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In America’s heartland, Missouri is transforming itself into a center for biotechnology and sustainable businesses that can help the planet.
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different kind of crop these days—
young companies that are looking to
leave their mark on the world by curing
cancer, feeding the hungry, solving the
energy crisis, and tackling the other
critical challenges facing the planet.
The entrepreneurs behind these
fledgling firms are dreaming big.
They’re also getting lots of support
from state and local government, as
well as from Missouri’s leading universi-
ties and prestigious research institutes.
The resulting spirit of collaboration and
innovation is luring companies from
high-profile states like California, New
York, and South Carolina, and even
some from countries as far away as the
United Kingdom and Israel.
Consider Immunophotonics, a small
company that has developed a minimally
invasive laser-assisted vaccine designed
to treat metastatic breast cancer. A
year ago, the company moved into the
University of Missouri’s brand-new Life
Science Business Incubator in Columbia,
where $300 a month buys furnished
work space, shared office equipment,
and access to mentoring resources. “We
moved into the incubator to take this
to FDA approval in the U.S.,” says chair-
man and CEO Tomas Hode, a Ph.D. from
Sweden who founded the company. In
moving to Missouri, he got not only af-
fordable office space but also financing,
mentoring, and room to grow. “I am
very, very happy here,” he says.
Take a 30-minute drive from Colum-
bia, and there’s Soy Labs, a onetime
California company. It will soon be the
first tenant in the Missouri Plant Sci-
ence Center, now under construction in
the small town of Mexico. In addition
to office and lab space, the center will
include a pilot manufacturing plant de-
signed to help companies easily move
from the lab into initial manufacturing.
And that, says Soy Labs president Ryan
Schmidt, means his fledgling company
will be able to get its product to market
without first investing in its own labora-
tory or production plant.
“It would cost us easily 50% to 80%
more to do this same work in California,”
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If the words “heartland” and “cutting edge” don’t seem to have much in common, think again and take a hard look at Missouri. Along with its traditional harvest of corn and soybeans, Missouri is growing a very
Missouri ranks second in the nation in the
nuMber of farMs.
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says Schmidt, whose company develops
cholesterol-reducing soy products that
can be added to supplements, foods,
or beverages. He expects to have 20
employees on-site within nine months,
and hopes to eventually build a plant in
the 70-acre business park that abuts the
center. “If you can grow companies and
grow entrepreneurs in this down econ-
omy,” he says, “just wait until the econ-
omy turns around to see what happens.”
Homegrown Success Stories
Missouri—which proudly touts its nick-
name, “The Show-Me State”—takes this
culture of entrepreneurship seriously.
Studies show that business startups
play a major role in job creation, in
some areas providing as much as 12%
of employment, according to the Kauff-
man Foundation, a Kansas City–based
organization devoted to entrepreneur-
ship. The state has only to look at some
of its own success stories to see what
can happen.
Express Scripts, for one, started in
1986 with the innovative idea of provid-
ing mail-order pharmacy services. “Our
founder looked at millions of patients
taking maintenance medications for
chronic diseases, and he wondered why
they were being forced to drive to a
pharmacy every 30 days,” says CFO Jeff
Hall. For the next 25 years, the company
implemented a series of breakthrough
methods that continue to make the use
of prescription drugs safer, more ef-
fective, and more affordable. With its
commitment to R&D, Express Scripts,
now headquartered on the campus of
the University of Missouri–St. Louis, has
flourished. Revenues in 2009 reached
$24.7 billion, and they are projected to
exceed $40 billion in 2010.
The impact on the state’s economy?
When you add up Express Scripts’ pay-
roll, the business it does with local sup-
pliers, capital investment, charitable
contributions, and taxes, the amount
that the company contributes to Mis-
souri totals nearly $1 billion a year. And,
after opening its multimillion-dollar
Technology & Innovation Center this
past year, Express Scripts’ positive eco-
nomic impact on Missouri should con-
tinue to grow. It’s a story that the state
is anxious to replicate, and it’s work-
ing hard to do just that. Building on its
diverse agricultural base, the state is
helping launch companies that can take
advantage of Missouri’s great natural
resources, world-class universities, out-
standing quality of life, and supportive
business environment.
Missouri uses a traditional toolbox
of tax credits, tax rebates, and govern-
ment grants to attract companies to
the state. But there’s more. The state
receives a spotless AAA bond rating
from all three rating agencies, and for
the past two years it has balanced its
budget without raising taxes. In a CNBC
rating of states with the lowest cost of
doing business, Missouri ranks fifth.
These days the state is finding that
some of its strongest appeal comes
from Missouri’s community approach to
problem-solving, its collaborative spirit,
and its willingness to think outside the
box. This penchant for innovation and
independent thinking is clear in the
initiatives designed to chart the state’s
future economy.
One of the most ambitious is
Missouri’s Strategic Initiative for Eco-
nomic Growth. Launched this summer
by Governor Jay Nixon, its stated pur-
pose is to transform the state’s economy
in the next five years. “We want to be
proactive, not reactive,” says Nixon of
the project, which will ultimately iden-
tify the six or eight initiatives that hold
the most promise for Missouri. “We
need to know where we are going if we
are going to get there.”
The project—business-led and data-
driven—is moving fast. With a 41-mem-
ber steering committee comprising busi-
ness, industry, labor, civic, and education
leaders, the initiative has garnered
broad support. Its final report is due on
the Governor’s desk by March 31.
Such aggressive pursuit of business in-
novation isn’t a surprise to Missourians.
After all, this is the state that launched
the Lewis and Clark expedition and gave
birth to the Pony Express. Missouri is
the state that invented the ice cream
cone and built the space modules used
kansas city skyline, highlighted by the
historic union station.
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in the Gemini and Mercury space proj-
ects. These days, it’s home to a growing
number of scientists who are splitting
genomes, creating new energy frontiers,
and changing the face of agriculture.
Sustainable Agriculture
In the eastern part of the state near
St. Louis, the emphasis is on plant sci-
ences. It is here that the prestigious
Danforth Plant Science Center is work-
ing to develop new varieties of crops,
ranging from cassava with improved
nutritional qualities to disease-resistant
and drought-tolerant plants, and new
biofuels to create a sustainable energy
source, as well as ways to reduce pesti-
cide and fertilizer use.
“Our goal is to improve nutrition,
end starvation, preserve the environ-
ment, and build St. Louis as a center for
plant science,” says William H. Danforth,
chairman of the center named for his fa-
ther. “If you don’t have something great
in your community, you don’t have a
great community.”
Next door to the Danforth Center, a
new bioresearch park is attracting young
plant-science firms. Across the street
from the center is Monsanto, the former
chemical company that has remade itself
by focusing on agriculture. Along the
way, it has become a major force in the
search for new ways to make agriculture
more sustainable. Its sprawling 500-acre
facility is filled with scientists who take
that charge seriously.
Given the projections for world
population growth, agriculture has a
big job—doubling food production by
2050, says Brett Begemann, Monsanto’s
executive vice president of global seeds
and traits. “And we’ll have to do it on
the same amount of land and with fewer
resources.” The company is doing its part
to address these challenges by develop-
ing better tools for farmers, including
advanced hybrid and biotech seeds.
Still, getting the world to see the
potential provided by new agricultural
innovations can be challenging. “People
don’t understand how significantly
farmers could improve their lot by sim-
ply using hybrid seed,” says Begemann.
Example: In three short years, the intro-
duction of hybrid corn seed transformed
Malawi from a country where people
were starving to one that is now export-
ing its own corn.
Animal Kingdom
In the western part of Missouri, the fo-
cus shifts from plants to animals. Once
home to the Kansas City Stockyards, this
region has now positioned itself as the
nation’s animal health center, produc-
ing everything from animal vaccines
and veterinary supplies to livestock feed
and pet products. Some 32% of the $19
billion global animal health industry is
based in the Kansas City area, making it
the largest single concentration of ani-
mal health companies in the world.
Why Kansas City? Located in the geo-
graphic center of the U.S., the Kansas
City region is within 350 miles of 45%
of all the country’s feedlot cattle, 40%
of its hogs, and 20% of its beef cows
and calves. The region has five veteri-
nary schools located within a 300-mile
radius. In 2007, the U.S. Animal Health
Association moved its headquarters to
nearby St. Joseph after decades in Vir-
ginia. Small surprise, then, that the re-
gion boasts such well-known brands as
Advantix, Beneful, and Greenies, as well
as companies like Switzerland’s Nestle
Purina Petcare and Israel’s Teva Animal
Health Inc. “A very large part of the
global industry is sitting right here,” says
George Heidgerken, president and CEO
of animal health company Boehringer
Ingelheim Vetmedica Inc. and chairman
of the advisory board for the KC Animal
Health Corridor.
Then there are the biomedical
companies. Some have their roots in
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greenhouses at the donald danforth
Plant science center, st. louis.
Missouri ranks third in the small Business and entrepreneurship Council’s energy Cost Index 2010, which measures where the 50 states stand in terms of how major energy costs affect small businesses, individuals, and families.
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state fact file:
• Missouri was named after a tribe whose name meant “town of the large canoes.”
• Missouri was the first state to free its slaves.
• the state boasts more than 95 wineries, which have an economic impact of more than $700 million a year.
• the state nickname—“the show Me state”—was coined in 1899 when Congressman Willard Duncan Vandiver stated: “I’m from Missouri and you’ve got to show me.”
• Walt Disney, who grew up in Marceline, based Disneyland’s Main street UsA on that town.
• Rock Port, with a population of 1,300, is the first city in the U.s. to be powered by wind.
• Branson, located in south-east Missouri, boasts more
theater seats than the Broad-way theater district in new York.
• In 2010, Missouri celebrated the 175th anniversary of Mark twain’s birth, the 125th an-niversary of his work Adventures of Huckleberry Finn, and the 100th anniversary of his death.
• the agricultural sector accounts for 13.3% of the state’s gross product.
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genome-sequencing projects at the
universities; others have sprung from
Missouri hospitals. Still others have ar-
rived from outside the state to capital-
ize on Missouri’s research capabilities
and incubator support. The collabora-
tive approach to both science and eco-
nomic development translates into lots
of room for translational science, which
means that breakthroughs in one disci-
pline can easily be applied in another.
At Washington University, located
at the western edge of Forest Park in
St. Louis, that kind of interdisciplinary
approach is hardwired into the curricu-
lum. Students are encouraged to take
courses in any of the university’s various
schools, and it’s not uncommon to find
a biology major minoring in music or
a student in the art school graduating
with a dual major in economics.
Then there is the university’s Skan-
dalaris Center for Entrepreneurial Stud-
ies. While located within the business
school, it funds and coordinates courses
across all schools and programs at the
university. Every year, it awards more
than $200,000 in seed money for com-
mercial and nonprofit ventures. Recent
winners include a customized earbud
company, a DNA sequencing lab, a loca-
vore food market, and a group that uses
ballroom dancing to build self-esteem
and confidence among fifth-graders.
With about 6,000 full-time under-
graduates and 5,600 full-time students
in graduate and professional programs,
Washington University has also been a
magnet for talent. “We have become
one of the major importers of human
resources in the state,” says Chancellor
Mark S. Wrighton. “Approximately 90%
of our students come from outside Mis-
souri, and about 30% remain in the re-
gion after graduation.”
Incubating Breakthrough Ideas
At the University of Missouri system,
new policies are helping the four-
campus system aggressively tackle the
challenge of growing new companies.
A few years ago, the system expanded
its stated mission to include economic
goods roll off the line in a Missouri Plant.
Missouri is located
near the country’s geo-
graphic and population
centers and is a virtual
“next-door-neighbor”
to at least 20 states.
The state’s proximity
also allows for effi-
cient “quick shipping”
to markets all over the
world. The state has
been ranked as one of
the best for manufac-
turing and logistics.
Missouri has the 7th
largest highway system
in the U.S., two of the
largest rail terminals,
and more than 1,000
miles of waterways.
The state is a hub of
business activity, with
more than 160,000
tons of cargo and 20
million airline passen-
gers transported by air
each year.
Within 500 miles of:
• 44% of U.s. population
• 38% of U.s. personal income
• 45% of total U.s. households
• 46% of total U.s. manufacturing capacity
Missouri’s Central Location
500 Miles
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development, and ever since it has been
overhauling the way it develops, at-
tracts, grows, and invests in fledgling
businesses. “We color outside the lines,”
says Mike Nichols, vice president of re-
search and economic development.
On one front, the university sys-
tem—which has nearly 70,000 students
on its four campuses—has revamped
some longstanding practices to make it
easier to attract talent. Most recently,
it changed its rules to allow students to
own outright any intellectual property
they develop while in school. It also takes
a generous approach to its faculty inven-
tors, letting them keep one-third off
the top of any revenues produced by a
technology that the university chooses to
commercialize. Then it reinvests a signifi-
cant portion of what’s left in the inven-
tor’s department.
The university system also took aim
at the state’s Sunshine Law, which re-
quired its public-private partnerships and
collaborations to be transparent to the
public. That law was making it nearly im-
possible for the university to work with
companies concerned about revealing
business plans, financial information, or
trade secrets that could endanger their
competitiveness, Nichols says. This sum-
mer, Senate Bill 733 revised that law,
leveling the playing field between public
and privately funded institutions.
The university has even begun making
direct investments in startup companies.
This year, some $600,000 was available
for fast-track faculty projects—inventions
that needed a bit more money to see if
they could be commercialized. There is
also a brand-new $5 million seed-capital
fund for direct investment, which Nich-
ols sees as offering the state big returns.
“We’re not looking to make money.
We’re looking to create jobs,” he says.
The result is more small companies
populating a growing number of uni-
versity-affiliated high-tech incubators
that are designed to foster growth in
plant science, animal health, biomedical
innovations, and other attractive areas.
“I feel like a kid in a candy store,” says
Nichols, who spent 25 years launching
new companies before joining the uni-
versity. “I get to leverage other people’s
money, make money for them, and teach
others how to do it.”
These incubators offer the commu-
nity more than just job generation. At
the Christopher S. “Kit” Bond Science
and Technology Incubator in St. Joseph,
Missouri ranks fifth in the tax foundation’s Corporate Income tax Index, which looks at the impact of each state’s principal tax on business activities within the state.
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Gary Clapp runs a unit that’s located on
the Missouri Western State University
campus. He also teaches a course on
bio-manufacturing that’s designed to
provide real-world experience to college
students so they understand of the rules,
regulations, and restrictions that apply
when bringing a product to market.
As head of the Institute for Indus-
trial and Applied Life Sciences, Clapp also
has worked with the local school district
to get more math and science into the
classroom. Yet Clapp says workforce de-
velopment is something that needs to be
addressed even before kids start school.
Citing new programs that target the pre-
school population, he says, “Training has
to begin as soon as a family gets started.”
Supporting Fledgling Entrepreneurs
In Independence, an old hospital is in
the process of being transformed into
an incubator that will feature not only
scientific wet labs but also kitchen work-
space. The Ennovation Center, owned
by the Independence school district, is
aimed at attracting young companies.
But in renovating the building, the de-
signers have kept in mind the impor-
tance of science education. In convert-
ing an old surgical suite into a lab, they
retained the viewing area that once let
visitors watch operations. “We call this
our Grey’s Anatomy suite,” says Tom
Lesnak, president of Independence Eco-
nomic Development, noting that stu-
dents will now be able to watch chemi-
cal experiments without being exposed
to chemicals or fumes.
Job Momentum in Missouri
0 10 20 30 40 50 60 70 80
0 10 20 30 40
65.7%
23.3%
11.0%
Companies were asked: over the next 12 months, does your business plan on increasing, maintaining, or decreasing your current employment levels?
Maintaining
increasing
decreasing
source: Meric Missouri business survey 2010
Monsanto and Vine Design® is a registered trademark of Monsanto Technology LLC. ©2010 Monsanto Company.
We’re Proud to CallMissouri Home
Producing More. Conserving More. Improving Lives. That’s sustainable agriculture. And that’s what Monsanto is all about.
Learn more at www.monsanto.com
Monsanto is a global leader in agricultural innovation.
We work with farmers to produce more crops for a growing world
while conserving more natural resources for future generations.
Headquartered in St. Louis, we are committed to improving lives in
communities where we operate. That’s why we donated nearly $6
million last year to the St. Louis region and its charities through the
Monsanto Fund.
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historical snapshots:
• the Pony express, born in st. Joseph in 1860, improved communications across the country by shortening mail delivery from st. Joseph to sacramento, Calif. the fastest trip made during the compa-ny’s brief 18-month history: seven days and 17 hours.
• Born a slave, Missouri native george Washington Carver
discovered 300 uses for peanuts. the agri-cultural chemist
also developed a crop rota-tion system for southern cot-ton farmers that made use of soil-enriching plants such as peanuts, soybeans, sweet po-tatoes, and pecans.
• In the early 1870s, Adolphus Busch was the first Ameri-can brewer to adopt the use of pasteurization, allowing beer to be shipped long distances with-out spoiling. he also pioneered the use of artificial refrigera-tion, refrigerated rail cars, and rail-side icehouses.
• the 10-story Wainwright Building, designed by Louis sullivan and built in 1891, is considered the world’s first skyscraper. still standing in downtown st. Louis, the building marked a turning point in building design due to its load-bearing steel framework.
• food firsts are common: the ice cream cone was re-portedly invented at the st. Louis World’s fair in 1904. other iconic Ameri-can foods—including the hot dog, Dr Pepper, cotton candy, and iced tea—were popularized at the fair. Aunt Jemima’s pancake flour, in-vented in st. Joseph, was the first ready-mix food to be in-troduced commercially.
• the University of Missouri opened the world’s first school of journalism on sept. 14, 1908. By the end of the day students and faculty edi-tors had published its first newspaper.
• McDonnell Aircraft, which later merged with
Boeing, built space cap-sules for Project Mercury,
the first U.s. manned space program, as well as for Project gemini.GoToStLouis.org
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25 Colleges and Universities
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18th Largest Metro
• Express Scripts • Emerson Electric • Monsanto • Ameren
•Reinsurance Group of America • Charter Communications
• Peabody Energy • Smurfit-Stone Container • Graybar Electric • Centene • Energizer Holdings
• Ralcorp Holdings • Jones Financial • Arch Coal • Brown Shoe
• Sigma-Aldrich • Patriot Coal • Solutia • Laclede Group •
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ADVERTISEMENT
Making Missouri Healthier—Physically and Financially
With 400 locations and nearly 22,000 co-workers and physi-
cians across the state, Mercy touches the lives of approxi-
mately 1.8 million Missourians each year. As an employer,
Mercy provides approximately $104 million in payroll each
month to build stronger families and local economies. The
economic benefit of Mercy in the St. Louis area alone has
been estimated at $2.2 billion in 2009.
$450 Million Electronic Health Record Investment Improves
Patient Experience
Mercy joins just 2.6% of providers nationwide (including Johns
Hopkins and Mayo Clinic) that use an electronic health record
to its fullest. Each day, doctors and caregivers place an average
of 60,000 orders for care and track over 30,000 medication
administrations, improving safety and outcomes for patients.
New Personal Health Record Empowers People to
Better Manage Health
MyMercy, an online connection with a personal physician,
opens up unlimited possibilities in managing health. With
the right information and a convenient connection to their
doctor, people can make smarter decisions and live more
productive lives.
Nation’s Largest Single-Hub Electronic ICU Extends Care
to Remote Hospitals
Mercy’s SafeWatch program brings specially trained physicians
called “intensivists” to over 400 ICU beds in four states. Based
in St. Louis, SafeWatch represents the future of telemedicine;
it provides extra support and expertise to a patient’s bedside
care team in remote hospitals.
$60 Million Data Center Processes Two Terabytes of
Information Every Second
Mercy chose Washington, Mo. from more than 20 sites in the
Midwest to build its data center. The center supports Mercy’s
clinical and operational functions across four states. Built on
Missouri bedrock, it can withstand a variety of
natural events—including a tornado with 157-
mph winds. With a 99.99% availability of data
and files, its backup systems ensure that doctors
and clinicians can continue to serve patients.
Springfield Distribution Center Facilitates
Supply Chain Operations
Mercy’s supply chain operating division, Resource Optimization
and Innovation (ROi), processes 2.1 million pick commands per
year from its warehouse. ROi returned over $22 million in net
financial benefit to customers in fiscal 2009 and was ranked
second in the world in the AMR Research Healthcare Supply
Chain Top 25 for 2009, just behind Johnson & Johnson.
Mercy Partners with Employers to Reduce Expenditures
Holding the cost of employee health benefits to half the national
average is a big win for a large employer in Springfield, Mo. who
partnered with Mercy. Mercy’s ongoing education and health
programs help employers control costs and manage health.
154 Years of Firsts, Pioneered by the Sisters of Mercy
For a century and a half, the Sisters of Mercy served Missouri by
providing hospitals and nursing training where there were none.
Following in the Sisters’ footsteps, Mercy continues to innovate
today by listening and meeting the needs of people in the
Midwest. Mercy is delivering a new model of care
and bringing the future of health care to Missouri.
To learn more about Mercy, visit mercy.net.
Mercy Delivers the Future of Health Care
the Mercy safeWatch teaM Monitors over 400 icu Patients in four states froM its coMMand center in st. louis.
the online ser-vice MyMercy lets Patients contact their doctor and Manage their health When it’s Most convenient.
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Education was also a consideration in
renovating the hospital kitchens, which
now serve as a leasable culinary work-
space. Fully renovated, the area is divided
into five kitchens and boasts $250,000 of
new cooking equipment ranging from
ovens to mixers to a smoker. Already be-
ing leased to tenants who need space to
develop products and start production, it
will eventually house a culinary arts edu-
cation program, as well.
“This is so much fun,” says the kitch-
en’s first tenant, Jennifer Ward, as she
was running a test batch of gluten-free
cookies through the new rotating con-
vection ovens. For Ward, the incubator
is a way to build her business; to Lesnak,
it’s a way to build a community. “Sta-
tistics show that 85% of all incubator
companies stay in the community where
they started,” he says.
Recognizing the importance of edu-
cation to workforce development, the
state has worked hard to make college
more accessible. Govenor Nixon and the
state’s public higher education institu-
tions—including both two-year and
four-year colleges—agreed to freeze
tuition for the past two years despite
challenges posed by the economy. As a
result, this fall, total enrollment in the
state’s public universities and colleges
topped 255,000—an increase of more
than 10,000 students over last year.
Developing a Talent Pool
Corporations, too, are playing a key role
in workforce development. The state
has been working hard to not only ask
employers to identify the kinds of skills
they view as necessary for their contin-
ued growth, but also to create those
programs in the state’s universities, col-
leges, and two-year schools.
Boeing is a prime example. The
aerospace giant’s defense, space, and
security unit is headquartered in St.
Louis, where it produces products rang-
ing from tactical aircraft to unmanned
systems. In 2007, it launched a program
with the State of Missouri and St. Louis
Community College to retrain people
for sheet metal assembly. “It is an in-
credibly productive relationship,” says
Dennis Muilenburg, president and CEO
of Boeing Defense, Space & Security.
“This program trains individuals in the
key skills needed for the aircraft assem-
bly process.”
Boeing also partners with Washing-
ton University and Missouri University of
Science and Technology, offering its em-
ployees continuing engineering courses
that build its talent pipeline. And the
training connection goes even deeper.
“We invest in all tiers of the education
system,” says Muilenburg, noting that
one of his favorites is a high school FIRST
robotics competition. “We actually have
a couple of engineers working for us
who were part of that program.”
Edward Jones, too, has found the
state to be a place where the spirit of
collaboration ranges from lofty goals
like training the workforce to nuts-and-
bolts business development. Founded
in 1922, the financial services firm has
grown over the years and recently over-
saw a significant expansion that hinged
in part on the state’s willingness to
accelerate replacement of a key inter-
change off Interstate 270.
“In Missouri, there is a real and
widespread understanding of the value
and necessity for a good business en-
vironment,” says Jim Weddle, Edward
Jones managing partner. “As a result,
the state, the region, and localities co-
operate. They recognize that working
together they can achieve far more than
working apart. This cooperation drives
economic development. “
Some see Missouri’s pioneer past
a boeing eMPloyee building a fighter jet
in st. louis.
Missouri ranks fifth in the cost of doing business in America’s top statesfor Business, an index compiled by CnBC that is based on each state’s tax burden on individuals, property, and business, as well as utility and energy costs.
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SPECIAL ADVERTISING SECTION
ameren Missouri serves 1.2 million electric and 126,000 natural gas customers in 63 counties and 500 towns. Part of st. louis-based ameren corp. (nyse: aee), ameren Missouri is critical to the state’s economy. its electric rates are about 33% below the national average, while it has invested more than $1 billion in infrastructure proj-ects to ensure that Missouri’s grid, power plants, and pipelines are safe, reliable and environmentally sound. in addition, ameren Missouri’s economic development professionals offer a portfolio of value-added programs, and expertise for com-panies interested in expanding or moving their operations to Missouri. learn more at amerenMissouri.com.
for more than 25 years, states have relied on centene corp. to provide health care services and programs to its most vulnerable and underserved residents. centene has been proud to call Missouri home to its corporate headquarters for the past decade, benefiting greatly from the pioneering spirit so deeply ingrained in our state’s history. the innovative solutions that we continue to develop allow us to remain true to our founding belief—that every american is entitled to receive quality health care with dignity. the friendly economic climate and unparalleled professional talent in Missouri have been invaluable in helping us achieve our mission.
A Powerhouse for Missouri
health Care for the Underserved
Missouri Dept. of Economic Development ded.mo.gov
The Missouri Partnership fortune.MissouriPartnership.com
Ameren amerenMissouri.comAnheuser-Busch anheuser-busch.com
Boeing boeing.com
Centene Corporation centene.com
Edward Jones edwardjones.comExpress Scripts express-scripts.com
Kansas City Area Development Council thinkkc.com
Monsanto Company monsanto.com
Sisters of Mercy Health System mercy.net
St. Louis Regional Chamber & Growth Assoc. gotostlouis.org
University of Missouri System, Research and Economic Development
umsystem.edu/redmapWashington University in St. Louis
wustl.eduWebster University
webster.edu
Web Directory
470 E. Lockwood Avenue • St. Louis, MO 63119
“Webster University was formed by a progressive, committed, inclusive and entrepreneurial community of educators. While the University has changed over time, the values and commitments formed at the outset have endured. They guide us and mark us as those who care, who respond, who innovate, who lead.”
Dr. Elizabeth (Beth) StroblePresident
United States • Austria • China • the Netherlands • Switzerland • Thailand • United Kingdom
webster.edu
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reflected in the way the state and its
companies are tackling economic issues
today. Mercy, a four-state health care
ministry based in St. Louis, has just fin-
ished a decade of infrastructure build-
ing. Faced with big changes in health
care and aging systems, Mercy rolled
up its sleeves and performed a major
overhaul. The result: a brand-new elec-
tronic health record system, a new data
center, a state-of-the-art supply chain
that tracks everything right down to
a bandage as it arrives at the patient’s
bedside, and a fast-growing telemedi-
cine operation.
The health care frontier today may
look different than it did to the pioneer-
ing nuns who founded the health minis-
try more than 150 years ago. But the com-
mitment to getting the job done through
hard work and vision is much the same.
“This makes us sustainable going for-
ward,” says Lynn Britton, president and
CEO of Mercy. “And this is just the start.”
Innovation in Missouri, however,
isn’t just about starting new companies.
It’s also about helping established com-
panies looking for new and better ways
of doing business. At Anheuser-Busch,
for example, there’s a long history of
embracing technology as a way of im-
proving business. More than a century
ago, the company revolutionized the
beer business by adopting pasteuriza-
tion, artificial refrigeration, refrigerated
railcars, and railside icehouses.
“Our founders transformed the U.S.
beer industry and instilled a passion for
innovation that continues to drive our
company,” says president Dave Peacock.
These days the company is turning to
technology to make its breweries greener
and more environmentally friendly.
Since the end of 2004, Anheuser-Busch
breweries have reduced water usage by
nearly 32%, saving 23 billion liters of
water. The company now recycles 99.4%
of the solid waste generated in the
brewing and packaging process, includ-
ing aluminum, glass, grain, scrap metal,
and cardboard.
The company has also embraced al-
ternative energy in a big way, including
the use of solar power at two brewer-
ies and bio-energy recovery systems at
10 breweries, which use nutrient-rich
wastewater from the brewing process
to create and capture renewable fuel.
International Aspirations
On another front, Missouri is taking a
more global view of the world these
days. It has been forging overseas con-
nections in countries ranging from Mex-
ico to Japan, and it’s working to boost
exports and attract foreign companies to
the state. One of its most publicized ef-
forts has been the campaign to establish
a China hub at the Lambert–St. Louis Air-
port. Toward this end, Webster Univer-
sity president Elizabeth Stroble was one
of those accompanying a recent Missouri
delegation to China. Her school, which
boasts 108 campuses worldwide, has had
a working relationship with the Chinese
ministry of education for years. And
that, Stroble says, gave her some insight
into the Chinese interest in St. Louis.
“I see the cargo hub as a way to es-
tablish the kind of relationship with
Missouri has 90 Wineries and 1,500
acres devoted to graPes.
Missouri boasts a total 131,100 green jobs in both direct and support positions. they account for 4.8% of employment within the state.
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China that is a win-win,” says Stroble.
Part of the Chinese attraction to Mis-
souri, she says, is its excellent education
system. And she is quick to point out
that Webster not only has campuses in
China but also houses one of the Chi-
nese government’s Confucius Institutes
on its home campus in Webster Groves.
One of only 362 in the world, the Insti-
tute promotes better understanding of
Chinese history, language, and culture.
Is Missouri a hard sell to the Chinese?
What about to New Yorkers or Cali-
fornians, or those eyeing the research
parks of the Southeastern states? Trans-
plants often say they weren’t sure about
Missouri until they arrived but were
happily surprised by what they found.
Tariq Shah, whose company
PetScreen opened an office in Columbia
last year, initially thought he’d be set-
tling in New York State. The U.K.-based
company wanted to tap into the U.S.
pet population. “There are more dogs
in the U.S. than there are people in
England,” he explains. But the company
opted for Columbia because “the situa-
tion was too good to resist.”
When Shah told his wife they were
heading to Missouri, the first thing she
did was check out Columbia on Wiki-
pedia. A visit last July sealed the deal.
What the Shahs found in Missouri was
an affordable lifestyle—the state has
the fifth-lowest cost of living in the
country—friendly people, and a sense
of community.
There’s also a lot to do. Not only does
the state have two urban centers—St.
Louis in the east and Kansas City in the
west—but each city also boasts its own
sports teams, symphony, theaters, and
museums. Across the state, there are
caves for spelunking, streams for fishing,
lakes for boating, and lots of state parks
for biking, hiking, and birdwatching. The
state’s wineries—while not well known
outside of Missouri—have a long history
and a loyal following. And those inter-
ested in history have their choice of such
attractions as Civil War reenactments,
Harry Truman’s home in Independence, or
the Pony Express Museum in St. Joseph.
Missouri also feels like a place where
a person can make a difference. Stop
by the Midwest Research Institute, a
not-for-profit research organization in
Kansas City, and you’ll get a sense of
the future. The institute tackles applied
science issues ranging from analyzing
anti-cancer drugs to engineering ro-
botics for defense. Some of the most
exciting work is being done in the field
of energy, where algae oil and biomass
are showing great promise, particularly
when combined with other technolo-
gies such as CO2 capture.
With Missouri’s wealth of resources—
water, fields to grow biomass, and loads
of scientific talent—the possibilities
stretch the imagination. “When all those
things are linked, that will make this the
epicenter of some of the most exciting
development in the country,” says Roger
Harris, associate vice president and direc-
tor of energy and life sciences.
Governor Nixon says one recent trip
to a southern Missouri farm exemplifies
his state’s potential for innovation and
growth. He visited the soybean fields of
Kip Cullers, near Stark City, in October
to present Cullers with the Governor’s
Award for Agricultural Achievement.
Cullers had set a new world record
for soybean yields: 160.6 bushels per
acre. That tops the previous world re-
cord—also set by Cullers, in 2007—of
154.57 bushels. Cullers attributes his
success to his use of the latest advances
in scientific research and development;
a keen eye for detail; and old-fashioned
Midwestern elbow grease. He walks his
fields multiple times a day to make sure
his plants are growing in the most con-
ducive environment possible.
“Kip Cullers and farmers across Mis-
souri exemplify our future of innovation,
science, and progress,” Govenor Nixon
says. “They build on our state’s tradition
of agriculture and farming, but they’re
embracing science and technology to
expand their operations in the 21st cen-
tury. That’s exactly the innovative spirit
that will move every part of Missouri’s
economy forward.” —Lynn asinof
to advertise in our economic development sections, contact Pete franco at 212.522.4227. for reprints, call Pars at 212.221.9595, ext. 437.
nelson-atkins MuseuM of art, kansas city
Missouri offers newcomers the fifth-lowest cost of living in the country, plus friendly people and a sense of community.
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Missouri’s economy:fourth Most Diversified of All 50 states
TRADE, TRANSPORTATION, AND UTILITIES
FINANCIALACTIVITIES
MANUFACTURING
GOVERNMENT
INFORMATION
CONSTRUCTION
LEISURE AND HOSPITALITY
OTHER SERVICES OTHER NATURAL RESOURCES AND MINING
EDUCATION ANDHEALTH SERVICES
PROFESSIONAL ANDBUSINESS SERVICES
source: u.s. bureau of econoMic analysis
the brookings institution named the 18-county kansas city region one of the 20 strongest u.s. metros surviving the current economic recession, based on em-ployment and gnP. Want to find out why? visit thinkkc.com for general market in-formation. visit kcsmartPort.com to learn how kc is ideal for distribution and ware-housing. go to kcanimalhealth.com for information on the world’s largest concen-tration of animal health industry assets. visit kcadvancedenergy.com to review kc’s advanced transportation, wind en-ergy, biofuel, and engineering assets. go to kcnext.com to connect with kc’s it industry. get details on kc’s career and lifestyle assets at liveWorkkc.com.
A Center of Innovation
“ It’s no surprise that businesses want to come to Missouri - we have some of the most competitive business and energy costs of any state in the nation. But businesses also want to stay here, want to grow here.
Why? Because they can.”
J A Y N I X O N G O V E R N O R O F M I S S O U R I
3rd lowest business energy costs (Small Business Entrepreneurship Council)
5th lowest cost of doing business (CNBC)
7th best transportation network (CNBC)
WWW.FORTUNE.MISSOURIPARTNERSHIP.COM
MISSOURI DEPARTMENT OF ECONOMIC DEVELOPMENT THE MISSOURI PARTNERSHIP