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Cranial nerves
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Cranial nerves
1. Classification of the cranial nerves.
2. Characteristics of the cranial nerves.
3. Conductive pathways of the cranial nerves.
4. Involvement of cranial nerves in autonomic distribution.
5. Rules for cortical control on cranial nerves.
6. Connections of the cranial nerves.
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In accordance to direction of fibersSensory=ascending; motor=descending; mixed.
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Cranial nerves
N Cranial nerve Nuclei Outlet /inlet/ from the brain
Outlet /inlet/ from the skull
Sensory ganglions
Vegetative ganglia
Region of supply
I Olfactorius Olfactory
----------- ---------- it connects to the olfactory bulb
Enters the skull through the lamina cribrosa /cribriform plate/
------------ ----------- Mucous membrane of sup. nasal meatus
II Opticus Optic
----------- ------------it is continued by the optic tract
Enters through the canalis opticus /optic canal/
----------- ------------ Retina
III Oculomotorius Oculomotor
n.motoriusn.Iacubovichn.Perl/colliculi sup. of the midbrain/
Fossa interpeduncularis
Fissura orbitalis superior
----------- g.ciliare/in the orbit, near to the optic canal/
Mm. of eyeball: rectus med., sup., inf., oblique inf., M. levator palpebrae superiorSphincter pupillae & ciliary mm.
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N Cranial nerve Nuclei Outlet /inlet/ from the
brain
Outlet /inlet/ from the skull
Sensory ganglions
Vegetative ganglia
Region of supply
IV Trochlearis Trochlear
n.motorius/colliculi inf. of the midbrain/
Laterally from the pedunculi cerebri
Fissura orbitalis superior
------------- ------------ Sup. oblique m.
V Trigeminus Trigeminal n.ophthalmicusn.maxillarisn.mandibularis
n.motoriusn.pontinusn.mesencephalicusn.spinalis/rhomboid fossa/
Between the pons and middle cerebellar peduncles
Fissura orbitalis superiorFor.rotundumFor.ovale
g.trigeminale Gasser’s/near to the apex of the temporal pyramid/
------------ Face skin, mucous membrane of the nose, mouth, sinuses, teethMm. of mastication, mylohioid m.-ant.belli of digastric m., tensor velli palatini, tensor tympani
VI Abducens Abducent
n.motorius/rhomboid fossa/
Sul.bulbopontinus
Fissura orbitalis superior
----------- ----------- Lateral rectus m.
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VII Facialis Facial
n.motoriusn.solitarius /+IX+X/n.salivatorius superior/rhomboid fossa/
Sul.bulbopontinus
For.stylomastoideus
g.geniculi /inside of the pyramid of the temporal bone/
g,pterygopalatinum/fossa pterygopalatina/g.submandibulare /near the homonymous gland/
Ant. part of the tongueMm. of facial expression, post. belli of digastric m.,Lacrimal, submandibular, sublingual glands, mucous glands of face region
VIII Vestibulocochlearis Vestibulocochlear
2 nn.cochleares4 nn.vestibulares/rhomboid fossa/
Sul.bulbopontinus
Meatus acusticus internus
g.spirale Corti’s /in the cochlea, canalis spiralis/g.vestibulare/in the internal auditory meatus/
----------------- Semicircular canals, membranous vestibulum of the internal ear.
Cochlea
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IX Glossopharyngeus Glossopharyngeal
n.ambiguus /+X/n.solitarius /+VII+X/n.salivatorius inferior/rhomboid fossa/
Sul.retroolivarius
For.jugulare g.superius/in the jugular foramen/g.inferius /petrosum//in the petrosal fossa near to the jugular foramen/
g.oticum /exobase of the skull near to oval foramen/
Post.part body of the tongue, tonsils, pharynx, middle ear, sinocarotid glomulusStylopharyngeal m., pharyngeal mm.Parotid gland
X Vagus Vagus
n.ambiguus /+IX/n.solitarius /+VII+IX/n.dorsalis/rhomboid fossa/
Sul.retroolivarius
For.jugulare g.superius/in the jugular fossa/g.inferius/just below the jugular foramen/
gg.intraorganici or located near to organs
Post.part of the root of the tongue, epiglota, external earM.stylopharyngeus, pharyngeal mm.Pharynx, larynx, trachea, heart, lungs, GI tract
XI Accessorius Accessory
n.motorius/rhomboid fossa/
Sul.retroolivarius
For.jugulare ----------- --------------- Sternocleidomastoid, trapezius mm.
XII HypoglossusHypoglossal
n.motorius/rhomboid fossa/
Sul.preolivarius
Can.nervi hypoglossi
----------- --------------- Mm. of the tongue
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VIII
V, VII, IX, X
III, IV, VI, XI, XII
Classification of the cranial nervesIn according to their development all cranial nerves
are divided into 4 groups;●Derivatives of the brain (I,II);●Nerves developed in connection with the cranial miotoms
(III,IV,VI);●Derivatives of the visceral arches (V,VII,VIII,IX,X,XI);●Nerves developed through combining of the spinal nerves
(XII).
In according to their
components cranial
nerves can be classified
into:
2) sensory nerves
(I,II,VIII);
1) motor nerves
(IV,VI,XI.XII);
3) mixed nerves
(III,V,VII,IX,X)
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The cranial nerves exit the
brain in an orderly fashion.
Two, olfactory and optic, are
located in the telencephalon.
Two, occulomotor and
trochlear,
are located in the midbrain.
Four, trigeminal, abducens,
facial
and acoustovestibular, are
located
in the pons.
The remaining four,
glossopharyngeal,
vagus, accessory and
hypoglossal
are located in the medulla.
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It is most useful however to discuss them, not
related to location, but rather as to function.
There are 3 cranial nerves with primarily
sensory function.
Cranial nerve I, Olfactory, modulates smell,
cranial nerve II, Optic, modulates vision.
Cranial nerve VIII, Vestibulocochlear,
modulates hearing and balance.
There are 4 cranial nerves with primarily
motor function.
CN IV, Trochlear, innervates the superior oblique
muscle of the eyeball.
CN VI, Abducens, innervates the lateral rectus
muscle of the eyeball and abducts the eye.
CN XI, Accessory, innervates the trapezius
muscle in the back and shoulders.
CN XII, Hypoglossal, innervates the muscles of the
throat and enables us to swallow.
5 cranial nerves have mixed sensory, motor and
parasympathetic function.
The mixed cranial nerves are CN III Occulomotor,
CN V Trigeminal, CN VII Facial, CN IX
Glossopharyngeal and CN X Vagus.
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The occulomotor nerve of the six eyeball muscles.
It also carries Parasympathetic input to the ciliary
ganglion to constrict pupil.
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The trigeminal is a large important nerve which carries sensory input
from the face, cornea, mouth, nose and temporomandibular joint.
The trigeminal nerve also supplies motor innervation to the muscles of
mastication.
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The facial nerve carries taste
sensation from the anterior 2/3 tongue.
It also supplies Motor function to
the muscles of facial expression.
Finally it carries Parasympathetic input
to the salivary and lacrimal glands.
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The glossopharyngeal nerve
carries taste sensation from
the posterior 1/3 tongue.
It also carries general sensation
from the auditory tube and
pharynx.
It supplies stylopharyngeal
muscle.
It also supplies parasympathetic
input to the parotid gland.
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Last, but certainly not least, is the vagus.
It supplies general sensory and motor
function to the larynx and pharynx.
Perhaps most importantly it supplies
Parasympathetic input to the heart
and lungs and gastro intestinal
tract to the level of the splenic
flexure of the colon.
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Lamina cribrosa – I
Optic canal – II
Fissura orbitalis
superior –
III, IV, VI, V1
Foramen rotundum
– V2
Foramen ovale – V3
Meatus acusticus
internus – VII, VIII
Foramen jugulare –
IX, X, XI
Canalis hypoglossalis -
XII
Exit /entrance/ of the
cranial nerves
from the skull
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Involvement of the cranial nerves in nerve-
supply to the organs
The cranial nerves may be grouped as follows:
● Oculomotor, trochlear, abducent, and hypoglossal nerves (III, IV, VI, XII and XI) supply skeletal muscle of specific regions of the head (eyeballs in the case of III, IV, and VI; tongue in the case of XII). Nerve III also contains parasympathetic fibers to the smooth muscle of the sphincter pupillae and the ciliary muscle (general visceral efferent). The spinal part of nerve XI supplies the sternomastoid and trapezius.
● Trigeminal nerve (V) contains motor fibers to the muscles of mastication (special visceral efferent) and sensory fibers from various parts of the head, e.g., face, nasal cavity, tongue, and teeth (general somatic afferent).
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● Facial, glossopharyngeal and vagus nerves (VII, IX, X) contain several components:
● (a) Motor fibers to the muscles of facial expression (VII) and the muscles of the pharynx and larynx (IX and X) (special visceral efferent). Many of the fibers to the pharynx and larynx are derived from nerve XI (internal branch) and travel by way of nerve X (hence XI is "accessory" to the vagus).
● (b) Parasympathetic secretory fibers to the lacrimal and salivary glands (nervus intermedius of VII), the salivary glands (IX), and certain glands associated with the respiratory and digestive systems (X) (general visceral efferent). Nerve X also supplies most of the smooth muscle of the respiratory and digestive systems, as well as cardiac muscle.
● (c) Taste fibers (nervus intermedius of VII; also IX and X) (special visceral afferent).
● (d) Fibers from the mucous membrane of the tongue and pharynx (hence the name glossopharyngeal) and of much of the respiratory and digestive systems (general visceral afferent) are contained in nerves IX and X.
● Olfactory, optic, and vestibulocochlear nerves (I, II, and VIII) pertain to organs of special sense (special afferent).
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Ascending wayI. receiving part – in the region of sensory nerve-
supply
II. transmitter part:
ascending /sensory pathway/: has 3 neurons
the first - inside of sensory ganglion
the second - inside of the sensory nucleus
the third – in the thalamus
III. cortical center:
sensory: of general sensitivity – gyrus
postcentralis,
of taste & smell sensitivity – uncus
Descending somatic pathwayI. motor cortical center:
gyrus precentralis, gyrus paracentralis
II. descending somatic motor way:
has 2 neurons: the first - inside of cortex
(gyrus precentralis),
the second - inside of the motor nucleus
III. organ effector (striated muscles)
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Motor vegetative nerves have
descending way, which includes:
3 neurons:
1st - inside of superior vegetative
center.
2nd - inside of the vegetative nucle.
3rd - inside of vegetative ganglion
organ effector - smooth muscles,
glands.
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Connections of the cranial nerves - 2 groups of the connexions:
1) intrasystemic /with the cranial nerves/
2) intersystemic /with the spinal nerves/
Intrasystemic connexions at the level of the nuclei● fascial nerve has common sensory nucleus with the IX-th and X-th cranial
nerves
n. solitarius;
- the IX-th, X and XI-th have common motor nucleus – n. ambiguous;
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Intrasystemic connexions at the level of the branchesAll branches of the trigeminal nerve form connexions with other cranial nerves:- ophthalmic nerve forms conexion with the oculomotor nerve in the region of the ciliary ganglionmaxillary nerve connects with the facial nerve /parasympathetic fibers ofthe zygomatic nerve from the maxillary nerve and sensory fibers of the lacrimal nerve/mandibular nerve connects with: facial nerve in the region of the submandibular ganglion;glossopharyngeal nerve in the region of the otic ganglionaccessory nerve with the glossopharyngeal and vagus nerve;glossopharyngeal & vagus nerves form pharyngeal plexus.
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Intrasystemic
connections
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Intersystemic connections1) In the region of the head
Branches of the trigeminal have connexions
with the sympathetic fibers originated
from the superior cervical ganglion:
Ophthalmic nerve - with fibers of ophthalmic
plexus.
Mandibular nerve – with fibers of the facial
plexus and plexus of the middle cerebral artery.
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In the region of the neck
Facial nerve forms the cervical loop with the transverse nerve from the cervical plexus /formed by the spinal nerves.
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2) In the region of the neck
Hypoglossal nerve forms the cervical
loop with the motor branches
of the cervical spinal nerves.
4) In the region of the thorax
&abdomen
Nervus vagus forms multiple
connections
with branches of the sympathetic
trunk
/plexus cardiacus, esophageus,
bronchialis, celiac, upper & lower
mesenteric/.
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END