Transposons

First discovered in plants

Transposition to a new site

Transposons

*Three classes of transposons

Class I : Retrotransposons

Class II: Transposons

Class III: Miniature Inverted-repeat Transposable Elements

*Transposons can be autonomous or nonautonomous

Transposons

Transposase

Cut and paste mechanism of transposition (nonreplicative)

Transposons

Transposons

Mechanism of replicative transposition

Transposons

Mechanism of replicative transposition

Transposons

Mechanism of retrotransposon integration

Transposons

Littering the human genome

Transposons

Böhne, et al. 2008