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Scientific Writing in Medical Sciences
Dr L. Ghalichi
Department of Epidemiology & Biostatistics
School of public health
Tehran University of Medical Sciences
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Research OutputThree different research output
are expected from research proposals:1- Paper2- Patent3- Change
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مقايسه فراواني مقاالت و ارجاعات صورت گرفته به مقاالت منتشرشده دانشگاه علوم پزشکي تهران و دانشگاه تهران با دانشگاه های رتبه يکصدم
THS-QS تايمز 2009در رتبه بندی سال Scopusو دويستم دنيا در مجموعه
رتبه دانشگا
هنام دانشگاه کشور
تعداد 5مقاالت
ساله در Scopus
تعداد ارجاعات
به 5مقاالت ساله اخير Scopus
تعداد اعضاي هيئت علمي
نسبت ارجاع
به عضو هيئت علمي
نسبت ارجاع
به مقاله
100
Riceدانشگاه آمريکا 6254 66343 772 85/9 10/61
200
دانشگاه Twente
هلند 6193 37403 1000 37/4 6/04
201
دانشگاه اندونزی
اندونزی
549 2093 4321 0/48 3/81
368
دانشگاه علوم پزشکي
تهران و دانشگاه
تهران
ايران 11359 31030 3243 9/6 2/37
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Why “Scientific Writing”?
The purpose of scientific writing is to convey ideas and facts about scientific work.
Scientists understand and criticize each other's work through their articles.
Thus, scientific writing should be intelligible to readers at the first reading.
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Why Publish?
Knowledge contributionsEnsures scientific rigorAllows feedback (improves work)Promotes career
◦ Document productivity◦ Document impact on field/reputation◦ Advertises your lab for future trainees
Improves chances of fundingFulfills an obligation (public
monies)
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Evaluating an Academic Person though his/her CV Papers
Number of papers Rate of publication Quality of journals Position in list of authors Focus
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The Art of Scientific Writing
Publish or Perish!
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Steps in Scientific Writing
Design wellDecide politicsChoose journalRead instructions to authors/papersSet frameworkPrepare draftsDistributePolishSubmit
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START
STUDIES/EXPERIMENTS
WRITE ANDSUBMIT
REWRITE ANDRESUBMIT
WAIT
PUBLISHED!
4-24 months
2-4 months
2-4 months
2-4 months
2-4 months
14-44 Months!PROTOCOL/IRB 2-4 months
BEST GUESS
What is the gestational period for a clinical science publication?
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Two Types of StudiesPrimary StudySecondary Study
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Primary studies
Experiments Clinical trialsSurveys
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Reviews (Overviews) Narrative reviews Systematic reviews & Meta-
analyses Guidelines Decision analyses Economic analyses Review Article
Secondary studies
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Types of Medical articles
Original ArticleReview ArticleCase ReportsEditorial Short Communication (short
papers)Letter to EditorPersonal Views
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LetterStick to the pointState the problem, issue or
hypothesisGive the contextOutline your comment, solution,
viewpointGive a strong conclusionNote limitations
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Editorial Write for your readership
(broad?)Be controversial and thought
provokingBeing subtle is often more
powerful
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Short communicationIncreasingly commonConcise introductionPresent data and discuss it
shortlyOnly a few tables or figuresNumber of words limitations
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Is your paper a paper, a brief or a research letter?
Easier to get letters & briefs accepted .
They make you indexed easier !Decide whether you should
submit it as a brief or letter firstly.
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Case ReportsMedical history of a single patient in a
story form.Lots of information given which may not
be seen in a trial or a survey.Often written and published fast
compared to studiese.g. Thalidomide
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The Hierarchy of Evidence
1. Systematic reviews & meta-analyses
2. Randomised controlled trials
3. Cohort studies
4. Case-control studies
5. Cross sectional surveys
6. Case reports
7. Expert opinion
8. Anecdotal
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Hierarchy of studies
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The traditional IMRaD
◦Introduction◦Methods◦Results◦Discussion
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The Basic Structure of an ArticleTITLE(S)Summary (Structured Abstract)(I) Introduction (What Question was
asked?)(M)Methods (How was it Studied?)(R)Results (What was Found?)(A)Analysis (How data was
analysed?)(D)Discussion (What Do the Findings
Mean?)AcknowledgementsReferences
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Main Components of an ArticleIntroduction: Why did
you start?Methods: What did you
do?Results: What did you
find?Discussion: What does it all
mean?
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25
Abstract Introduction Methods Results Discussion Conclusions
“Bowtie” Model For a Scientific Paper
Broad Ideas Specific Ideas Broad Ideas
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A full paper may contain:
Title Authors and Affiliation Abstract Introduction Methods Results Discussion Acknowledgments (optional)
References
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Initial steps1-Understand the type of manuscript you are
writing. 2-Re-evaluate your project. 3-Plan the sections and subsections you need.4-Match your content to your readers’
knowledge. 5-Keep information specific rather than
general. 6-Write in plain language. Keep your sentences
short. 7-Use tables, diagrams, flowcharts and graphs.
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Politics first!
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Order of writing?
1. Results2. Methods3. Introduction4. Discussion5. Abstract6. References
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More reading
Hall GM, ed. How to write a paper. London: BMJ Publishing
Group.
Advanced Writing, Floresita V.Bustamante, SAMT
Essentials of Writing Biomedical Research Papers, Zeiger
Scientific Writing Easy when you know how. Peat J. BMJ
Publishing Group. 2002.
The Vancouver Group. Uniform requirements for
manuscripts submitted to biomedial journals.
www.icmje.org
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How to Write Introduction Section?
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Introduction
Before you begin, answer the basic questions:
◦What do I have to say?◦Is it worth saying?◦What is the right format?◦Who is the audience?◦What is the right journal?
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Introduction
General, concise description of problem◦background to the work◦previous research
Where that work is deficient◦how your research will be better
State the hypothesisAbout 3 to 4 paragraphs
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Paragraph1:What we know
Paragraph2:What we don’t know
Paragraph3:Why we did this study
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Introduction
1. Existing state of knowledge2. Gaps in knowledge which research
will fill.3. State what you Intend to do & the
purpose of article4. Give pertinent references5. Summarize the rationale for study
or observation6. Define specialized terms or
abbreviations you want to use
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Inverted pyramidThe structure should funnel down
from a broad perspective to a specific aim
Oxidative stress plays an important role in....
When LDL particles are oxidized ...Antioxidants are important...
...Paraoxonase...
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Don’t make it a review articleDon not include methods, results
and discussionDon’t put down every all previous
studies & their data gapsDon’t explain pathophysiology
irrelevant to your study
Introduction
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IntroductionTell why you have undertaken the
studyClarify what your work addsFollow the best adviceKeep it shortMake sure you are aware of earlier
studiesTell about importance of your studyDon’t baffle your readersGive the study designThink about using journalistic tricks
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Introduction
To write an effective introduction you must:
◦Know your audience◦Keep it short◦Tell readers why you have done the study◦Explain why it is important◦Convince readers that it is better than
others◦Try to hook them!