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    SEMINAR ON ANALYSIS

    OF CALCULI

    PRESENTED BY

    ANU PRASHER

    B.Sc. MLT FINAL YEAR

    MODERATOR

    DR. HARJEET KAUR

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    INTRODUCTION

    An abnormal solid conc. of mineral and Salt formedaround organic material

    Found in cysts and ducts

    Found in bladder, renal pelvis, kidneys & ureter

    Largest stones are found in bladder

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    Small stones are found in renal pelvis, Kidney and ureter

    Can be of varying sizes

    Requires nucleus on which crystals are deposited.

    Its presence can obstruct urinary flow and can cause

    infection and haematuria.

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    Uric acid stones

    Calcium oxalate stones

    Phosphate stones

    Calcium carbonatestones

    TYPES OF STONES

    Cystine Stones

    Xanthene Stones Fibrin Calculi

    Urostealith

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    Uric Acid stones are round or oval

    Uric Acid Stones are almost coloured varying shadesof brown

    They may be single or multiple

    Usually found in patients with gout but also found in

    patients with bladder outflow obstruction.

    They are usually fairly hard & often have a smoothsurface though sometimes they may be rather tough

    URIC ACID STONES

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    CALCIUM OXALATE STONES

    They are found in a majority of calculi usually mixed with agreater or less amount of phosphate

    Oxalate Stones are among the hardest stones found and Soare not easily crushed

    The surface of small oxalate stones is often rough andblood stained

    Oxalate stones is a primary stones that grows slowly,usually it is of moderate size and is solitary

    Sometimes it bristles with spines

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    PHOSPHATE CALCULI

    It may contain either triple phosphate or calciumphosphate

    Calcium phosphate , mixed with calcium oxalate is a common

    finding in patients with hypercalciuria

    Triple Phosphate is deposited when the urine is alkalineand so is usually found when there is infection of urinary

    tract, when urea is converted into ammonium carbonate

    These are among the softest & whitest stones

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    CALCIUM CARBONATE STONES

    Calculi consisting mainly of calcium carbonate are very rarein man but small amounts of the substance can be detected in

    the number of calculi

    Stones containing carbonate tend to be rather hard

    The salt is deposited as carbonate-apatite from alkaline,infected,carbonate rich urines

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    CYSTINE STONES

    These are also rare

    They are usually fairly small and are smooth and waxy inappearance and to the touch.

    They are brownish Yellow or Light green in colour and occur

    in cases of cystinuria.

    The increased cystine excretion is often the cause ofcalculus formation as in case of cystinuria

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    XANTHINE STONES

    They are even rarer than Cystine

    They are Yellowish brown in colour being rather similar touric acid calculi

    They sometimes contains uric acid

    They occour in case of xanthinuria

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    UROSTEALITH

    Urostealith calculi have been reported in bladder

    They are soft and contain a large amount of fat

    They are extremely rare

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    FIBRIN CALCULI

    Fibrin Calculi may form from blood clots

    They are rare but may form the nucleus of other stones

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    Factors causing the formation of Stones

    Certain conditions are recognized as being favourable forstone formation but do not explain the presence of somestones

    It is known that stagnation of urine particularly if there isalso infection present may lead to stone formation

    e.g. in

    Hydronephrosis

    Enlarged prostate

    Bladder Infection Hyperparathyrodism

    Hypervitaminosis D with excessive mobilization anddeposition of calcium are also known to be

    accompained by formation of calculi

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    URINARY CALCULI

    These may be found in any part of urinary tract like kidney,renal pelvis, ureter.

    They vary very considerably in size from little more than pinhead to the size of an egg

    The passage of stones down the ureter produces renal colic,which is characterized by serve pain in the back radiating tothe groin region

    Stones may also be passed through the urethera with greatpain

    Hematuria is a common urinary finding when symptoms ofstone are present.

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    KIDNEY STONES

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    GALL STONES

    Substances found in Gall stones are

    Cholestrol Bile Pigments

    Calcium Phosphate and

    Calcium Carbonate

    Cholestrol stones are often white or light coloured,mixed stones are usually quiet dark

    They may be single multiple,large or small.Thosecontaning Ca salts are radio opaque

    Their presence ,however ,predisposes to attacks ofcholecystitis with formation of debris and impairedemptying of the gall bladder

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    GALL BLADDER STONES

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    PANCREATIC CALCULI

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    Salivary Calculi are occasionally submitted forexamination

    They are most commonly composed of calciumphosphate and calcium carbonate with small amountof organic matter

    They are usually formed in the parotid orsubmandibular ducts

    SALIVARY CALCULI

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    SALIVARY CALCULI

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    Enteroliths :-

    It consist mainly of phosphates deposited around anucleus which is often a foreign body such as fruit stone

    Some organic material or faecal pigment are present

    Small enteroliths may also be formed by the

    deposition of phosphate on undigested vegetablematerial

    FAECAL CONCRETIONS

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    Coproliths :-

    Are almost entirely organic containing hardenedfaecal material formed from stationary faecalmatter in colon

    Drug calculi :-Small stones may be formed from drugs which are insoluble or

    only slightly solublee.g.

    Magnesia

    Barium Sulphate

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    MONITORING PATIENTS

    For the common calcium stones, large amounts of fluids andtheazide diuretics are used for treatment

    Thiazides plus and allopurinol are used for patients with

    calcium stones who have increased calcium and uric acid inurine

    Stones resulting from infection contain bacteria and are

    removed surgically and the appropriate fluids and antibioticstherapy instituted

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    THANK YOU


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