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Wonderful World of Bicarbonate and CO2Posted by Dr Sircus on May 27, 2013 | Filed under Medicine
My book Sodium Bicarbonate is not only about sodium bicarbonate (baking soda), but also
about magnesium bicarbonate and to a lesser degree potassium bicarbonate and calcium
bicarbonate. However, the star of the show in this book is bicarbonate. The second star of
the show is carbon dioxide (CO2). Most of the conjugate acid of bicarbonate is in the form
of dissolved carbon dioxide. The rapid and direct inter-conversion of dissolved CO2 and
bicarbonate ion is catalyzed by the enzyme carbonic anhydrase.
Carbon dioxide is a neutral, nonpolar molecule, and can readily diffuse across membranes.
Bicarbonate is a charged species of CO2, and does not cross membranes at a significant
rate unless facilitated by trans-membrane channels like the magnesium calcium channel.
Baking soda (sodium bicarbonate) immediately reacts when it mixes with stomach acid.
NaHCO(3) + HCl > NaCl + H(2)0 + CO(2). That is: Sodium bicarbonate + stomach acid
yields salt + water + carbon dioxide.
When we talk about bicarbonate we are talking about CO2, because that is what sodium
bicarbonate turns to when it reaches the stomach causing an increase in stomach acid
production as well as an increase in bicarbonates in the blood. The bicarbonate ion is
HCO3-. Bicarbonate is an important buffer found in blood. Carbon dioxide is present in the
blood in a number of forms such as bicarbonate, dissolved carbon dioxide and carbonic
acid, of which 90% is bicarbonate or HCO3.
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CO2, in the form of bicarbonate, is directly involved in light reactions . This
bicarbonate effect influences molecular processes. The role of carbon dioxide (CO2) or
bicarbonate in the photosynthesis was clear to researchers from the very beginning of the
history of photosynthesis. Bicarbonate in plants probably links cell metabolism to
photosynthetic electron flow.
Joseph Priestley observed in 1775 that a green matter deposited on the walls of water
containers, formed bubbles of pure dephlogisticated air (oxygen). [1] While Ingen-Housz (
in 1779, 1796) discovered the importance of light in this process, it was Senebier in 1782
who demonstrated that the production of oxygen by plants depends on the presence
of CO2 .[2] Carbon dioxide is, in fact, a more fundamental component of living matter than
is oxygen.
Dr Alina Vasiljeva and Dr David Nias wrote, At the end of the 19th century, scientists Bohr
and Verigo discovered what seemed a strange law: a decreased level of carbon dioxide
in the blood leads to decreased oxygen supply to the cells in the body including the
brain, heart, kidneys etc. Carbon dioxide (CO2) was found to be responsible for the bond
between oxygen and haemoglobin. If the level of carbon dioxide in the blood is lower than
normal, then this leads to difficulties in releasing oxygen from haemoglobin. Hence the
Verigo- Bohr law.
Also in the 19th century, Zuntz, in Berlin, recognized that carbon dioxide, unlike oxygen, is
not carried by hemoglobin. He showed that, in the blood, carbon dioxide is combined withbases, chiefly as sodium bicarbonate which plays a part in acid-alkaline balance. All the
carbon dioxide is dissolved in the plasma, both in simple solution and that combined with
alkali into the bicarbonates.
Oxygen and carbon dioxide are not antagonistic. A gain of one gas in the blood does not
necessarily involve a corresponding loss of the other. The blood may be high or low in both
gases. Under clinical conditions, low oxygen and low carbon dioxide generally occur
together. Therapeutic increase of carbon dioxide, by inhalation of this gas diluted in air, is
often an effective means of improving the oxygenation of the blood and tissues. Under
clinical conditions, low oxygen and low carbon dioxide generally occur
together. Therapeutic increase of carbon dioxide, by inhalation of this gas diluted in
air, is often an effective means of improving the oxygenation of the blood and
tissues". [3]
The story of bicarbonate and CO2 is a fascinating one full of surprises. My mentor Dr.
Christopher Hills (spirulina man) used to tell us students that heaven was exactly upside
down to life on earth so if you want to get there do everything opposite to everyone else.
When it come s to bicarbonate and CO2 and Oxygen its the same story. What we think
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about CO2 and thus bicarbonate is wrong. Bicarbonate helps our good cells stay alive and
kicks the bad, spent or cancerous cells to their grave.
If you talk to Al Gore he will lead you to believe that CO2 is the enemy of mankind. CO2 is
actually a planet-saving nutrient that could multiply food production rates and feed the
world more nutritious, healthy plants.
CO2 is a vital nutrient for food crops which is the same as saying bicarbonate is vital for
food crops. Greenhouse operators know something that the government does not want you
to know: and that is that they actually buy carbon dioxide and inject it into their
greenhouses in order to maximize plant growth.
If we are under the illusion that bicarbonate and CO2 are poisonous, then we will not be
able to see or understand that bicarbonate has the power to restore electron flow and O2
evolution. There is a lot of power in the bicarbonate ion including oxygen generation power.
Thus we should not be surprised to learn that bicarbonate increases tumor pH and inhibits
spontaneous metastases.
People who live at very high altitudes live significantly longer;
they have a lower incidence of cancer [ 4 ]
and heart disease, [ 5 ] and other
degenerative conditions, than people who live near sea level.
At high altitude CO2 is in greater presence and O2 is in less. A Russian doctor namedKonstantin Buteyko is most responsible for drawing attention to the importance of carbon
dioxide for body metabolism and how the lack of it can cause chronic diseases; this
constitutes a major breakthrough in medical science. A molecule of carbon dioxide (CO2)
consists of one carbon and two oxygen atoms. Colorless and odorless, it is hard to detect.
The amount of carbon dioxide in the atmosphere has been in flux throughout the Earths
history.
The greatest deceivers that ever walked the earth are now declaring CO2 to be a
poison when it is in fact a medicine. Dr. Ray Peat says, Carbon dioxide is being used
increasingly to prevent inflammation and edema. For example, it can be used to prevent
adhesions during abdominal surgery, and to protect the lungs during mechanical
ventilation. It inhibits the formation of inflammatory cytokines and prostaglandins [6] and
reduces the leakiness of the intestine. [7] Some experiments show that as it decreases the
production of some inflammatory materials by macrophages, [8] including lactate, it causes
macrophages to activate phagocytic neutrophils, and to increase their number and
activity. [9]
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Dr. M. Persson and Dr. Van der Linden have demonstrated that carbon dioxide gas
protects against tissue damage in the operative field by maintaining humidity and
temperature in the open-heart surgery-related model environment. [10 ] These scientists are
saying that carbon dioxide insufflation into the abdominal cavity results in the reduction of
oxidative stress .
In 2009 The Environmental Protection Agency formally declared carbon dioxide and five
other heat-trapping gases to be pollutants that threaten public health and welfare, setting in
motion a process that will regulate the gases blamed for global warming. The E.P.A. said
the science supporting its so- called endangerment finding was compelling and
overwhelming.
Dr. Gerald Marsh tells us that five hundred million years ago, carbon dioxide concentrations
were over 13 times current levels; and not until about 20 million years ago did carbon
dioxide levels drop to a little less than twice what they are today. [11 ] Since 1750 the
concentration in the air has risen from of CO2 278 parts per million (ppm) to more than 380
ppm, making it easier for plants to acquire the CO2 needed for rapid
growth. Scientists generally suggest that raised CO2 levels will boost the yields of
mainstream crops, such as maize, rice and soy, by about 13 per cent.
According to the Verigo-Bohr effect, we can state
that a CO2 deficit caused by deep breathing
leads to oxygen starvation in the cells of the body.
Thus it is an absolute scientific fumble to peg carbon dioxide as a poisonous gas and
ridicu lous doctors, who dont know much of anything about bicarbonate and CO2 to come
out against sodium bicarbonate and its use in cancer. If its good enough to keep people
alive while chemotherapy chemicals (very acid) are pumped into the blood stream its more
than good enough for use in the treatment of cancer, which is always pH sensitive
according to all the science.
Dr. Peat concludes, On a slightly longer time scale, a reduction of carbon dioxide canincrease the production of lactic acid, which is a promoter of inflammation and
fibrosis. A prolonged decrease in carbon dioxide can increase the susceptibility of proteins
to glycation. The local concentration of carbon dioxide in specific tissues and organs can be
adjusted by nervous and hormonal activation or inhibition of the carbonic anhydrase
enzymes, that accelerate the conversion of CO2 to carbonic acid, H2CO3. The activity of
carbonic anhydrase can determine the density and strength of the skeleton, the excitability
of nerves, the accumulation of water, and can regulate the structure and function of the
tissues and organs. Ordinarily, carbon dioxide and bicarbonate are thought of only inrelation to the regulation of pH, and only in a very general way. Because of the importance
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of keeping the pH of the blood within a narrow range, carbon dioxide is commonly thought
of as a toxin, because an excess can cause unconsciousness and acidosis. But increasing
carbon dioxide doesnt necessarily ca use acidosis, and acidosis caused by carbon dioxide
isnt as harmful as lactic acidosis.
Conclusion
The change of pH value causes the stomach to produce hydrochloric acid that enters the
stomach, and the bicarbonates enter the bloodstream. When we say that we alkalize our
body, we dont necessarily mean increasing our saliva pH or urine pH; it means increasing
the bicarbonates in our blood. The blood pH does not change, but the ability of our blood to
neutralize acid in the body increases quite dramatically. [12 ] Since bicarbonates enter the
bloodstream only when the stomach produces hydrochloric acid, it is important that we
drink as high pH value alkaline water as possible, and forget about allopathic
pharmaceutical thinking and just use the baking soda as needed.
In the January/February 2003 issue of American Industrial Hygiene Association Journal, Dr.
Gospodinka R. Pradova published the result of a 10-year study of industrial pollution in
Bulgaria. The study compares two groups of people in a plastic manufacturing plant: one
group working in the plant with chemical pollution, the other in the non-polluted office
environment of the same company. The conclusion shows that people living/working in a
polluted environment have fewer amounts of bicarbonates in their blood than people
working in a clean environment .
We live in a world that was changed from an agricultural environment to an industrial
environment, which produces more pollution. Our stressful life-styles create more acid,
which causes us to use up more bicarbonate. The medical society considers the reduction
of bicarbonates in the blood as an inevitable fact of aging.
I and other doctors argue that the reduction of bicarbonates in the blood is the cause
of aging and diseases, not the result of aging . As long as we can replenish
bicarbonates in the blood, we dont have to age so fast. Tak ing high dosages of
magnesium bicarbonate is not as alkalizing as taking sodium bicarbonate but in terms of
anti-aging effect magnesium bicarbonate would easily take the prize. The most important
function of alkaline water is to increase bicarbonates in the blood because we lose
bicarbonates as we age .
Since bicarbonates enter the bloodstream only when the stomach produces hydrochloric
acid, it is important that we drink as much mineral rich alkaline water as possible. On an
empty stomach, the stomach pH value may be high but the amount (volume) of
hydrochloric acid in the stomach is small; therefore, drinking high pH (9.5 to 10) alkaline
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water will raise the stomach pH relatively high. This causes the stomach to produce more
hydrochloric acid, allowing more bicarbonate to enter the bloodstream.
[1] Priestley, 1776
[2] Discovering the Secrets of Photosynthesis :http://users.rcn.com/jkimball.ma.ultranet/BiologyPages/P/Photosynthesis_hi
story.html
[3] Henderson, Y. Carbon Dioxide. Article in Encyclopedia of Medicine. 1940.
[4] Weinberg, et al., 1987
[5] Mortimer, et al., 1977
[6] Peltekova, et al., 2010, Peng, et al., 2009, Persson & van den Linden, 2009
[7] Morisaki, et al., 2009
[8] TNF: Lang, et al., 2005[9] Billert, et al., 2003, Baev & Kuprava, 1997
[10 ] CO2 Field Flooding May Also Reduce Oxidative Stress in Open Surgery;
Masahiko Tsuchiya , MD, PhD et al; A & A August 2009;vol. 109 no. 2 683-684
http://www.anesthesia-analgesia.org/cgi/activate/basic
[11 ] By Dr. Gerald Marsh : Five hundred million years ago, carbon dioxide concentrations
were over 13 times current levels; and not until about 20 million years ago did carbon
dioxide levels dropped to a little less than twice what they are today. It is possible that
moderately increased carbon dioxide concentrations could extend the current interglacialperiod. But we have not reached the level required yet, nor do we know the optimum level
to reach. So, rather than call for arbitrary limits on carbon dioxide emissions, perhaps the
best thing the UNs Intergovernmental Panel on Climate Change and the climatology
community in general could do is spend their efforts on determining the optimal range of
carbon dioxide needed to extend the current interglacial period indefinitely. We ought to
carefully consider this possibility before we wipe out our current prosperity by spending
trillions of dollars to combat a perceived global warming threat that may well prove to be
only a will-o-the-wisp. Dr. Gerald Marsh is a retired physicist from the Argonne NationalLaboratory and a former consultant to the Department of Defense on strategic nuclear
technology and policy in the Reagan, Bush, and Clinton Administration.
[12 ] ALKALINE WATER AND STOMACH ACID; Sang Whang; Science & Health Article
26; Feb 23 , 2012; http://www.sangwhang.org/?p=247
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Dr. Mark Sircus, Ac., OMD, DM (P)Director International Medical Veritas Association
Doctor of Oriental and Pastoral Medicine