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2007-2008AP Biology
Tour of the Cell 1
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AP Biology
Prokaryotebacteria cellsTypes of cells
Eukaryoteanimal cells
- no organelles
- organelles
Eukaryoteplant cells
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AP Biology
Why organelles? Specialized structures
specialized functions cilia or flagella for locomotion
Containers partition cell into compartments create different local environments
separate pH, or concentration of materials distinct & incompatible functions
lysosome & its digestive enzymes Membranes as sites for chemical reactions
unique combinations of lipids & proteins embedded enzymes & reaction centers
chloroplasts & mitochondria
mitochondria
chloroplast
Golgi
ER
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AP Biology
Cells gotta work to live! What jobs do cells have to do?
make proteins proteins control every
cell function make energy
for daily life for growth
make more cells growth repair renewal
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2007-2008AP Biology
Building Proteins
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AP Biology
Proteins do all the work!
cellsDNA
proteins
organismRepeat after me…
Proteins do all the work!
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AP Biology
Cells functions Building proteins
read DNA instructions build proteins process proteins
folding modifying
removing amino acids adding other molecules
e.g, making glycoproteinsfor cell membrane
address & transport proteins
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AP Biology
Building Proteins Organelles involved
nucleus ribosomes endoplasmic reticulum
(ER) Golgi apparatus vesicles
nucleus ribosome ER Golgiapparatus vesicles
The Protein Assembly Line
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AP Biology
nuclearpores
nuclearpore
nuclear envelopenucleolus
histone protein
chromosome
DNA
Function protects DNA
Structure nuclear envelope
double membrane membrane fused in spots to create pores
allows large macromolecules to pass through
Nucleus
What kind of molecules need to
pass through?
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AP Biology
DNA
NucleusmRNA
nuclearmembrane
smallribosomal
subunit
largeribosomal
subunit
cytoplasm
mRNA
nuclear pore
production of mRNAfrom DNA in nucleus
mRNA travels fromnucleus to ribosomein cytoplasm throughnuclear pore
1
2
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AP Biology
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AP Biology
Nucleolus Function
ribosome production build ribosome subunits from rRNA & proteins exit through nuclear pores to cytoplasm &
combine to form functional ribosomes
smallsubunit
large subunit
ribosome
rRNA &proteins
nucleolus
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AP Biology
smallsubunit
largesubunitRibosomes
Function protein production
Structure rRNA & protein 2 subunits combine 0.08µm
RibosomesRough
ER
SmoothER
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AP Biology membrane proteins
Types of Ribosomes Free ribosomes
suspended in cytosol synthesize proteins that
function in cytosol Bound ribosomes
attached to endoplasmicreticulum
synthesize proteinsfor export orfor membranes
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AP Biology
Endoplasmic Reticulum Function
processes proteins manufactures membranes synthesis & hydrolysis of many compounds
Structure membrane connected to nuclear envelope &
extends throughout cell
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AP Biology
Types of ER
rough smooth
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AP Biology
Smooth ER function Membrane production Many metabolic processes
synthesis synthesize lipids
oils, phospholipids, steroids & sex hormones
hydrolysis hydrolyze glycogen into glucose
in liver detoxify drugs & poisons
in liver ex. alcohol & barbiturates
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AP Biology
Membrane Factory Build new
membrane synthesize
phospholipids builds membranes
ER membraneexpands bud off & transfer
to other parts ofcell that needmembranes
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AP Biology
Rough ER function Produce proteins for export out of cell
protein secreting cells packaged into transport vesicles for export
Which cellshave lot of rough ER?
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AP Biology
Synthesizing proteins
cytoplasm
cisternalspace
mRNA
ribosome
membrane ofendoplasmic reticulum
polypeptide
signalsequence
ribosome
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AP Biology
Golgi Apparatus
Which cellshave lots of Golgi?
transport vesicles
secretoryvesicles
Function finishes, sorts, tags & ships cell products
like “UPS shipping department” ships products in vesicles
membrane sacs “UPS trucks”
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AP Biology
Golgi Apparatus
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AP Biology
Vesicle transport
vesiclebuddingfrom roughER
fusionof vesiclewith Golgiapparatus
migratingtransportvesicle
protein
ribosome
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Regents Biology
DNA
RNA
ribosomes
endoplasmicreticulum
vesicle
Golgi apparatus
vesicle
proteinon its way!
protein finishedprotein
Making Proteins
TO:
TO:
TO:
TO:
nucleus
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AP Biology
proteins
transportvesicle Golgi
apparatus
vesicle
smooth ER
rough ER
nuclear porenucleus
ribosome
cellmembrane protein secreted
cytoplasm
Making proteinsPutting it together…
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AP Biology
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AP Biology
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2007-2008AP Biology
Any Questions!!