Tre1 GPCR initiates germ cell transepithelial migration by regulating E-cadherin
Prabhat S. Kunwar, Hiroko Sano, Andrew D. Renault, Vitor Barbosa, Naoyuki Fuse, and Ruth Lehmann
J. Cell Biol.Volume 0(2008):1-f-12
September 2, 2008
© 2008 Kunwar et.al.
Figure 1. Live imaging of germ cell migration through the midgut in wild-type and tre1 mutant embryos
Kunwar et al. J. Cell Biol. 2008:0:1-f-12
© 2008 Kunwar et.al.
Figure 2. Gβ13f and Gγ1 act downstream of tre1 in transepithelial migration
Kunwar et al. J. Cell Biol. 2008:0:1-f-12
© 2008 Kunwar et.al.
Figure 3. Tre1 regulates germ cell polarization and G protein localization
Kunwar et al. J. Cell Biol. 2008:0:1-f-12
© 2008 Kunwar et.al.
Figure 4. DE-cadherin is required for germ cell–germ cell adhesion
Kunwar et al. J. Cell Biol. 2008:0:1-f-12
© 2008 Kunwar et.al.
Figure 5. tre1 regulates DE-cadherin localization in the tail of germ cells
Kunwar et al. J. Cell Biol. 2008:0:1-f-12
© 2008 Kunwar et.al.
Figure 6. Reduction of DE-cadherin function or adhesion between germ cells does not rescue the tre1 phenotype
Kunwar et al. J. Cell Biol. 2008:0:1-f-12
© 2008 Kunwar et.al.