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Glycolysis and Krebs' Cycle
Grade:«grade»Subject:«subject»
Date:«date»
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1 Which of the following enzymes catalyzes a reaction that produces ATP during glycolysis?
A Hexokinase (HK)
B Phosphoglucose isomerase (PGI)
C Phosphofructokinase (PFK)
D Triosephophate isomerase (TPI)
E Pyruvate Kinase (PK)
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2 Which of the following enzymes breaks one 6-carbon sugar into two 3-carbon sugars?
A Hexokinase (HK)
B Phosphoglucoisomerase (PGI)
C Phosphofructokinase (PFK)
D Aldolase
E Enolase
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3 If a person would be deficient in all three forms of PFK, this person would ___ .
A Have lower than normal glycogen stores .
B Have more mitochondrial activity than normal .
C Be dead .
DProduce more energy per glucose molecule because glycolysis would be unregulated .
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4 Assuming that Dr. Saccharo is correctly assuming that Ann has a defect in glycolysis, what is the most likely defect based on the blood metabolic profile?
A HexokinaseB Phosphofructokinase
C Triosephosphate IsomeraseD Pyruvate kinase
E Aldolase
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5 The muscle biopsy showed an excess of glycogen in the muscle tissues. What is the most likely enzyme deficiency?
A Pyruvate kinaseB Hexokinase
C PhosphofructokinaseD Triosephosphate Isomerase
E Aldolase
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6 If you wanted to test red blood cells for their ability to complete glycolysis, what compound would you try to detect?
A Fructose-6-phosphateB Aldolase
C Pyruvate
D Phosphofructokinase
E Dihydroxyacetone phosphate
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7 If you had some of Marie's red blood cells in a test tube, what compound could you add to enable these cells to produce pyruvate?
A Glucose
B Fructose-1,6,bisphosphate
C Insulin
D Glucagon
E Fructose-6-Phosphate
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8 Identify the substate present at step #8
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9 Identify the product of step #9
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10 Identify the reactant at step #10
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11 Identify the product of step #11
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12 State the total number of ATP produced by substrate-level phosphorylation for each pyruvate molecule that enters the mitochondrion.
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13 State the total number of NADH molecules that are produced per molecule of glucose by the end of the
Krebs cycle.