Slide 1

Presented by :

1. Graha Ayu Praptiwi2. Junita Bri Hastuti3. Ruri Oktavianti

Uji Antiinflamasi Daun Jambu Mete (Anacardium occidentale L.) Yang Ditimbulkan Pada Telapak Kaki Tikus Putih JantanAntiinflammatory Activity of The Cashew Leaves On Hind Paw of The Male White Rats

Background &PurposeP1Inflammation is a normal protective response to tissue injury caused by physical trauma, damaging chemicals or substances microbiologyNSAID have been used as anti-inflammatory therapy but have side effect like gastrointestinal distrubances so natural anti-inflammatory is needed.

Powder microscopy of A.occidentale LinnCashew leaves (Anacardium occidentale L.) has nature substances which have anti-inflammatory characteristic like tanin, flavonoid, anakardiol acid , elagic acid, fenol, kardol, methyl kardol, and salisilic acid. Determine the effect of anti inflammation ethyl acetate extract of cashew leaves (Anacardium occidentale L.) on edema in hind paw of Wistar male rats compared with natrium diclofenacMethods of ResearchThis research was a laboratory design using experimental method.

Thirty male white rats (2-3 month) of 100-200 gr were used in this study and divided into 6 groups (5 rats each). P2

Male White RatsMale white rats were fasted for 18 hours and still be drinkingGroup V(EAE III 1,8 g/kg BW)Group IV(EAE II 900 mg/kg BW)Group III(EAE I 450 mg/kg BW)Group II(Na diclofenac)Group I

(aq.dest)Measuring first volume of the hind paw ratsThe induction of inflammation was done by injecting 0,5% carrageenan into the rats pawMeasuring hind paw volume every 30 minutes until 300 minutesThe data will be analyzed with statistically by ANOVA test and DAI testConclusionGroup VI(EAE II + Na diclofenac)RESULT OF THE RESEARCHBibliographiesSutrisna, E.M., Widyasari, Domas., Suprapto, Uji Efek Anti Inflamasi Ekstrak Etil Asetat Buah Semu Jambu Mete ( Anacardium occidentale Linn) terhadap Edema pada Telapak Kaki Tikus Putih (Rattus norvegicus) Jantan Galur Wistar yang Diinduksi Karagenin, Universitas Muhammadiyah Surakarta. Biomedika. 2010 ; II. 1

Nurain, Uji Efek Anti Inflamasi Ekstrak Buah Tomat (Solanum lypopersicum L.) Pada Tikus Putih Jantan, Universitas Sebelas Maret Jakarta. 2010.

Patil, MB,. Jalalpure, SS., Pramod, HJ., Manvi, FV., Anti Inflammatory Activity of The Leaves of Anacardium occidentale Linn. Mumbai, 2003, Vol. 65.

Pawar, S.P, Sathwane, P.N, Metkar, B.R, Pal, S.C, dkk, Anti Inflammatory and Analgesic of Anacardium occidentale Linn Leaf Extracts. PMC. 2000 ; 169-173.

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