RAI Congress Center, Amsterdam, The Netherlands

30 June - 4 July 2018

20th Congress of the International Society for Human and Animal Mycology (ISHAM)

www.isham2018.org

Program

www.isham2018.org

Regional scientific committeeAndreas GrollBart-Jan KullbergBas ZwaanEd KuijperFrank van de VeerdonkHan WöstenJohan MaertensJohan Mouton

Katrien LagrouMichael NeteaOliver CornelyPedro CrousPeter-Michael RathPieter Jan HaasTeun BoekhoutWendy van de Sande

Download the official ISHAM2018 APP

Do not forget to use #ISHAM2018 when posting photos and comments of the event on your social networks.

International scientific committeeAhmed Fahal Alexandro BonifazAna Alastruey-IzquierdoAndreas Groll, MunsterAndrew Ullman, WurzburgAnuradha ChowdharyArnaldo ColomboArturo CasadevallArunaloke Chakrabarti Ashraf IbrahimAxel BrakhageBernhard HubeBill SteinbachBirgit WillingerChristophe d’EnfertCornelia Lass-FloerlCornelius ClancyDarius Armstrong JonesDavid AndesDavid Denning David PerlinDimitrios KontoyiannisDonald SheppardDonna MacCallumElizabeth JohnsonEmanuel Roilides Eric DannaouiFlavio Queiros TellesGordon Brown

Hamid BadaliHan LiHideoki OgawaJean-Pierre Gangneux Jesus GuineaJoe HeitmanJoerg SteinmannJohan MaertensJosef Guarro, Josef MeletiadisKatrien LagrouLewis White, Livio PaganoLuis Ostrosky-Zeichner Mahmoud Ghannoum Maiken Arendrup Malcolm RichardsonManuel Cuenca, Marcus TeixeraMartin HoeniglMartin SchallerMatteo BasettiMatthew FisherMaurizio SanguinettiMichaela LacknerNathan Wiederhold Neil GowNelish GovenderNicolai Klimko

Nina Gunde-Cimerman Oliver CornelyOliver Kurzai Olivier LortholaryPatrice le PapePeter PappasPeter-Michael RathRetno WahyuningsihRoxana VitaleRuo-yu Li, Beijing, China Russel Edward Ruth AshbeeRyoji TsuboiSean Zhang,Sevtap Arikan Sharon Chen Shawn LockhartStephane BretagneStephane Ranque Thomas WalshTom Chiller, Tom PattersonTom RogersWanqing LiaoWei-da LiuWieland MeyerYee-Chun Chen

INTR

OD

UCT

ION INTRODUCTION

Dear Colleagues and Friends,

It is our great pleasure to extend a warm welcome to all of you to the Netherlands and to the 20th Congress of the International Society for Human and Animal Mycology (ISHAM).

ISHAM 2018 aims to provide clinicians, scientists and students an exciting opportunity to meet at an international forum dedicated solely to the study of medical mycology. Many colleagues from all over the world will be joining us including many young scientists and students. We are proud to host such an important meeting in our country. The Netherlands has a strong track record in mycology with leading scientists at the Center of Expertise in Mycology RadboudUMC/CWZ in Nijmegen, the Westerdijk Fungal Biodiversity Institute (former CBS) in Utrecht, and many others.

Together with the scientific committee, we have done our best to put together a strong and attractive scientific program spanning all hot topics in basic, translational and clinical mycology. We hope that you will find the meeting rewarding and that you will enjoy your stay in our capital city, Amsterdam, which is a place of many inspiring and surprising faces. No other city mixes cosmopolitan style and relaxed atmosphere quite like Amsterdam where our hospitable nature attracts an excitingly diverse population.

We wish you an enriching congress and an excellent stay in Amsterdam.

The organizing committee Paul E. Verweij, Congress President Ferry Hagen, TreasurerJacques F. Meis, Vice-president Sybren de Hoog, Chair Scientific Committee

Dear Delegates,

The ISHAM Congress fulfils our mission of education and sharing the latest research and discussion across a wide spectrum of topics in medical mycology. This Congress will be no exception. I welcome all of you and hope that this Congress will serve as a catalyst for strengthening international collaboration. On behalf of the ISHAM council I would like to thank everyone who has been involved in organising this event, and our industrial partners.

Best wishes, Malcolm RichardsonISHAM President

Saturday 30 June 201808:30 - 15:30 Young ISHAM symposium12:30 Registration Open16:00 - 17:30 Opening ceremony17:30 - 19:00 Welcome reception

Sunday 1 July 2018 Fundamental Clinical Translational Special Interest Working Groups

08:00 - 09:00 Forum General Assembly ISHAM09:00 - 10:00 Forum Plenary session I10:00 - 10:30 Break10:30 - 12:00

Parallel session I

E103 S1.1 Basic mechanisms of antifungal immunity

Forum S1.2 Mycotic keratitis

E102 S1.3 The Mycobiome in Health and Disease

E104 S1.4 Chromoblastomycosis: the role of immunity

E107 S1.5 EFISG/ECMM Aspergillus guidelines

E108 S1.6 ISHAM Working Group: Genotyping of Cryptococcus

12:00 - 13:30 Lunch break 12:15 - 13:15 Ruby lounge Poster Pitch session I12:30 - 13:30 Forum Sponsored symposium13:30 - 14:30 Forum Plenary session II14:30 - 15:00 Break15:00 - 16:30 Parallel session II E103

S2.1 Nutrition and stress

Forum S2.2 Candida auris

E102 S2.3 Antifungal stewardship

E104 S2.4 Global epidemiology & One Health of Aspergillus fumigatus

E107 S2.5 CLSI & EUCAST

E108 S2.6 ISHAM Working Group: Medical Phycology

16:30 - 18:00 Parallel session III E103 S3.1 Evolutionary strategies of fungal pathogens

Forum S3.2 AIDS-related mycoses

E102 S3.3 Indoor fungi and sick buildings

E104 S3.4 ISHAM Working Group: Veterinary Mycology

E107 S3.5 Pneumocystis

E108 S3.6 Late breakers

E105 S3.7 Behind the scene of scientific publising

18:00 - 19:00 Ruby Lounge Poster Pitch session II

Monday 2 July 2018 09:00 - 10:00 Forum Plenary session III10:00 - 10:30 Break10:30 - 12:00 Parallel sessions IV E103

S4.1 Molecular and cell biology of fungal pathogens

Forum S4.2 Cryptococcal meningitis clinical trials

E102 S4.3 Antifungals Pipeline session

E104 S4.4 Invasive infections in Asia

E107 S4.5 New insights in the management of invasive fungal disease in haematology

E108 S4.6 MMCR case report session

12:00 - 13:30 Lunch Break 12:15 - 13:15 Ruby Lounge Poster Pitch session III13:30 - 14:30 Forum Plenary session IV14:30 - 15:00 Break15:00 - 16:30 Parallel session V E103

S5.1 Hot topics in Taxonomy – Can we define fungal species borders?

Forum S5.2 Superficial dermatophytes

E102 S5.3 Beyond antifungal / host directed therapy

E104 S5.4 Mucoralean infections

E107 S5.5 From Basic Science to Patient Care

E108 S5.6 ISHAM Working Group: Fusarium

16:30 - 18:00 Parallel session VI E103 S6.1 Functional genomics and systems biology

Forum S6.2 ABPA

E102 S6.3 Tropical implantation diseases

E104 S6.4 Aspergillus terreus frontline

E107 S6.5 Malassezia in humans and animals

E108 S6.6 Surveillance azole resistance

18:00 - 20:00 Ruby Lounge Poster Pitch session IV19:00 Young ISHAM Beachparty

Tuesday 3 July 2018 09:00 - 10:00 Forum Plenary session V10:00 - 10:30 Break10:30 - 12:00 Parallel session VII E103

S7.1 Fungal biofilms Forum S7.3 The Real Pathogens: Ajellomycetaceae

E102 S7.4 Why do patients get aspergillosis?

E104 S7.5 Scedosporium

E107 S7.6 ISHAM Working Group: Sporothrix

E108 S7.7 Pediatrics

E106 S7.2 Fungal Interactions with Epithelium Trigger Innate Immune Activation

12.00 - 13.30 Lunch break12:15 - 13:00 Ruby Lounge Poster Pitch session V13:30 - 14:30 Forum Plenary session VI14:30 - 15:00 Break15:00 - 16:30 Parallel session VIII E103

S8.1 Host-pathogen interactions - the pathogen perspective

Forum S8.3 Management of fungal resistance

E102 S8.4 DNA Barcoding

E104 S8.5 Challenges in mucosal and invasive candidiasis

E107 S8.6 ECMM Educational Symposium

E108 S8.7 New developments in dermatomycosis

E106 S8.2 Milestones in medical mycology: history in modern light

16:30 - 18.00 Parallel sessions IX E103 S9.1 Genotyping in the NGS era

Forum S9.3 Dosing antifungal from the XXS to XXXL

E102 S9.4 MALDI-TOF in filamentous fungi

E104 S9.5 Recent advances in diagnosing aspergillosis

E108 S9.7 Cryptococcus-host interactions

E106 S9.2 Developments in Chinese medical mycology

18:00 Congress Dinner

Wednesday 4 July 2018 09:00 - 10:00 Forum Plenary session VII10:00 - 10:30 Break10:30 - 12:00 Parallel session X E103

S10.1 The technical revolutions ahead of us NGS, proteomics, Crispr-cas

Forum S10.3 ISHAM-EFISGsymposium: From non-responder to fungal breakthrough infections by opportunistic yeasts and molds

E102 S10.4 Ecology and outbreaks

E104 S10.5 Closing the mycetoma knowledge gap

E107 S10.6 Fungal respiratory infections in Cystic Fibrosis

E108 S10.7 Candida auris

E106 S10.2 ISHAM Working Group: Fungal PCR Initiative

12.00 - 12.30 Forum Closing ceremony

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Index

· Introduction Scientific program 1

· Program

Saturday 30 June 2018 4

Sunday 1 July 2018 9

Monday 2 July 2018 19

Tuesday 3 July 2018 27

Wednesday 4 July 2018 37

· E-Posters & Poster Pitch Presentations 42

· Social Program 64

· General information 68

· Sponsored integrated symposia 70

· Sponsors and exhibitors 71

· Floorplan 72

INTRODUCTION TO THE SCIENTIFIC PROGRAMPlenary sessionsNo session will be held in parallel to these sessions.Plenary sessions are indicated by the prefix: PS Parallel sessionsThese sessions are composed by conveners on specific topics to be recognized on different colors:- Fundamental: green - Clinical: red- Translational: pink- Special interest working groups: blue

Parallel sessions are indicated by the prefix: S

1

INTR

OD

UCT

ION INTRODUCTION

Dear Colleagues and Friends,

It is our great pleasure to extend a warm welcome to all of you to the Netherlands and to the 20th Congress of the International Society for Human and Animal Mycology (ISHAM).

ISHAM 2018 aims to provide clinicians, scientists and students an exciting opportunity to meet at an international forum dedicated solely to the study of medical mycology. Many colleagues from all over the world will be joining us including many young scientists and students. We are proud to host such an important meeting in our country. The Netherlands has a strong track record in mycology with leading scientists at the Center of Expertise in Mycology RadboudUMC/CWZ in Nijmegen, the Westerdijk Fungal Biodiversity Institute (former CBS) in Utrecht, and many others.

Together with the scientific committee, we have done our best to put together a strong and attractive scientific program spanning all hot topics in basic, translational and clinical mycology. We hope that you will find the meeting rewarding and that you will enjoy your stay in our capital city, Amsterdam, which is a place of many inspiring and surprising faces. No other city mixes cosmopolitan style and relaxed atmosphere quite like Amsterdam where our hospitable nature attracts an excitingly diverse population.

We wish you an enriching congress and an excellent stay in Amsterdam.

The organizing committee Paul E. Verweij, Congress President Ferry Hagen, TreasurerJacques F. Meis, Vice-president Sybren de Hoog, Chair Scientific Committee

Dear Delegates,

The ISHAM Congress fulfils our mission of education and sharing the latest research and discussion across a wide spectrum of topics in medical mycology. This Congress will be no exception. I welcome all of you and hope that this Congress will serve as a catalyst for strengthening international collaboration. On behalf of the ISHAM council I would like to thank everyone who has been involved in organising this event, and our industrial partners.

Best wishes, Malcolm RichardsonISHAM President

Saturday 30 June 201808:30 - 15:30 Young ISHAM symposium12:30 Registration Open16:00 - 17:30 Opening ceremony17:30 - 19:00 Welcome reception

Sunday 1 July 2018 Fundamental Clinical Translational Special Interest Working Groups

08:00 - 09:00 Forum General Assembly ISHAM09:00 - 10:00 Forum Plenary session I10:00 - 10:30 Break10:30 - 12:00

Parallel session I

E103 S1.1 Basic mechanisms of antifungal immunity

Forum S1.2 Mycotic keratitis

E102 S1.3 The Mycobiome in Health and Disease

E104 S1.4 Chromoblastomycosis: the role of immunity

E107 S1.5 EFISG/ECMM Aspergillus guidelines

E108 S1.6 ISHAM Working Group: Genotyping of Cryptococcus

12:00 - 13:30 Lunch break 12:15 - 13:15 Ruby lounge Poster Pitch session I12:30 - 13:30 Forum Sponsored symposium13:30 - 14:30 Forum Plenary session II14:30 - 15:00 Break15:00 - 16:30 Parallel session II E103

S2.1 Nutrition and stress

Forum S2.2 Candida auris

E102 S2.3 Antifungal stewardship

E104 S2.4 Global epidemiology & One Health of Aspergillus fumigatus

E107 S2.5 CLSI & EUCAST

E108 S2.6 ISHAM Working Group: Medical Phycology

16:30 - 18:00 Parallel session III E103 S3.1 Evolutionary strategies of fungal pathogens

Forum S3.2 AIDS-related mycoses

E102 S3.3 Indoor fungi and sick buildings

E104 S3.4 ISHAM Working Group: Veterinary Mycology

E107 S3.5 Pneumocystis

E108 S3.6 Late breakers

E105 S3.7 Behind the scene of scientific publising

18:00 - 19:00 Ruby Lounge Poster Pitch session II

Monday 2 July 2018 09:00 - 10:00 Forum Plenary session III10:00 - 10:30 Break10:30 - 12:00 Parallel sessions IV E103

S4.1 Molecular and cell biology of fungal pathogens

Forum S4.2 Cryptococcal meningitis clinical trials

E102 S4.3 Antifungals Pipeline session

E104 S4.4 Invasive infections in Asia

E107 S4.5 New insights in the management of invasive fungal disease in haematology

E108 S4.6 MMCR case report session

12:00 - 13:30 Lunch Break 12:15 - 13:15 Ruby Lounge Poster Pitch session III13:30 - 14:30 Forum Plenary session IV14:30 - 15:00 Break15:00 - 16:30 Parallel session V E103

S5.1 Hot topics in Taxonomy – Can we define fungal species borders?

Forum S5.2 Superficial dermatophytes

E102 S5.3 Beyond antifungal / host directed therapy

E104 S5.4 Mucoralean infections

E107 S5.5 From Basic Science to Patient Care

E108 S5.6 ISHAM Working Group: Fusarium

16:30 - 18:00 Parallel session VI E103 S6.1 Functional genomics and systems biology

Forum S6.2 ABPA

E102 S6.3 Tropical implantation diseases

E104 S6.4 Aspergillus terreus frontline

E107 S6.5 Malassezia in humans and animals

E108 S6.6 Surveillance azole resistance

18:00 - 20:00 Ruby Lounge Poster Pitch session IV19:00 Young ISHAM Beachparty

Tuesday 3 July 2018 09:00 - 10:00 Forum Plenary session V10:00 - 10:30 Break10:30 - 12:00 Parallel session VII E103

S7.1 Fungal biofilms Forum S7.3 The Real Pathogens: Ajellomycetaceae

E102 S7.4 Why do patients get aspergillosis?

E104 S7.5 Scedosporium

E107 S7.6 ISHAM Working Group: Sporothrix

E108 S7.7 Pediatrics

E106 S7.2 Fungal Interactions with Epithelium Trigger Innate Immune Activation

12.00 - 13.30 Lunch break12:15 - 13:00 Ruby Lounge Poster Pitch session V13:30 - 14:30 Forum Plenary session VI14:30 - 15:00 Break15:00 - 16:30 Parallel session VIII E103

S8.1 Host-pathogen interactions - the pathogen perspective

Forum S8.3 Management of fungal resistance

E102 S8.4 DNA Barcoding

E104 S8.5 Challenges in mucosal and invasive candidiasis

E107 S8.6 ECMM Educational Symposium

E108 S8.7 New developments in dermatomycosis

E106 S8.2 Milestones in medical mycology: history in modern light

16:30 - 18.00 Parallel sessions IX E103 S9.1 Genotyping in the NGS era

Forum S9.3 Dosing antifungal from the XXS to XXXL

E102 S9.4 MALDI-TOF in filamentous fungi

E104 S9.5 Recent advances in diagnosing aspergillosis

E108 S9.7 Cryptococcus-host interactions

E106 S9.2 Developments in Chinese medical mycology

18:00 Congress Dinner

Wednesday 4 July 2018 09:00 - 10:00 Forum Plenary session VII10:00 - 10:30 Break10:30 - 12:00 Parallel session X E103

S10.1 The technical revolutions ahead of us NGS, proteomics, Crispr-cas

Forum S10.3 ISHAM-EFISGsymposium: From non-responder to fungal breakthrough infections by opportunistic yeasts and molds

E102 S10.4 Ecology and outbreaks

E104 S10.5 Closing the mycetoma knowledge gap

E107 S10.6 Fungal respiratory infections in Cystic Fibrosis

E108 S10.7 Candida auris

E106 S10.2 ISHAM Working Group: Fungal PCR Initiative

12.00 - 12.30 Forum Closing ceremony

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SATURDAY 30 JUNE 2018

E-Posters & Poster Pitch SessionsPosters are submitted electronically and can be retrieved as electronic posters (e-posters) on poster terminals that will be available during the entire congress. Posters and abstracts can be found in the congress App and in the digital abstract supplement of the journal Medical Mycology, see www.ISHAM2018.org The Poster Pitch Sessions will be held at the poster terminals in the Ruby Lounge.Selected posters will be discussed during the Poster Pitch Sessions. These sessions will have a specific common thematic focus and therefore will give you the opportunity to meet colleagues from other countries working in the same field of interest. The sessions will be guided by experts in the field. After the session there will be opportunity for further discussion. Sunday 1 July 12:15 - 13:15 hrs. Sunday 1 July 18:00 - 19:00 hrs. Monday 2 July 12:15 - 13:15 hrs.Monday 2 July 18:00 - 19:00 hrs.Tuesday 3 July 12:15 - 13:15 hrs.

Information for speakersThe meeting rooms are equipped with a data projector. Please bring your presentation onmemory stick to Speaker Slide Center room E001 latest in the break before the start of your session. Technicians will assist you loading your presentation. It is not allowed to useyour own laptop. Please make sure your presentation is suitable for Microsoft PC (noMacintosh). The conference program is very tight, with not much free time betweensessions. Please respect the allotted time for presentation to ensure that your sessionstays on track. Arrive at the meeting room ten minutes before the session starts. Becomefamiliar with the operation of the audiovisual equipment. Greet the chairs who willexplain how they would like to run the session. Information for session chairs / convenersThank you for accepting to chair a session. Your contribution is veryimportant to ensure that sessions run smoothly, and to stimulate discussion.The conference program is very tight, with not much free time between sessions.Part of your contribution as a chair will be to ensure that your session stays on track.We kindly ask you to arrive in the room ten minutes before the session starts tobecome familiar with the operation of the audiovisual equipment. Please explain to thepresenters how you would like to run the session. The presenters are asked to bringtheir presentation on memory stick to the speaker slide center, latest in the breakbefore the start of the session. Technicians will assist chairs and presenters inthe meeting room. It is not allowed to use own laptops.

SATU

RDAY

Saturday 30 June 2018

Young ISHAM symposium

09:00 – 15:30 Young ISHAM symposium Forum

09:00 Opening Ferry Hagen, the Netherlands & Marcus Teixeira, USA

09:10 Lecture senior scientist Chair: Marcus Teixeira, USA Speaker: John Rex, United Kingdom

09:50 – 11:00 Young ISHAM presentations Chair: Ferry Hagen, the Netherlands

09:50 Newest Kid on the Block: Characterization of the novel multidrug-resistant pathogen, Candida auris

Tejas Bouklas, USA09:58 Chromoblastomycosis and sporotrichosis in Madagascar: an

update on epidemiology, clinical presentation and molecular diagnosis

Tahinamandranto Rasamoelina, Madagascar10:06 Recognition of DHN-melanin by the C-type lectin, MelLec, is

required for protective immunity to Aspergillus fumigatus Mark Stappers, United Kingdom10:14 Using Whole-Genome Sequencing to Identify Recent Introductions

and Track the Spread of Candida auris in the United States Nancy Chow, USA10:22 Genomic perspective of triazole resistance in Aspergillus

fumigatus| isolates without cyp51A mutations using Whole-Genome Sequencing

Cheshta Sharma, India10:30 The mitochondria-associated J-domain protein Dnj1 is required

for virulence in the fungal pathogen Cryptococcus neoformans Linda Horianopoulos, Canada

10:40 – 11:00 Coffee break Forum & Ruby Lounge

11:00 – 11:45 The benefits of scientific mobility and international collaboration

Chair: Marcus Teixeira, USA Speakers: Radamés Cordero, USA

11:45 – 12:45 Young ISHAM presentations Chairs: Ana Alastruey-Izquierdo, Spain & Leonardo Nimrichter, Brazil

11:30 Generation and characterization of Candida parapsilosis over expression mutant strains

Sara Pál, Hungary11:38 The vacuolar sorting protein Vps45 links iron uptake,

mitochondrial function and virulence in the pathogenic fungus Cryptococcus neoformans

Mélissa Caza, Canada11:46 Novel FK506 analog exhibits anti-fungal activity against

Cryptococcus neoformans in vitro and in an animal model Michael Hoy, USA11:54 New insights into the Cryptococcus neoformans capsule structure Radamés Cordero, USA12:02 Pantothenic acid improves culturability of dormant Cryptococcus

neoformans Benjamin Hommel, France12:10 Magnetic resonance imaging of infected mouse brains allows

non- invasive screening of differences in the virulence of clinical Cryptococcus neoformans strains

Liesbeth Vanherp, Belgium12:18 Whole genome sequencing of P. brasiliensis isolates of endemic

areas in Argentina and Paraguay Maria Cattana, Argentina

12:26 – 13:15 LunchForum & Ruby Lounge

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SATU

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6

ISHAM CONGRESS

16:00 WelcomeForum & Local Organising Committee Ruby Lounge Paul E. Verweij, Congress President

16.15 Welcome from the President of ISHAM and ISHAM Awards: Malcolm Richardson, ISHAM President Lucille George Award

Jack Edwards (Clinical) David Ellis (Basic Science)

ISHAM Young Investigator Awards: The fungi on sinonasal mucosa: normal content or silent threat? Aleksandra Barac, Belgrade, Serbia (Clinical) Counteracting nutritional immunity – micronutrient scavenging by human

fungal pathogens Duncan Wilson, Aberdeen, United Kingdom (Basic Science)

16:35 Opening lecture - Biodesign: From Inspiration to Integration Rosa Kieft, the Netherlands

17:30 – 19:00 Welcome receptionForum & Ruby Lounge

19:00 – 21:00 ISHAM/ECMM/GAFFI Outreach Evening Latin America and E106 South USA This evening program is only accessible for invited delegates

13:15 – 14:45 Young ISHAM presentations Chairs: Ferry Hagen, the Netherlands & Giuseppe Ianiri, USA

13:15 A prospective multi-centre study on mucormycosis in India: epidemiology, diagnosis and treatment

Hariprasath Prakash, India13:23 Eradication of fungi from sinuses helps in improvement of lower

respiratory tract’s clinical symptoms in children with cystic fibrosis Aleksandra Barac, Serbia

13:31 Mycobiome of Bondi Beach Sand Terre Darcii, Australia13:39 Evaluation of a Histoplasma antigen Lateral Flow Assay for the

rapid diagnosis of progressive disseminated histoplasmosis in Persons Living with HIV and aids

Diego Caceres, USA13:47 Alternative mechanisms of protection of Aspergillus fumigatus

conidia against Reactive Oxygen Species Esther Keizer, the Netherlands13:55 Cryptococcal meningitis is associated with vitamin D deficiency in

HIV-infected Zimbabwean adults Tinashe Nyazika, Malawi14:03 A new receptor is involved in the uptake of Sporothrix spp.

by human macrophages Gabriela Neves, Brazil14:11 Establishment and optimization of a combined MLST scheme

for Pneumocystis jirovecii Lana Pasic, Australia14:19 Orchestration of chitin synthesis at the septation site of Candida

albicans Maria Spyrou, United Kingdom

14:30 – 15:15 Lecture senior scientist Chair: Marcus Teixeira, USA Speakers: Karl Clemons, USA & Peter Donnelly, the Netherlands

15:15 – 15:30 The Dr. Ira. F. Salkin Memorial Award + Closure Karl Clemons, USA & Marcus Teixeira, USA

7

SUNDAY 1 JULY 2018

8

Sunday 1 July 2018

08:00 - 09:00 General Assembly ISHAMForum

09:00 - 10:00 PS1 Presidential address Forum Chair: Malcolm Richardson, United Kingdom Arunaloke Chakrabarti, India

10:00 - 10:30 Coffee break Forum & Ruby lounge

10:30 - 12:00 Parallel session I

S1.1 Basic mechanisms of antifungal immunityE103 Convener: Mihalis Lionakis, USA

10:30 S1.1a Basic mechanisms of antifungal immunity Mihalis Lionakis, USA10:55 S1.1b Protection and pathology in pulmonary aspergillosis Luigina Romani, Italy11:20 S1.1c Protective immune responses during cryptococcosis Carolina Coelho, USA11:45 S1.1d Evolution of Candida albicans colonization and anti-Candida

innate and adaptive immunity in patients having undergone surgical resection for Crohn’s disease

Daniel Poulain, France

S1.2 Mycotic keratitisForum Convener: Lalitha Prajna, India

10:30 S1.2a Update and epidemiology of mycotic infections of the eye Lalitha Prajna, India10:55 S1.2b Molecular characterization, diagnosis and antifungal susceptibility

patterns of clinically relevant Fusarium species Abdullah Al-Hatmi, Oman11:20 S1.2c Two Aspergillus species, A. flavus and A. fumigatus –

a comparative study of their conidial surface properties and immunological reactivities

Vishukumar Aimanianda, France11:45 S1.2d Fungal keratitis in The Netherlands Claudy Oliveira dos Santos, the Netherlands

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10

11:20 S1.5c Children are not small adults: Management of invasive aspergillosis in pediatric patients

Andreas Groll, Germany11:45 S1.5d How to properly diagnose invasive aspergillosis? /

Recommendations on mycologic diagnosis of invasive aspergillosis

Cornelia Lass-Flörl, Austria

S1.6 ISHAM Working Group: Genotyping of Cryptococcus E108 Convener: Massimo Cogliati, Italy

10:30 S1.6a Cryptococcus neoformans and C. gattii species complex genotypes in China

Meng Xiao, China 10:55 S1.6b Genotypes of Cryptococcus neoformans and C. gattii species

complex in Europe Massimo Cogliati, Italy11:20 S1.6c Molecular epidemiology of Cryptococcus in South Africa Serisha Naicker, South Africa11:45 S1.6d Molecular epidemiology of Cryptococcus neoformans and Cryptococcus gattii in Latin America Carolina Firacative, Colombia

12:00 - 13:30 Lunch breakForum & Ruby Lounge

12:15 – 13:15 Poster Pitch session I Ruby Lounge View the full program on page 42

12:30 – 13:30 Sponsored symposium Forum Please see page 70 for more information about the program.

13:30 – 14:30 PS2 WHO is afraid of fungus Forum Chair: Jacques Meis, the Netherlands Carmem Pessoa Silva, Switzerland

14:30 – 15:00 Coffee breakForum & Ruby Lounge

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S1.3 The Mycobiome in Health and Disease E102 Convener: Mahmoud Ghannoum, USA

10:30 S1.3a Mycobiome and Bacteriome Interactions: vital key of health and disease

Mahmoud Ghannoum, USA10:55 S1.3b Fungal feelings in the Irritable Bowel Syndrome René van den Wijngaard, the Netherlands11:20 S1.3c The Mycobiota: Interactions between Commensal Fungi and the

Host David Underhill, USA11:45 S1.3d Gastrointestinal microbiota alteration Induced by Mucor

circinelloides in a murine model Soo Chan Lee, USA S1.4 Chromoblastomycosis: the role of immunityE104 Convener: Peiying Feng, China

10:30 S1.4a Development of immunomodulators as adjuvant in treatment of experimental chromoblastomycosis caused by Fonseca pedrosoi

Anamelia Bocca, Brazil10:55 S1.4b Transformation into muriform cells links to refractory murine

chromoblastomycosis due to F. pedrosoi involving a chitin-induced impairment of IFN-gamma production

Bilin Dong, China11:20 S1.4c MelLec: A new receptor for melanised fungi Gordon Brown, United Kingdom11:45 S1.4d Chromoblastomycosis and sporotrichosis in Madagascar: an

update on epidemiology, clinical presentation and molecular diagnosis

Tahinamandranto Rasamoelina, Madagascar

S1.5 EFISG/ECMM Aspergillus guidelinesE107 Conveners: Sevtap Arikan, Turkey & Oliver Cornely, Germany

10:30 S1.5a Guidance in times of antifungal resistance / Current perspective for antifungal resistance in aspergillosis

Paul Verweij, the Netherlands10:55 S1.5b Chronic pulmonary aspergillosis – Focus on differences between

EU and US guidelines / Clinical guidelines for chronic pulmonary aspergillosis

David Denning, United Kingdom

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S2.4 Global epidemiology & One Health of Aspergillus fumigatusE104 Conveners: Paul Verweij, the Netherlands & Katrien Lagrou, Belgium

15:00 S2.4a Triazole resistance mechanisms in A. fumigatus: what do we learn from full genome sequencing

Matthew Fisher, United Kingdom15:25 S2.4b Evolving epidemiology and spread of azole resistance in A. fumigatus Eveline Snelders, the Netherlands15:50 S2.4c Role of agricultural pesticide use in the evolution of triazole

resistance in fungi Bart Fraaije, United Kingdom16:15 S2.4d Azole resistance in Aspergillus fumigatus: Screening in Cystic

Fibrosis patients Steffi Rocchi, France

S2.5 CLSI & EUCASTE107 Convener: Maiken Arendrup, Denmark

15:00 S2.5a Methods for mould testing for everyone or for special ones? Joseph Meletiadis, Greece15:25 S2.5b Absorbance, turbidity, diameter, Oh my! Harmonizing disparate

yeast testing methodologies Shawn Lockhart, USA15:50 S2.5c Susceptibility testing of dermatophytes, why and how? Mahmoud Ghannoum, USA16:15 S2.5d EUCAST susceptibility testing of Trichophyton rubrum:

chloramphenicol and cycleheximide supplemented growth medium improve assay performance

Maiken Arendrup, Denmark

S2.6 ISHAM Working Group: Medical PhycologyE108 Convener: Koichi Makimura, Japan

15:00 S2.6a Microsporidiosis and pythiosis in Medical Field Koichi Makimura, Japan15:25 S2.6b Genetic and biological insights from whole-genome sequencing

of the pathogenic microalga Prototheca wickerhamii Tomasz Jagielski, Poland15:50 S2.6c Prototheca infection in dogs and cats Patrizia Danesi, Italy16:15 S2.6d Characterization of CYP51 gene of pathogenic algae of

Prototheca spp. Michiaki Masuda, Japan

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15:00 - 16:30 Parallel session II

S2.1 Nutrition and stressE103 Convener: Alistair Brown, United Kingdom

15:00 S2.1a Carbon metabolism, immune suppression, and virulence in Candida albicans

Slavena Vylkova, Germany15:25 S2.1b Adaptation to complex host niches by fungal pathogen

C. albicans drives resistance against neutrophil attack Constantin Urban, Sweden15:50 S2.1c Nutrient sensing and Cryptococcal virulence James Kronstad, Canada16:15 S2.1d Fungal Transformers: Tracking a Moving Target Delma Childers, United Kingdom

S2.2 Candida aurisForum Convener: Ana Alastruey-Izquierdo, Spain

15:00 S2.2a Identification and antifungal susceptibility of Candida auris Anuradha Chowdhary, India15:25 S2.2b Management of Candida auris outbreaks at a national level Silke Schelenz, United Kingdom 15:50 S2.2c Global Epidemiology and strategies to control the emergence of

a superbug: Candida auris Tom Chiller, USA16:15 S2.2d Skin and surface disinfection challenges for the emerging

pathogen Candida auris Ryan Kean, United Kingdom

S2.3 Antifungal stewardshipE102 Convener: Martin Hönigl, Austria

15:00 S2.3a Azole prophylaxis: Cost-effective strategies and money wasters Jürgen Prattes, Austria 15:25 S2.3b Echinocandins in patients with hematologic malignancies:

Indications, dosage, costs and outcome Werner Heinz, Germany15:50 S2.3c Emerging diagnostics for invasive mould infections and

diagnostic driven treatment strategies Sophia Koo, USA 16:15 S2.3d Impact of infectious diseases consultation on mortality in patients

with candidemia Andrej Spec, USA

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17:20 S3.3c Immunodeficiencies associated with indoor mold exposures and persistent illness, and available immune therapies

Irene Grant, USA17:45 S3.3d Aspergillus ochraceus: a potential fungal allergen Sara Gago, United Kingdom

S3.4 ISHAM Working Group: Veterinary MycologyE104 Conveners: Amir Seyedmousavi, USA & Jacques Guillot, France

16:30 S3.4a Batrachochytrium salamandrivorans infections in amphibians Ann Martel, Belgium16:55 S3.4b Cryptic species, cats and aspergillosis Vanessa Barrs, Australia17:20 S3.4c Trichophyton benhamiae a zoonotic fungal pathogen Vit Hubka, Czech Republic17:45 S3.4d The serial killer Saprolegnia – biofilm formation and combat

strategies Ida Skaar, Norway

S3.5 PneumocystisE107 Convener: Alexandre Alanio, France

16:30 S3.5a Is Pneumocystis jirovecii a commensal of the respiratory tract of humans? Sergio Vargas, Chile16:55 S3.5b Pneumocystis species in mammals: how different are they? Patrizia Danesi, Italy 17:20 S3.5c Pneumocystis jirovecii detection in asymptomatic patients: what

does its natural history tell us? Alexandre Alanio, France17:45 S3.5d Pneumocystis jirovecii colonization in pregnant women Alejandra Calderón Hernández, Spain

S3.6 Late breakers E108 Chair: Judith Berman, Israel

16:30 S3.6a Human and veterinary blastomycosis caused by Blastomyces helicus and B. percursus identified among global fungal collections Ilan Schwarz, Canada

16:45 S3.6b Identification of a potent HIV latency reversal agent from a screen of secondary fungal metabolites Tokameh Mahmoudi, the Netherlands

16:30 – 18:00 Parallel session III

S3.1 Evolutionary strategies of fungal pathogensE103 Convener: Eveline Snelders, the Netherlands

16:30 S3.1a Genome evolution in Candida albicans Richard Bennet, USA16:55 S3.1b Sexual reproduction and the evolution of eukaryotic microbial

pathogens Joseph Heitman, USA17:20 S3.1c Understanding the role of the natural life history of Aspergillus

fumigatus in azole resistance development Bas Zwaan, the Netherlands17:45 S3.1d Genome sequencing reveals infection mechanisms for two

amphibian infecting chytrid species Rhys Farrer, United Kingdom

S3.2 AIDS-related mycosesForum Conveners: Darius Armstrong James, United Kingdom &

Vishnu Chaturvedi, USA

16:30 S3.2a Host recognition and clearance of Pneumocystis: Investigating immune mediators and mechanisms

Claire Hoving, South Africa16:55 S3.2b AIDS-related histoplasmosis in Latin America Antoine Adenis, French Guyana17:20 S3.2c AIDS-related mycoses in South East Asia Thuy Le, USA17:45 S3.3d Talaromyces spp., new emerging pathogen in Jakarta, Indonesia:

Analyses of clinical and animal isolates Sem Samuel Surja, Indonesia

S3.3 Indoor fungi and sick buildingsE102 Conveners: Jos Houbraken, the Netherlands & Irene Grant, USA

16:30 S3.3a Clinical Findings After Hazardous Indoor Microfungal Trichothecenes Mycotoxin Exposure: Disability outcomes risk analysis, immunosuppression and impaired genetic MTHFR detoxification status

Irene Grant, USA16:55 S3.3b Chronic pain, indoor mold exposure, mycotoxin excretion, and

response to antifungal therapy James Dillard, USA

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Speakers: • Oliver Cornely, Germany - EiC – Mycoses • Christophe Hennequin, France - EiC- J Mycologie Medicale, • Guillermo Quindos, Spain - EiC - Revista Iberoamericana de

Micología • Oliver Kurzai, Germany – EiC - Medical Mycology Case Reports • Vishnu Chaturvedi, USA – EiC - Mycopathologia • Karl V. Clemons, USA – EiC - Medical Mycology

18:00 – 19:00 Poster Pitch session II Ruby Lounge View the full program on page 47

19:00 – 21:00 ISHAM/ECMM/GAFFI Outreach Evening Africa, Japan E106 and China This evening program is only accessible for invited delegates.

17:00 S3.6c Invasive deep dermatophytosis associated with CARD 9 immunodeficiency successfully treated with allogenic stem cell transplant-Report of two cases Flavio Queiroz Telles, Brazil

17:15 S3.6d Influenza-associated aspergillosis: is there a place for antifungal prophylaxis Joost Wauters, Belgium

17:30 S3.6e Emergence of clinical and mycological resistance in T. interdigitale infections in North India Ashutosh Singh, India

17:45 3.6f Managing the introduction of Candida auris into the UK Colin Brown, USA

S3.7 Behind the scene of scientific publishingE105 Moderators: Vishnu Chaturvedi, USA & Karl Clemons, USA This will be an interactive session between the participants who

are all the editor in chief of a journal, which publishes papers on fungi and fungal infections. Participants will give an overview of the workings of their journal for the editorial process and resources available to prospective authors. In addition, the participants will offer their thoughts on the future directions of publication. The audience will be able to ask questions and obtain the opinions of these experts on any of the topics pertaining to publication of scientific studies.

Session highlights: • Introduce the history and current focus of each journal • Value of citation indices and other evaluations of your journal? • Author resources provided by the publisher • How the papers are assessed initially, how editorial and review

decisions are made, and what leads to a rejection? • What to do if a paper is rejected? • Open access, publication charges, plagiarism, and other topics • How young scientists can participate as future reviewers and

editors? • Online only or print or hybrid models, and the future direction of

publishing • Ask an editor?’ (Audience interactions)

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Monday 2 July 2018

09:00 – 10:00 PS3 Translational mycology / From laboratory discovery toForum patient care Donald Sheppard, Canada

10:00 – 10:30 Coffee break Forum & Ruby Lounge

10:30 – 12:00 Parallel session IV

S4.1 Molecular and cell biology of fungal pathogensE103 Convener: Neil Gow, United Kingdom

10:30 S4.1a The cell biology of cell walls of fungal pathogens and the interaction with immune cells

Neil Gow, United Kingdom10:55 S4.1b Cell biology and structure of the Candida cell wall Megan Lenardon, Australia11:20 S4.1c Haploid Candida albicans as a powerful tool for new discoveries Yue Wang, Singapore 11:45 S4.1d Dysfunction in complex I of Candida albicans influences the

phagocytosis and killing ability of macrophage and colonization in mice intestine

Xiaodong She, China

S4.2 Cryptococcal meningitis clinical trialsForum Convener: Tihana Bicanic, United Kingdom

10:30 S4.2a ACTA and beyond Thomas Harrison, United Kingdom10:55 S4.2b New and novel agents for prevention of cryptococcal disease David Boulware, USA11:20 S4.2c AmBition-CM: High dose Liposomal Amphotericin for HIV related

cryptococcal meningitis William Hope, United Kingdom 11:45 S4.2d Dynamic ploidy changes drive emergence of fluconazole

resistance in human cryptococcal meningitis Neil Stone, United Kingdom

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S4.6 MMCR case report session E108 Conveners: Oliver Kurzai, Germany & Katrien Lagrou, Belgium

10:30 S4.6a Case 1 Shivaprakash Rudramurthy, India 10:55 S4.6b Case 2 Jochem Buil, the Netherlands 11:20 S.4.6c Case 3 Rachel Caligiorne, Brazil11:45 Discussion

12:00 – 13:30 Lunch break Forum & Ruby Lounge

12:15 – 13:15 Poster Pitch session IIIRuby Lounge View the full program on page 51

13:30 – 14:30 PS4 Clinically validation and implementation of next generationForum sequencing into a clinical laboratory for patient care testing Chair: Ferry Hagen, the Netherlands Sean Zhang, USA

14:30 – 15:00 Coffee break Forum & Ruby Lounge

15:00 – 16:30 Parallel session V S5.1 Hot topics in Taxonomy - Can we define fungal species borders? E103 Convener: June Kwon-Chung, USA

15:00 S5.1a Viewing species complexes through a phylogenomic lens – the Curious Case of Cryptococcus

David Engelthaler, USA15:25 S5.1b What should be the ideal criteria for species delimitation in

pathogenic fungi? John Taylor, USA15:50 S5.1c Mitochondrial genomes and species boundaries in the genus

Fusarium Balász Brankovics, the Netherlands16:15 S5.1d Evolution of virulence genes and cryptic speciation in the fungal

pathogen Histoplasma Victoria Sepúlveda, USA

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S4.3 Antifungals Pipeline session E102 Chair: Roger Brüggeman, the Netherlands

10:30 S4.3a CD101 – Cidara Taylor Sandison, USA 10:50 S4.3b F901318 - F2G John Rex, United Kingdom11:10 S4.3c SCY-078 – Scynexis David Angulo, USA 11:30 S4.4d VT-1598 – Viamet Edward Garvey, USA 11:40 Discussion

S4.4 Invasive infections in AsiaE104 Conveners: Arunaloke Chakrabarti, India & Ruo-yu Li, China

10:30 S4.4a The unique features and challenges of yeast infections in Asia: focus on Candida tropicalis

Yee-Chun Chen, Taiwan10:55 S4.4b Black mycelial fungal infection with special reference t Cladophialophora bantiana Asian perspectives Retno Wahyuningsih, Indonesia11:20 S4.4c How to guard the mimic fungal infection in Asia? Ariya Chindamporn, Thailand11:45 S4.4d Fereydounia khargensis, an emerging Ustilaginomycetous

opportunistic yeast, and antifungal resistances Ratna Mohd tap, Malaysia

S4.5 New insights in the management of invasive fungal disease E107 haematology Convener: Peter Donnelly, the Netherlands

10:30 S4.5a Invasive aspergillosis: New risk groups Livio Pagano, Italy10:55 S4.5b New management strategies (EORTC study) Peter Donnelly, the Netherlands11:20 S4.5c New antifungals (isavuconazole, new formulations of

posaconazole, drugs in the pipeline) Johan Maertens, Belgium 11:45 S4.5d New guidelines (ECCMID Aspergillus, IDSA Aspergillus and ECIL2017) Fanny Lanternier, France

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S5.5 From Basic Science to Patient Care E107 Convener: Dieter Buchheidt (DMykG) & Jacques Meis, the Netherlands

15:00 S5.5a Translating antifungal immunology into patient care Frank van de Veerdonk, the Netherlands15:25 S5.5b Translating mycology into patient care Oliver Kurzai, Germany15:50 S5.5c Clinical challenges in the management of invasive fungal infections Andreas Groll, Germany16:15 S5.6d Candida auris: understanding the mechanisms of host immune

response Mariolina Bruno, the Netherlands

S5.6 ISHAM Working Group: FusariumE108 Conveners: Anne van Diepeningen & Abdullah Al-Hatmi, Oman

15:00 S5.6a The trans-kingdom pathogen Fusarium Anne van Diepeningen, the Netherlands15:25 S5.6b Fusarium keratitis: the species and their occurrence Grit Walther, Germany15:50 S5.6c Intrinsic resistance to antifungals Joseph Meletiadis, Greece16:15 S5.6d Histological characterization and host response during Fusarium

solani infection in an ex-vivo human skin model Dora Corzo-Leon, United Kingdom

16:30 – 18:00 Parallel session VI

S6.1 Functional genomics and systems biologyE103 Convener: Berhard Hube, Germany

S6.1a QPCR detection of Mucorales DNA in bronchoalveolar lavage fluid for pulmonary mucormycosis diagnosis

Laurence Millon, France S6.1b Antifungal tolerance is a subpopulation effect distinct from

resistance and is associated with persistent candidemia Judith Berman, Israel S6.1c Functional genomics of Candida species Geraldine Butler, Ireland S6.1d Comparative genomics for understanding the development of

multidrug resistance in Candida lusitaniae Dominique Sanglard, SwitzerlandM

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S5.2 Superficial dermatophytesForum Conveners: Ryoji Tsuboi, Japan & Ruoyu Li, China

15:00 S5.2a Epidemiology and clinical implication of dermatophytes and nondermatophytes in South East Asia Sumanas Bunyaratavej & Charussri Leeyaphan, Thailand15:25 S5.2b Cutaneous infection by zoonotic dermatophytes: an update Pei-lun Sun, Taiwan15:50 S5.2c Molecular epidemiology of dermatophytoses Mochizuki Takashi, Japan16:15 S5.2d New oral and topical treatments for onychomycosis Ryoji Tsuboi, Japan

S5.3 Beyond antifungal / host directed therapyE102 Convener: Mihai Netea, the Netherlands

15:00 S5.3a Host-directed therapy in candidemia Mihai Netea, the Netherlands15:25 S5.3b New insights in diagnosis and immunopathology of aspergillosis Agostinho Carvalho, Portugal 15:50 S5.3c New insights in Cryptococcus infections Robin May, United Kingdom16:15 S5.3d Quantifying host-pathogen interaction in blood from patients

with selected immunodeficiencies Kerstin Hünniger, Germany

S5.4 Mucoralean infectionsE104 Convener: Anna Skiada, Greece

15:00 S5.4a Managing mucormycosis: why is it so difficult? Ashraf Ibrahim, USA15:25 S5.4b Diagnostics: From histopathology and cultures to qPCR and Birgit Willinger, Austria15:50 S5.4c Challenging Cases of Mucormycosis Rajeev Soman, India16:15 S5.4d Mucormycosis in patients with hematological diseases after

hematopoietic stem cell transplantation and chemotherapy Yuliya Rogacheva, Russia

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S6.5 Malassezia in humans and animalsE107 Conveners: Jacques Guillot, France & Teun Boekhout,

the Netherlands

16:30 S6.5a Analysis of Malassezia microbiota in humans and animals: does it really help us to better understand and control Malassezia-related diseases?

Jacques Guillot, France16:55 S6.5b The human skin microbiome: cause or effect? The role of

Malassezia in human skin health and disease Thomas Dawson, Singapore17:20 S6.5c The overgrowth of Malassezia spp. in canine atopic dermatitis

– the reason or the result of disease? Bozena Dworecka-Kaszak, Poland17:45 S6.5d Characterization of growth of lipid-dependent Malassezia yeast

species, members of the skin mycobiome Hans de Cock, the Netherlands

S6.6 Surveillance azole resistanceE108 Convener: Jacques Meis, the Netherlands

16:30 S6.6a Surveillance of azole resistance in Colombia Patrice le Pape, France16:55 S6.6b Surveillance and status quo of azole resistant Aspergillus in

East Asia Chi-Jung Wu, Taiwan 17:20 S6.6c First report of azole-resistant Aspergillus fumigatus harbouring TR34/L98H and M220R in Brazil Laura Bedin Denardi, Brazil17:45 S6.6d Status and Surveillance of Azole Resistance in North America Elizabeth Berkow, USA

18:00 – 19:00 Poster Pitch session IVRuby Lounge View the full program on page 55

19:00 – 00:30 Young ISHAM Beach Party More information is available on page 64

19:00 – 21:00 ISHAM/ECMM/GAFFI Outreach Evening Eastern Europe E106 This evening program is only accessible for invited delegates

S6.2 ABPAForum Convener: Ritesh Agarwal, India

16:30 S6.2a Recent advances in allergic bronchopulmonary aspergillosis complicating asthma Arunaloke Chakrabarti, India16:55 S6.2b Severe asthma with fungal sensitization David Denning, United Kingdom17:20 S6.2c Recent advances in allergic bronchopulmonary aspergillosis

cystic fibrosis Richard Moss, USA17:45 S6.2d A new Aspergillus fumigatus Western Blot assay for IgE

sensitization and Allergic Broncho Pulmonary Aspergillosis diagnosis

Raphael Piarroux, France

S6.3 Tropical implantation diseasesE102 Convener: Flavio Queiroz-Telles, Brazil

16:30 S6.3a Management of chromoblastomycosis: difficulties, challenges and perspectives in developing countries

Lala Soavina Ramarozatovo, Madagascar16:55 S6.3b The expanding cat-transmitted sporotrichosis in Brazil Anderson Rodrigues, Brazil 17:20 S6.3c Diversity among coelomycetous isolates from cutaneous and

subcutaneous infections Dea Garcia-Hermoso, France17:45 S6.3d Conidiobolomycosis: presentation of two cases in adult and

infant Alexandro Bonifaz, Mexico

S6.4 Aspergillus terreus frontlineE104 Convener: Cornelia Lass-Flörl, Austria

16:30 S6.4a The Aspergillus terreus species complex: What is new Jesus Guinea, Spain 16:55 S6.4b Outcome and treatment of Aspergillus terreus infections Oliver Cornely, Germany17:20 S6.4c Amphotericin B resistance: New insights Cornelia Lass-Flörl, Austria17:45 S6.4d Molecular epidemiology and antifungal susceptibility profiles of Aspergillus terreus in Iran Afsane Vaezi, Iran

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Tuesday 3 july 2018

09:00 – 10:00 PS5 The evolving role of infection control in mycology Forum Chair: Paul Verweij, the Netherlands Andreas Voss, the Netherlands

10:00 – 10:30 Coffee break Forum & Ruby Lounge

10:30 – 12:00 Parallel session VII

S7.1 Fungal biofilmsE103 Convener: Gordon Ramage, United Kingdom

10:30 S7.1a Candida auris and non-albicans biofilms Gordon Ramage, United Kingdom10:55 S7.1b insights into new antibiofilm molecules Jose Lopez-Ribot, USA11:20 S7.1c Fungal-bacterial biofilms: consequences in an intra-abdominal

infection model Mairi Noverr, USA11:45 S7.1d Deciphering the global transcriptomic profile of Candida glabrata

during biofilm and planktonic growth phase Khem Raj, India

S7.2 Fungal Interactions with Epithelium Trigger Innate Immune Activation

E106 Convener: Andrew Limper, USA

10:30 S7.2a Epithelial Activation by Candida species Julian Naglik, United Kingdom 10:55 S7.2b The Immunopathogenesis of Candida vaginitis Paul Fidel, USA11:20 S7.2c Pneumocystis Activation of Innate Immune Responses by Lung

Epithelial Cells Andrew Limper, USA11:45 S7.2d Differential gene expression of Aspergillus fumigatus and

Aspergillus niger interacting with epithelial lung cells Esther Keizer, the Netherlands

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S7.6 ISHAM Working Group: SporothrixE107 Convener: Leila Lopes-Bezerra, Brazil

10:30 S7.6a RNA-seq and transcriptome-wide analysis of Sporothrix schenckii yeast and mycelial forms

Orazio Romeo, Italy10:55 S7.6b Sporothrix globosa causing sporotrichosis in Jilin Province

(Northeast of China): Prevalence, molecular characterization, and antifungal susceptibility

Shanshan Li, China11:20 S7.6c Human serum factors impact the interaction of Sporothrix spp.

With human macrophages Leila Lopes-Bezerra, Brazil11:45 S7.6d Cutaneous disseminated sporotrichosis: Clinical experience of 24

cases Alexandro Bonifaz, Mexico

S7.7 PediatricsE108 Convener: Andreas Groll, Germany

10:30 S7.7a Antifungal prophylaxis and treatment – current choices and strategies in children

Andreas Groll, Germany 10:55 S7.7b Diagnostic biomarkers and imaging – what is different in pediatrics Thomas Lehrnbecher, Germany11:20 S7.7c Epidemiology and outcome of IFD in pediatrics patients:

The Southern hemisphere Fabianne Carlesse, Brazil 11:45 S7.7d Epidemiology and outcome of IFDs in pediatrics patients:

The Northern Hemisphere Emmanuel Roilidis, Greece

12:00 – 13:30 Lunch break Forum & Ruby Lounge

12:15 – 13:15 Poster Pitch session VRuby Lounge View the full program on page 59

13:30 – 14:30 PS6 Antifungal drug discovery comes of ageForum Chair: Martin Hönigl, Austria John Rex, United Kingdom

14:30 – 15:00 Coffee break Forum & Ruby Lounge

S7.3 The Real Pathogens: AjellomycetaceaeForum Conveners: Anastasia Litvintseva, USA & Vishnu Chaturvedi, USA

10:30 S7.3a Emerging Emergomyces africanus in Africa Nelesh Govender, South Africa10:55 S7.3b Migration of Coccidioides posadasii into South America Bridget Barker, USA11:20 S7.3c Ecology and geographic distribution of Coccidioides Anastasia Litvintseva, USA11:45 S7.3d Molecular epidemiology of Colombian Histoplasma capsulatum

(Hc) isolates showed their polyphyletic behavior and indicated chicken manure as one infection source

Luisa Fernanda Gómez Londoño, Colombia

S7.4 Why do patients get aspergillosis? E102 Convener: Adilia Warris, United Kingdom

10:30 S7.4a Influenza-associated aspergillosis Frank van de Veerdonk, the Netherlands10:55 S7.4b Aspergillus-derived secreted products driving invasion of

pulmonary epithelia Elaine Bignell, United Kingdom 11:20 S7.4c Defective antifungal immunity in cystic fibrosis Adilia Warris, United Kingdom11:45 S7.4d Increased incidence of invasive aspergillosis in patients receiving

empiric carbapenem in febrile neutropenia Chai Louis, Singapore

S7.5 ScedosporiumE104 Conveners: Sharon Chen, Australia & Michaela Lackner, Austria

10:30 S7.5a Enzymatic antioxidant defense systems in Scedosporium species Jean-Philippe Bouchara, France10:55 S7.5b N-chlorotaurine, a potential agent for the topical treatment of

scedosporiosis and lomentosporiosis Michaela Lackner, Austria11:20 S7.5c Diversity within the genera Lomentospora and Scedosporium José Cano-Lira, Spain11:45 S7.5d “S.O.S.”: The Nationwide French Scedosporiosis Observational

Study (2005 2017) Franny Lanternier, France

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S8.4 DNA BarcodingE102 Convener: Wieland Meyer, Australia

15:00 S8.4a Advances is DNA barcoding of pathogenic fungi Wieland Meyer, Australia15:25 S8.4b From DNA barcoding databases to complex systems Vincent Robert, the Netherlands15:50 S8.4c Applying DNA barcoding for clinical diagnosis Gianluigi Cardinali, Italy16:15 S8.4d Improving fungal diagnosis via dual fungal DNA barcoding Minh Thuy Vi Hoang, Australia

S8.5 Challenges in mucosal and invasive candidiasisE104 Conveners: Stavroula Antonopoulou, Greece & Jesus Guinea, Spain

15:00 S8.5a Immunity to Candida vaginitis Flavia De Bernardis, Italy15:25 S8.5b Management of complicated and recurrent vulvovaginal

candidiasis Drosos Karageorgopoulos, Greece15:50 S8.5c Hidden echinicandin resistance induction due to abdominal

candida infection Cornelius Clancy, USA16:15 S8.5d Identification of Candida albicans protein kinases, involved in environmental pH modulation and biofilm formation Philipp Brandt, Germany

S8.6 ECMM Educational SymposiumE107 Conveners: Oliver Cornely, Germany & Jean-Pierre Gangneux, France * this symposium continues during parallel session IX and lasts 180 minutes.

15:00 S8.6a Challenges in the treatment of IFD in children Thomas Lernbecher, Germany15:25 S8.6b Genetic predictors of response to antifungals in IFD Michaela Lackner, Austria 15:50 S8.6c Rare fungal infections – Experience of the German National Reference Center NRZMyk Oliver Kurzai, Germany16:15 S8.6d Going steady: FungiScope, a worldwide effort in researching rare

fungal diseases Danilia Seidel, Germany

15:00 – 16:30 Parallel session VIII

S8.1 Host-pathogen interactions - the pathogen perspectiveE103 Convener: Bernhard Hube, Germany

15:00 S8.1a Interactions of Candida albicans with the host Bernhard Hube, Germany15:25 S8.1b The immunoglycobiology of fungal pathogens Héctor Mora-Montes, Mexico15:50 S8.1c The cell wall of A.fumigatus and its impact on fungal virulence Jean-Paul Latge, France16:15 S8.1d Discussion

S8.2 Milestones in medical mycology: history in modern lightE106 Convener: Luciano Polonelli, Italy

15:00 S8.2a Taxonomic benchmarks in mycotoxinogenic fungi Robert Samson, the Netherlands15:25 S8.2b Nystatin and the women who founded the antifungal era Chet Cooper, USA 15:50 S8.2c History of Cryptococcus and cryptococcosis Wanqing Liao, China 16:15 S8.2d The history of medical mycology within the ISHAM Luciano Polonelli, Italy

S8.3 Management of fungal resistanceForum Convener: Oliver Lortholary, France

15:00 S8.3a Does antifungal résistance influence the therapeutic decision during invasive candidiasis

Oliver Lortholary, France15:25 S8.3b Antifungal therapy for C parapsilosis candidemia: who are the

heroes and villains Arnaldo Colombo, Brazil15:50 S8.3c Infections with Scedosporium/Lomentospora from an Australian perspective are we at the end of the road Sharon Chen, Australia 16:15 S8.3d Voriconazole resistance and mortality in 196 Aspergillus

fumigatus culture positive patients with invasive aspergillosis Pieter Lestrade, the Netherlands

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16:55 S9.1b NGS in the era of drug resistant Aspergillus fumigatus Johanna Rhodos, United Kingdom 17:20 S9.1c NGS and typing of Candida albicans: just an improvement of

other typing methods? Christophe d’Enfert, France17:45 S9.1d Whole genome sequencing of P. brasiliensis isolates of endemic

areas in Argentina and Paraguay Maria Cattana, Argentina

S9.2 Developments in Chinese medical mycology E106 Convener: Ruoyu Li, China

16:30 S9.2a Anti–Interferon-? autoantibodies are underlie the disseminated Talaromyces marneffei infection

Cunwei Cao, China16:55 S9.2b CARD9 deficiency and dematiaceous fungal infections Xiaowen Wang, China17:20 S9.2c Exploring the pathogenic roles of Fonsecaea cell wall melanin

through case to bench study Jiufeng Sun, China17:45 S9.2d Coccidioidomycosis: Imported and possible domestic cases in

China, a review from 1958 to 2017 Guanzhao Liang, China

S9.3 Dosing antifungal from the XXS to XXXL Forum Convener: Roger Brüggeman, the Netherlands

16:30 S9.3a Impact of critical illness on antifungal drug pharmacokinetics - need for individualisation of therapy?

Roger Brüggeman, the Netherlands 16:55 S9.3b From mother to child and their ontogeny with a focus on

antifungal drugs Catherine Sherwin, USA17:20 S9.3c The heavy weight championship – impact of obesity on

pharmacokinetics and dynamics Catherijne Knibbe, the Netherlands17:45 S9.3d Serum isavucoanzole (ISA) troughs in adult solid organ transplant

patients (SOT pts) receiving prophylaxis Hong Nguyen, USA

16:40 S8.6e Taxonomy of Mucor Lysett Wagner, Germany 17:05 S8.6f Challenges in clinical management of mucormycosis in children Zoi Pana, Greece17:30 S8.6g Rare invasive yeast infections Luisa Durán Graeff, Chile17:55 Discussion

S8.7 New developments in dermatomycosisE108 Convener: Pietro Nenoff, Germany

15:00 S8.7a Inflammation of the gut alters the microbial balance and leads to Candida glabrata cell wall remodeling

Samir Jawhara, France15:10 S8.7b Antifungal drug resistance of Trichophyton clinical isolates Michel Monod, Austria15:20 S8.7c Trichophyton mentagrophytes genotype Thailand Type 1 as

causative pathogen of abscessing dermatophytoses - tinea genitalis and barbae - in Germany(2012–2017) in Greece

Pietro Nenoff, Germany15:30 S8.7d Survey on dermatophyte infections over the past 6 years

(2012–2017) in Greece Michael Arabatzis, Greece15:40 S8.7e Validation of the DermaGenius® 2.0; a multiplex real-time PCR for

the identification of dermatophytes species in nail, hair and skin Giel Gaajetaan, the Netherlands15:50 S8.7f An alarming epidemic of clinically striking and frequently

relapsing steroid-modified dermatophytoses in India – a public health concern

Pietro Nenoff, Germany16:00 S8.7g Hair fungal Infection - precise diagnosis and therapeutic effect

evaluation by dermoscopy and fluorescent staining Yuping Ran, China16:10 S8.7h Discussion

16:30 – 18:00 Parallel session IX

S9.1 Genotyping in the NGS eraE103 Convener: Stephane Bretagne, France & Colin Brown, USA

16:30 S9.1a Tracing the evolution of virulence in Cryptococcus neoformans using population sequencing

Christina Cuomo, USA

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16:50 S9.7c Titan cell production reshapes Cryptococcus neoformans cell surface composition in order to modulate and/or evade the host immune system

Liliane Mukaremera, USA17:00 S9.7d Macrophage immune modulation by Secreted Molecules from Cryptococcus neoformans during infection Pedro Henrique Bürgel, United Kingdom 17:10 S9.7e The impact of extracellular vesicles on Cryptococcus neoformans

transmigration across brain endothelial cells Vanessa Silva, United Kingdom17:20 S9.7f Pathogenesis of clinical and environmental isolates of

Cryptococcus neoformans and Cryptococcus gattii in human brain microvascular endothelial cells: A comparative

Shayanki Lahiri Mukhopadhyay, India17:30 S9.7g Mismatch repair of DNA replication errors contributes to

microevolution and the emergence of resistance to antifungal drugs in Cryptococcus neoformans

Kylie Boyce, Australia 17:40 S9.7h Non-lytic exocytosis of Brazilian Cryptococcus neoformans clinical

isolates from macrophages André Nicola, Brazil17:50 Discussion

18:15 Departure canal cruises to congress dinnerStrandZuid Please see page 64 for more information

19:30 Congress dinner KIT Royal Please see page 64 for more information Tropical Institute

S9.4 MALDI-TOF in filamentous fungiE102 Convener: Maurizio Sanguinetti, Italy

16:30 S9.4a MALDI-TOF for molds, identification and beyond Maurizio Sanguinetti, Italy16:55 S9.4b Filamentous fungi MALDI-TOF identification in the clinical

laboratory Stephane Ranque, France17:20 S9.4c Maldi-Tof MS for the identification of filamentous fungi; a success

story outside the boundaries of the clinical lab? Marijke Hendrickx, Belgium17:45 S9.4d MALDI -TOF MS based identification of clinically important moulds

is faster and reliable- an experience from India Anup Ghosh, India

S9.5 Recent advances in diagnosing aspergillosisE104 Convener: Koichi Izumikawa, Japan

16:30 S9.5a How to standardize Aspergillus PCR protocols for testing various specimens

Lewis White, United Kingdom16:55 S9.5b Aspergillus identification by volatile organic compounds release Simona Cristescu, the Netherlands17:20 S9.5c Detection of invasive pulmonary aspergillosis in mice using lung

perfusion single photon emission computed tomography with 99mTc-MAA

Masato Tashiro, Japan 17:45 S9.5d AsperGenius versus MycoGENIE: Comparison of two commercial

Realtime PCR assays for detecting Aspergillus fumigatus in respiratory specimens

Dirk Schmidt, Germany

S9.7 Cryptococcus-host interactionsE108 Chair: Robin May, United Kingdom

16:30 S9.7a The Hormonal Milieu and its Effects on Virulence of Cryptococcus neoformans Tiffany Guess, USA16:40 S9.7b The effect of nutrient and temperature stress on the urease of the

opportunistic pathogen Cryptococcus neoformans Barbra Lerm, South Africa

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Wednesday 4 july, 2018

09:00 – 10:00 PS6 Translational mycology / From laboratory discovery to Forum patient care Chair: Sybren de Hoog, the Netherlands Axel Brakhage, Germany

10:00 – 10:30 Coffee break Forum & Ruby Lounge

10:30 – 12:00 Parallel session X

S10.1 The technical revolutions ahead of us NGS, proteomics,E103 Crispr-cas Convener: Sean Zhang, USA

10:30 S10.1a Genomic epidemiology of Candida auris within the United Kingdom, and the future of whole genome sequencing typing

Johanna Rhodes, United Kingdom10:55 S10.1b Applications of mass spectrometry for rapid and accurate

identification of molds and yeasts Joanna Freeke, Finland11:20 S10.1c Disruption of cotH genes of Mucor circinelloides via a plasmid-

free CRISPR/Cas9 system Csilla Szebenyi, Hungry 11:45 S10d Using CRISPR/Cas9 to unravel the complex role of single

nucleotide substitutions in Aspergillus fumigatus in-host adaptation

Eloise Ballard, United Kingdom

S10.2 ISHAM Working Group: Fungal PCR InitiativeE106 Convener: Peter Donnelly, the Netherlands

10:30 S10.2a The FPCRI past, present and future Rosemary Barnes, United Kingdom10:55 S10.2b Laboratory aspects Lewis White, United Kingdom11:20 S10.2c Clinical and translational aspects Mario Cruciani, Italy11:45 Discussion

WEDNESDAY 4 JULY, 2018

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11:10 S10.5c Isothermal amplification techniques, a tool for molecular diagnosis of eumycetoma

Sara Ahmed, Sudan11:25 S10.5d Development of Madurella mycetomatis Short Tandem Repeat

(MmySTR) assay for studying the genetic variance between different isolates

Bertrand Nyuykonge, the Netherlands11:40 Panel discussion – Closing the gap Discussion leader: Ahmed Hassan Fahal

S10.6 Fungal respiratory infections in Cystic FibrosisE107 Convener: Jean-Philippe Bouchara, France

10:30 S10.6a Treatment of airway colonization/respiratory infections with fungal pathogens

Carsten Schwarz, Germany10:55 S10.6b Developing omics approaches to elucidate pathogenic

mechanisms in Scedosporium species Nicolas Papon, France11:20 S10.6c Adaptation strategies of Aspergillus fumigatus in cystic fibrosis

patients Tobias Engel, the Netherlands11:45 S10.6d Serum (1?3)-ß-D-glucan and galactomannan levels in patients

with Cystic Fibrosis: a retrospective cohort study Jürgen Held, Germany

S10.7 Candida aurisE108

10:30 S10.7a Candida auris: report of the first case of infection from Australia Christopher Heath, Australia 10:40 S10.7b Internal validation of GPS™ CanAur dtec-qPCR Test following the

UNE/EN ISO/IEC 17025:2005 for detection of emergent nosocomial Candida auris

Antonio Martínez-Murcia, Spain10:50 S10.7c Genetic diversity, phenotypic variability and drug resistance in the

emerging fungal pathogen Candida auris Alexandre Lorenz, United Kingdom11:00 S10.7d Applicability of MALDI-TOF MS for rapid detection of resistant C.

auris strains to caspofungin Mansour Vatanshenassan, Germany

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S10.3 ISHAM-EFISG symposium: From non-responder to fungalForum breakthrough infections by opportunistic yeasts and molds Conveners: Sevtap Arikan-Akdagli, Turkey & Cornelia Lass-Flörl,

Austria

10:30 S10.3a How to define “non responder” and “fungal breakthrough” in yeasts and molds

Andreas Groll, Germany 10:55 S10.3b Current epidemiological trends: from prevalence to risk factors Ana Alastruey-Izquierdo, Spain11:20 S10.3c How to manage treatment failures Olivier Lortholary, France11:45 S10.3d Breakthrough fungal infections in solid organ transplant (SOT)

recipients receiving prophylaxis with isavuconazole and other antifungal agents

Cornelius Clancy, USA

S10.4 Ecology and outbreaksE102 Convener: Shawn Lockhart, USA

10:30 S10.4a Exploring the origin of outbreaks of mucormycosis Karlyn Beer, USA10:55 S10.4b Phylogenetic genome-level trees, population genetics and

species delineation in dimorphic fungi: Does it help us understand infection?

Marcus Teixeira, Brazil11:30 S10.4c Candidiasis: What are we missing by only looking in the blood? Hong Nguyen, USA11:45 S10.4d Epidemiological investigation for grouped cases of Trichosporon|

asahii using whole genome sequencing Marie Desnos-Ollivier, France

S10.5 Closing the mycetoma knowledge gapE104 Conveners: Wendy van de Sande, the Netherlands &

Ahmed Hassan Fahal, Sudan

10:30 Introduction Ahmed Hassan Fahal, Sudan10:40 S10.5a A holistic approach to the mycetoma management Sahar Bakhiet, Sudan10:55 S10.5b The treatment landscape of Mycetoma Ed Zijlstra, Switzerland

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11:10 S10.7e Azole and echinocandin antifungal drug resistance determinants of Candida auris

Milena Kordalewska, USA11:20 S10.7f Comparison of Candida auris candidemia with non-C. auris

candidemia: risk factors and outcome experience from Pakistan Syed Faisal Mahmood, Pakistan11:30 S10.7g Case-case comparison of Candida auris vs. other Candida

species bloodstream infections in Colombia Diego Cáceres, USA11:40 S10.7h Candida auris in Germany – report of the first clinical cases of an

emerging nosocomial pathogen Axel Hamprecht, Germany11:50 S10.7i Discussion

12:00 – 12:30 Closing Ceremony

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E-POSTER & POSTER PITCH PRESENTATIONS

PP1.007 Identification and characterization of novel Aspergillus fumigatus mycoviruses

Jan Zoll, the Netherlands PP1.008 Molecular epidemiology and antifungal susceptibility of Aspergillus

species isolated from asthma patients Mohammad Hedayati, Iran

Poster Terminal 2 Chair: Bart-Jan Kullberg, the Netherlands

PP1.041 Allergic bronchopulmonary aspergillosis presenting with lung mass-Report of six cases

Muhammad Irfan, Pakistan PP1.042 Galactomannan antigen as a diagnostic and prognostic marker in ICU

subpopulation suspected of Invasive Aspergillosis Yubhisha Dabas, India PP1.043 Invasive Aspergillosis: Performance of New and Established Diagnostic

Approaches with Same-Day Blood and Bronchoalveolar Lavage -- a Prospective Cohort Study

Sven Heldt, Austria PP1.044 Clinical features and outcome of Chronic Pulmonary Aspergillosis:

experience from a high tuberculosis burden country Nousheen Iqbal, Pakistan PP1.045 In vivo analysis of A. fumigatus sulphur-related transcriptome during

infection using a NanoString nCounter Plattform Monica Sueiro-Olivares, United Kingdom PP1.047 Pleurotus sajor-caju can be used to synthesize silver nanoparticles with

anti-fungal activity against Candida albicans Doblin Sandai, MalaysiaPP1.048 The presence of Candida albicans promotes Proteus mirabilis damage to

enterocytes Ilse Jacobsen, Germany

Poster Terminal 4Chair: Donna MacCallum, United Kingdom

PP1.081 Therapeutic effects of an antibody-derived peptide and its alanine scanning derivatives in a Galleria mellonella model of systemic candidiasis

Elisa Borghi, Italy PP1.082 Understanding the role of biofilms in recurrent vulvovaginal candidiasis

(RVVC) and their impact on therapy Ryan Kean, United Kingdom

E-Posters & Poster Pitch SessionsPosters are submitted electronically and can be retrieved as electronic posters (e-posters) on poster terminals that will be available during the entire congress.

The Poster Pitch Sessions will be held at the poster terminals in the Ruby Lounge.Selected posters will be discussed during the Poster Pitch Sessions. These sessions will have a specific common thematic focus and therefore will give you the opportunity to meet colleagues from other countries working in the same field of interest. The sessions will be guided by experts in the field. After the session there will be opportunity for further discussion.

Sunday 1 July: 12:15 - 13:15 hrs.Sunday 1 July: 18:00 - 19:00 hrs.Monday 2 July: 12:15 - 13:15 hrs.Monday 2 July: 18:00 - 19:00 hrs.Tuesday 3 July: 12:15 - 13:15 hrs.

You can find the E-poster Helpdesk in the Ruby Lounge

SUNDAY 1 JULY 2018Poster Pitch session I 12:15 – 13:15 hrs.Ruby Lounge

Poster Terminal 1Chair: TBA

PP1.001 Azole-resistance in Aspergillus terreus and closely related species, an overseen problem?

Michaela Lackner, Austria PP1.002 Predominance of non-fumigatus Aspergillus species among patients

suspected to pulmonary aspergillosis in a tropical and subtropical region Hossein Zarrinfar, Iran PP1.003 Aspergillosis of the paranasal sinuses Report of 7 cases treated by

Endoscopic Sinus Surgery (ESS) Batool Sadeghi-Nejad, IranPP1.004 Preliminary evaluation of a new immunochromatographic test for anti

Aspergillus antibodies detection Raphael Piarroux, FrancePP1.006 Molecular epidemiology and antifungal susceptibility profiles of

Aspergillus terreus complex Afsane Vaezi, Iran

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Poster Terminal 6Chair: Marcus Teixeira, USA

PP1.161 A singular case of eumycetoma of right leg due to exophiala jeanselmi Henry Harak, Italy PP1.162 Paracoccidioides antiadhesive peptide shows potential as a broad-

spectrum agent against different fungi Haroldo Cesar De Oliveira, Brazil PP1.163 Phenotyfipication and genotypification of Colombian clinical isolates of

Sporothrix spp from the medical mycology laboratory Universidad de Antiquia, Medellin, Colombia

Laura Carolina Alvarez Acevedo, Colombia PP1.164 Comparative study of lipid composition of the mycelial cell wall from

environmental and clinical isolates of Histoplasma capsulatum Araque Pedronel, Colombia PP1.165 Outbreak of zoonotic sporotrichosis in Southern Brazil Vanice Poester, Brazil PP1.166 Macrophage activation by IFN-? triggers restriction of phagosomal copper

from intracellular pathogens Qian Shen, USA PP1.167 Imaging mass spectrometry and microbial metabolomics on track of

infectious diseases Anton Skriba, Czech RepublicPP1.168 Unravelling the mechanistic basis of methionine synthase essentiality Jorge Amich, United Kingdom

Poster Terminal 8Chair: Cornelia Lass-Flörl, Austria

PP1.201 Prevalence of endobacterial symbiosis in Rhizopus microsporus (Tempe fungus)

Mohammad Javad Najafzadeh, Iran PP1.202 Development of the first commercial real-time PCR assay for the detection

of Mucorales species Giel Gaajetaan, the Netherlands PP1.203 The role of surface proteins in the virulence of Lichthemia corymbifera

with alveolar macrophages Mohamed Ismail Abdelwahab Hassan, Germany PP1.204 Mucormycete virulence and efficiency of posaconazole prophylaxis

depends on the underlying disease Günter Rambach, Austria

PP1.083 Major transcriptional modulations in S. aureus induced by the C. albicans secreted quorum sensing molecule farnesol

Vila Taissa, USA PP1.084 Distribution, Characterization and Antifungal susceptibility pattern of

Candida Species in various Clinical samples at a Multispecialty Hospital – Indian scenario

Swati Salila, India PP1.085 Protein kinase A governs growth and virulence in Candida tropicalis Chi-Jan Lin, Taiwan PP1.087 Comparative genomics of Aspergillus fumigatus and the role of

agricultural azoles on the emergence of resistance Amelia Barber, Germany PP1.088 In vitro antifungal susceptibility testing of Candida isolates from women

with recurrent vulvovaginal candidiasis Drosos Karageorgopoulos, Greece

Poster Terminal 5Chair: Pieter-Jan Haas, the Netherlands

PP1.121 Validation of diagnostic criteria for chronic pulmonary aspergillosis (CPA) Iain Page, United Kingdom PP1.122 Cutaneotrichosporon (Cryptococcus) cyanovorans, a basidiomycetous

yeast, described for the first time from the airways of cystic fibrosis patients Tjomme Van der Bruggen, the Netherlands PP1.123 Prevalence, identification and antifungal susceptibility pattern of Candida

species isolated from Iranian HIV patients with oropharyngeal candidiasis Maryam Roudbary, Iran PP1.124 The prevalence and diversity of fungi in respiratory samples of cystic

fibrosis patients – a Dutch, nationwide, prospective, multicentre study Tobias Engel, the Netherlands PP1.125 Identification of encapsulated viable Cryptococcus neoformans in

bronchoalveolar lavage of the patient with active pulmonary Tuberculosis and relapsing pneumonia

S. Amani Ghayoum, IranPP1.126 Meta-analysis of published molecular epidemiology data of the

Cryptococcus neoformans and C. gattii species complexes using the ISHAM MLST consensus

L. Trilles, Brazil PP1.127 Antifungal susceptibility of Cryptococcus neoformans/gattii spp complex;

Comparison between clinical and environmental isolates Nagarathna Siddaiah, India PP1.128 Interaction of Brazilian Clinical strains of Cryptococcus spp with macrophages Patricia Albuquerque, Brazil

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SUNDAY 1 JULY 2018Poster Pitch session II 18:00 - 18:15 hrs.Ruby Lounge

Poster Terminal 1 Chair: Bart-Jan Kullberg, the Netherlands

PP2.009 Study the effect of honey ingestion on recognition of Aspergillus fumigatus conidia by peritoneal macrophages

Donya Nikaein, Iran PP2.010 Occurrence of pathogenic Aspergillus species in drinking water from

restaurants in Kathmandu, Nepal Ushana Shrestha Khwakhali, Nepal PP2.011 Transcriptomic analysis of non –invasive infections by Aspergillus

fumigatus: the case of sino-nasal aspergillosis (SNA) in dogs Ivan Valdes, the NetherlandsPP2.012 In vitro combination of voriconazole with micafungin against azole-

resistant clinica isolates of Aspergillus fumigatus from different geographical regions

Hamed Fakhim, Iran PP2.013 Synergistic combinations of glabridin and voriconazole to battle against

Aspergillus fumigatus Mojtaba Nabili, Iran PP2.014 Molecular characterizations and in vitro susceptibility patterns of

Aspergillus fumigatus in a tertiary care hospital, 1999–2016 Weida Liu, China PP2.016 Volatile sulphur compounds produced by Pseudomonas aeruginosa

synergize with Aspergillus fumigatus in vivo enhancing the pathobiology of co-infection

Jorge Amich, United Kingdom

Poster Terminal 2 Chair: TBA

PP2.049 Involvement of iron metabolism in fluconazole susceptibility in Saccharomyces cerevisiae and Candida species

Liesbeth Demuyser, Belgium PP2.050 Cellular apoptosis: an alternative mechanism of action of caspofungin in

Candida glabrata Maryam Moazeni, Iran

PP1.205 Lichtheimia corymbifera: elucidating the mechanisms for iron acquisition and transport during infection

Felicia Adelina Stanford, Germany PP1.206 Multi-center study of Mucorales and other mould contamination of

freshly-laundered linens arriving at U.S. healthcare facilities Hong Nguyen, USA PP1.207 Heterogeneity and within-host adaption observed in clinical isolates of

Aspergillus fumigatus Ivan Valdes, the Netherlands PP1.208 Simple, low-cost micro-culture method for rapid diagnosis of

mucormycosis in murine model Hamid Badali, Iran

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PP2.096 Essential requirements for Candida albicans mediated damage of epithelial cells

Selene Mogavero, Germany

Poster Terminal 5Chair: Ferry Hagen, the Netherlands

PP2.129 Natural habitats of Cryptococcus neoformans and C gattii in the Caribbean Harish Gugnani, India PP2.130 Clinico-microbiological profile of Cryptococcal infections in non-HIV

infected patients Rungmei Marak, India PP2.131 The Effect of Novel Heterocyclic Compounds on Cryptococcal Biofilm Maya Korem, Israel PP2.132 Inflammasome modulation by Cryptococcus neoformans extracelular

vesicles produced in different conditions Clara Luna Freitas Marina, Brazil PP2.133 Antifungal activity of scorpions’ venom-derived antimicrobial peptides

against clinical isolates of Cryptococcus neoformans Fernanda Guilhelmelli Costa, Brazil PP2.134 Immunomodulatory effects of a scorpion-venom derived antimicrobial

peptide during the interaction of Cryptococcus neoformans with murine macrophages and dendritic cells

Calliandra De-Souza-Silva, Brazil PP2.135 Inducing pathogenicity of naive environmental C. neoformans var. grubii

isolates Hai Trieu Phan, Vietnam PP2.136 Phylogenetic analyses and B-cell epitope mapping of virulence factors of

C. neoformans and C. gattii: An in-silico insight Karuna Singh, India

Poster Terminal 6Chair: TBA

PP2.169 Cell wall robustness maintained under antibiotic stress by balanced synthesis of glucan and chitin

Jehan Abdel-moneim Abdelaziz, United Kingdom PP2.170 Fruits are Vehicles of Drug Resistant Pathogenic Yeasts Hsiu-Jung Lo, Taiwan PP2.171 Diagnosis of invasive fungal infections through detection of a circulating

pan fungal disaccharide by mass spectrometry. A european multicenter study Daniel Poulain, France

PP2.051 The Newly Characterization of a Candida albicans Isolate from a recurrent Cervica Lymphadenitis Patient and its Clinic Indication

Changzhen Zang, China PP2.052 Epitope unmasking in vulvovaginal candidiasis is associated with hyphal

growth and neutrophilic infiltration Eva Pericolini, Italy PP2.053 Candida glabrata epithelial cell damage Marina Pekmezovic, Germany PP2.054 Novel formulated nanocomposite containing Indolicidin and Graphene

Oxide against Candida albicans: in vitro and in vivo study Maryam Roudbary, Iran PP2.055 Transmission-frequency of Aspergillus fumigatus in cystic fibrosis patients

through coughing Tobias Engel, the Netherlands PP2.056 Experimental induction of tenuazonic acid toxicity in mice model Ankita Kumari, India

Poster Terminal 4Chair: Donna MacCallum, United Kingdom

PP2.089 Farnesol, tyrosol, and oxidative stress modulate the extracellular vesicle proteome and transcriptome in Candida albicans

Rosana Puccia, BrazilPP2.090 Inhibitory Effects of Lactobacillus Culture Supernatants on Candida

albicans Yuko Matsuda, JapanPP2.091 SCY-078: A first-in-class, orally-bioavailable, glucan synthase inhibitor has

broad spectrum activity against Candida, Aspergillus and Pneumocystis spp. Stephen Barat, USAPP2.092 Upregulation Gene Expression Levels of SAP 1-3 Vaginal Discharge

Candida albicans in Comparison to Culture of Candida albicans Isolates Seyedmahdi Hosseini, IranPP2.093 Virulence factors and susceptibility pattern of Candida albicans, Candida

tropicalis and Candida glabrata from clinical specimens, Mwanza-Tanzania Martha Mushi, TanzaniaPP2.094 Stress-contingent changes in Candida albicans SAPK pathway architecture

and regulation Alison Day, United KingdomPP2.095 Differential response of the bronchial epithelium and macrophages to

Aspergillus fumigatus allergens Sara Gago, United Kingdom

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MONDAY 2 JULY 2018Poster Pitch session III12:15 - 13:15 hrs.Ruby Lounge

Poster Terminal 1 Chair: Andreas Groll, Germany

PP3.017 ZnO nanoparticles coated by Chitosan-Linoleic acid inhibit the Candida growth and Biofilm formation in vitro

Maryam Roudbary, IranPP3.018 AtrR, an essential regulator of azole resistance in Aspergillus fumigatus,

acts via the TR34 element in the cyp51A promoter Scott Moye-Rowley, USA PP3.019 Aspergillus fumigatus strains are adapted to the lung environment in a

case of chronic pulmonary aspergillosis Sara Gago, United Kingdom PP3.020 Antifungal Activity and Cytotoxic Effect of Echinophora Extract, Carvacrol

and Drug Caspofungin on Vaginal Candida albicans Infections on Cervical Cancer

Mohammad Yadegari, Iran PP3.021 Environmentally acquired mutations in Aspergillus fumigatus leading to

azole resistance: An Asian situation Yubhisha Dabas, India PP3.022 Concomitant isolation of Aspergillus species and Mycobacterium species

in respiratory tract of patients: an underestimated microbial interaction? Sarah Dellière, France

PP3.023 Posaconazole tablet therapeutic drug monitoring in patients with chronic pulmonary aspergillosis

Chris Kosmidis, United Kingdom PP3.024 Aspergillus fumigatus fumagillin as possible virulence factor Xabier Guruceaga, Spain

Poster Terminal 2 Chair: TBA

PP3.057 Multiplex qPCR for rapid identification of Candida auris, C. haemulonii, C. duobushaemulonii and C. pseudohaemulonii

Amir Arastehfar, the NetherlandsPP3.058 Comparative virulence of Candida auris with Candida haemulonii,

Candida glabrata and Candida albicans in a murine model Hamed Fakhim, Iran

PP2.172 Omics approaches give new insights into genome variability and evolution of basal human pathogens of the order Mucorales

Volker Schwartze, Germany PP2.173 Extracellular vesicles in the black yeast Exophiala dermatitidis: a first

characterization Barbara Blasi, ViennaPP2.174 Transposable elements contribute to fungal genes and impact fungal

lifestyle Anna Muszewska, Poland PP2.175 Combining a whole blood infection assay with biomathematical modeling

to classify innate immune function Ines Leonhardt, Germany PP2.176 Determining the chemical composition and antifungal activities of

aromatic water of Trachyspermum ammi Kamiar Zomorodian, Iran

Poster Terminal 8Chair: Ana Alastruey-Izquierdo, Spain

PP2.209 Bioluminescent Mucor circinelloides – a promising new tool to study mucormycosis and antifungal drug efficacy

Ulrike Binder, Austria PP2.210 Molecular diagnosis of invasive aspergillosis in a child with clinical

suspicion of mucormycosis Raquel Sabino, Portugal PP2.211 Antifungal susceptibility patterns of rare yeasts Antonio Pérez Hansen, Austria PP2.212 Impact of the use of biomarkers on early discontinuation of emirical

antifungal therapy in critically ill patients: a randomised controlled study Anahita Rouzé, France PP2.213 Nanoantimicrobials: A critique on Susceptibility, Mechanism of action and

Toxicity on opportunistic fungal pathogens Umamaheswari K., IndiaPP2.214 Repurposing FDA-approved Ebselen and Auranofin as anti-fungal drugs:

teaching old drugs new tricks Ashok Chaturvedi, USA PP2.215 Impedance-based de-replication of antifungal drug classes Jurgen Wuyts, Belgium PP2.216 New Antifungal Lipopeptides from Wild- type Bacillus subtilis RLID 12.1 Ramya Ramachandran, India

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Poster Terminal 5 Chair: Vit Hubka, Czech Republic

PP3.137 In vitro inducing conditions to promote titan-like cells formation in C. neoformans Rocio García-Rodas, Spain PP3.138 Novel Dermatophytes from Indian soils Rahul Sharma, India PP3.139 In vitro and in vivo efficacy and toxicity of nonyl 3,4-dihydroxybenzoate, a

potent compound against dermatophytes biofilms Caroline Costa-Orlandi, Brazil PP3.140 New and emerging zoophilic dermatophytes in Europe Adela Cmoková, Czech RepublicPP3.141 Emergence of Trichophyton benhamiae in guinea pigs: a retrospective

study from the mycology laboratory of the veterinary college of Alfort Jacques Guillot, France PP3.142 Molecular epidemiology of Trichophyton mentagrophytes – a new

approach Silke Uhrlass, Germany PP3.143 A national survey on Tinea capitis in France: epidemiology and diagnostic

procedures Jean-Pierre Gangneux, France PP3.144 Place of Trichophyton soudanense in the Trichophyton rubrum complex: a

clinical isolates analysis Maud Gits-Muselli, France

Poster Terminal 6Chair: TBA

PP3.177 Conductivity: A novel approach for antifungal susceptibility testing Srivastava Neelabh, India PP3.178 Interactions with fungal cell wall polysaccharides determines the salt

tolerance of antifungal plant defensins Mark Bleackley, Australia PP3.179 The plant defensin HXP124 has the potential to be a new safe and

effective topical treatment for onychomycosis Nicole Van der Weerden, Australia PP3.180 The antifungal mechanism of action for plant defensins is defined via

treatment of a barcoded yeast deletion libraryf Kathy Parisi, Australia PP3.181 Fungal study of guano bat samples Cristine Goebel, Brazil

PP3.059 CoERG11 A395T mutation confers azole resistance in Candida orthopsilosis clinical isolates

Cosmeri Rizzato, Italy PP3.060 Severe recurrent vulvovaginal Candidiasis caused by mixed Candida

species Mohammad Effat, Egypt PP3.061 Optimization and application of fluorescent proteins in super-resolution

microscopy of Candida albicans Wouter Van Genechten, Belgium PP3.062 Ca37 monoclonal antibody inhibits Candida albicans growth in vitro and

in vivo Aitziber Antoran, Spain PP3.063 Activity of investigational tetrazole antifungals VT-1161 and VT-1598 against

a collection of clinical Candida tropicalis isolates with reduced fluconazole susceptibility

Jeffrey Rybak, USA

Poster Terminal 4 Chair: TBA

PP3.097 Development of echinocandin resistance after in vitro micafungin exposure in clinical isolates of Candida glabrata

Olga Rivero-Menendez, Spain PP3.098 Mechanisms of invisibility: 3D, real time and holographic imaging reveals

dynamics of Candida albicans evasion of host recognition June Bain, Spain PP3.099 Photodynamic inactivation can fight biofilms of Candida albicans strains

with constitutive efflux Helena Bujdáková, Slovak RepublicPP3.100 In vitro study of photodynamic inactivation against Fonsecaea monophora

and the application of ALA-APDT on refractory Chromoblastomycosis Liyan Xi, China PP3.101 Restoration Melanin of Fonseace monophora reduced Its Pathogenicity to

Galleria mellonella Yinghui Liu, China PP3.102 High-throughput RNA sequencing (RNA-seq) analysis of macrophages

infected with Fonsecaea monophora Junmin Zhang ChinaPP3.103 Fungal eye infections among ophthalmologic patients at ABSUTH, Aba,

Abia State, Nigeria Ada Ngwogu, Nigeria

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MONDAY 2 JULY 2018Poster Pitch session IV18:00 - 19:00 hrs.Ruby Lounge

Poster Terminal 1 Chair: TBA

PP4.025 Molecular identification and antifungal susceptibility testing of fungal agents isolated from patients with idiopathic pulmonary fibrosis(IPF) in Tehran, Iran

Maryam Roudbary, Iran PP4.026 Isolation of Aspergillus species in respiratory specimens from adult

patients with acute exacerbation of non-cystic fibrosis bronchiectasis; Data from Pakistan

Kauser Jabeen, Pakistan PP4.027 Azole resistance in Aspergillus fumigatus. Frequency and distributions of

mutations in a tertiary center in the Netherlands Jochem Buil, the Netherlands PP4.028 Development and multicentre evaluation of a screening method for

echinocandin susceptibility testing of Aspergillus spp. Joseph Meletiadis, Greece PP4.029 Molecular identification and antifungal susceptibility patterns of invasive

Aspergillus species following CLSI and EUCAST guidelines Yubhisha Dabas, India PP4.030 The IL17RA and CARD10 genes are important in controlling Aspergillus

fumigatus colonisation of the lung in allergic bronchopulmonary aspergillosis

Sara Gago, United Kingdom PP4.032 Overexpression of cyp51A and cyp51b contribute to triazole resistance in

clinical isolates of Aspergillus fumigatus from the United States Jeffrey Rybak, USA

Poster Terminal 2Chair: Maiken Arendrup, Denmark

PP4.065 Modulation of Candida albicans infection by the non-selective muscarinic receptor agonist pilocarpine hydrochloride

Christopher Nile, United Kingdom PP4.066 Do Candida albicans biofilms contain persister cells? Iryna Denega, France

PP3.183 Impaired phagocytosis directs human monocyte activation in response to fungal derived ß-glucan particles

Jessica Quintin, Brazil PP3.184 Cutaneous infection caused by Fusarium lichenicola in a patient with

verrucous hyperplasia vermiculatum manifestation Sha Lu, China

Poster Terminal 8 Chair: Michaela Lackner, Austria

PP3.217 Genome mining and transcriptomic analysis of iron metabolism genes in Scedosporium apiospermum

Yohann Le Govic, France PP3.218 Production of Scedosporium boydii CatA1 and SodC recombinant

proteins: another step towards a standardized test for serodiagnosis of Scedosporium infections

Sara Mina, Lebanon PP3.219 Hybrid histidine kinase III: new therapeutic target for Scedosporium

apiospermum? Anaïs Hérivaux, France PP3.220 Lignin degradation pathway in Scedosporium species Wilfried Poirier, France

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PP4.111 Molecular diagnostics of arthroconidial yeasts– frequent pulmonary opportunists

Engin Kaplan, Turkey PP4.112 Neglected diseases in Nigerians, diagnostics challenges: Invasive Fungal

Infections Rita Oladele, Nigeria

Poster Terminal 5Chair: Vishnu Chaturvedi, USA

PP4.145 Prevalence and virulence of the zoophilic dermatophyte Trichophyton benhamiae

Yvonne Gräser, Germany PP4.146 Epidemiology of dermatophytosis in the Caribbean Harish Gugnani, India PP4.148 Long-term practice of animal vaccination against dermatophytosis Marina Manoyan, Russia PP4.151 Application of real-time PCR assays for the diagnosis of histoplasmosis

using three molecular targets in human FFPE tissues and whole-blood Beatriz Lucia Gomez, Colombia PP4.152 Metagenomic analysis of environmental samples from mycetoma

endemic area in Sudan Sahar Bakhiet, Sudan

Poster Terminal 6 Chair: Anne van Diepingen, the Netherlands

PP4.185 Topical use of 1% luliconazole cream cured with Fusarium oxysporum infected refractory ulcers on an elderly patient’s leg and ankle

Xin Ran, China PP4.186 Primary cutaneous Fusarium solani infection in a hemodialysis patient Dongmei Shi, China PP4.187 Biological activity of lipids extracted from two isolates of Fusarium

oxysporum (environmental and clinical) in Galleria mellonella Pedronel Araque, ColombiaPP4.188 Diversity of clinically relevant Fusarium species complexes: preliminary

analysis of from an 11-yr prospective surveillance in France Dea Garcia-Hermoso, France PP4.189 Epidemiology and in vitro susceptibility of Fusarium species from human

infections in Germany – results of a retrospective multicenter study Axel Hamprecht, Germany PP4.190 Type 17 immunity controls Malassezia skin infection Florian Sparber, Switzerland

PP4.067 Identification of recessive lethal alleles in the Candida albicans genome: a constraint on loss-of-heterozygosity events in this species

Melanie Legrand, France PP4.068 Healthcare linen as a source of a mucormycosis case cluster that involved

different sites of infection and different Mucorales species Hong Nguyen, USA PP4.069 Genetically closely related azole-resistant Candida tropicalis in

environments can be a threat to healthcare Zi-Li Zhou, TaiwanPP4.070 Mapping the interaction of the Candida albicans multidrug resistance

ABC protein Cdr1 with pump inhibitor clorgyline that stimulates ATPase activity

Masakazu Niimi, Thailand PP4.071 Metabolic adaptation triggers Candida albicans biofilm phenotype Gordon Ramage, United Kingdom PP4.072 The use of long and short-read sequencing technology to elucidate

genomic variation and epidemiology of Candida glabrata in North America Rory Welsh, USA

Poster Terminal 4 Chair: Peter-Michael Rath, Germany

PP4.105 YEAST PANEL Multiplex PCR Assay for Identification of Invasive Yeast Pathogens: Novel Diagnostic Strategy, Useful for Developing Countries Amir Arastehfar, the Netherlands PP4.106 Increasing trend of mucormycosis mixed with other invasive mycoses from

a tertiary care centre in north India Jagdish Chander, India PP4.107 Invasive fungal diseases in patients with acute leukemia or allogeneic stem

cell transplantion recepients: A prospective multicenter observational study Gokhan Metan, Turkey PP4.108 A genetic and genomics approach identifies novel pathways of human

antifungal immune responses Vinod Kumar Magadi Gopalaiah, the Netherlands PP4.109 Epidemiology of fungaemia and fungal meningitis in Sweden: a nationwide

retrospective observational survey from sept 2015-aug 2016 Lena Klingspor, Sweden PP4.110 Comparative sequencing of ITS and D1/D2 domains of ribosomal DNA

for Molecular discrimination of fungal moulds Baskar Raju, India

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TUESDAY 3 JULY 2018Poster Pitch session V12:15 - 13:15 hrs.Ruby Lounge

Poster Terminal 1 Chair: Andreas Groll, Germany

PP1.005 Gene co-expression analysis identifies gene clusters associated with isotropic and polarized growth in Aspergillus fumigatus conidia

Tim Baltussen, the NetherlandsPP5.034 Composting as a resource for environmental azole resistance mutation in

Aspergillus fumigatus Bita Mousavi, France PP5.035 AfumID: An R Shiny application for Aspergillus fumigatus genotyping T.R. Sewell, United KingdomPP5.036 Environmental origin of clinical triazole resistance in Aspergillus fumigatus:

a longitudinal field study Sijmen Schoustra, the Netherlands PP5.037 Azole resistance of Aspergillus fumigatus in plant-decaying compost

model Jianhua Zhang, the NetherlandsPP5.038 Systematic interrogation of Aspergillus fumigatus cyp51A polymorphisms

for azole drug resistance Oliver Bader, GermanyPP5.039 Fungal contamination in horse stables and risk of equine aspergillosis:

results of a pilot study in France Jacques Guillot, FrancePP5.040 Chronic pulmonary aspergillosis in active pulmonary tuberculosis patients

in Jakarta, Indonesia Findra Setianingrum, United Kingdom

Poster Terminal 2 Chair: Maiken Arendrup, Denmark

PP5.073 The Kennedy pathway can increase the virulence of Candida albicans Todd Reynolds, USAPP5.074 Azole resistance and modulation of macrophage pro-inflammatory

response by Candida albicans MAM33 Neeraj Chauhan, USA PP5.075 Understanding the function of Pga15 family in Candida albicans

pathobiology Elham Khatrawi, United Kingdom

PP4.191 A rapid molecular assay for direct quantification of Malassezia pachydermatis in otic swabs

Gemma Castellá, Spain PP4.192 ‘PepBiotics’, novel antimicrobial peptides to fight fungal infections caused

by Aspergillus fumigatus and Malassezia furfur Hans De Cock, the Netherlands

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PP5.120 Molecular characterization, virulence determinants and antifungal susceptibility testing of Trichosporon asahii isolates from Nepal

Niranjan Nayak, Nepal

Poster Terminal 5 Chair: Marcus Teixeira, USA

PP5.153 New insights on fibrogenesis and serum biomarkers for pulmonary fibrosis in paracoccidioidomycosis

James Venturini, Brazil PP5.154 Human and veterinary blastomycosis caused by Blastomyces helicus and

B. percursus identified among global fungal collections Ilan Schwartz, CanadaPP5.155 Talaromyces marneffei cell wall glucans: their role in recognition by host

cell and pathogenicity Aakash Gupta, Australia PP5.156 Comparative genomics of Rhinocladiella mackenziei A. Ahmed, Saudi ArabiaPP5.157 Evaluation of Quantitative Real-Time PCR and Platelia Galactomannan

Assay for Diagnosis of Disseminated Talaromyces marneffei Infection Cunwei Cao, China PP5.158 Susceptibility to hydrogen peroxide and molecular characterization of

catalase encoding genes in different Sporothrix species Cinzia Barresi, Italy PP5.159 Tuberculosis and histoplasmosis diagnosis among people living with HIV/

AIDS: the impact of using rapid diagnostics tests in Panama, 2017 Diego Caceres, USA PP5.160 Veterinary mycosis in a tropical country Alejandra Calderón-Hernández, Costa Rica

Poster Terminal 6 Chair: Teun Boekhout, the Netherlands

PP5.193 Mating type and population genomics in Malassezia Qi-Ming Wang, China PP5.194 Morbidity of fungal infections caused by Malassezia furfur in neonatal

intensive care units Tatiana Priputnevich, Russia PP5.195 Molecular identification and speciation of Malassezia and its susceptibility

pattern Romald Packia Nancy, India

PP5.076 Studying the role of CgMIP1 in the evolution of Candida glabrata during adaption to the human host

Sofia Siscar-Lewin, Germany PP5.077 Addressing the Most Neglected Diseases through an Open Research

Model: the Discovery of Fenarimols as Novel Drug Candidates for Eumycetoma

Wilson Lim, the Netherlands PP5.078 Establishing burn wound models for infection with Candida spp Christin Von Mueller, Germany PP5.079 T2Candida and blood culture results predict mortality among patients with

candidemia Cornelius Clancy, USA PP5.080 A Simple and Noninvasive Zebrafish Egg Infection Model for Studying

Pathogenic Yeasts Hsiu-Jung Lo, Taiwan

Poster Terminal 4 Chair: Peter-Michael Raht, Germany

PP5.113 Predictive value of a nasopharyngeal aspirate sample for diagnosis of pulmonary Pneumocystis in infants: A prospective autopsy study

Sergio Vargas, Chile PP5.114 Comparative analysis of yeast species identification using phenotypic

methods and real-time PCR Tatiana Priputnevich, Russia PP5.115 Comparing small and high volume sample fungal with routine culture for

improved yield of mold from sputa Joveria Farooqi, Pakistan PP5.116 Molecular diagnostic strategies in cancer patients with suspected

respiratory mold infections Volker Rickerts, Germany PP5.117 Agreement between phenotypic and molecular method for the

identification of filamentous molds: Experience from a routine diagnostic laboratory from Pakistan

Seema Irfan, Pakistan PP5.118 Molecular epidemiology, risk factor analysis and Comparison of diagnostic

methods for Rapid Diagnosis of Fungal Pneumonia in Critically ill Cirrhotics Pratibha Kale, India PP5.119 Pneumocystis jirovecii pneumonia in patients with hematological diseases

after hematopoietic stem cell transplantation and chemotherapy Yuliya Rogacheva, Russia

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PP5.196 Activity of investigational tetrazole antifungals VT-1161 and VT-1598 against a collection of characterized fluconazole resistant Candida parapsilosis clinical isolates

Jeffrey Rybak, USAPP5.197 Polymerase chain reaction (PCR) diagnosis and identification of

mucormycosis in patients with suspected invasive fungal infection T. Shokohi, Iran PP5.198 Immunopathogenesis and virulence of invasive mucormycosis differs

considerably between mucormycete species Cornelia Speth, Austria PP5.199 Posaconazole prophylaxis in patients with acute myeloid leukemia: A real

life experience from a prospective multicenter observational study Gokhan Metan, Turkey PP5.200 Visceral mycoses in autopsied cases in Japan from 1989 to 2013:

increasing prevalence of cases with mucormycetes Yuhko Suzuki, Japan

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SOCIAL PROGRAM

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KIT Royal Tropical InstituteMauritskade 631092 AD Amsterdam

In 1926, after eleven years of building, the monumental building of KIT | Meetings & Events was completed. It is situated at Oosterpark and designed in neo-renaissance style by father and son Johannes Jacobus and Marie Adrianus van Nieukerken, upon instruction from the Colonial Institute that was founded in 1910 by private individuals and authorities. This is one of the first collaborations between

private individuals and the public sector. From here, research was conducted in the area of trade, anthropology and health care in the former Dutch colonies.The entire building was richly decorates with symbolic elements that refer to the various cultures of the world and the colonial history of the Netherlands. More than ten artists worked endlessly on sculptures, woodcarving and wrought iron to portray the trade, industry, foreign affairs, founders of the institute and the work done by it. The Marble Hall is the centre piece; the reception hall with its amazing twelve types of marble

SOCIAL PROGRAM

WELCOME RECEPTIONSaturday 30 June, 17:30 hrs.Welcome reception is offered to all registered delegates.The reception will take place on the exhibition and is free of charge.

YOUNG ISHAM EVENING Monday 2 July, 19:00 hrs. Following the scientific program on Monday 2 July, 19:00hrs. the Young ISHAM evening will be held at StrandZuid Amsterdam. This evening is only accessible for Young ISHAM members (and non-members) who are registered for this evening in advance. Not yet registered? Please check the registration desk for availability.Registered participants will receive an entry ticket for the evening in the delegate package.

Between RAI Amsterdam and the Beatrix Park (just a couple minutes walk from thecongress venue) you will find StrandZuid, a a chic inland beach complex. This evening will bring you an opportunity to network with colleagues while you enjoy a delicious barbecue and music.

StrandZuidEuropaplein 221078 GZ Amsterdam

CONGRESS DINNERTuesday 3 July, 18:00 hrs. The ISHAM Congress Dinner will be hosted in the KIT Royal Tropical Institute on Tuesday 3 July. All participants, who have pre-registered for the dinner, will receive an entry ticket in the delegate package. Not yet registered? Tickets are available at 95 EUR. Please check the registration desk for availability.

We gather at 18:00 hrs. at the main entrance of the RAI and will walk to the canal boats for a tour to the KIT Royal Tropical Institute. During the canal cruise we will explore the city while enjoying a snack and drinks.

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REGISTRATION Registration fee onsiteISHAM Members EUR 625 Day-registration EUR 300Non – members EUR 655 Convener / speakers EUR 295YISHAM members /Students* EUR 345 Emerging Economy Rate** EUR 250

* Students are asked to provide a proof of status (student card). ** Emerging Economy Rate is applied to individuals (no group registrations) from low-income

and lower-middle-income economies according to the HINARI list (Group A and Group B). Hinari Core Offer includes two groups of countries, areas, or territories (Group A and Group B). Both groups can register for this special rate.

The registration fee includes: Admission to the meeting, program and digital abstract book, certificate of attendance, welcome ceremony, welcome reception and the lunches and coffee breaks.

CancellationCancellations and refund requests must be submitted in writing to the congress secretariat. Cancellations made before 1 May 2018 will be refunded less 30% to cover administration costs. After this date no refunds will be given. All refunds will be made after the congress.

Opening hours registration desk Saturday 30 June 08:00 - 19:00 hrs. Tuesday 3 July 08:30 - 18:00 hrs.Sunday 1 July 08:30 - 18:00 hrs. Wednesday 4 July 08:30 - 12:00 hrs. Monday 2 Juy 08:30 - 18:00 hrs.

NamebadgeAccess to all scientific events and to the exhibits is only possible with you personal name badge, which you will receive upon registration. All participants are requested to wear their name badges during the entire congress.

Public transport: 5-day passRegistered delegates who orderd a transportation pass during their registration, will receive a transportation pass when they pick up their name badge. The five-day transportation ticket provides you with unlimited travel on all GVB trams, buses, and metros, both day and night. The ticket becomes valid the first time you check in.

Social events Please see below an overview of the social events:

Welcome reception Saturday 30 June 17:30 - 19:00 hrs.Young ISHAM evening Monday 2 July 19:00 - 01:00 hrs.Congress dinner Tuesday 3 July 18:00 - 22:30 hrs.

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GENERAL INFORMATION

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InsuranceIn registering for ISHAM 2018, delegates agree that neither the organisation nor the congress agency Congress Care is responsible for individual medical, travel or personal insurance. Delegates are requested to make their own travel and health insurance. The organizers cannot assume liability for changes.

ISHAM Congress Mobile App This App can be downloaded from the App store (Apple) or Google Play Store (Android) at no costs. You can download the app in four simple steps:

1. Go to the Appstore or Google Playstore and search for ‘Congress Care’2. Install and open the app on your phone or tablet.3. Select the event ISHAM 2018 and click on ‘install’4. The app is now ready for use

In this App you will find a detailed overview of the scientific programm, abstracts, posters, exhibition and floor plan. For assistance and questions regarding the App, please see the staff at the registration desk.

Opening hours ExhibitionSaturday 30 June 12:30 - 19:00 hrs.Sunday 1 July 09:30 - 18:00 hrs.Monday 2 July 09:30 - 18:00 hrs.Tuesday 3 July 09:00 - 18:00 hrs.Wednesday 4 July 09:30 - 12:30 hrs.

ISHAM TwitterISHAM can be followed on Twitter, via @ISHAM_Mycology. If you would like to share your tweets with other delegates following ISHAM Congress 2018, please use #ISHAM2018.

WIFIWireless internet is available for all congress delegates.Network: CONGRESSWIFIPassword: congress@rai

SecretariatCongress CarePo Box 440NL-5201 AK, ’s-HertogenboschThe NetherlandsTel. +31 (0)73 690 14 15www.congresscare.comisham2018@congresscare.cominfo@congresscare.com

GENERAL INFORMATION

AccreditationThe 20th Congress of the International Society for Human and Animal Mycology, Amsterdam, Netherlands, 30/06/2018-04/07/2018 has been accredited by the European Accreditation Council for Continuing Medical Education (EACCME®) with 20 European CME credits (ECMEC®s). Each medical specialist should claim only those hours of credit that he/she actually spent in the educational activity.

Through an agreement between the Union Européenne des Médecins Spécialistes and the American Medical Association, physicians may convert EACCME® credits to an equivalent number of AMA PRA Category 1 CreditsTM. Information on the process to convert EACCME® credit to AMA credit can be found at www.ama-assn.org/education/ earn-credit-participation-international-activities.

Live educational activities, occurring outside of Canada, recognised by the UEMS-EACCME® for ECMEC®s are deemed to be Accredited Group Learning Activities (Section 1) as defined by the Maintenance of Certification Program of the Royal College of Physicians and Surgeons of Canada.

Please find below the maximum points of ECMEC®s per day:

Sunday 1 July - 6 pointsMonday 2 July - 6 pointsTuesday 3 July - 6 pointsWednesday 4 July - 2 points

Certificate of attendanceCertificates of attendance will be sent afterwards by email.

Congress languageThe official language of the congress will be English.No simultaneous translation will be available.

Congress venueRAI AmsterdamEntrance EEuropaplein 241078 GZ Amsterdam

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EXHIBITORS SPONSORSSPONSORED SYMPOSIUM PFIZER

Date: Sunday 1 July, 2018Time: 12:30-13:30Location: Forum, RAI, the Netherlands

New opportunities for patient management in the fight against invasive mould disease (IMD)

12:30 Open and overview of IMD burden Prof. Peter Donnelly

12:40 Latest clinical data on management of invasive aspergillosis and mucormycosis Prof. Johan Maertens

13:00 Identifying suitable patients for new treatment strategies Prof. Oliver Cornely

13:20 Discussion and close All faculty

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The ISHAM 2018 congress has been supported by a grant from Gilead Sciences Europe Ltd

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FLOOR PLAN

Groundfloor

Firstfloor

MAIN ENTRANCEPARALLEL MEET INGROOMS

SPEAKERROOM

FORUM LOUNGE

PLENARY MEETING ROOM

FORUM

RUBY LOUNGE

E103

E104

E105

E106

E107

E108

E102Posters

RAI Congress Center, Amsterdam, The Netherlands

30 June - 4 July 2018

20th Congress of the International Society for Human and Animal Mycology (ISHAM)

www.isham2018.org

Program

www.isham2018.org

Regional scientific committeeAndreas GrollBart-Jan KullbergBas ZwaanEd KuijperFrank van de VeerdonkHan WöstenJohan MaertensJohan Mouton

Katrien LagrouMichael NeteaOliver CornelyPedro CrousPeter-Michael RathPieter Jan HaasTeun BoekhoutWendy van de Sande

Download the official ISHAM2018 APP

Do not forget to use #ISHAM2018 when posting photos and comments of the event on your social networks.

International scientific committeeAhmed Fahal Alexandro BonifazAna Alastruey-IzquierdoAndreas Groll, MunsterAndrew Ullman, WurzburgAnuradha ChowdharyArnaldo ColomboArturo CasadevallArunaloke Chakrabarti Ashraf IbrahimAxel BrakhageBernhard HubeBill SteinbachBirgit WillingerChristophe d’EnfertCornelia Lass-FloerlCornelius ClancyDarius Armstrong JonesDavid AndesDavid Denning David PerlinDimitrios KontoyiannisDonald SheppardDonna MacCallumElizabeth JohnsonEmanuel Roilides Eric DannaouiFlavio Queiros TellesGordon Brown

Hamid BadaliHan LiHideoki OgawaJean-Pierre Gangneux Jesus GuineaJoe HeitmanJoerg SteinmannJohan MaertensJosef Guarro, Josef MeletiadisKatrien LagrouLewis White, Livio PaganoLuis Ostrosky-Zeichner Mahmoud Ghannoum Maiken Arendrup Malcolm RichardsonManuel Cuenca, Marcus TeixeraMartin HoeniglMartin SchallerMatteo BasettiMatthew FisherMaurizio SanguinettiMichaela LacknerNathan Wiederhold Neil GowNelish GovenderNicolai Klimko

Nina Gunde-Cimerman Oliver CornelyOliver Kurzai Olivier LortholaryPatrice le PapePeter PappasPeter-Michael RathRetno WahyuningsihRoxana VitaleRuo-yu Li, Beijing, China Russel Edward Ruth AshbeeRyoji TsuboiSean Zhang,Sevtap Arikan Sharon Chen Shawn LockhartStephane BretagneStephane Ranque Thomas WalshTom Chiller, Tom PattersonTom RogersWanqing LiaoWei-da LiuWieland MeyerYee-Chun Chen

RAI Congress Center, Amsterdam, The Netherlands

30 June - 4 July 2018

20th Congress of the International Society for Human and Animal Mycology (ISHAM)

www.isham2018.org

Program

www.isham2018.org

Regional scientific committeeAndreas GrollBart-Jan KullbergBas ZwaanEd KuijperFrank van de VeerdonkHan WöstenJohan MaertensJohan Mouton

Katrien LagrouMichael NeteaOliver CornelyPedro CrousPeter-Michael RathPieter Jan HaasTeun BoekhoutWendy van de Sande

Download the official ISHAM2018 APP

Do not forget to use #ISHAM2018 when posting photos and comments of the event on your social networks.

International scientific committeeAhmed Fahal Alexandro BonifazAna Alastruey-IzquierdoAndreas Groll, MunsterAndrew Ullman, WurzburgAnuradha ChowdharyArnaldo ColomboArturo CasadevallArunaloke Chakrabarti Ashraf IbrahimAxel BrakhageBernhard HubeBill SteinbachBirgit WillingerChristophe d’EnfertCornelia Lass-FloerlCornelius ClancyDarius Armstrong JonesDavid AndesDavid Denning David PerlinDimitrios KontoyiannisDonald SheppardDonna MacCallumElizabeth JohnsonEmanuel Roilides Eric DannaouiFlavio Queiros TellesGordon Brown

Hamid BadaliHan LiHideoki OgawaJean-Pierre Gangneux Jesus GuineaJoe HeitmanJoerg SteinmannJohan MaertensJosef Guarro, Josef MeletiadisKatrien LagrouLewis White, Livio PaganoLuis Ostrosky-Zeichner Mahmoud Ghannoum Maiken Arendrup Malcolm RichardsonManuel Cuenca, Marcus TeixeraMartin HoeniglMartin SchallerMatteo BasettiMatthew FisherMaurizio SanguinettiMichaela LacknerNathan Wiederhold Neil GowNelish GovenderNicolai Klimko

Nina Gunde-Cimerman Oliver CornelyOliver Kurzai Olivier LortholaryPatrice le PapePeter PappasPeter-Michael RathRetno WahyuningsihRoxana VitaleRuo-yu Li, Beijing, China Russel Edward Ruth AshbeeRyoji TsuboiSean Zhang,Sevtap Arikan Sharon Chen Shawn LockhartStephane BretagneStephane Ranque Thomas WalshTom Chiller, Tom PattersonTom RogersWanqing LiaoWei-da LiuWieland MeyerYee-Chun Chen