Regenerative Medicine &
Stem Cells-2013
Theme: A New Hope for Medical Science
Preliminary Program
Opening Ceremony & Keynote Forum of Global Health Conference-2013
Time: 09:00-12:05,Oct. 12, 2013 Place: Room No.303, 3rd Floor, Dalian International Conference Center
Moderator Dr. John Yu, Distinguished Research Fellow, Institute of Cellular & Organismic Biology and the
Genomics Research Center, Academia Sinica, Taiwan
09:30-09:35 Moderator's Introduction
09:35-10:05
Title: Gene and Stem Cell Therapy for Diabetes - Some Thoughts and Candid Questions
Dr. Roy Yorke Calne, Emeritus Professor, Cambridge University, UK
10:05-10:35
Title: Dietary Supplements: What Consumers Should Know
Dr. Sally Greenberg, Executive Director, National Consumers League, USA
10:35-11:05
Title: Micronutrient Intake and Economic impact of Malnutrition – A Global Perspective
Dr. Eggersdorfer Manfred, Senior Vice-President, DSM Nutritional Products, Switzerland
11:05-11:35
Title: Connected Innovation: The Power of Many
Dr. Bernhard van Lengerich, Chief Science Officer & Vice President, General Mills Inc., USA
11:35-12:05
Title: Aging and Hearing Disorders
Dr. Steven Juhn, Professor and Director, Auditory Biochemistry Laboratory, University of
Minnesota, USA
12:10-13:10 Luncheon
Plenary Lectures
Time: 13:30-16:40, October 14, 2013 (Monday); Place: Room No. 307A, 3rd Floor, DICC
Moderator Dr. John Yu, Distinguished Research Fellow, Institute of Cellular & Organismic Biology and the
Genomics Research Center, Academia Sinica, Taiwan
13:30-13:40 Moderator’s Introduction
13:40-14:10 Title: Mir-302 Contributes to Tumorigenicity through Promoting G1 to S Transition and
Maintaining OCT4 Overexpression by Inhibiting AKT1
Dr. Chunhua Zhao, Director, Center of Excellence in Tissue Engineering, Chinese Academy of
Medical Sciences; Professor, Peking Union Medical College, Chinese Academy of Medical
Sciences, China
14:10-14:40 Title: The Mechanism and Role of MMPs in Soft Tissue Injury and Regeneration
Dr. Kuo-Li Paul Sung, Director and Professor, University of California at San Diego, USA:
Distinguish Professor, Chongqing University, China
14:40-15:10 Title: Stem Cell Marker Lgr5 and its Relatedness with Other Putative Markers of Cancer Stem
Cells in Gastric Adenocarcinoma
Dr. Wufang Fan, Director and Professor, Hebei University, China
15:10-15:40 Title: Stem Cells and Transcription Factors in Oral and Craniofacial Tissue Regeneration
Dr. Jake (Jinkun) Chen, Professor and Director, Division of Oral Biology, Tufts University, USA
15:40-16:10 Title: Functionally Mature Innate-Immune-Ralated Cells Derived from Human Pluripotent Stem
Cells
Dr. Feng Ma, Professor, Chinese Academy of Medical Sciences (CAMS) & Peking Union Medical
College, (PUMC)
16:10-16:40 Title: Immune Modulation by Mesenchymal-like Stromal Cells–Lessons from Clinical Trials
Dr. Hans-Dieter Volk, Director, Berlin-Brandenburg Center for Regenerative Therapies (BCRT),
Charite-University Medicine Berlin, Germany
Track 1: Landscape and Outlook of Global Stem Cell
Session 1-1: Legal, Politics, Ethic, and Social Acceptance of Stem Cell Research
Time: 13:30-15:05, October 12, 2013 (Saturday); Place: Room No. 618, 6th Floor, DICC
Chair Dr. Oktay Kadayifci, Professor, Ob & Gyn and Perinatology, The University of Cukurova; Head,
The Onkim Stem Cell Technologies, Turkey
13:30-13:35 Chair’s Introduction
13:35-14:05 Title: What Can Be Done with the IVF Excess Embryos? Just to Destroy or Use Them for the
Sake of Humanity?
Dr. Oktay Kadayifci, Professor, Ob & Gyn and Perinatology, The University of Cukurova; Head,
The Onkim Stem Cell Technologies, Turkey
14:05-14:35 Title: Lessons from the Vogue for ―Stem Cell Therapy‖ in Inland China: Ethical and Policy Issues
Dr. Renzong Qiu, Emeritus Professor, Institute of Philosophy, Chinese Academy of Social
Sciences; Professor and Chair, Center for Bioethics, Chinese Academy of Medical
Sciences/Peking Medical College, China; Vice-President, National Ethics Committee, the Ministry
of Health, China
14:35-15:05 Title: Legal and Political Debate on Stem Cell Research and Therapy in South Korea
Dr. So Yoon Kim, Associate Professor, Yonsei University, South Korea
15:05-15:30 Coffee Break
Session 1-2: Global Stem Cell and Tissue Engineering Projects
Time: 13:30-15:35, October 13, 2013 (Sunday); Place: Room No. 618, 6th Floor, DICC
Chair Dr. Stefanos Theoharis, Chief Business Officer, apceth GmbH & Co KG, Germany
13:30-13:35 Chair’s Introduction
13:35-13:55 Title: Development of Pharmaceutical Grade Advanced Therapeutics (ATMPs) for the European
& Global Market
Dr. Stefanos Theoharis, Chief Business Officer, apceth GmbH & Co KG, Germany
13:55-14:15 Title: In Vitro Vascularization of 3-D Functional Tissues
Dr. Tatsuya Shimizu, Professor, Institute of Advanced Biomedical Engineering and Science,
Tokyo Women’s Medical University, Japan
14:15-14:35 Title: Industrial Aspects of Allogeneic Mesenchymal Stromal Cell (MSC) Expansion and
Treatment
Dr. Chi-Meng Tzeng, Professor and Executive Director, Translational Medicine Center, Xiamen
University, China
14:35-14:55 Title: Engineering Cell Surfaces for Tissue Assembly
Dr. Muhammad N. Yousaf, Professor & Chair, Department of Chemistry, York University,
Canada
14:55-15:15 Title: Cell Blebbing in Cryopreservation: A Self-Protection Mechanism of Cells
Dr. Weiping Ding, Associate Professor, Centers for Biomedical Engineering, University of
Sciences and Technology of China, China
15:15-15:35 Title: Transvasal and Intrapulmonal Delivery of Autologous Mesenchymal Stem Cells in Patients
with Severe Pulmonary Arterial Hypertension
Dr. Aris Lacis, Head, Clinic of Pediatric Cardiology and Cardiac Surgery, University Hospital for
Children, Latvia
Track 2: Breaking Research Development in Stem Cell
Session 2-1: Stem Cell Genomics, Epigenetics & Systems Biology
Time: 15:30-17:40, October 12, 2013 (Saturday); Place: Room No. 618, 6th Floor, DICC
Chair Dr. Qiao Li, Assistant Professor/Principle Investigator, Faculty of Medicine, University of Ottawa,
Canada
15:30-15:35 Chair’s Introduction
15:35-16:00 Title: Transcriptional Regulation of Myogenic Differentiation
Dr. Qiao Li, Assistant Professor/Principle Investigator, Faculty of Medicine, University of Ottawa,
Canada
16:00-16:25 Title: Reprogramming towards Pluripotency Requires SMC1-Dependent Intrachromosomal
Looping
Dr. Jifan Hu, Professor, First Hospital, Jilin University, China; Director, Stem Cell and Cancer
Epigenetics Program, VA Palo Alto Health Care System, Stanford University Medical School,
USA
16:25-16:50 Title: The Biological Characteristics of Human Umbilical Cord Mesenchymal Stem Cells
Dr. Ma Lian, Vice President, Department of Pediatrics, Second Affiliated Hospital of Shantou
University Medical College, China
16:50-17:15 Title: Epigenetic Regulator Promotes Differentiation from Bone Marrow Derived-Mesenchymal
Stem Cells
Dr. Hye Joung Kim, Research Fellow, The Catholic University of Korea Seoul ST. Mary's
Hospital, South Korea
17:15-17:40 Title: Expression of RBMX after Spinal Cord Injury in Rats
Dr. Zhi-ming Cui, Head, Department of Spine Surgery, The Second Affiliated Hospital of
Nantong University, China
Session 2-2: Stem Cell Lineage, Derivation and Differentiation
Time: 08:30-10:05, October 13, 2013 (Sunday); Place: Room No. 618, 6th Floor, DICC
Chair Dr. Weidong Le, Professor of Neurology, Baylor College of Medicine, USA; Professor and
Principal Investigator, Institute of Health Sciences, SIBS, CAS, China
08:30-08:35 Chair’s Introduction
08:35-09:05 Title: Microrna Regulation of Stem Cells Differentiation into Dopamine Neurons
Dr. Weidong Le, Professor of Neurology, Baylor College of Medicine, USA; Professor and
Principal Investigator, Institute of Health Sciences, SIBS, CAS, China
09:05-09:35 Title: Enhanced Remyelinating and Immunomodulatory of Neural Stem Cells by Transduction of
Neurotrophin 3
Dr. Jingxian Yang, Director, Liaoning University of Traditional Chinese Medicine, China
09:35-10:05 Title: Characterization of Human Embryonic Stem Cells Differentiation to Bone Forming Cells
Dr. Amer Mahmood, Assistant Professor, King Khalid University Hospital King Saud University,
Saudi Arabia
10:05-10:30 Coffee Break
Session 2-3: Stem Cell Niches
Time: 10:30-12:15, October 13, 2013 (Sunday); Place: Room No. 618, 6th Floor, DICC
Chair Dr. Karl Tryggvason, Professor, Karolinska Institute, Sweden; Tanoto Professor, Duke-NUS
Graduate Medical School, Singapore
Co-Chair Dr. Gigi Ngar Chee Chiu, Assistant Professor, University of Singapore, Singapore
10:30-10:35 Chair’s Introduction
10:35-11:00 Title: Laminins - Extracellular Signaling Molecules in Differentiation and Phenotype Stability
Dr. Karl Tryggvason, Professor, Karolinska Institute, Sweden; Tanoto Professor, Duke-NUS
Graduate Medical School, Singapore
11:00-11:25 Title: Stem Cells, Stem Cell Niche and Organ Regeneration
Dr. Chunyi Li, Executive Director, State Key Laboratory for Molecular Biology of Special
Economic Animals, China
11:25-11:50 Title: Enhanced ex Vivo Expansion of Hematopoietic Stem/Progenitor Cells from Umbilical Cord
Blood by Functionalized Carbon Nanotubes
Dr. Gigi N. C. Chiu, Assistant Professor, National University of Singapore, Singapore
11:50-12:15 Title: Ubiquitination of Protease A20 Inhibited the Initiation of Caspase-8 in Brain Tumor Stem
Cells with TRAIL Resistance
Dr. Ling Qi, Director, Jilin Medical College, China
Session 2-4: Cancer Stem Cell (Part One)
Time: 08:30-12:10, October 13, 2013 (Sunday); Place: Room No. 621, 6th Floor, DICC
Chair Ms. Maria Cristina Tanzi, Director of Biomaterials Lab, Chemistry, Materials and Chemical
Engineering Department, Politecnico di Milano, Italy
Co-Chair Dr. Xiubao Chang, Associate Professor, Department of Biochemistry and Molecular Biology,
Mayo Clinic College of Medicine, USA
08:30-08:35 Chair’s Introduction
08:35-09:00 Title: PEG-Based Matrices for the in Vitro Study of Cancer Stem Cells under Non-Adhesive
Conditions
Ms. Maria Cristina Tanzi, Director of Biomaterials Lab, Chemistry, Materials and Chemical
Engineering Department, Politecnico di Milano, Italy
09:00-09:25 Title: Cancer Stemness in Mucinous Colon Cancer
Dr. Kiichiro Tsuchiya, Associate Professor, Department of Advanced Therapeutics for
Gastrointestinal Diseases, Tokyo Medical and Dental University, Japan
09:25-09:50 Title: Epigenetic and Genetic Involvements on CSCs (Cancer Stem Cells) Phenotype
Development: Possible Mechanism of Development and Potent Drugable Targets
Dr. Ioannis Papasotiriou, Director, Research Genetic Cancer Centre, Greece
09:50-10:15 Title: Immunotherapy Targeting Esophageal Cancer Stem Cells
Dr. Yi Zhang, Director and Professor, The Biotherapy Center and the Department of Oncology,
The First Affiliated Hospital, Zhengzhou University, China
10:15-10:30 Coffee Break
10:30-10:55 Title: Human Breast Cancer Stem Cells Have Significantly Higher Rate of Clathrin-Independent
and Caveolin-Independent Endocytosis than the Differentiated Breast Cancer Cells
Dr. Xiubao Chang, Associate Professor, Department of Biochemistry and Molecular Biology,
Mayo Clinic College of Medicine, USA
10:55-11:20 Title: Eradication of Gastrointestinal Cancer Stem Cells by Heavy Lon Radiotherapy
Dr. Sei Sai, Senior Researcher, Research Center for Charged Particle Therapy, National Institute
of Radiological Sciences, Japan
11:20-11:45 Title: Molecular Control of Neuroblastoma Differentiation
Dr. Hongjuan Cui, Professor, Southwest University, China
11:45-12:10 Title: Cytokines Microenvironment Deplete the Pool of Cancer Stem Cells to Inhibit Androgen
Independent Prostate Cancer
Dr. Wei Chen, Attending Doctor, Urology Department of Zhongshan Hospital, Fudan University,
China
Session 2-5: Induced Pluripotent Stem Cells (iPS) and Cellular Machinery, Cell Responses & Controlling
Time: 15:35-17:20, October 13, 2013 (Sunday); Place: Room No. 618, 6th Floor, DICC
Chair Dr. Vi Chu, R & D Manager, Merck-Millipore Corporation, USA
15:35-15:40 Chair’s Introduction
15:40-16:00 Title: PluriSTEM: Weekend & Holiday Free Culture of Pluripotent Human ES/iPS Cells
Dr. Vi Chu, R & D Manager, Merck-Millipore Corporation, USA
16:00-16:20 Title: CD133 Functions in Cell Survival
Dr. Zhong Li, Professor, The Second Military Medical University, China; Director, The 10th
Shanghai People’s Hospital, Tongji University, China
16:20-16:40 Title: ASCT Ips Generated from Blood Cells in a Natural Microenvironment for Clinical
Application
Mr. Hsou-Hsiung Pai, Consultant, Autologous Stem Cell Technology Pty. Ltd., Australia
16:40-17:00 Title: Hepatic Stem Cells; Heterogeneity and Control Mechanisms in Relation to Fibrosis
Dr. Nahed Baddour, Professor of Pathology, Alexandria Faculty of Medicine, Egypt
17:00-17:20 Title: Induced Pluripotent Stem Cells from ALS Patients
Dr. Min Deng, Assistant Researcher, Peking University Third Hospital, China
Session 2-6: Stem Cell & Tissue Development and Adult Stem Cell Research
Time: 08:30-10:55, October 14, 2013 (Monday); Place: Room No. 618, 6th Floor, DICC
Chair Dr. Rich Allsopp, Associate Professor, John A Burns School of Medicine, University of Hawaii,
USA
08:30-08:35 Chair’s Introduction
08:35-09:00 Title: The Gene Simplet is a Regulator of Canonical Wnt Signaling in Progenitor Cells of Growing
Appendages, Regenerating Bone and Developing Embryos
Dr. Christopher Antos, Group Leader, DFG-Center for Regenerative Therapies Dresden
(CRTD), Technisch Universitat Dresden, Germany
09:00-09:25 Title: Hypoxia Mediate Regulation of Telomerase in Stem Cells
Dr. Rich Allsopp, Associate Professor, John A Burns School of Medicine, University of Hawaii,
USA
09:25-09:50 Title: Notch Signaling Controls Germline Stem Cell Competitiveness for Niche Occupancy
Dr. Hweijan Hsu, Assistant Professor, Institute of Cellular and Organismic Biology, Academia
Sinica, Taiwan
09:50-10:15 Title: Spermatogonial Stem Cells: A Novel Source of Pluripotent Stem Cells for Regenerative
Medicine
Dr. Yingji Wu, Professor, Inner Mongolia University, China
10:15-10:30 Coffee Break
10:30-10:55 Title: The Role of Endogenous Stem Cells and Progenitor Cells in the Pathogenesis of
Myelosuppression, Pneumofibrosis and Diabetes
Dr. Evgenii G. Skurikhin, Chief of Research Team, Laboratory of Pathological Physiology and
Experimental Therapy, Institute of Pharmacology of RAMS SD, Russia
Track 3: Basic Sciences and Novel Technologies of Regenerative Medicin
Session 3-1: Cell Culture Technology, Bioreactor, Scaffolds, Biomaterials and Tissue Engineering
Construction
Time: 13:30-17:00, October 12, 2013 (Saturday); Place: Room No. 619, 6th Floor, DICC
Chair Dr. Michel Spina, Professor, University of Padova, Italy
Co-Chair Dr. Raúl Rosales Ibáñez, Research-Professor, Universidad Autonoma De San Luis Potosi,
Mexico
13:30-13:35 Chair’s Introduction
13:35-14:05 Title: Actual Biocompatibility Problems of Current Bioprosthetic Materials and Devices for Heart
Valve Replacement
Dr. Michel Spina, Professor, University of Padova, Italy
14:05-14:35 Title: Biodegradable and Electrically Conducting Polymers: Synthesis and Scaffold Design
Dr. Baolin Guo, Group Leader, Center for Biomedical Engineering and Regenerative Medicine,
Xi’an Jiaotong University, China
14:35-15:05 Title: Self Assembling Peptide Modified Demineralized Bone Matrix as a Scaffold for Enriching
Bone Marrow Promotes Bone Formation
Dr. Jianzhong Xu, Professor; Director, National and Local United Engineering laboratory of
Tissue Engineering, Southwest Hospital, The Third Military Medical University, China
15:05-15:30 Coffee Break
15:30-16:00 Title: Fifth Element of Tissue Engineering: In Situ Applications
Dr. Raul Rosales Ibanez, Research-Professor, Universidad Autonoma De San Luis Potosi,
Mexico
16:00-16:30 Title: Human Embryonic Stem Cells Established from Discarded Embryos and Passaged by
Chemical or Mechanical Methods for Bulk hESCs Expansion
Dr. Ying Liu, Associate Professor, Beijing Obstetrics and Gynecology Hospital, The Capital
University of Medical Science, China
16:30-17:00 Title: Quantenary Chiosan Salt Based Self Assemble Polyelectrolyte and Hybrid Gel as Soft
Contact Lens for Potential Biomedical Application
Dr. Xia Huang, Postdoctor, The university of Michigany, USA
Session 3-2: Cancer Stem Cell (Part Two)
Time: 13:30-15:15, October 13, 2013 (Sunday); Place: Room No. 621, 6th Floor, DICC
Chair Dr. Shuen-Kuei Liao, Chief Scientific Officer, Vectorite Biomedica Inc., Taiwan; Visiting
Professor, Taipei Medical University, Taiwan
13:30-13:35 Chair’s Introduction
13:35-14:00 Title: Targeting Cancer Stem Cells with Withaffirin a Via Inhibition of Induction of
CXCR4-Positive Metastatic Cancer Stem Cells and STAT3 Phosphorylation
Dr. Shuen-Kuei Liao, Chief Scientific Officer, Vectorite Biomedica Inc., Taiwan; Visiting
Professor, Taipei Medical University, Taiwan
14:00-14:25 Title: Applications of Theoretical Computer Science in Cancer Stem Cell Research
Mr. Andrew Ninh, CEO, President, Co-Founder, ScheiNinh LLC, USA
14:25-14:50 Title: The Speculation and Discussion of the Application Management ofRegeneration Medicine
and Cell Therapy Technology in China
Hu Bo, Broad Chairman, Ciming Medical Group-Oasis Wellness Club Life Medical Center;
Deputy Director, Secretary-General, Committee for Medical Technology Administration of the
Chinese Hospital Association (MTA), China
14:50-15:15 Title: Targeting PI3K in Breast Cancer
Dr. Pixu Liu, Professor, Institute of Cancer Stem Cell, Dalian Medical University, China
Session 3-3: Growth Factors and Morphogens in Regenerative Medicine
Time: 15:30-17:15, October 13, 2013 (Sunday); Place: Room No. 621, 6th Floor, DICC
Chair Dr. Richard G. LeBaron, Associate Professor, University of Texas at San Antonio, USA
15:30-15:35 Chair’s Introduction
15:35-16:00 Title: Extracellular Matrix, Growth Factors and Morphogens: Promise of Tissue Regeneration
Accentuation
Dr. Richard G. LeBaron, Associate Professor, University of Texas at San Antonio, USA
16:00-16:25 Title: Molecular Pathways in VEGF-Induced Angiogenesis and Vascular Regeneration
Dr. Zheng Gen Jin, Associate Professor, University of Rochester School of Medicine, USA
16:25-16:50 Title: Neuropeptide SP Activates WNT Signal Transduction Pathway and Enhances the
Proliferation of Bone Marrow Stromal Stem Cells
Dr. Dan Jin, Professor; Chief Physician, Nangfang Hospitol, China
16:50-17:15 Title: Role of VEGF in Bone Formation
Dr. Yanqi Yang, Assistant Professor, The University of Hong Kong, Hong Kong, China
Session 3-4: Immunity Research and Regeneration Medicine
Time: 10:55-12:00, October 14, 2013 (Monday); Place: Room No. 618, 6th Floor, DICC
Chair Dr. Hans-Dieter Volk, Full Professor of Immunology, Director, Institute of Medical Immunology &
Berlin-Brandenburg Center for Regenerative Therapies (BCRT), Charité Universitätsmedizin
Berlin, Germany
10:55-11:00 Chair’s Introduction
11:00-11:30 Title: The Negative Co-Stimulatory Molecules Expressed on Mesenchymal Stem Cells and
Mediate Their Immuno-Modulating Effect on T Cells
Dr. Qun Xue, Chief Physician, Neurology Department of the First Affiliated Hospital of Soochow
University, China
11:30-12:00 Title: Adoptive T Reg/Eff Cell Therapy to Regenerate‖ Protective Immunity after Transplantation
Dr. Petra Reinke, Medical Director; Head of the ―Kidney Transplant Outpatient Clinic‖; Head of
the GMP-Facility, Charité-Universitätsmedizin Berlin, Charité Campus Virchow-Klinikum,
Germany
Session 3-5: Novel Technology in Regeneration Medicine: Nanotechnology, Imaging, Modelling and
Monitoring
Time: 08:30-10:15, October 14, 2013 (Monday); Place: Room No. 619, 6th Floor, DICC
Chair Dr. George Altankov, ICREA Research Professor, Institute for Bioengineering of Catalonia,
Spain
08:30-08:35 Chair’s Introduction
08:35-09:00 Title: Fluorescent Nanodiamonds Enable in vivo Tracking of Prospectively Isolated Lung Stem
Cells
Dr. John Yu, Distinguished Research Fellow, Institute of Cellular & Organismic Biology and the
Genomics Research Center, Academia Sinica, Taiwan
09:00-09:25 Title: Nanofibres Design for Guided Cellular Behaviour
Dr. George Altankov, ICREA Research Professor, Institute for Bioengineering of Catalonia,
Spain
09:25-09:50 Title: High Speed, High Content Multi-Spectral Cellular Imaging in Flow Cytometry, Novel
Technology for Research Strategies in Regenerative & Stem Cell Research
Mr. George McBride, Senior Regional Field Applications Manager, Cellular Analysis–Asia,
Merck Millipore Bioscience Division of Merck KGaA, Singapore
09:50-10:15 Title: Nanoscale Architectures for Controlling Cellular Mechanoresponse
Dr. Shalom J. Wind, Senior Research Scientist/Professor, Columbia University, USA
10:15-10:30 Coffee Break
Track 4: Clinical Translations of Regenerative Therapy
Session 4-1: Angiogenesis and Cardiac Tissue Repair
Time: 13:30-17:10, October 12, 2013 (Saturday); Place: Room No. 620, 6th Floor, DICC
Chair Dr. Philippe Henon, Director, Research Institute of Hematology and Transplantation, Universite
de Haute Alsace, France
Co-Chair Dr. Austin Guo, Assistant Professor, New York Medical College, USA
13:30-13:35 Chair’s Introduction
13:35-14:00 Title: Discovery of Novel Molecules for in situ Cardiac Regeneration
Dr. Qingdong Wang, Leader of Regenerative Medicine Innovation Team, AstraZeneca R & D
Mölndal, Sweden
14:00-14:25 Title: Academic to Industry Translation in CD34+ Cell Therapy for Treatment of Acute Myocardial
Infarct (AMI): A Long Obstacle Race
Dr. Philippe Henon, Director, Research Institute of Hematology and Transplantation, Universite
de Haute Alsace, France
14:25-14:50 Title: Cardiac Stem/Progenitor Cells: Cardiac Side Population Cells
Dr. Simon X. Liang, Head and Professor, Department of Biochemistry and Molecular Biology,
Liaoning Medical University, China
14:50-15:15 Title: Application of Stem Cells and Reprogrammed Cardiomyocytes in Myocardial Regeneration
Dr. Xiaowen Bai, Assistant Professor, Medical College of Wisconsin, USA
15:15-15:30 Coffee Break
15:30-15:55 Title: 20-HETE Regulates Angiogenic Functions of Human Endothelial Progenitor Cells
Dr. Austin Guo, Assistant Professor, New York Medical College, USA
15:55-16:20 Title: The Tandem Telocytes & Stem Cells vs. the Stem-Cell Dogma in Cardiac Repair
Dr. Lawrence M. Popescu, Professor of Cellular and Molecular Medicine, University of Medicine
and Pharmacy, Romania; Head, the National Institute of Pathology, Romania
16:20-16:45 Title: NADPH Oxidase Derived ROS Signalling in Angiogenesis
Dr. Hitesh M Peshavariya, Research Fellow, Centre for Eye Research Australia, University of
Melbourne, Australia
16:45-17:10 Panel Discussion
Session 4-2: Neural Degenerative Diseases, Stroke and CNS Repairing
Time: 13:30-17:10, October 12, 2013 (Saturday); Place: Room No. 621, 6th Floor, DICC
Chair Dr. Sha Mi, Distinguished Investigator in Discovery Neurobiology, Biogen Idec, USA
Co-Chair Dr. Alex Kharazi, Chief Technology Officer, Stemedica Cell Technologies, USA
13:30-13:35 Chair’s Introduction
13:35-14:00 Title: Blocking the LINGO-1 Pathway as a Novel Therapeutic Approach for CNS Repair
Dr. Sha Mi, Distinguished Investigator in Discovery Neurobiology, Biogen Idec, USA
14:00-14:25 Title: Neural Signal Regeneration and Motor Function Rebuilding of Paralyzed Limbs. Based on
Principles of Communication and Functional Electrical Stimulation
Dr. Zhigong Wang, Professor, Institute of RF- & OE-ICs Southeast University, China
14:25-14:50 Title: Promote Axon Regeneration and Functional Recovery after CNS Injury
Dr. Shuxin Li, Associate Professor, Shriners Hospitals Pediatric Research Center, Temple
University School of Medicine, USA
14:50-15:15 Title: Involuntary Muscle Spasm Expressed as Motor Evoked Potential after Olfactory Mucosa
Autograft in Patients with Chronic Spinal Cord Injury and Complete Paraplegia
Dr. Koichi Iwatsuki, Associate Professor, Osaka University Medical School, Japan
15:15-15:30 Coffee Break
15:30-15:55 Title: Human Mesenchymal Stem Cells for the Treatment of Stroke
Dr. Alex Kharazi, Chief Technology Officer, Stemedica Cell Technologies, USA
15:55-16:20 Title: Efficacy of Stem Cell Therapy in Cerebral Palsy
Dr. Anant Bagul, Director, Chaitanya Hospital & Stem Cell Center, India
16:20-16:45 Title: Bio Modulation of Autologus Bone Marrow –A New Treatment Strategy in Chronic Spinal
Cord Injury.
Dr. PS John, Head, Department of Regenerative Medicine, St. Thomas Hospital, India
16:45-17:10 Title: Cell Therapy for Perinatal Cerebral Injury — From Basic Research to Clinical Trial
Dr. Zuo Luan, Chief Physician, Department of Pediatrics, Navy General Hospital, China
Session 4-3: Repair and Regeneration of Oral and Craniofacial Tissues
Time: 08:30-12:00, October 13, 2013 (Sunday); Place: Room No. 619, 6th Floor, DICC
Chair Dr. Wolf-Dieter Grimm, Professor of Periodontology, University of Witten/Herdecke, Germany
Co-Chair Dr. Shuying Yang, Assistant Professor, The State University of New York, USA
08:30-08:35 Chair’s Introduction
08:35-09:05 Title: Use of Stem-Cell Induced Allogenic Bonerings® for Pre-Implantological Vertical
Augmentations of Alveolar Bone Defects in Humans-A Clinical Controlled Study
Dr. Wolf-Dieter Grimm, Professor of Periodontology, University of Witten/Herdecke, Germany
09:05-09:35 Title: Dentin Regeneration on Exposed Dental Pulp by Phosphophoryn-Derived RGD Peptide
Dr. Takashi Saito, Professor, Health Sciences University of Hokkaido, Japan
09:35-10:05 Title: Estrogen-mediated Differentiation of Adult Dental Stem Cells
Dr. Jinhua Yu, Associate Director, Institute of Stomatology, Nanjing Medical University, China
10:05-10:30 Coffee Break
10:30-11:00 Title: Gene and Stem Cell Based Vascularized Bone Regeneration for Critical-sized Bone Defect
Dr. Shuying Yang, Assistant Professor, The State University of New York, USA
11:00-11:30 Title: Bio Engineering Bone Parts. Application in Dentistry and in Periodontology
Dr. S. Sankaranarayanan, Director, Mothercell Regenerative Centre, India
11:30-12:00 Title: Enhancing Bone Vascularization towards Regeneration after Cancer Ablation
Dr. Ahmad Eweida, Assistant Lecturer, Alexandria University, Egypt
Session 4-4: Digestive Respiratory and Urologic Tissues and Organ Regeneration
Time: 08:30-10:30, October 13, 2013 (Sunday); Place: Room No. 620, 6th Floor, DICC
Chair Dr. Very Coulic, Professor and Researcher, CHU Brugmann, ULB, Experimental Medicine
Laboratory, Belgium
Co-Chair Dr. Ena Ray Banerjee, Associate Professor, University of Calcutta, India
08:30-08:35 Chair’s Introduction
08:35-08:55 Title: Fetal Organ Transplantation as a Step in Regenerative Medicine
Dr. Very Coulic, Professor and Researcher, CHU Brugmann, ULB, Experimental Medicine
Laboratory, Belgium
08:55-09:15 Title: Novel Regenerative Treatment of Male Stress Urinary Incontinence by Periurethral
Injection of Autologous Adipose-Derived Regenerative Cells: 1-Year Outcomes in 11 Patients
Dr. Tokunori Yamamoto, Associate Professor, Nagoya University, Japan
09:15-09:35 Title: Kidney Regeneration by Non-Platelet RNA-Containing Particle-Derived Cells
Dr. Wuyi Kong, Director, Beijing Khasar Medical Technology Co., China
09:35-09:55 Title: Human Pluripotent Stem Cell-Derived Mesenchymal Stem Cells Prevent Allergic Airway
Inflammation
Dr. Qingling Fu, Associate Professor, Otorhinolaryngology Hospital, The First Affiliated Hospital,
Sun Yat-sen University, China
09:55-10:15 Title: Looking for the Elusive Lung Stem Cell Niche
Dr. Ena Ray Banerjee, Associate Professor, University of Calcutta, India
10:15-10:30 Coffee Break
Session 4-5: Bone and Cartilage Tissue Repairing
Time: 10:30-12:15, October 13, 2013 (Sunday); Place: Room No. 620, 6th Floor, DICC
Chair Dr. Kwan Hee Lee, Chief Medical Officer, TissueGene, Inc., USA
10:30-10:35 Chair’s Introduction
10:35-11:00 Keynote Speech:
Title: Clinical Applications of Mesenchymal Stem Cells in the Treatment of Fracture Non-Union,
Bone Defects and Osteonecrosis
Dr. Stefano Zanasi, Professor, University of Florence, Italy
11:00-11:25 Title: Clinical Development of Cell and Gene Therapy for Cartilage Regeneration in Severe
Osteoarthritis Patients
Dr. Kwan Hee Lee, Chief Medical Officer, TissueGene, Inc., USA
11:25-11:50 Title: Effect of G-CSF on Neovascularization and Osteogenesis in Aged Osteoporotic Bone
Dr. Liwu Zheng, Clinical Assistant Professor, The University of Hong Kong, Hong Kong, China
11:50-12:15 Title: Tissue Engineering Cartilage Repair Articular Cartilage Injury-----From Basic to Clinicall
Dr. Quanyi Guo, Professor, Institute of Orthopedic Research, General Hospital of the People's
Liberation Army, China
Session 4-6: Musculoskeletal Tissue Regeneration and Wounded Skin Repair
Time: 13:30-15:15, October 13, 2013 (Sunday); Place: Room No. 619, 6th Floor, DICC
Chair Dr. Redha Taiar, Professor, University of Reims Champaign, France
Co-Chair Dr. Marco Brotto, Endowed Professor of Nursing & Medicine, Director of the Muscle Biology
Research Group, University of Missouri-Kansas City, USA
13:30-13:35 Chair’s Introduction
13:35-14:00 Title: Simulation and Modelization of the Human Body: New Perspectives
Dr. Redha Taiar, Professor, University of Reims Champaign, France
14:00-14:25 Title: Targeting the DNA Damage Response Pathways in the Repair of Acute Thermal and
Ultraviolet Light Injury
Dr. Madalene C. Y. Heng, Professor, UCLA School of Medicine/Dermatology, USA
14:25-14:50 Title: Bone-Muscle Crosstalk: New Insights into Myogenesis and Muscle Function-New Ideas for
Muscle Regeneration?
Dr. Marco Brotto, Endowed Professor of Nursing & Medicine, Director of the Muscle Biology
Research Group, University of Missouri-Kansas City, USA
14:50-15:15 Title: Regulation Mechanism of Wnt Signaling Pathway Involved in the Differentiation of Hair
Follicle Stem Cells Induced by Lithium Chloride
Dr. Bin Yang, Professor, Plastic Surgery Hospital (Institute), Chinese Academy of Medical
Sciences, China
15:15-15:30 Coffee Break
Session 4-7: Anti-aging & Cosmetology and Regenerative Medicine
Time: 15:30-17:15, October 13, 2013 (Sunday); Place: Room No. 619, 6th Floor, DICC
Chair Dr. Qizhi Chen, Reader, Monash University, Australia
15:30-15:35 Chair’s Introduction
15:35-15:55 Title: Delivering Stem Cells to Treat Diseased Soft Organs using Elastomeric Biomaterials
Dr. Qizhi Chen, Reader, Monash University, Australia
15:55-16:15 Title: Restorative Technology in Hair Transplant: Case of ACell Use at myWHTC
Dr. Patrick Mwamba, Medical Director, World Hair Transplant Center, Belgium
16:15-16:35 Title: Osteoplastic Surgery of the Face As a Regenerative and Restorative Surgical Procedure in
Aesthetic and Plastic-Reconstructive Surgery
Dr. Kurt Vinzenz, Director of Oral and Maxillofacial Surgery, Evangelisches Krankenhaus
Wien, Vienna University, Austria
16:35-16:55 Title: Cellular and Molecular Regulation of New Insulin-Producing Cells from Duct Progenitors
during Pancreas Regeneration
Dr. Wan-Chun Li, Assistant Professor, Department of Dentistry & Institute of Oral Biology,
National Yang-Ming University, Taiwan
16:55-17:15 Title: The Role of Regenerative Medicine in Rejuvenation
Dr. Yuan-Sung Kuo, Clinical Assistant Professor, College of Medicine, National Taiwan
University, Taiwan
Session 4-8: Stem Cell Therapy for Disease and Artificial Organ
Time: 08:30-12:10, October 14, 2013 (Monday); Place: Room No. 620, 6th Floor, DICC
Chair Dr. Alain Chapel, Principal Investigator, Institute of Radioprotection and Nuclear Safety (IRSN),
France
08:30-08:35 Chair’s Introduction
08:35-09:00 Title: Human Stem Cell Therapy for the Treatment of Radiation - Induced Normal Tissue
Damage
Dr. Alain Chapel, Principal Investigator, Institute of Radioprotection and Nuclear Safety (IRSN),
France
09:00-09:25 Title: Nonhuman Primate Disease Model Applications for Stem Cell-based Efficacy Evaluation
Dr. Rosario M. Perez, Director, Maccine Pte Ltd., Singapore
09:25-09:50 Title: Hepatic Regenerative Potential of Mouse Bone Marrow very Small Embryonic-Like Stem
Cells
Dr. Gangming Zou, Professor, Shanghai Jiao Tong University, China
09:50-10:15 Title: Fetal Progenitor Cells and Cord Blood Stem Cells in Complex Treatment of Chronic Limb
Ischemia, Pancreonecrosis and Chronic Wounds: Clinical Trials Results
Dr. Oleksandr Kukharchuk, Research Director, EmProCell Clinical Research Pvt. Ltd., India
10:15-10:30 Coffee Break
10:30-10:55 Title: Regenerative Medicine in Orthopedics
Dr. V. R. Ravi, Director, Mothercell Regenerative Centre, India
10:55-11:20 Title: BMSC Transplantation Treating Acute Liver Failure in Rat Model
Dr. Yue-Xin Zhang, Professor, First Affiliated Hospital, Xinjiang Medical University, China
11:20-11:45 Title: Donor Chimera Model for Tolerance Induction in Transplantation
Dr. Monireh Dashty, Medical Doctor and Biologist, University of Groningen, The Netherlands
11:45-12:10 Panel Discussion
Track 5: Young Scientist Research
Session 5-1: Young Scientist Research
Time: 10:55-11:50, October 14, 2013 (Monday); Place: Room No. 619, 6th Floor, DICC
Chair Dr. Hans-Peter Deigner, Professor, Furtwangen University, Germany
10:30-10:35 Chair’s Introduction
10:35-11:00 Title: Evaluation of Glioma-targeting Capacity of Human Umbilical Cord Derived Mesenchymal
Stem Cells in vivo
Dr. Cungang Fan, Attending Neurosurgeon; Principle Investigator of Glioma Specialty; Head of
Bio-Bank in the Neurosurgical Department, Peking University People’s Hospital, China
11:00-11:25 Title: Novel Aspect on Regulatory T Cells-A New Cellular Source for Cell Therapy
Dr. Hong Lei, Ph.D. Candidate, Berlin-Brandenburg Center for Regenerative Therapies, Charite
University Medicine Berlin, Germany
11:25-11:50 Title: Characterisation of 3D Organotypic Cultures of H400 and Primary Rat Keratinocytes
Dr. Erum Khan, School of Dentistry, University of Birmingham, UK
Chinese Scientist Forum (Language: Mandarine)
Chinese Scientist Forum (Language: Mandarine)
Time: 13:30-17:10, October 13, 2013 (Sunday); Place: Room No. 620, 6th Floor, DICC
Chair Dr. Chunmeng Jiang, Director, Gastroenterology Department of the Second Affiliated Hospital
of Dalian Medical University, China
13:30-13:35 Chair’s Introduction
13:35-13:55 Title: Clinical Research of Autologous Transplantation of Bone Marrow Stem Cells on
Decompensate Cirrhosis Patients
Dr. Chunmeng Jiang, Director, Gastroenterology Department of the Second Affiliated Hospital
of Dalian Medical University, China
13:55-14:15 Title: The Cilinical Therapeutic Effects of Human Umbilical Cord Mesenchymal Stem Cell
Transplantation in Treatment of End Stage Liver Disease
Weizheng Zeng, Professor and Chief Physician, Chengdu Military General Hospital, China
14:15-14:35 Title: A GATA-4 Target, EGF, Regulates Cell Proliferation and Differentiation by Modulating the
Cell Cycle Regulatory Protein Cyclin D1
Mingxi Zang, Associate Professor, Zhenzhou University, China
14:35-14:55 Title: Preliminary Protection of Oleanolic Acid Attenuates Neural Stem Cells Differentiation into
Astrocytes through JAK/STAT Signaling Pathway
Dr. Yulian Zhang, Subdecanal and Archiater, The Second Affiliated Hospital of Tianjin Medical
University, China
14:55-15:15 Title: Shear Stress-Induced Activation of Tie2-Dependent Signaling Pathway Enhances in Vivo
Reendothelialization Capacity of Human Endothelial Progenitor Cells
Dr. Zhen Yang, Associate Professor, The First Affiliated Hospital of Sun Yat-Sen University,
China
15:15-15:30 Coffee Break
15:30-15:50 Title: Autologous Peripheral Blood Stem Cells Transplantation for the Treatment of Diabetic
Vascular Disorder in Lower Extremities
Hua Li, Attending Doctor, The Second Hospital of Xiamen, China
15:50-16:10 Title: Human Mesenchymal Stem Cells and Tumor Growth
Dr. Juan Liu, Resident Physician, Provincial Hospital Affiliated to Shandong University, China
16:10-16:30 Title: Safety and Efficacy Evaluation of a Human Acellular Nerve Graft as a Digital Nerve
Scaffold: A Prospecti Ve, Multicentre Controlled Clinical Trial
Dr. Bo He, Attending Physician, The First Affiliated Hospital, Sun Yat-sen University, China
16:30-16:50 Title: Adipose-Derived Stem Cells Improved Mouse Ovaryfunction after Chemotherapy-Induced
Ovary Failure
Dr. Min Sun, Ph.D. Candidate, Fourth Military Medical University, China
16:50-17:10 Title: Generation of Knockout/inMouse Models Using Novel Custom Endonuclease Technologies
Dr. Steve X. Yu, Director of Technology, Cyagen Biosciences, Inc., USA/China