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David PrestiDepartment of Molecular and Cell Biology
University of California, Berkeley
Summer 2008
Topics
brain and nervous system organization atoms, molecules, proteins, lipids, membranes
cells, DNA, genes neurons, ion channels, nerve signaling
synapse, neurotransmitters, neural circuits molecular pharmacology, drugs
seizures brain imaging (PET, fMRI, MEG, etc)
brain development sensation and perception
Topics
vision audition, music taste, smell
somatosensory / tactile movement, paralysis
biological rhythms, sleep, dreaming learning, memory
language mental disorders: depression, psychosis, etc
mind, consciousness
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Textbooks
An Introduction to Brain and Behavior
by Bryan Kolb And Ian Whishaw2nd edition - 2006
The Double Helixby James Watson - 1968Norton Critical Edition
edited by Gunther Stent - 1980
Course Grade
Exams: Two Midterm Exams (online)
Final Exam (proctored)
Homeworks: neuroscience in the news (one)
Double Helixessay composing exam questions
neuroscience in the news (two)
Online Discussion Forum participation
2001: A SPACE ODYSSEY
(1968)
directed by Stanley Kubrickwritten by Stanley Kubrick (1928-1999)
and Arthur C. Clarke (1917-2008)
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Hominid Evolution
hominid = human-like animal
includes modern humans and recent
(circa past 4 million years)
human ancestors
a timeline of hominid evolution
millions of years agoFigure 1-12
time spansare
approximate
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Hominid Evolution
genus Australopithecus
various species have been described:
A. robustus, A. africanus,
A. afarensis, A. aethiopicus
circa 4 million years to 1 million years ago
Hominid Evolution
genus Homo
Homo habilis
circa 2 million years to 1.5 million years ago
Homo erectus
circa 1.6 million years to 200,000 years ago
Homo sapiens
modern humans
circa 200,000 years ago
to the present
only extant hominid species
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Homo neanderthalensis
parallel evolutionary branch of the genus Homo
circa 300,000 to 30,000 years ago
ritual
burial of dead
pet animals
music
ancient music? - circa 50,000 years ago
portion of what appears to be a flute made
from bear bone by Homo neanderthalensisFigure 9-1
brainsizecubic
centimeters(cc)
Figure 1-12
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Killing of conspecifics
hominid human ancestors
~ 4 million years ago
human deaths due to violent conflictin the 20th century
~160,000,000
I refuse to accept the cynical notion that nation after nationmust spiral down a militaristic stairway....I believe that unarmedtruth and unconditional love will have the final word in reality.
Martin Luther King (1929-1968)Nobel Peace Prize acceptance speech - 1964
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Does HAL
have amind?
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What is Mind?collection of mental states
internal, subjective experiences:thoughts
feelings
perceptions
awareness / consciousness
Reading associated with this lecture:
An Introduction to Brain and BehaviorChapter 1
begin readingThe Double Helix