50th Anniversary Landmark Study
OBJECTIVES
• Validate health benefits of Shaklee supplementation
• Compare Shaklee supplement users to other groups
• Confirm the safety of long term Shaklee supplement use
• First-of-its-Kind (Landmark) Study
• Collaboration with renowned nutritional epidemiologist
IMPORTANT HIGHLIGHTS
Dr. Gladys Block U.C. Berkeley
School of Public Health
• Proof of the Shaklee Difference
Another Multivitamin
Cross-sectional comparative analysis
of 3 populations
Shaklee Supplements
20+ Years
No Supplements
STUDY DESIGN
• Online Surveys sent to 1000+ qualified candidates
- Diet- Exercise- Health Status
• Measurements taken at 2005 Convention
- Anthropometric- Blood Samples
STUDY DESIGN
And now…..
The long awaited
STUDY RESULTS!
Shaklee Supplement
Users
Single Supplement
Users
NonSupplement
Users
Gender (Female/ Male) 58 / 42 45 / 55 40 / 60
Age 63 57 54BMI (kg/m2) 25.9 27.9 29.4Education> High School 86% 55% 29%
Annual Income> $70,000 62% 35% 33%
Comparison of Demographics
Shaklee Supplements Consumed on a Daily Basis by > 50%
of study participants:
Multivitamin/ mineral Calcium/ Vitamin D
B-complex Flavonoids
Vitamin C Lecithin
Carotenoids Garlic
Vitamin E Alfalfa
Omega-3 Fatty Acids
Soy Protein
Protein
CoQ10
Shaklee Supplement
Users
Other Multivitamin
Users
NonSupplement
Users
Iron-Female
(μg/L) 117.4 74.0 101.7
Iron-Male (μg/L) 117.6 205.2 198.2
Shaklee Supplement
Users
Other Multivitamin
Users
NonSupplement
Users
Vitamin C (mg/dL) 1.62 0.94 0.66Vitamin E (mg/dL) 2.9 1.4 1.1Iron-Female
(μg/L) 117.4 74.0 101.7
Iron-Male (μg/L) 117.6 205.2 198.2Vitamin A (μg/dL) 65.0 64.3 59.2
Vitamin D (nmol/L) 131.4 N/A N/A
Serum Nutrient Concentrations
ShakleeSupplement
Users
OtherMultivitamin
Users
NonSupplement
Users
9.69.1
6.1
Homocysteine
Key Biomarkers
HDL Cholesterol
ShakleeSupplement
Users
OtherMultivitamin
Users
NonSupplement
Users
50.953.3
57.5
55
Key Biomarkers
ShakleeSupplement
Users
OtherMultivitamin
Users
NonSupplement
Users
4.6
3.2
1.9
C-Reactive Protein
3.0
Key Biomarkers
ShakleeSupplement
Users
OtherMultivitamin
Users
NonSupplement
Users
180.1
145.3
121.0
Triglycerides
150
Key Biomarkers
ShakleeSupplement
Users
OtherMultivitamin
Users
NonSupplement
Users
7.4%
9.1%
2.5%
Heart Health
ShakleeSupplement
Users
OtherMultivitamin
Users
NonSupplement
Users
2.5%2.6%
1.8%
Vascular Health
ShakleeSupplement
Users
OtherMultivitamin
Users
NonSupplement
Users
Blood Sugar
2.9%
8.5%
11.1%
ShakleeSupplement
Users
OtherMultivitamin
Users
NonSupplement
Users
49%55%
84% Percentage that Rated Very Good to Excellent
Personal Health Assessment
Our Shaklee long-term multiple supplement users had:
IN SUMMARY
Increased Supplement
Intake
Increased Nutrition
Levels
Better Bio-Markers
Better Health
Status
FOUNDATION FOR A LONGER
& HEALTHIER LIFE
Vitalizer™
Dr. Forrest C. ShakleeCreated his first multivitamin in 1915
80 Bio-optimized nutrients clinically provento create a foundation for a longer, healthier life
Vitalizer™
The Vitalizer™ Concept
• UC Berkeley Study
• Comprehensive
• Universal Foundation
• Revolutionary Technology
Vitalizer™ in Numbers
50 Years VMS Experience
75 Shaklee Scientists
3 Years Intensive R&D
12 Shaklee Clinical Studies
80 Nutrients
4 Revolutionary Delivery Systems
12 Patents
= 1 Convenient Daily Dose
2 “Caroto-E-Omega”2 “Caroto-E-Omega”
2 Vita-Lea2 Vita-Lea Super Super Vitamin/Mineral ComplexVitamin/Mineral Complex
1 Sustained-Release B+C1 Sustained-Release B+C
1 Optiflora1 Optiflora Probiotic Probiotic
80 Bio-Optimized Nutrients
• Every Vitamin + Minerals your body needs
• Most powerful antioxidant spectrum
• Anti-aging nutrients
• 7 Omega-3 fatty acids
• Guaranteed super-active probiotics
Redefining VitalitySupercharged Vitality Antioxidant Defense
Heart HealthEye Health
Anti-Aging NutrientsDigestive Function
Stress ManagementBone Health
Joint Function Blood Sugar Support
Lung FunctionHealthy Skin, Hair & Nails
Nerve Function
Muscle Function
Brain Health Enhanced ImmunityDNA Protection
Prostate Health Healthy Teeth & GumsBreast Health
Vitality– Suboptimal Intake of
multiple nutrients:
• Vitamin A – 56%• Vitamin E – 69 %• Vitamin B6 – 54%• Calcium – 65%• Magnesium – 62%• Iron (women) – 62%• Zinc – 73%
USDA CSFII data, 1994-96
– GI Microflora, toxins80 Bio-Optimized Nutrients
Immune NutritionImmune Nutrition
– Vitamin A – 56 %Vitamin A – 56 %– Vitamin E – 69 %Vitamin E – 69 %– Vitamin BVitamin B66 – 54% – 54%– Folic Acid – 33%Folic Acid – 33%– Vitamin BVitamin B1212 – 17% – 17%– Zinc – 73% Zinc – 73% – CarotenoidsCarotenoids
USDA CSFII data, 1994-96USDA CSFII data, 1994-96
Omega-3 Fatty AcidsOmega-3 Fatty AcidsProbioticsProbiotics
Stress ManagementStress Management
Anti-Stress Nutrients: – B-Vitamins– Vitamin C– Magnesium
Shaklee
Micronutrient
Advanced
Release
Technology
SMART
SMART
The Right Nutrients
To the Right Place
At the Right Time!
***12 Patents, 2 Patents Pending***
1) Immediate Release
• Shaklee patented technology
• Folic acid micro-coating
• Releases within minutes in stomach
Vita-Lea® Super Vitamin/Mineral Complex
S MA R T
S MA R T
Immediate ReleaseVita-Lea® – Folic Acid
2) Sustained Release
• Tablet hydrates
• Gel layer forms
• Water soluble nutrients slowly diffuse through gel layer
• Patent pending
Gel-Diffusion Technology for B Vitamins & Vitamin C
S MA R T
S MA R T
Sustained 12+ Hour Release
Thiamine
0.0
20.0
40.0
60.0
80.0
100.0
120.0
140.0
160.0
0 1 2 3 4 5 6 7 8 9 10 11 12
Hours after Supplementation
Pla
sm
a t
ota
l th
iam
in (
nm
ol/
L)
C. Jensen & E. Norkus, UC Berkeley, CA and Our Lady of Mercy Medical Center, Bronx, NY;10 healthy volunteers; sponsored by Shaklee Corporation; submitted for publication
up to almost 200%
3) Delayed Release
• Prevents Omega-3 release in stomach– Creates excellent GI tolerance
• Rapid release in upper GI tract– Maximum bioavailability
• Expensive technology
• Pleasant vanilla aroma
pH-Activated Technology for “Caroto-E-Omega”
S MA R T
S MA R T
Delayed ReleasepH-Activated
4) Targeted Release
• L. acidophilus + B. longum
• Protected from stomach acid
• Release in lower GI tract
Patented Triple-Layer Encapsulation for Probiotics
332211
S MA R T
S MA R T
Targeted ReleaseOptiFlora® – Probiotic
4) Targeted Release
0.57 10
3.5
15
Powder Capsule Soft Gel Tablet OilCoating
Shaklee3x Layer
% Survival, Stomach
90
S MA R T
S MA R T
S.M.A.R.T.—really smart!
Vitalizer™ S.M.A.R.T. Delivery
• Space-saving technology– Using highly concentrated, pure ingredients– 6 versus 10-18!
• Convenience
Vitalizer™ for Everybody
Men 18-49 Women 18-49 Everybody 50+
Once Daily with a Meal
Vitalizer™
• Based on landmark supplement study– 8 of the top products from study are in Vitalizer
• Most complete formula & health benefits– 80 nutrients, 20+ health benefits
• Revolutionary S.M.A.R.T. delivery system– 12 patents, 2 pending
• Most convenient dosage
