Download - Demography and deleterious alleles in maize
Demography and deleterious alleles in maize
Jeffrey Ross-Ibarra @jrossibarra • www.rilab.org
Dept. Plant Sciences • Center for Population Biology • Genome Center University of California Davis
photo by lady_lbrty
population genetics of deleterious alleles
Ne effective population size s selection coefficient
selection effective when 2Nes > 1
Lawrie and Petrov 2014
2Nes=0
2Nes=52Nes=100
population genetics of deleterious alleles
Ne effective population size s selection coefficient
selection effective when 2Nes > 1
genetic load: difference between fitness of optimal and averaged genotype
Lawrie and Petrov 2014
2Nes=0
2Nes=52Nes=100
population genetics of deleterious alleles
Ne effective population size s selection coefficient
selection effective when 2Nes > 1
increased load due to out-of-Africa bottleneckhe
tero
zygo
us p
er in
divi
dual
hom
ozyg
ous
deriv
ed p
er
indi
vidu
al
Lohmueller et al 2008
rela
tive
dive
rsity
(B)
distance (cM)
mutation distribution of
selective effects
distance from sitesum over all selected sites
⇡e
⇡0⇡ e
�P
x
R 10
u
x
f
x
(t)dt
t(1+(1�t)rx
/t)2
Nordborg 1996
Genome-wide diversity reduced by linked selection
purifying selection reduces diversity at linked sites
rela
tive
dive
rsity
(B)
distance (cM)
mutation distribution of
selective effects
distance from sitesum over all selected sites
⇡e
⇡0⇡ e
�P
x
R 10
u
x
f
x
(t)dt
t(1+(1�t)rx
/t)2
Nordborg 1996
How does demography affect the impact of selection on linked sites?
Genome-wide diversity reduced by linked selection
purifying selection reduces diversity at linked sites
how has the demography of domestication changed the impacts of selection against deleterious alleles?
Tim Beissinger USDA-ARS (U. Missouri) beissingerlab.org ANGSD: Korneliussen et al 2014
•3-5X sequencing depth •allele frequencies, diversity from genotype-likelihoods
genic nongenic genic nongenicpairw
ise n
ucle
otid
e di
vers
itymaize teosinte
diversity suggests selection and demography
Tim Beissinger USDA-ARS (U. Missouri) beissingerlab.org ANGSD: Korneliussen et al 2014
•3-5X sequencing depth •allele frequencies, diversity from genotype-likelihoods
genic nongenic genic nongenicpairw
ise n
ucle
otid
e di
vers
ity
Tajima’s D Tajima’s D
dens
itymaize teosinte
diversity suggests selection and demography
teos
inte
maize
DATA
teos
inte
maize
MODEL
domestication: bottleneck and expansion
dadi: Gutenkunst 2009
teos
inte
maize
DATA
teos
inte
maize
MODEL
domestication: bottleneck and expansion
dadi: Gutenkunst 2009
0.05Na
Na
Na 3Na
teosinte maize
0.05Na
Na
Na 3Nadadi diffusion:Ne ~ 450,000
SeeDs singletons:Ne ~ 1,000,000
model underestimates expansion
0.05Na
Na
Na 3Nadadi diffusion:Ne ~ 450,000
SeeDs singletons:Ne ~ 1,000,000
1e+05
1e+07
1e+09
1e+03 1e+042e+04 1e+05years(u=3e−8, generation=1)
effe
ctive
pop
ulat
ion
size
popBKN_4HapBKN_6HapTIL_4Hap_JaliscoTIL_6Hap
MSMC coalescent:Ne ~ 1,000,000,000
model underestimates expansion
0.05Na
Na
Na 3Nadadi diffusion:Ne ~ 450,000
SeeDs singletons:Ne ~ 1,000,000
1e+05
1e+07
1e+09
1e+03 1e+042e+04 1e+05years(u=3e−8, generation=1)
effe
ctive
pop
ulat
ion
size
popBKN_4HapBKN_6HapTIL_4Hap_JaliscoTIL_6Hap
MSMC coalescent:Ne ~ 1,000,000,000
49M hectares:Ne ~ 5,000,000,000
model underestimates expansion
simulations find effect for s (1/2Nteo)
bottleneck reduced neutral diversity
singletonspairwise diversity
simulations find effect for s (1/2Nteo)
singletons show reduced diversity
2Ns 10
singletonspairwise diversity
simulations find effect for s (1/2Nteo)
2Ns >>1 in both
singletonspairwise diversity
patterns of linked selection affected by both long-term and recent demographic change
Mexico lowland
9,000 BP
Matsuoka et al. 2002; Piperno 2006 Perry et al. 2006; Piperno et al. 2009
geographic spread post-domestication
Mexico highland6,000 BP
Mexico lowland
9,000 BP
Matsuoka et al. 2002; Piperno 2006 Perry et al. 2006; Piperno et al. 2009
geographic spread post-domestication
Mexico highland6,000 BP
S. America lowland
6,000 BP
Mexico lowland
9,000 BP
Matsuoka et al. 2002; Piperno 2006 Perry et al. 2006; Piperno et al. 2009
geographic spread post-domestication
Mexico highland6,000 BP
S. America lowland
6,000 BP
S. America Highland
4,000 BP
Mexico lowland
9,000 BP
Matsuoka et al. 2002; Piperno 2006 Perry et al. 2006; Piperno et al. 2009
geographic spread post-domestication
Mexico highland6,000 BP
S. America lowland
6,000 BP
S. America Highland
4,000 BP
Mexico lowland
9,000 BP
SeeD 1M SNPs
4K samples
●
●
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0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 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x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 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x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 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x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23y = 0.039 − 8.8e−07 ⋅ x, R = 0.23
0.00
0.02
0.04
0.06
0 2000 4000 6000 8000geographical distance to Balsas Valley (km)
perc
enta
ge o
f pol
ymor
phic
site
s
elevation100020003000
region●
●
●
Central AmericaMexicoSouth America
Sarah Hearne, CIMMYT
repeated colonization decreases Ne
distance from origin
hete
rozy
gosit
y
Mexico highland6,000 BP
S. America lowland
6,000 BP
S. America Highland
4,000 BP
Mexico lowland
9,000 BP
SeeD 1M SNPs
4K samples
repeated colonization decreases Ne
Takuno et al. 2015
Mexico Lowland
Mexico Highland
NA
NB
NC
N1 N2
N2P
tD tE
tF
NA
NB
NC
N1 N2
N2P
tD tE
tF
tmex
Nmex
NA
NB
NC
N1 N2
tD tE
tF
N3 N4
NC �ĮNA
N1 �ȕNC
N2 ����ȕ�NC
N2P� �ȖN2
NC �ĮNA
N1 �ȕNC
N2 ����ȕ�NC
N2P� �ȖN2
NC �ĮNA
N1 �ȕ1NC
N2 ����ȕ1�NC
N3 �ȕ2N2
N4 ����ȕ2�N2
N4P �ȖN4
tG
N4P Lowland Highland mexicana Mexico
Lowland SA
Lowland SA
Highland
Model IA Model IB Model II
Figure 2 Demographic models of maize low- and high-land populations. Parameters in bold were estimated inthis study. See text for details.
A HWE cut-off of P < 0.005 was used for each subpopu-lation due to our under-calling of heterozygotes. In total, weincluded 18,745 silent SNPs for the Mexican populations inModels IA and IB, 14,508 for the S. American populations inModel I and 11,305 for the Mexican lowland population andthe S. American populations in Model II. We obtained similarresults under more or less stringent thresholds for significance(P < 0.05 ⇠ 0.0005; data not shown), though the number ofSNPs was very small at P < 0.005. Demographic parameterswere inferred with the software �a�i (Gutenkunst et al. 2009),which uses a diffusion method to calculate an expected JFDand evaluates the likelihood of the data using a multinomialassumption.Model IA: This model is applied to the Mexican and S. Amer-ican populations. We assume the ancestral diploid popula-tion representing parviglumis follows a standard Wright-Fishermodel with constant size. The size of the ancestral popula-tion is denoted by NA. At tD generations ago, the bottleneckevent begins at domestication, and at tE generations ago, thebottleneck ends. The population size and duration of the bot-tleneck are denoted by NB and tB = tD � tE , respectively.The population size recovers to NC = ↵NA in the lowlands.Then, the highland population is differentiated from the low-land population at tF generations ago. The size of the low- andhighland populations at time tF is determined by a parameter� such that the population is divided by �NC and (1� �)NC .We assume that the population size in the lowlands is constantbut that the highland population experiences exponential ex-pansion after divergence: its current population size is � timeslarger than that at tF .isn’t this really a shrinking population in the lowlands, since �NC < NC ? wouldn’t
we want instead for lowlands to stay at NC and a new population branching off? how
much do we worry about this? actually, our conclusion holds when Iassumed the pop size of lowlands stays at NC . However, the
likelihood is a bit better in my original model.Model IB: We expand Model IA for the Mexican populationsby incorporating admixture from the teosinte mexicana to thehighland Mexican maize population. do we say ”Mexico population” or
”Mexican” (and thus ”South American”) ”population” throughout? as long as we’re
consistent probably OK either way. vote to Mexican population second
The time of differentiation between parviglumis and mexicanaoccurs at tmex generations ago. The mexicana population sizeis assumed to be constant at Nmex. At tF generations ago,the Mexican highland population is derived from admixturebetween the Mexican lowland population and a portion Pmex
from the teosinte mexicana .
Model II: The final model is for the Mexican lowland, S.American lowland and highland populations. This modelwas used for simulating SNPs with ascertainment bias (seebelow). At time tF , the Mexican and S. American lowlandpopulations are differentiated, and the sizes of populationsafter splitting are determined by �1. At time tG, S. Amer-ican lowland and highland populations are differentiated,and the sizes of populations at this time are determined by�2. As in Model IA, the S. American highland population isassumed to experience population growth with the parameter �.
Estimates of a number of our model parameters were avail-able from previous work. NA was set to 150,000 using esti-mates of the composite parameter 4NAµ ⇠ 0.018 from parvig-lumis (Eyre-Walker et al. 1998; Tenaillon et al. 2001, 2004;Wright et al. 2005; Ross-Ibarra et al. 2009) and an estimateof the mutation rate µ ⇠ 3 ⇥ 10
�8 (Clark et al. 2005) persite per generation. The severity of the domestication bottle-neck is represented by k = NB/tB (Eyre-Walker et al. 1998;Wright et al. 2005), and following Wright et al. (2005) we as-sumed k = 2.45 and tB = 1, 000 generations. Taking intoaccount archaeological evidence (Piperno et al. 2009), we as-sume tD = 9, 000 and tE = 8, 000. We further assumedtF = 6, 000 for Mexican populations in Models IA and IB(Piperno 2006), tF = 4, 000 for S. American populationsin Model lA (Perry et al. 2006; Grobman et al. 2012), andtmex = 60, 000, Nmex = 160, 000 (Ross-Ibarra et al. 2009),and Pmex = 0.2 (van Heerwaarden et al. 2011) for ModelIB. For both Models IA and IB, we inferred three parameters(↵, � and �), and, for Model II, we fixed tF = 6, 000 andtG = 4, 000 (Piperno 2006; Perry et al. 2006; Grobman et al.2012) and estimated the remaining four parameters (↵, �1, �2
and �).tF for model II is listed as 4,000 and 6,000 above. 6,000 is the number that matches
the lit best. is that what was used? if so, we should cite (Grobman et al. 2012) fixed
Differentiation between low- and highland popula-tions
We used our inferred demographic model to generate a nulldistribution of FST . As implemented in �a�i (Gutenkunst
4
Table 2 Inference of demographic parameters
Mexico Model I Model II
Likelihood �5592.80 Likelihood �4654.79
↵ 0.92 ↵ 1.5
� 0.38 � 0.76
� 1 � 1
South America Model I Model III
Likelihood �3855.28 Likelihood �8044.71
↵ 0.52 ↵ 1.0
� 0.97 �1 0.64
� 88 �2 0.95
� 54
Population structure
We performed a STRUCTURE analysis (Pritchard et al. 2000;Falush et al. 2003) of our landrace sample, varying the numberof groups from K = 2 to 6 (Figure 1, Figure S3). Most lan-draces were assigned to groups consistent with a priori popu-lation definitions, but admixture between highland and lowlandpopulations was evident at intermediate elevations (⇠ 1700m).Consistent with previously described scenarios for maize dif-fusion (Piperno 2006), we find evidence of shared ancestrybetween lowland Mexican maize and both Mexican highlandand S. American lowland populations. Pairwise FST amongpopulations reveals low overall differentiation (Table 1), andthe higher FST values observed in S. America are consistentwith decreased admixture seen in STRUCTURE. Archaeolog-ical evidence supports a more recent colonization of the high-lands in S. America (Piperno 2006; Perry et al. 2006; Grobmanet al. 2012), suggesting that the observed differentiation maybe the result of a stronger bottleneck during colonization of theS. American highlands.
Population differentiation under inferred demogra-phy
To provide a null expectation for allele frequency differentia-tion, we used the joint site frequency distribution (JFD) of low-land and highland populations to estimate parameters of twodemographic models using the maximum likelihood methodimplemented in �a�i (Gutenkunst et al. 2009). All models in-corporate a domestication bottleneck (Wright et al. 2005) andpopulation differentiation between lowland and highland popu-lations, but differ in their consideration of admixture and ascer-tainment bias (Figure 2; see Materials and Methods for details).
Estimated parameter values are listed in Table 2; while theobserved and expected JFDs were quite similar for both mod-els, residuals indicated an excess of rare variants in the ob-served JFDs in all cases (Figure 3). Under both models IA and
A
B
Lowlands
Hig
hlan
ds
Observation Expectation ResidualMexico
South America
40
–40
0
Model IA
Model IB
Density
Residual
10–4
0
10–310–210–1
Lowlands
Hig
hlan
ds
Observation Expectation Residual
40
–40
0
Model IA
Model II
Density
Residual
10–4
0
10–310–210–1
Figure 3 Observed and expected joint distributions of mi-nor allele frequencies in low- and highland populations in(A) Mexico and (B) S. America. Residuals are calculatedas (model � data)/
pmodel
IB, we found expansion in the highland population in Mexicoto be unlikely, but a strong bottleneck followed by populationexpansion is supported in S. American maize in both modelsIA and II. The likelihood value of model IB was higher thanthe likelihood of model IA by 850 units of log-likelihood (Ta-ble 2), consistent with analyses suggesting that introgressionfrom mexicana played a significant role during the spread ofmaize into the Mexican highlands (Hufford et al. 2013).
In addition to the parameters listed in Figure 2, we investi-gated the impact of varying the domestication bottleneck size(NB). Surprisingly, NB was estimated to be equal to NC , thepopulation size at the end of the bottleneck, and the likelihoodof NB < NC was much smaller than for alternative parame-terizations (Table 2, S2). This result appears to contradict ear-
7
Table 2 Inference of demographic parameters
Mexico Model I Model II
Likelihood �5592.80 Likelihood �4654.79
↵ 0.92 ↵ 1.5
� 0.38 � 0.76
� 1 � 1
South America Model I Model III
Likelihood �3855.28 Likelihood �8044.71
↵ 0.52 ↵ 1.0
� 0.97 �1 0.64
� 88 �2 0.95
� 54
Population structure
We performed a STRUCTURE analysis (Pritchard et al. 2000;Falush et al. 2003) of our landrace sample, varying the numberof groups from K = 2 to 6 (Figure 1, Figure S3). Most lan-draces were assigned to groups consistent with a priori popu-lation definitions, but admixture between highland and lowlandpopulations was evident at intermediate elevations (⇠ 1700m).Consistent with previously described scenarios for maize dif-fusion (Piperno 2006), we find evidence of shared ancestrybetween lowland Mexican maize and both Mexican highlandand S. American lowland populations. Pairwise FST amongpopulations reveals low overall differentiation (Table 1), andthe higher FST values observed in S. America are consistentwith decreased admixture seen in STRUCTURE. Archaeolog-ical evidence supports a more recent colonization of the high-lands in S. America (Piperno 2006; Perry et al. 2006; Grobmanet al. 2012), suggesting that the observed differentiation maybe the result of a stronger bottleneck during colonization of theS. American highlands.
Population differentiation under inferred demogra-phy
To provide a null expectation for allele frequency differentia-tion, we used the joint site frequency distribution (JFD) of low-land and highland populations to estimate parameters of twodemographic models using the maximum likelihood methodimplemented in �a�i (Gutenkunst et al. 2009). All models in-corporate a domestication bottleneck (Wright et al. 2005) andpopulation differentiation between lowland and highland popu-lations, but differ in their consideration of admixture and ascer-tainment bias (Figure 2; see Materials and Methods for details).
Estimated parameter values are listed in Table 2; while theobserved and expected JFDs were quite similar for both mod-els, residuals indicated an excess of rare variants in the ob-served JFDs in all cases (Figure 3). Under both models IA and
A
B
Lowlands
Hig
hlan
ds
Observation Expectation ResidualMexico
South America
40
–40
0
Model IA
Model IB
Density
Residual
10–4
0
10–310–210–1
LowlandsH
ighl
ands
Observation Expectation Residual
40
–40
0
Model IA
Model II
Density
Residual
10–4
0
10–310–210–1
Figure 3 Observed and expected joint distributions of mi-nor allele frequencies in low- and highland populations in(A) Mexico and (B) S. America. Residuals are calculatedas (model � data)/
pmodel
IB, we found expansion in the highland population in Mexicoto be unlikely, but a strong bottleneck followed by populationexpansion is supported in S. American maize in both modelsIA and II. The likelihood value of model IB was higher thanthe likelihood of model IA by 850 units of log-likelihood (Ta-ble 2), consistent with analyses suggesting that introgressionfrom mexicana played a significant role during the spread ofmaize into the Mexican highlands (Hufford et al. 2013).
In addition to the parameters listed in Figure 2, we investi-gated the impact of varying the domestication bottleneck size(NB). Surprisingly, NB was estimated to be equal to NC , thepopulation size at the end of the bottleneck, and the likelihoodof NB < NC was much smaller than for alternative parame-terizations (Table 2, S2). This result appears to contradict ear-
7
lowlands
high
land
s
landrace genomes to test colonization and genetic load●
●●●●●
●●
●
●
●●●
●●●●● ●
●
●●
●
●
●
●
●
●
●
●
●
−10
0
10
20
30
−110 −100 −90 −80 −70longitude
latit
ude
population●
●
●
●
●
●
AndesGua_HighlandMex_HighlandMex_LowlandSA_LowlandSW_US
distribution of samples
32 genomes, 20X coverage
Li Wang, Iowa State
phylogenetic conservation identifies deleterious alleles
GERP = neutral - observed substitution rate
Davydov et al., 2010; Rodgers-Melnick et al., 2015
phylogenetic conservation identifies deleterious alleles
GERP = neutral - observed substitution rate
Davydov et al., 2010; Rodgers-Melnick et al., 2015
GERP≤0 mutation neutral
phylogenetic conservation identifies deleterious alleles
GERP = neutral - observed substitution rate
Davydov et al., 2010; Rodgers-Melnick et al., 2015
GERP≤0 mutation neutral
GERP>0 mutation deleterious
GERP consistent with population genetic predictions of deleterious alleles
r = -0.8, P value < 0.01
Allele Frequency Recombination Quantiles
GER
P
GER
P
● ●
75000
100000
125000
150000
175000
Andes SA_Low MexHigh MexLow SW_US GuaHigh
sum
leng
th o
f RO
Hs(
kb)
popAndesGua_HighlandMex_HighlandMex_LowlandSA_LowlandSW_US
●
●
●
●
190000
210000
230000
Andes SA_Low MexHigh MexLow SW_US GuaHigh
load
popAndesGua_HighlandMex_HighlandMex_LowlandSA_LowlandSW_US
gene
tic lo
ad (
GER
P)
runs
of h
omoz
ygos
ityrecently bottlenecked Andean populations
show increased load
●
●
●
●
190000
210000
230000
Andes SA_Low MexHigh MexLow SW_US GuaHigh
load
popAndesGua_HighlandMex_HighlandMex_LowlandSA_LowlandSW_US
Piperno 2006; Perry et al. 2006; Piperno et al. 2009
domestication in Mexico lowland
9,000 BP
highland colonization led to mexicana sympatry
Piperno 2006; Perry et al. 2006; Piperno et al. 2009
Mexico highland6,000 BP
domestication in Mexico lowland
9,000 BP
PhotobyPesachLubinsky
mexicanamaize
highland colonization led to mexicana sympatry
introgressed teosinte haplotypes have lower load
Hufford et al. 2013
% in
trogr
esse
d
chromosome position (Mb)
introgressed teosinte haplotypes have lower load
Introgressed Not introgressed
% S
NPs
with
GER
P>0
Hufford et al. 2013
% in
trogr
esse
d
chromosome position (Mb)
heterosis drives change in fitness (yield) in maize
Springer and Stupar 2007 Crow 1998
P1 P2F1
Photo: Peter Yang
East 1936; Shull 1948
Dominant Model Overdominant Model
Crow 1948; Gowen 1952
Crow 1998 Charlesworth and Willis 2009
33
Krieger et al, 2010 Yao et al 2013
evidence inconsistent with simple dominance
photo: Jim Birchler
experimentally evaluate heterosis
3 years, 7 phenotypes + BPH
Better-Parental Heterosis (BPH)
12 inbred lines: 66 hybrids
Rita Mumm U Illinois
Jinliang Yang UC Davis
yangjl.com
Yield
HeightFlowering
Time
whole-genome resequencing: 13.8M SNPs 500K SNPs at sites with GERP > 0
phenotypes and sequence
GBLUP estimate additive and dominance effects of GERP SNPs
additive effect of jth SNP
0-1-2 coding of genotype
0-1-0 coding of genotype
dominance effect of jth SNP
BLUE value of the ith hybrid
GERP score correlates with effect size for fitness-related traits
0.01
0.02
0.03
0.0 0.5 1.0 1.5 2.0GERP Score
Addi
tive
Effe
ct3e−0
64e−0
65e−0
66e−0
6
0.0 0.5 1.0 1.5 2.0GERP Score
Addi
tive
Varia
nce
0.00
0.01
0.02
0.03
0.0 0.5 1.0 1.5 2.0GERP Score
Dom
inan
t Effe
ct0e
+00
5e−0
71e−0
6
0.0 0.5 1.0 1.5 2.0GERP Score
Dom
inan
t Var
ianc
e
0.0
0.1
0.2
0.3
0.4
0.0 0.5 1.0 1.5 2.0GERP Score
Deg
ree
of D
omia
nce
(k)
4.5e−0
65.
0e−0
65.
5e−0
66.
0e−0
6
0.0 0.5 1.0 1.5 2.0GERP Score
Tota
l Var
ianc
e
β!=0β=0
0.01
0.02
0.03
0.0 0.5 1.0 1.5 2.0GERP Score
Addi
tive
Effe
ct3e−0
64e−0
65e−0
66e−0
6
0.0 0.5 1.0 1.5 2.0GERP Score
Addi
tive
Varia
nce
0.00
0.01
0.02
0.03
0.0 0.5 1.0 1.5 2.0GERP Score
Dom
inan
t Effe
ct0e
+00
5e−0
71e−0
6
0.0 0.5 1.0 1.5 2.0GERP Score
Dom
inan
t Var
ianc
e
0.0
0.1
0.2
0.3
0.4
0.0 0.5 1.0 1.5 2.0GERP Score
Deg
ree
of D
omia
nce
(k)
4.5e−0
65.
0e−0
65.
5e−0
66.
0e−0
6
0.0 0.5 1.0 1.5 2.0GERP Score
Tota
l Var
ianc
e
0.01
0.02
0.03
0.0 0.5 1.0 1.5 2.0GERP Score
Addi
tive
Effe
ct3e−0
64e−0
65e−0
66e−0
6
0.0 0.5 1.0 1.5 2.0GERP Score
Addi
tive
Varia
nce
0.00
0.01
0.02
0.03
0.0 0.5 1.0 1.5 2.0GERP Score
Dom
inan
t Effe
ct0e
+00
5e−0
71e−0
6
0.0 0.5 1.0 1.5 2.0GERP Score
Dom
inan
t Var
ianc
e
0.0
0.1
0.2
0.3
0.4
0.0 0.5 1.0 1.5 2.0GERP Score
Deg
ree
of D
omia
nce
(k)
4.5e−0
65.
0e−0
65.
5e−0
66.
0e−0
6
0.0 0.5 1.0 1.5 2.0GERP Score
Tota
l Var
ianc
e
0.01
0.02
0.03
0.0 0.5 1.0 1.5 2.0GERP Score
Addi
tive
Effe
ct3e−0
64e−0
65e−0
66e−0
6
0.0 0.5 1.0 1.5 2.0GERP Score
Addi
tive
Varia
nce
0.00
0.01
0.02
0.03
0.0 0.5 1.0 1.5 2.0GERP Score
Dom
inan
t Effe
ct0e
+00
5e−0
71e−0
6
0.0 0.5 1.0 1.5 2.0GERP Score
Dom
inan
t Var
ianc
e
0.0
0.1
0.2
0.3
0.4
0.0 0.5 1.0 1.5 2.0GERP Score
Deg
ree
of D
omia
nce
(k)
4.5e−0
65.
0e−0
65.
5e−0
66.
0e−0
6
0.0 0.5 1.0 1.5 2.0GERP Score
Tota
l Var
ianc
e
Fl. Time
Height
Yield
GERP score GERP score
Add
itive
effe
ct
Dom
inan
t effe
ct
deleterious SNPs are more recessive for fitness
0.01
0.02
0.03
0.0 0.5 1.0 1.5 2.0GERP Score
Addi
tive
Effe
ct3e−0
64e−0
65e−0
66e−0
6
0.0 0.5 1.0 1.5 2.0GERP Score
Addi
tive
Varia
nce
0.00
0.01
0.02
0.03
0.0 0.5 1.0 1.5 2.0GERP Score
Dom
inan
t Effe
ct0e
+00
5e−0
71e−0
6
0.0 0.5 1.0 1.5 2.0GERP Score
Dom
inan
t Var
ianc
e
0.0
0.1
0.2
0.3
0.4
0.0 0.5 1.0 1.5 2.0GERP Score
Deg
ree
of D
omia
nce
(k)
4.5e−0
65.
0e−0
65.
5e−0
66.
0e−0
6
0.0 0.5 1.0 1.5 2.0GERP Score
Tota
l Var
ianc
eβ!=0β=0
0.01
0.02
0.03
0.0 0.5 1.0 1.5 2.0GERP Score
Addi
tive
Effe
ct3e−0
64e−0
65e−0
66e−0
6
0.0 0.5 1.0 1.5 2.0GERP Score
Addi
tive
Varia
nce
0.00
0.01
0.02
0.03
0.0 0.5 1.0 1.5 2.0GERP Score
Dom
inan
t Effe
ct0e
+00
5e−0
71e−0
6
0.0 0.5 1.0 1.5 2.0GERP Score
Dom
inan
t Var
ianc
e
0.0
0.1
0.2
0.3
0.4
0.0 0.5 1.0 1.5 2.0GERP Score
Deg
ree
of D
omia
nce
(k)
4.5e−0
65.
0e−0
65.
5e−0
66.
0e−0
6
0.0 0.5 1.0 1.5 2.0GERP Score
Tota
l Var
ianc
e
0.01
0.02
0.03
0.0 0.5 1.0 1.5 2.0GERP Score
Addi
tive
Effe
ct3e−0
64e−0
65e−0
66e−0
6
0.0 0.5 1.0 1.5 2.0GERP Score
Addi
tive
Varia
nce
0.00
0.01
0.02
0.03
0.0 0.5 1.0 1.5 2.0GERP Score
Dom
inan
t Effe
ct0e
+00
5e−0
71e−0
6
0.0 0.5 1.0 1.5 2.0GERP Score
Dom
inan
t Var
ianc
e
0.0
0.1
0.2
0.3
0.4
0.0 0.5 1.0 1.5 2.0GERP Score
Deg
ree
of D
omia
nce
(k)
4.5e−0
65.
0e−0
65.
5e−0
66.
0e−0
6
0.0 0.5 1.0 1.5 2.0GERP Score
Tota
l Var
ianc
e
0.01
0.02
0.03
0.0 0.5 1.0 1.5 2.0GERP Score
Addi
tive
Effe
ct3e−0
64e−0
65e−0
66e−0
6
0.0 0.5 1.0 1.5 2.0GERP Score
Addi
tive
Varia
nce
0.00
0.01
0.02
0.03
0.0 0.5 1.0 1.5 2.0GERP Score
Dom
inan
t Effe
ct0e
+00
5e−0
71e−0
6
0.0 0.5 1.0 1.5 2.0GERP Score
Dom
inan
t Var
ianc
e
0.0
0.1
0.2
0.3
0.4
0.0 0.5 1.0 1.5 2.0GERP Score
Deg
ree
of D
omia
nce
(k)
4.5e−0
65.
0e−0
65.
5e−0
66.
0e−0
6
0.0 0.5 1.0 1.5 2.0GERP Score
Tota
l Var
ianc
e
Fl. Time
Height
Yield
Dom
inan
ce (
k) o
f be
nefic
ial a
llele
GERP score
deleterious SNPs are more recessive for fitness
0.01
0.02
0.03
0.0 0.5 1.0 1.5 2.0GERP Score
Addi
tive
Effe
ct3e−0
64e−0
65e−0
66e−0
6
0.0 0.5 1.0 1.5 2.0GERP Score
Addi
tive
Varia
nce
0.00
0.01
0.02
0.03
0.0 0.5 1.0 1.5 2.0GERP Score
Dom
inan
t Effe
ct0e
+00
5e−0
71e−0
6
0.0 0.5 1.0 1.5 2.0GERP Score
Dom
inan
t Var
ianc
e
0.0
0.1
0.2
0.3
0.4
0.0 0.5 1.0 1.5 2.0GERP Score
Deg
ree
of D
omia
nce
(k)
4.5e−0
65.
0e−0
65.
5e−0
66.
0e−0
6
0.0 0.5 1.0 1.5 2.0GERP Score
Tota
l Var
ianc
eβ!=0β=0
0.01
0.02
0.03
0.0 0.5 1.0 1.5 2.0GERP Score
Addi
tive
Effe
ct3e−0
64e−0
65e−0
66e−0
6
0.0 0.5 1.0 1.5 2.0GERP Score
Addi
tive
Varia
nce
0.00
0.01
0.02
0.03
0.0 0.5 1.0 1.5 2.0GERP Score
Dom
inan
t Effe
ct0e
+00
5e−0
71e−0
6
0.0 0.5 1.0 1.5 2.0GERP Score
Dom
inan
t Var
ianc
e
0.0
0.1
0.2
0.3
0.4
0.0 0.5 1.0 1.5 2.0GERP Score
Deg
ree
of D
omia
nce
(k)
4.5e−0
65.
0e−0
65.
5e−0
66.
0e−0
6
0.0 0.5 1.0 1.5 2.0GERP Score
Tota
l Var
ianc
e
0.01
0.02
0.03
0.0 0.5 1.0 1.5 2.0GERP Score
Addi
tive
Effe
ct3e−0
64e−0
65e−0
66e−0
6
0.0 0.5 1.0 1.5 2.0GERP Score
Addi
tive
Varia
nce
0.00
0.01
0.02
0.03
0.0 0.5 1.0 1.5 2.0GERP Score
Dom
inan
t Effe
ct0e
+00
5e−0
71e−0
6
0.0 0.5 1.0 1.5 2.0GERP Score
Dom
inan
t Var
ianc
e
0.0
0.1
0.2
0.3
0.4
0.0 0.5 1.0 1.5 2.0GERP Score
Deg
ree
of D
omia
nce
(k)
4.5e−0
65.
0e−0
65.
5e−0
66.
0e−0
6
0.0 0.5 1.0 1.5 2.0GERP Score
Tota
l Var
ianc
e
0.01
0.02
0.03
0.0 0.5 1.0 1.5 2.0GERP Score
Addi
tive
Effe
ct3e−0
64e−0
65e−0
66e−0
6
0.0 0.5 1.0 1.5 2.0GERP Score
Addi
tive
Varia
nce
0.00
0.01
0.02
0.03
0.0 0.5 1.0 1.5 2.0GERP Score
Dom
inan
t Effe
ct0e
+00
5e−0
71e−0
6
0.0 0.5 1.0 1.5 2.0GERP Score
Dom
inan
t Var
ianc
e
0.0
0.1
0.2
0.3
0.4
0.0 0.5 1.0 1.5 2.0GERP Score
Deg
ree
of D
omia
nce
(k)
4.5e−0
65.
0e−0
65.
5e−0
66.
0e−0
6
0.0 0.5 1.0 1.5 2.0GERP Score
Tota
l Var
ianc
e
Fl. Time
Height
Yield
Dom
inan
ce (
k) o
f be
nefic
ial a
llele
GERP score
Phadnis and Fry 2005
but larger-effect loci do not contribute more to phenotypic variance0.
010.
020.
03
0.0 0.5 1.0 1.5 2.0GERP Score
Addi
tive
Effe
ct3e−0
64e−0
65e−0
66e−0
6
0.0 0.5 1.0 1.5 2.0GERP Score
Addi
tive
Varia
nce
0.00
0.01
0.02
0.03
0.0 0.5 1.0 1.5 2.0GERP Score
Dom
inan
t Effe
ct0e
+00
5e−0
71e−0
6
0.0 0.5 1.0 1.5 2.0GERP Score
Dom
inan
t Var
ianc
e
0.0
0.1
0.2
0.3
0.4
0.0 0.5 1.0 1.5 2.0GERP Score
Deg
ree
of D
omia
nce
(k)
4.5e−0
65.
0e−0
65.
5e−0
66.
0e−0
6
0.0 0.5 1.0 1.5 2.0GERP Score
Tota
l Var
ianc
e
β!=0β=0
0.01
0.02
0.03
0.0 0.5 1.0 1.5 2.0GERP Score
Addi
tive
Effe
ct3e−0
64e−0
65e−0
66e−0
6
0.0 0.5 1.0 1.5 2.0GERP Score
Addi
tive
Varia
nce
0.00
0.01
0.02
0.03
0.0 0.5 1.0 1.5 2.0GERP Score
Dom
inan
t Effe
ct0e
+00
5e−0
71e−0
6
0.0 0.5 1.0 1.5 2.0GERP Score
Dom
inan
t Var
ianc
e
0.0
0.1
0.2
0.3
0.4
0.0 0.5 1.0 1.5 2.0GERP Score
Deg
ree
of D
omia
nce
(k)
4.5e−0
65.
0e−0
65.
5e−0
66.
0e−0
6
0.0 0.5 1.0 1.5 2.0GERP Score
Tota
l Var
ianc
e
0.01
0.02
0.03
0.0 0.5 1.0 1.5 2.0GERP Score
Addi
tive
Effe
ct3e−0
64e−0
65e−0
66e−0
6
0.0 0.5 1.0 1.5 2.0GERP Score
Addi
tive
Varia
nce
0.00
0.01
0.02
0.03
0.0 0.5 1.0 1.5 2.0GERP Score
Dom
inan
t Effe
ct0e
+00
5e−0
71e−0
6
0.0 0.5 1.0 1.5 2.0GERP Score
Dom
inan
t Var
ianc
e
0.0
0.1
0.2
0.3
0.4
0.0 0.5 1.0 1.5 2.0GERP Score
Deg
ree
of D
omia
nce
(k)
4.5e−0
65.
0e−0
65.
5e−0
66.
0e−0
6
0.0 0.5 1.0 1.5 2.0GERP Score
Tota
l Var
ianc
e
0.01
0.02
0.03
0.0 0.5 1.0 1.5 2.0GERP Score
Addi
tive
Effe
ct3e−0
64e−0
65e−0
66e−0
6
0.0 0.5 1.0 1.5 2.0GERP Score
Addi
tive
Varia
nce
0.00
0.01
0.02
0.03
0.0 0.5 1.0 1.5 2.0GERP Score
Dom
inan
t Effe
ct0e
+00
5e−0
71e−0
6
0.0 0.5 1.0 1.5 2.0GERP Score
Dom
inan
t Var
ianc
e
0.0
0.1
0.2
0.3
0.4
0.0 0.5 1.0 1.5 2.0GERP Score
Deg
ree
of D
omia
nce
(k)
4.5e−0
65.
0e−0
65.
5e−0
66.
0e−0
6
0.0 0.5 1.0 1.5 2.0GERP Score
Tota
l Var
ianc
e
Fl. Time
Height
YieldD
omin
ance
Var
Tota
l Var
Add
itive
Var
GERP scoreGERP scoreGERP score
increasing heterosis
Height Yield
dominant
additive
recessive
Flow. Time
incomplete dominance important for fitness, heterosis
genomic prediction to test dominance models
BLUE value of the ith hybrid regression
coefficient for jth haplotype
block
weighted GERP scores under 3
models
Heterosis (BPH)Trait per se
Height Yield
Heterosis increasing
Flowering Time Height Yield
Heterosis increasing
Flowering Time
Incomplete Dominance
Complete Dominance
Additive
incomplete dominance explains more variance
5-fold cross-validation improves prediction by
*
** *
Height Yield
Heterosis increasing
Flowering Time
Heterosis (BPH)Trait per se
Height Yield
Heterosis increasing
Flowering Time
observed shuffled
concluding thoughts on deleterious alleles
• demographic change impacts purifying selection and effects on diversity at linked sites
• demographic impacts differ for alleles of different freqs
• deleterious alleles contribute substantially to phenotypic variation
• a simple incomplete dominance model can largely explain observed patterns of heterosis
Acknowledgments
Maize Diversity Group Peter Bradbury
Ed Buckler John Doebley Theresa Fulton
Sherry Flint-Garcia Jim Holland
Sharon Mitchell Qi Sun
Doreen Ware
Collaborators Matt Hufford (Iowa State)
Li Wang (Iowa State) Rita Mumm (U Illinois)
Ross-Ibarra Lab Tim Beissinger (USDA-ARS, MU)
Kate Crosby (Monsanto) Arun Durvasula (Vienna Biocenter)
Jinliang Yang (←hire this guy!) Sofiane Mezmouk (KWS)
sing
leto
n di
vers
ity
distance to nearest substitution (cM)
singletons still show now effect of hard sweeps
Title Text Title Text
1e+05
1e+07
1e+09
100 1000 10000years
effe
ctive
pop
ulat
ion
size
MSMC results support model
Sattah et al. 2011 PLoS Gen. Williamson et al. 2014 PLoS Gen Hernandez et al. 2011 Science
dive
rsity
Ne diploids
s selection coefficient
selection is effective if 2Nes > 1
Ne ~ 150,000 Ne ~ 10,000
Ne ~ 2,000,000 Ne ~ 600,000