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Shire Adds Hosted Version of IDBS' E-WorkBook to Support 'Virtual Model' for Drug Discovery April 16, 2010

By Vivien Marx

IDBS said this week that biopharmaceutical firm Shire will use

its E-WorkBook Suite to support a "virtual model for

pharmaceutical research."

IDBS is implementing the electronic lab notebook suite as a hosted solution in

collaboration with IT firm Quantix.

Shire will use the hosted E-WorkBook solution in collaborations with contract research

organizations. Because the hosted approach will not require on-site data storage, it will

reduce the IT footprint for both Shire and its CRO partners, IDBS said. The deployment

will give participants access to remote data and will also enable them to streamline

knowledge transfer between organizations.

Shire is a new customer for IDBS, Chris Molloy, vice president of corporate

development for IDBS, told BioInform this week via e-mail.

E-WorkBook is a platform to capture, manage, and share research data. The hosted

solution includes a security model that "addresses concerns around cloud computing"

so multiple CROs and other partners can share data, the company said.

"Shire is pleased to take a leadership role in implementing this emerging business

model of virtualized drug research, which uses new technologies to support novel

working practices, improve collaboration, and speed the exploratory projects research,"

Stephen Damment, senior vice president of biosciences at Shire, said in a statement.

Shire declined to provide further comment.

In this project, Shire and each of its CRO partners will be able to use E-WorkBook in a

slightly different way for the capture, securing, and review of data, Molloy said. They will

"see only the data that they need to, while all the resultant IP remains fully protected

and owned by Shire," he explained.

IDBS said that it has previously implemented a multi-site hosted environment for E-

WorkBook with customers such as Australia's Cancer Therapeutics CRC, where it is

used by separate sites and groups to manage part of an overall research process.

Other undisclosed pharma companies have also implemented E-Workbook this way,

often in configurations with infrastructure-as-a-service suppliers behind the company

firewall, Molloy said.

The implementation is configured in order to "reassure companies that their electronic

collaboration systems will not leak IP to third parties and that their data-management

infrastructure will be able to handle the size and complexity of the growing external

research environment," Molloy said.

Molloy said that since IDBS acquired InforSense last year (BI 7/6/2009), "we have

taken the lead in demonstrating how to successfully integrate industry-leading

[electronic lab notebook] and analytic technologies." For example, he said together the

firms launched the "world's first biomarker ELN" in February and "already have made

multiple sales."

He acknowledged that the merger of Accelrys and Symyx, announced earlier this

month (BI 4/9/2010), will present some competition. Accelrys offers the Pipeline Pilot

workflow software, which competes with the InforSense technology, and Symyx brings

its own ELN to the combined entity.

The merged firms "will still be a strong competitor in some chemistry market sectors but

IDBS remains highly differentiated," he said. "Our breadth of domain understanding,

robust technologies, and ability to be a strategic player in higher-growth markets such

In this issue of BioInform

Biogen Idec Sees Promise in Network Modeling to Identify New Autoimmune Disease Targets

At Network Bio Conference, Speakers Highlight Role of Molecular Methods in Unraveling Cancer's Complexity

VBI Study Indicates Prokaryotic Gene-Finding Algorithms Overlook Hundreds of Gene Families

EBI-Helsinki Team Integrates Array Data from Thousands of Samples to Map Global 'Expression Space'

Next Gen Sequencing

Resource Center

Targeting the Human Exome in Medical

Re-sequencing

Stacy Gabriel, Ph.D

Sequencing technologies—the next generation

Nature Reviews Genetics. 2010 Jan;11(1);31–46. Epub 2009 Dec 8.

Download the Agilent NGS Application

Guide

Young Investigator Profile

Blog

Papers of Note

People on the Move

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Accelrys has appointed Todd Johnson to be executive

VP of sales and marketing services, and that Ilene Vogt

has departed the company and left her post as senior

VP of worldwide sales and services. Johnson joined

Accelrys in 2009 as interim CEO, and after the firm

tapped Max Carnecchia to take the helm, Johnson

stepped into the role of senior VP.

Harvard University Professor Raju Kucherlapati will

serve as an Obama Administration adviser on genetic

and genomic issues in his role as a member of the

Presidential Commission for the Study of Bioethical

Issues.

OncoMethylome Sciences has named Jan Groen to

take over as CEO. Groen formerly was president and

COO of Agendia, and he was VP of R&D at Quest's

Focus Diagnostics subsidiary.

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Page 2: Quantix cloud case study

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No. We're not even close.

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Science

At the American Association

for Cancer Research annual

meeting, National Institutes of

Health Director Francis

Collins and National Cancer

Institute Director John

Niederhuber highlighted

opportunities for researchers

to translate cancer research

into clinical advances.

Business

BioMérieux and Knome will

collaborate on developing

next-generation sequencing-

based molecular diagnostics.

BioMérieux intends to

develop cancer and infectious

disease diagnostics using

Knome's sequence analysis

technology and bioinformatic

tools.

Funding

Genome Canada plans to use

the C$75 million in funding it

will receive under Canada's

2010 budget to support the

purchase of new technologies

and a wide array of research

efforts, which will emphasize

forestry, the environment,

human health, and

agriculture.

Genome Technology Magazine

In this month's Brute Force column,

Matthew Dublin says that while many

people are concerned about the amount

of data generated by next-gen

sequencers, a more pressing concern

might be how to deal with analyzing that

data — especially when considering the

error rates associated with it.

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