50
to90percent;mildtomoderatefatigabilityin50to90percentofpersonnel.
At2to5wee s:medicalcarerequiredfor10to80%.Atlowendofrange,
lessthan10%deaths;athighend,deathmayoccurformorethan50%.
Anticipatedmedicalproblemsincludefrequentdiarrhealstools,anorexia,
increasedfluidloss,ulceration.Increasedinfectionsusceptibilityduring
immunocompromisedtime-frame.Moderatetoseverelossoflymphocytes.
Hairlossafter14days.
530to830R From2hourstotwodays:moderatetoseverenauseaandvomitingin80to
100percentofpersonnel;From2hourstosixwee s:moderatetosevere
fatigabilityandwea nessin90to100percentofpersonnel.At10daysto
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7/31/2019 Dose Levels
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5wee s:medicalcarerequiredfor50to100%.Atlowendofrange,death
mayoccurformorethan50%atsixwee s.Athighend,deathmayoccur
for99%ofpersonnel.Anticipatedmedicalproblemsincludedeveloping
pathogenicandopportunisticinfections,bleeding,fever,lossofappetite,
GIulcerations,bloodydiarrhea,severefluidandelectrolyteshifts,capillary
lea ,hypotension.Combinedwithanysignificantphysicaltrauma,survival
rateswillapproachzero.
830RPlus From30minutesto2days:severenausea,vomiting,fatigability,wea ness,
dizziness,anddisorientation;moderatetoseverefluidimbalanceandheadache.
Bonemarrowtotaldepletionwithindays.CNSsymptomsarepredominantat
higherradiationlevels.Few,ifany,survivorsevenwithaggressiveand
immediatemedicalattention.