Understanding SoyUnderstanding Soy
Soy has been consumed by Asian cultures for Soy has been consumed by Asian cultures for thousands of years.thousands of years.
Soy is a legume that is so nutritionally complete that Soy is a legume that is so nutritionally complete that it sustained Eastern populations through drought it sustained Eastern populations through drought and famine.and famine.
Composed of:Composed of: Protein Protein - Carbohydrate - Carbohydrate FatFat - Fiber - Fiber PhytonutrientsPhytonutrients - Isoflavones - Isoflavones
Other isoflavone rich foods include garbanzo Other isoflavone rich foods include garbanzo beans and sprouts (Red Clover)beans and sprouts (Red Clover)
The forms of soyThe forms of soy
Soy has been used and studied in various Soy has been used and studied in various forms:forms: Whole soybeans-raw and cookedWhole soybeans-raw and cooked Protein isolates-with balanced and Protein isolates-with balanced and
unbalanced isoflavone contentunbalanced isoflavone content Balanced isoflavone isolatesBalanced isoflavone isolates Single isoflavone isolatesSingle isoflavone isolates
The more imbalanced the isoflavones the The more imbalanced the isoflavones the greater the chance for negative affects.greater the chance for negative affects.
Why is their confusion Why is their confusion around soy?around soy?
Negative articles regarding soy typically Negative articles regarding soy typically focus on only one particular study.focus on only one particular study.
Thorough evaluation of existing Thorough evaluation of existing research will reveal the positive health research will reveal the positive health benefits of soy.benefits of soy.
Also, certain companies and/or Also, certain companies and/or individuals are exploiting negative individuals are exploiting negative research as a marketing tactic.research as a marketing tactic.
Frequently Asked Frequently Asked Questions about SoyQuestions about Soy
Is GMO soy is used in Metagenics products?Is GMO soy is used in Metagenics products? Do Metagenics soy products have the proper balance Do Metagenics soy products have the proper balance
of isoflavones?of isoflavones? Is soy beneficial for tissue health? Menopause? Bone Is soy beneficial for tissue health? Menopause? Bone
health?health? Do you think people are eating too much soy?Do you think people are eating too much soy? Do soy products compromise male reproduction?Do soy products compromise male reproduction? Isn’t it better to use a more complete protein?Isn’t it better to use a more complete protein? Do I have to use fermented soy products to achieve Do I have to use fermented soy products to achieve
therapeutic benefits?therapeutic benefits? Does soy inhibit thyroid function?Does soy inhibit thyroid function? How common is soy allergy?How common is soy allergy?
Is GMO soy is used in Is GMO soy is used in Metagenics products?Metagenics products?
NO. We use only DNA identified soy to NO. We use only DNA identified soy to guarantee the purity of our ingredients.guarantee the purity of our ingredients. We test every batch to ensure we are using We test every batch to ensure we are using
only the purest soy protein.only the purest soy protein. Our “Identity Preserved” soy allows us to Our “Identity Preserved” soy allows us to
trace the source of the raw material and trace the source of the raw material and ensure it is not genetically modified.ensure it is not genetically modified.
Being certified by regulatory agencies of Being certified by regulatory agencies of NNFA, NSF and TGA shows how seriously NNFA, NSF and TGA shows how seriously we take the quality of all of our products.we take the quality of all of our products. Over $2 million spent in 2005 on QC/QA Over $2 million spent in 2005 on QC/QA
Do Metagenics soy products Do Metagenics soy products have a natural balance of have a natural balance of
isoflavones?isoflavones? Yes. Our soy products are evaluated to verify Yes. Our soy products are evaluated to verify
they have natural ratios of the isoflavones they have natural ratios of the isoflavones Genistein and Daidzein. Genistein and Daidzein. Isoflavones from soy are 100 to 1000 times weaker than estradiol.Isoflavones from soy are 100 to 1000 times weaker than estradiol.
Collins. Collins. Steroids 1997;62:365Steroids 1997;62:365
Our soy products carry a 1:1 ratio of these Our soy products carry a 1:1 ratio of these isoflavones which is identical to what is found in isoflavones which is identical to what is found in tofu.tofu.
Our 35 full-time scientists led by Dr. Jeffrey Our 35 full-time scientists led by Dr. Jeffrey Bland are involved in every aspect of product Bland are involved in every aspect of product formulation, research and testing.formulation, research and testing. Over $5 million spent in 2005.Over $5 million spent in 2005.
Is soy beneficial for Is soy beneficial for tissue health?tissue health?
Yes. Soy contains various beneficial agents for tissue Yes. Soy contains various beneficial agents for tissue healthhealth
Kennedy AR. The evidence for soybean products as cancer preventive agents. Kennedy AR. The evidence for soybean products as cancer preventive agents. J NutrJ Nutr 1995;125(3 Suppl):733S-43S. 1995;125(3 Suppl):733S-43S.
Cultures that eat soy have shown an improvement in Cultures that eat soy have shown an improvement in colon and specific hormone-related tissue health colon and specific hormone-related tissue health issues.issues.
Shu XO, Jin F, Dai Q, et al. Soyfood intake during adolescence and subsequent risk of Shu XO, Jin F, Dai Q, et al. Soyfood intake during adolescence and subsequent risk of breast cancer among Chinese women. breast cancer among Chinese women. Cancer Epidemiol Biomarkers PrevCancer Epidemiol Biomarkers Prev 2001;10(5):483-88. 2001;10(5):483-88.
Lamartiniere CA, Moore JB, Brown NM, Thompson R, Hardin MJ, Barnes S. Genistein Lamartiniere CA, Moore JB, Brown NM, Thompson R, Hardin MJ, Barnes S. Genistein suppresses mammary cancer in rats. suppresses mammary cancer in rats. CarcinogenesisCarcinogenesis 1995;16(11):2833-40. 1995;16(11):2833-40.
Human trials involving post-menopausal women Human trials involving post-menopausal women demonstrate a significant shift in healthy estrogen demonstrate a significant shift in healthy estrogen metabolism.metabolism.
Xu X, Duncan AM, Merz BE, Kurzer MS. Xu X, Duncan AM, Merz BE, Kurzer MS. Effects of soy isoflavones on estrogen and Effects of soy isoflavones on estrogen and phytoestrogen metabolism in premenopausal women. phytoestrogen metabolism in premenopausal women. Cancer Epidemiol Biomarkers Cancer Epidemiol Biomarkers PrevPrev 1998;7(12):1101-08. 1998;7(12):1101-08.
Xu X, Duncan AM, Wangen KE, Kurzer MS. Xu X, Duncan AM, Wangen KE, Kurzer MS. Soy consumption alters endogenous Soy consumption alters endogenous estrogen metabolism in postmenopausal women. estrogen metabolism in postmenopausal women. Cancer Epidemiol Biomarkers PrevCancer Epidemiol Biomarkers Prev 2000;9(8):781-86.2000;9(8):781-86.
Is soy beneficial for Is soy beneficial for breast health?breast health?
Research is far from conclusive on this issue and Research is far from conclusive on this issue and researchers are urging caution for womenresearchers are urging caution for women
However, a distinction should be made between the However, a distinction should be made between the clear benefit of soy protein for cardiovascular health clear benefit of soy protein for cardiovascular health and the inconclusive role of isoflavones for breast and the inconclusive role of isoflavones for breast tissue healthtissue health. .
Henkel J. U.S. Food and Drug Administration. Soy: Henkel J. U.S. Food and Drug Administration. Soy: Health claims for soy protein, Health claims for soy protein, questions about other componentsquestions about other components. Available at: . Available at: http://www.fda.gov/fdac/features/2000/300_soy.html. Accessed August 4, 2004. http://www.fda.gov/fdac/features/2000/300_soy.html. Accessed August 4, 2004.
Messina M, Erdman J Jr, Setchell KD. Introduction to and perspectives from the Messina M, Erdman J Jr, Setchell KD. Introduction to and perspectives from the Fifth International Symposium on the Role of Soy in Preventing and Treating Fifth International Symposium on the Role of Soy in Preventing and Treating Chronic Disease. Chronic Disease. J NutrJ Nutr 2004;134(5):1205S-06S. 2004;134(5):1205S-06S.
Xu X, Duncan AM, Merz BE, Kurzer MS. Xu X, Duncan AM, Merz BE, Kurzer MS. Effects of soy isoflavones on estrogen Effects of soy isoflavones on estrogen and phytoestrogen metabolism in premenopausal women. and phytoestrogen metabolism in premenopausal women. Cancer Epidemiol Cancer Epidemiol Biomarkers PrevBiomarkers Prev 1998;7(12):1101-08. 1998;7(12):1101-08.
Xu X, Duncan AM, Wangen KE, Kurzer MS. Xu X, Duncan AM, Wangen KE, Kurzer MS. Soy consumption alters endogenous Soy consumption alters endogenous estrogen metabolism in postmenopausal women. estrogen metabolism in postmenopausal women. Cancer Epidemiol Biomarkers Cancer Epidemiol Biomarkers PrevPrev 2000;9(8):781-86. 2000;9(8):781-86.
Does soy benefit Does soy benefit menopausal women?menopausal women?
Yes. The research shows a great correlation with Yes. The research shows a great correlation with reducing hot flashes and other menopausal issues by reducing hot flashes and other menopausal issues by consuming soy products.consuming soy products.
Consumption of soy protein containing isoflavones Consumption of soy protein containing isoflavones decreased the intensity of hot flashes.decreased the intensity of hot flashes.
Washburn S, Burke GL, Morgan T, Anthony M. Effect of soy protein Washburn S, Burke GL, Morgan T, Anthony M. Effect of soy protein supplementation on serum lipoproteins, blood pressure, and menopausal supplementation on serum lipoproteins, blood pressure, and menopausal symptoms in perimenopausal women. symptoms in perimenopausal women. MenopauseMenopause 1999;6(1):7-13. 1999;6(1):7-13.
The majority of studies in menopausal women have The majority of studies in menopausal women have shown improvement of hot flashes following soy shown improvement of hot flashes following soy consumption.consumption.
The role of isoflavones in menopausal health: consensus opinion of The North The role of isoflavones in menopausal health: consensus opinion of The North American Menopause Society. American Menopause Society. MenopauseMenopause 2000;7(4):215-29. 2000;7(4):215-29.
Eden J. Phytoestrogens and the menopause. Eden J. Phytoestrogens and the menopause. Baillieres Clin Endocrinol MetabBaillieres Clin Endocrinol Metab 1998;12(4):581-87. 1998;12(4):581-87.
Dalais FS, Rice GE, Wahlqvist ML, et al. Dalais FS, Rice GE, Wahlqvist ML, et al. Effects of dietary phytoestrogens in Effects of dietary phytoestrogens in postmenopausal women. postmenopausal women. ClimactericClimacteric 1998;1(2):124-29. 1998;1(2):124-29.
Is soy beneficial for bone Is soy beneficial for bone health?health?
Yes. Studies have shown that the Yes. Studies have shown that the isoflavones that are found in soy stimulate isoflavones that are found in soy stimulate bone formation and reduce bone bone formation and reduce bone breakdown.breakdown.
Soy isoflavones have been found to have a Soy isoflavones have been found to have a positive effect on bone health. positive effect on bone health.
Migliaccio S, Anderson JJ. Isoflavones and skeletal health: are these Migliaccio S, Anderson JJ. Isoflavones and skeletal health: are these molecules ready for clinical application? molecules ready for clinical application? Osteoporos IntOsteoporos Int 2003;14(5):361-68. 2003;14(5):361-68.
Isoflavones stimulate osteoblastic bone Isoflavones stimulate osteoblastic bone formation and inhibit osteoclastic bone formation and inhibit osteoclastic bone breakdown.breakdown.
Brynin R. Soy and its isoflavones: a review of their effects on bone Brynin R. Soy and its isoflavones: a review of their effects on bone density. density. Altern Med RevAltern Med Rev 2002;7(4):317-27. 2002;7(4):317-27.
Do you think people are Do you think people are eating too much soy?eating too much soy?
Americans eat very little soy products when Americans eat very little soy products when compared to Asian populations.compared to Asian populations.
While Asian populations consume an average While Asian populations consume an average of 10 to 50 grams of soy per day, Americans of 10 to 50 grams of soy per day, Americans generally consume only 1 to 3 grams daily.generally consume only 1 to 3 grams daily.
Limer JL, Speirs V. Phyto-oestrogens and breast cancer chemoprevention. Limer JL, Speirs V. Phyto-oestrogens and breast cancer chemoprevention. Breast Breast Cancer ResCancer Res 2004;6(3):119-27. 2004;6(3):119-27.
In fact, one-quarter of Americans reported In fact, one-quarter of Americans reported consuming soy foods once a week or more, consuming soy foods once a week or more, while 38% admitted to never consuming soy while 38% admitted to never consuming soy products. products.
United Soybean Board. National Report, 2004-2005. United Soybean Board. National Report, 2004-2005. Consumer attitudes about Consumer attitudes about nutrition – Insights into nutrition, health, and soyfoodsnutrition – Insights into nutrition, health, and soyfoods . Available at: . Available at: http://www.talksoy.com/pdfs/ConsumerAttitudes2004.pdf. Accessed August 5, 2004.http://www.talksoy.com/pdfs/ConsumerAttitudes2004.pdf. Accessed August 5, 2004.
Do soy products Do soy products compromise male compromise male
reproduction?reproduction? NO. Studies done with balanced soy isoflavones do not NO. Studies done with balanced soy isoflavones do not
show negative impact on male reproduction. show negative impact on male reproduction. These studies done with one isoflavone or by injecting These studies done with one isoflavone or by injecting
isoflavones directly into the blood create much of the isoflavones directly into the blood create much of the negative concern on soy. negative concern on soy.
Genistein was shown in cell cultures to negatively Genistein was shown in cell cultures to negatively impact human sperm's ability to fertilize the female egg. impact human sperm's ability to fertilize the female egg. Professor Lynn Fraser of King's College London, European Society for Human Professor Lynn Fraser of King's College London, European Society for Human
Reproduction and Embryology Reproduction and Embryology
Only when plant estrogens are injected, leading to high Only when plant estrogens are injected, leading to high blood levels are adverse effects seen in research blood levels are adverse effects seen in research animals.animals.
US Center for the Evaluation of Risks to Human Reproduction (CERHR) or the US Center for the Evaluation of Risks to Human Reproduction (CERHR) or the National Institute of Environmental Health Services and National Toxicology National Institute of Environmental Health Services and National Toxicology Program; March 20, 2006.Program; March 20, 2006.
Do soy products Do soy products compromise male compromise male
reproduction?reproduction? Four published clinical trials investigating the Four published clinical trials investigating the
effects of soy isoflavone consumption in men and effects of soy isoflavone consumption in men and reported that there are no adverse effects of soy reported that there are no adverse effects of soy isoflavone consumption on sperm quality.isoflavone consumption on sperm quality.
Persky VW, Turyk ME, Wang L, et al. Persky VW, Turyk ME, Wang L, et al. Effect of soy protein on Effect of soy protein on endogenous hormones in postmenopausal women. endogenous hormones in postmenopausal women. Am J Clin NutrAm J Clin Nutr 2002;75(1):145-53. 2002;75(1):145-53.
Consumption of isoflavone supplements at the level Consumption of isoflavone supplements at the level of 40 mg daily had no effect on semen quality.of 40 mg daily had no effect on semen quality.
Mitchell JH, Cawood E, Kinniburgh D, Provan A, Collins AR, Irvine DS.Mitchell JH, Cawood E, Kinniburgh D, Provan A, Collins AR, Irvine DS.Publication: Clin Sci (Lond). 2001 Jun;100(6):613-8.Publication: Clin Sci (Lond). 2001 Jun;100(6):613-8.
There is no evidence of increased rates of fertility There is no evidence of increased rates of fertility disorders among the Asian population due to soy disorders among the Asian population due to soy consumption.consumption.
Medical foods with soy deliver 17mg of balanced Medical foods with soy deliver 17mg of balanced isoflavones.isoflavones.
Should soy be used for Should soy be used for prostate health?prostate health?
Yes. Research shows overwhelming evidence Yes. Research shows overwhelming evidence of the positive benefits in supporting prostate of the positive benefits in supporting prostate health without adverse effects.health without adverse effects.
Peterson G, Barnes S. Genistein and biochanin A inhibit the growth of human prostate Peterson G, Barnes S. Genistein and biochanin A inhibit the growth of human prostate cancer cells but not epidermal growth factor receptor tyrosine autophosphorylation. cancer cells but not epidermal growth factor receptor tyrosine autophosphorylation. ProstateProstate 1993;22(4):335-45. 1993;22(4):335-45.
Geller J, Sionit L, Partido C, et al. Geller J, Sionit L, Partido C, et al. Genistein inhibits the growth of human-patient BPH and Genistein inhibits the growth of human-patient BPH and prostate cancer in histoculture. prostate cancer in histoculture. ProstateProstate 1998;34(2):75-79. 1998;34(2):75-79.
Barnes S. Effect of genistein on in vitro and in vivo models of cancer. Barnes S. Effect of genistein on in vitro and in vivo models of cancer. J NutrJ Nutr 1995;125(Suppl):777S-83S. 1995;125(Suppl):777S-83S.
Adlercreutz CH, Goldin BR, Gorbach SL, et al. Soybean phytoestrogen intake and cancer Adlercreutz CH, Goldin BR, Gorbach SL, et al. Soybean phytoestrogen intake and cancer risk. risk. J NutrJ Nutr 1995;125(3 Suppl):757S-70S. 1995;125(3 Suppl):757S-70S.
Nagata C, Takatsuka N, Shimizu H, Hayashi H, Akamatsu T, Murase K. Effect of soymilk Nagata C, Takatsuka N, Shimizu H, Hayashi H, Akamatsu T, Murase K. Effect of soymilk consumption on serum estrogen and androgen concentrations in Japanese men. consumption on serum estrogen and androgen concentrations in Japanese men. Cancer Cancer Epidemiol Biomarkers PrevEpidemiol Biomarkers Prev 2001;10(3):179-84. 2001;10(3):179-84.
Habito RC, Montalto J, Leslie E, Ball MJ. Habito RC, Montalto J, Leslie E, Ball MJ. Effects of replacing meat with soyabean in the diet Effects of replacing meat with soyabean in the diet on sex hormone concentrations in healthy adult males. on sex hormone concentrations in healthy adult males. Br J NutrBr J Nutr 2000;84(4):557-63. 2000;84(4):557-63.
Mitchell JH, Cawood E, Kinniburgh D, Provan A, Collins AR, Irvine DS. Effect of a Mitchell JH, Cawood E, Kinniburgh D, Provan A, Collins AR, Irvine DS. Effect of a phytoestrogen food supplement on reproductive health in normal males. phytoestrogen food supplement on reproductive health in normal males. Clin SciClin Sci 2001;100(6):613-18. 2001;100(6):613-18.
Hussain M et al. Hussain M et al. Soy isoflavones in the treatment of prostate cancerSoy isoflavones in the treatment of prostate cancer Nutr Cancer Nutr Cancer 2003;47(2):111-7.2003;47(2):111-7.
Isn’t it better to use a Isn’t it better to use a more complete protein?more complete protein?
Early studies suggested that soy was not a Early studies suggested that soy was not a complete protein source. complete protein source. These early findings These early findings have been shown to be inaccurate.have been shown to be inaccurate.
Soy has the same score as egg white and milk Soy has the same score as egg white and milk protein.protein. Protein Digestibility Corrected Amino Acid Score (PDCAAS), which has been Protein Digestibility Corrected Amino Acid Score (PDCAAS), which has been
adopted by both the FDA and World Health Organization (WHO)adopted by both the FDA and World Health Organization (WHO) Sarwar G, McDonough FE. Evaluation of protein digestibility-corrected amino acid Sarwar G, McDonough FE. Evaluation of protein digestibility-corrected amino acid
score method for assessing protein quality of foods. score method for assessing protein quality of foods. J Assoc Off Anal ChemJ Assoc Off Anal Chem 1990;73(3):347-56. 1990;73(3):347-56.
FAO/WHO/UNU Expert Consultation. FAO/WHO/UNU Expert Consultation. Energy and Protein RequirementsEnergy and Protein Requirements. Geneva: . Geneva: World Health Organization; 1985 (WHO technical report, series 724). World Health Organization; 1985 (WHO technical report, series 724).
U.S. Food and Drug Administration. U.S. Food and Drug Administration. Federal Register.Federal Register. 21 CFR, Part 101, et al. Part III. 21 CFR, Part 101, et al. Part III. Food Labeling, 1991.Food Labeling, 1991.
Does soy inhibit thyroid Does soy inhibit thyroid function?function?
Well-designed human clinical studies have Well-designed human clinical studies have demonstrated that soy has a minimal effect on overall demonstrated that soy has a minimal effect on overall thyroid function in healthy individuals.thyroid function in healthy individuals.
Duncan AM, Underhill KE, Xu X, Lavalleur J, Phipps WR, Kurzer MS. Duncan AM, Underhill KE, Xu X, Lavalleur J, Phipps WR, Kurzer MS. Modest hormonal Modest hormonal effects of soy isoflavones in postmenopausal women. effects of soy isoflavones in postmenopausal women. J Clin Endocrinol MetabJ Clin Endocrinol Metab 1999;84(10):3479-84. 1999;84(10):3479-84.
Persky VW, Turyk ME, Wang L, et al. Persky VW, Turyk ME, Wang L, et al. Effect of soy protein on endogenous hormones in Effect of soy protein on endogenous hormones in postmenopausal women. postmenopausal women. Am J Clin NutrAm J Clin Nutr 2002;75(1):145-53. 2002;75(1):145-53.
UltraMeal Medical Food Program: UltraMeal Medical Food Program: Containing soy protein Containing soy protein (15 grams) with a comprehensive vitamin/mineral blend(15 grams) with a comprehensive vitamin/mineral blend
Patients using the UltraMeal product had no change in their Patients using the UltraMeal product had no change in their TSH levels after 10 weeks. Patients using the popular retail TSH levels after 10 weeks. Patients using the popular retail product showed a significant elevation (150% above product showed a significant elevation (150% above baseline) in their TSH levels.baseline) in their TSH levels. Bland JS, DiBase F, Ronzio R. Physiological effects of a doctor-supervised Bland JS, DiBase F, Ronzio R. Physiological effects of a doctor-supervised
versus and unsupervised over-the-counter weight-loss program. versus and unsupervised over-the-counter weight-loss program. J Nutr MedJ Nutr Med 1992;3:285-931992;3:285-93
Does soy inhibit thyroid Does soy inhibit thyroid function?function?
Amounts greater than 200 mg of isoflavones per day Amounts greater than 200 mg of isoflavones per day may inhibit thyroid hormone synthesis in susceptible may inhibit thyroid hormone synthesis in susceptible people. (thyroid issues/low iodine)people. (thyroid issues/low iodine)
Certain studies suggest that soy and soy isoflavones Certain studies suggest that soy and soy isoflavones inhibit the production of thyroid hormones in inhibit the production of thyroid hormones in individuals with thyroid issues.individuals with thyroid issues. Chang HC, Doerge DR. Dietary genistein inactivates rat thyroid peroxidase in vivo Chang HC, Doerge DR. Dietary genistein inactivates rat thyroid peroxidase in vivo
without an apparent hypothyroid effect. without an apparent hypothyroid effect. Toxicol Appl PharmacolToxicol Appl Pharmacol 2000;168(3):244-52. 2000;168(3):244-52.
Approximately 10 million Americans or 3% of the Approximately 10 million Americans or 3% of the population have thyroid issues.population have thyroid issues.
Alternatives to soy based medical foods are available Alternatives to soy based medical foods are available for these individuals.for these individuals.
Isn’t soy more allergenic Isn’t soy more allergenic than other proteins?than other proteins?
Soy proteins tend to be less reactive than Soy proteins tend to be less reactive than many other food proteins. In fact, soy has many other food proteins. In fact, soy has been used as an alternative for infants with been used as an alternative for infants with allergies to cow’s milk.allergies to cow’s milk. Cordle CT. Soy protein allergy: incidence and relative severity. Cordle CT. Soy protein allergy: incidence and relative severity. J NutrJ Nutr
2004;134(5):1213S-19S. 2004;134(5):1213S-19S.
A meta-analysis of 17 studies of allergy A meta-analysis of 17 studies of allergy patterns of high-risk infants revealed soy patterns of high-risk infants revealed soy allergy occurring in 3% to 4% of subjects allergy occurring in 3% to 4% of subjects versus 25% for cow’s milk. versus 25% for cow’s milk. Cantani A, Lucenti P. Natural history of soy allergy and/or intolerance in children, Cantani A, Lucenti P. Natural history of soy allergy and/or intolerance in children,
and clinical use of soy-protein formulas. and clinical use of soy-protein formulas. Pediatr Allergy ImmunolPediatr Allergy Immunol 1997;8(2):59-74. 1997;8(2):59-74.
Do I have to use fermented Do I have to use fermented soy products to achieve soy products to achieve therapeutic benefits?therapeutic benefits?
No. The majority of studies around the world No. The majority of studies around the world show beneficial effects of soy.show beneficial effects of soy.
Our research studies confirm those findings Our research studies confirm those findings for areas including:for areas including: Blood Sugar Blood Sugar Body compositionBody composition Preserving muscle mass during weight lossPreserving muscle mass during weight loss Cardiovascular risk reductionCardiovascular risk reduction
The Functional Medicine The Functional Medicine Research CenterResearch Center
We are the only company in the We are the only company in the professional market to operate a patient professional market to operate a patient clinic.clinic.
In 2004-2005 the FMRC conducted over In 2004-2005 the FMRC conducted over 5,000 patient visits.5,000 patient visits. It allows us to test our products for safety It allows us to test our products for safety
and efficacy before they reach your patients.and efficacy before they reach your patients. Many companies use your patients to test Many companies use your patients to test
their products.their products.
UltraGlycemX medical food UltraGlycemX medical food positively affects blood positively affects blood
sugarsugar UltraGlycemX Medical FoodUltraGlycemX Medical Food
Contains soy protein (15 grams) with a Contains soy protein (15 grams) with a comprehensive vitamin/mineral blendcomprehensive vitamin/mineral blend
Clinically Shown to:Clinically Shown to: Significantly improve Significantly improve
fasting and 2-hour postprandial insulinfasting and 2-hour postprandial insulin Triglycerides and cholesterol levelsTriglycerides and cholesterol levels Body compositionBody composition Study lasted 8 weeks and 37 insulin resistant Study lasted 8 weeks and 37 insulin resistant
patients participatedpatients participated
UltraMeal medical food UltraMeal medical food positively affects body positively affects body
compositioncomposition UltraMeal Medical FoodUltraMeal Medical Food
Contains soy protein (15 grams) with a comprehensive Contains soy protein (15 grams) with a comprehensive vitamin/mineral blendvitamin/mineral blend
Published Peer Review Study:Published Peer Review Study: A 10 week study with 34 patients showed A 10 week study with 34 patients showed Patients Patients
on UltraMeal lost an average of 13 lbs with zero on UltraMeal lost an average of 13 lbs with zero muscle lost.muscle lost.
Compared to a popular retail product in which Compared to a popular retail product in which patients lost similar weight but lost 85% of it as patients lost similar weight but lost 85% of it as muscle.muscle. Bland JS, DiBase F, Ronzio R. Physiological effects of a Bland JS, DiBase F, Ronzio R. Physiological effects of a
doctor-supervised versus and unsupervised over-the-counter doctor-supervised versus and unsupervised over-the-counter weight-loss program. weight-loss program. J Nutr MedJ Nutr Med 1992;3:285-93 1992;3:285-93
UltraMeal medical food UltraMeal medical food positively affects body positively affects body
compositioncomposition UltraMeal Medical Food UltraMeal Medical Food Published Peer Reviewed Study:Published Peer Reviewed Study:
A University of Oregon study showed A University of Oregon study showed significant change in body composition significant change in body composition over over 7 weeks.7 weeks.
34 patients lost an average of 14.1 lbs of 34 patients lost an average of 14.1 lbs of fat while gaining 0.9 lbs of muscle.fat while gaining 0.9 lbs of muscle. Hackman RM, Ellis BK, Brown RL. Phosphorous magnetic Hackman RM, Ellis BK, Brown RL. Phosphorous magnetic
resonance spectra and changes in body composition resonance spectra and changes in body composition during weight loss. during weight loss. J Am Coll NutrJ Am Coll Nutr 1994; 13(3)243-250 1994; 13(3)243-250
UltraMeal Plus program UltraMeal Plus program affects body composition affects body composition and cardiovascular healthand cardiovascular health UltraMeal Plus Medical FoodUltraMeal Plus Medical Food
Incorporates soy protein and phytosterols with a Incorporates soy protein and phytosterols with a comprehensive vitamin and mineral blendcomprehensive vitamin and mineral blend
Published Peer Reviewed Study:Published Peer Reviewed Study: 42 post-menopausal women were studied for 12 42 post-menopausal women were studied for 12
weeks and the results showed statistically weeks and the results showed statistically significant improvement in 14 independent significant improvement in 14 independent cardiovascular risk markers cardiovascular risk markers Lukaczer D, Liska DJ, Lerman RH. et al. Effect of a low Lukaczer D, Liska DJ, Lerman RH. et al. Effect of a low
glycemic index diet with soy protein and phytosterols on glycemic index diet with soy protein and phytosterols on CVD risk factors in postmenopausal women. CVD risk factors in postmenopausal women. Nutrition Nutrition 2006 2006 104-113104-113
UltraMeal Plus shows UltraMeal Plus shows significant changes in key significant changes in key
cardiovascular markerscardiovascular markers WeightWeight -14.8 lbs-14.8 lbs Lean MuscleLean Muscle +2.28 lbs+2.28 lbs Total CholesterolTotal Cholesterol -16%-16% LDL CholesterolLDL Cholesterol -15%-15% HDL CholesterolHDL Cholesterol +6%+6% tChol/HDLtChol/HDL -20%-20% TG/HDLTG/HDL -56%-56% hsCRP hsCRP -34%-34% HA1C HA1C -3.4%-3.4% InsulinInsulin -26%-26%
We support the use of We support the use of soy soy
• Due to the large amount of reported safety and efficacy studies.
• Its long history of safe consumption by Asian populations.
• The FDA health claim regarding soy protein and its potential to reduce the risk of heart disease.
• Substantial data regarding the benefits of soy in cardiovascular health, prostate health, menopausal symptom relief, and osteoporosis prevention as well as other important areas.
We have options to We have options to benefit every type of benefit every type of
patientpatient Many companies just say why one protein or ingredient is better than Many companies just say why one protein or ingredient is better than
another. another. Thyriod issues and soy allergy patientsThyriod issues and soy allergy patients
UltraMeal WheyUltraMeal Whey UltraMeal RiceUltraMeal Rice UltraClear Medical FoodUltraClear Medical Food UltraClear Plus Medical FoodUltraClear Plus Medical Food UltraInflamX Medical FoodUltraInflamX Medical Food
Breast tissue health optionsBreast tissue health options Estrium Medical FoodEstrium Medical Food UltraMeal Whey UltraMeal Whey UltraMeal RiceUltraMeal Rice UltraClear Medical FoodUltraClear Medical Food UltraClear Plus Medical FoodUltraClear Plus Medical Food UltraInflamX Medical FoodUltraInflamX Medical Food
Decisions must be based on Decisions must be based on a balanced review of a balanced review of
researchresearch
Metagenics will always select the best Metagenics will always select the best ingredients and method of delivery to meet ingredients and method of delivery to meet the needs of your patientsthe needs of your patients Variety of proteins in our medical foodsVariety of proteins in our medical foods Use of powders, tablets, capsules and liquids Use of powders, tablets, capsules and liquids
in different products to ensure effectiveness in different products to ensure effectiveness as well as improved compliance.as well as improved compliance.
At Metagenics, we're in the At Metagenics, we're in the health business - Not the pill health business - Not the pill
businessbusiness In the health business, safety and In the health business, safety and
effectiveness are top priority because effectiveness are top priority because there is a lot riding on the quality of the there is a lot riding on the quality of the products we make:products we make:1.1. Your patient’s health. Your patient’s health.
2.2. The success of the nutritional therapy you The success of the nutritional therapy you recommend. recommend.
3.3. Your credibility as a health professional. Your credibility as a health professional.
““Genetic Potential Through Genetic Potential Through Nutrition”Nutrition”
We invest more in research and quality than We invest more in research and quality than anyone else in our industry. anyone else in our industry.
Our medical foods are just one example of how Our medical foods are just one example of how we distinguish ourselves in this industry.we distinguish ourselves in this industry.
Always True to Our MissionAlways True to Our MissionSince our inception in 1983, we have never Since our inception in 1983, we have never
deviated from our founding idea - "the deviated from our founding idea - "the patient's best interests must be served."patient's best interests must be served."
