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Introduction to the Human Body
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Anatomy- science of structure
- relationships revealed by dissection and imaging techniques
Anatomy and Physiology?
Physiology- science of body functions- includes the study of
homeostasis (keeping the organs
systems of the body in balance)
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Levels of Organization
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Systems of the Human Body• Integumentary System consists
of the skin and related structures
(hair, nails, and glands).– Protects body, regulates
temperature, and eliminates wastes through sweat and other secretions
• Skeletal System consists of the bones and joints.– Provides protection and support
– Houses cells that will become red blood cells, white blood cells, and
platelets
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• Muscular System consists of skeletal muscles, as smooth muscle and cardiac muscle.– With the skeletal system facilitates
movement and maintains posture
– Generates heat necessary for warm-blooded organisms to
maintain a constant body temp.
Systems of the Human Body
• Nervous System consists of the brain, spinal cord, nerves, and sensory
organs).– Senses and responds to body
conditions through
nerve impulses
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Systems of the Human Body• Endocrine System consists of
hormone- producing cells and glands scattered throughout the body.– Regulates the body through
chemical
mechanisms (by releasing hormones into the blood)
• Cardiovascular System consists of the heart, blood, and blood vessels.– Carries blood and nutrients to specific
locations
– Regulates body temperature, and water balance
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Systems of the Human Body• Lymphatic and Immunity System
consists of the lymphatic fluid, nodes, and lymphocytes – and other associated organs of
the immune system - tonsils, spleen and thymus – Transports fats and proteins to the
cardiovascular system
– Filters blood and protects against disease
• Respiratory System consists of the upper airways, the trachea and major
bronchi, and the lungs.– Extracts O2 and eliminates CO2
– In conjunction with the kidneys, regulates acid/base balance
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Systems of the Human Body• Digestive System consists of the esophagus,
stomach and intestines, and the accessory digestive glands like the salivary glands, liver, and gallbladder.– Accomplishes the physical and chemical
breakdown of food and elimination of waste
• Urinary System consists of the kidneys, ureters, bladder, and urethra.– Involved in the collection and
excretion of waste products in urine, and the
regulation of fluid, electrolyte, & acid/base balance
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Systems of the Human Body• Reproductive System consists of the ovaries, uterus and vagina in
the female, and the testes and penis in the male (along with associated organs and glands in both sexes).– Reproduction of an individual or organism
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Essential Life Processes• Metabolism
- Sum of all the chemical process that occur in the body
- Catabolism: the breakdown of complex chemical substances into simpler components
- Anabolism: the building up of complex chemical substances from smaller, simpler
components
• Responsiveness
- Body’s ability to detect and respond to changes
- Decrease in body temperature
- Responding to sound
- Nerve (electrical signals) and muscle cells (contracting)
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Essential Life Processes• Movement
- Motion of the whole body
- Organs, cells, and tiny subcellular structures
- Leg muscles move the body from one place to another
• Growth - Increase in body size
- Due to an increase in existing cells, number of cells, or both
- In bone growth materials between cells increase
• Differentiation
- Development of a cell from an unspecialized to specialized state
- Cells have specialized structures/functions that differ from precursor cells
- Stem cells give rise to cells that undergo differentiation
• Reproduction
- Formation of new cells (growth, repair, or replacement)
- Production of a new individual
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HomeostasisA condition of equilibrium in the body’s internal environment.
Maintaining the internal environment within physiological limits is extremely important.
Homeostasis is continually being disrupted by different stimuli:– external stimuli: intense heat, cold , and lack of oxygen– internal stimuli: psychological stresses, exercise
Disruptions are usually mild & temporary
If homeostasis is not maintained, death may result.
Animation: Communication, Regulation and Homeostasis
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• Body fluid compartments– Intracellular fluid (ICF) - fluid within cells– Extracellular fluid (ECF) - fluid outside cells
- Interstitial fluid – ECF between cells and tissues
ICF
ECF
Homeostasis
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• ECF Types and Locations
• Blood Plasma- ECF within blood vessels
• Lymph- ECF within lymphatic vessels
• Cerebrospinal fluid (CSF)- ECF in the brain and spinal cord
• Synovial fluid- ECF in joints
• Aqueous humor and vitreous body- ECF in eyes
Homeostasis
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• Interstitial Fluid and Body Function
• Cellular function depends on the regulation of composition of interstitial fluid
• Composition of interstitial fluid changes as it moves– Movement back and forth across capillary walls
provide nutrients (glucose, oxygen, ions) to tissue cells and removes waste (carbon dioxide)
Homeostasis
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Control of Homeostasis• Homeostasis is constantly being disrupted
– Physical insults• Intense heat or lack of oxygen
– Changes in the internal environment• Drop in blood glucose due to lack of food
– Physiological stress• Demands of work or school
– Disruptions• Mild and temporary (balance is quickly restored)
• Intense and Prolonged (poisoning or severe infections)
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• Receptor
– monitors a controlled condition
• Control center
– determines next action
• Effector
– receives directions from the control center
– produces a response that changes the controlled condition
Control of HomeostasisFeedback Loops
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Negative & Positive Feedback Loops• Negative feedback loop
– original stimulus reversed – most feedback systems in the body are negative– used for conditions that need frequent adjustment– body temperature, blood sugar levels, blood pressure
• Positive feedback loop
–original stimulus intensified
–seen during normal childbirth
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Feedback Loop Examples
• Positive Feedback Control of Labor
• Negative Feedback Control of Blood Pressure
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Homeostatic Imbalances
• Disorder: abnormality of function
• Disease: homeostatic imbalance with distinct -– Symptoms: changes in body function felt by the patient
such as nausea – Signs: changes in body function that can be observed
by the doctor such as rash or fever
• Diagnosis: skill of distinguishing one disease from another
• Epidemiology: how a disease is transmitted
• Pharmacology: how drugs used to treat disease
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Basic Anatomical Terminology
• Anatomical position
• Regions of the body
• Directional terms
• Anatomical planes and sections
• Body Cavities
• Abdominopelvic regions and quadrants
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Anatomical Position
• Standardized position from which to describe directional terms
– standing upright
– facing the observer, head level
– eyes facing forward
– feet flat on the floor
– arms at the sides
– palms turned forward
• Prone position = lying face down
• Supine position = lying face up
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Regional Terms
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Directional Terms
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Directional Terms
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Body Planes
Sagittal
midsagittal
parasagittal
Frontal/Coronal
Transverse/Horizontal
Oblique
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Body Planes and Sections
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Body Planes and Sections
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Body Planes and Sections
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Body Cavities
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Body Cavities - Thoracic
• Encircled by ribs, sternum, vertebral column and muscle
• Divided into 2 pleural cavities by mediastinum
• Mediastinum contains all thoracic organs except lungs
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Body Cavities - Thoracic
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Abdominopelvic Cavity
• Inferior portion of ventral body cavity below diaphragm
• Encircled by abdominal wall, bones & muscles of pelvis
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Serous Membranes
Membrane on the organ
is called visceral
Membrane on the wall
of the cavity is called
the parietal
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Pleural & Pericardial Membranes
• Visceral pleura clings to surface of lungs --- Parietal pleura lines chest wall
• Visceral pericardium covers heart --- Parietal pericardium lines pericardial sac
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Peritoneum
• Visceral peritoneum --- serous membrane that covers the abdominal viscera (organs)
• Parietal peritoneum - -- serous membrane that lines the abdominal wall
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Abdominopelvic Quadrants and Region
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Medical Imaging
• Allows visualization of structures without surgery
• Useful for confirmation of diagnosis
• Examples:
Radiography Ultrasound (US)
CT PET
MRI Radionuclide scanning
Endoscopy
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Radiography
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Radiography
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Radiography
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Radiography
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Radiography
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Radiography
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Computed Tomography (CT Scan)
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Magnetic Resonance Imaging (MRI)
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Ultrasound (US)
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Positron Emission Tomography (PET)
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Radionuclide Scanning
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Endoscopy