Palisades and tumors

Lung metastatic tumor in brain

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A meningioma at a parasagittal location

Benign meningioma growing underneath the dura

Note compression caused by meningioma in the underlying

cerebral hemisphere

Meningioma compressing the pituitary

Giantism can result from pituitary tumors in childhood

Benign ependymoma; note inaccessible site

Cystic astrocytoma of childhood

Glioma with mass effect

Low grade gliomas still have poor prognosis if present in a difficult to remove location

Large brain stem glioma

Cerebral hemisphere glioma; note absence of clear margin

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Astrocytoma at low magnification; normal tissue at

right

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Glioblastoma multiforme

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GBM: note necrosis, hemorrhage

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Note palisading effect around necrotic region

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Two models for the formation of pseudo-palisades in GBM

Palisading cells surrounding necrosis are typical of GBM

Model for formation of palisades