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  • 7/25/2019 Dr. Eskina FOZ Presentation ESCRS

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    Erika N. Eskina, MD1

    ,Victoria Parshina1,Olga Mironenko, PhD1

    Yuri Kolmakov1

    Samuel Arba-Mosquera, PhD2,*

    (1) Laser Surgery Clinic SPHERE, Moscow, Russi

    (2) SCHWIND eye-tech-solutions, Kleinostheim, Germ

    FINANCIAL DISCLOSURE:

    The authors have no financial or proprietary interest in a product, method, or material described.Dr. Arba Mosquera and Thomas Magnago are employees of SCHWIND eye-tech-solutions.

    Aspherical optical zones:

    The effective optical zone with the Schwind

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    Purpose:To evaluate the functional optical zone (FOZ) and influencing parameters among eyes that u

    treatments for myopic astigmatism with PRK , TransPRK or LASIK.

    Settings:

    Prof. Erika N. Eskina, MD, Laser Surgery Clinic SPHERE, Moscow, RussiMethods:

    16 patients (32 eyes) treated with

    16 patients (32 eyes) treated with

    16 patients (32 eyes) treated with LASIK using Pendular microkeratome (SCHWIND eye

    using the SCHWIND AMARIS flying-spot excimer laser system (SCHWIND eye-tech-solutionsix-month.

    We analysed the influence of the following parameters:

    OZ Planned, FOZ preop, K readings in 4 mm zone preop, SPH inputted, CYL inputted, pachy

    of the cornea, age and type of operation

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    Parameters and Statistics

    Clinical outcomes were evaluated in terms of functional optical zone (FOZ), eff

    zone (EOZ), planned optical zone (POZ),

    POZ=Optical zone selected in the software where the full amount of refractive

    applied.

    FOZ = defined as the area (diameter) where the RMS HO value exceeds 0.50D th

    search starts from the center to the periphery of each map).

    EOZ = post-op FOZ

    Multilinear regression analyses started with full degrees of freedoapplied stepwise regression

    a P value less than 0.05 was considered statistically significan

    We also used Ordinary least square method, Mann-Whitney U-t

    Coefficient of determination (R2) and Wilcoxon signed-rank te

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    Group description

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    RESULTS - Optical Zone

    The level of significance in difference in OZ postOp and planned TransPRK and PRK g

    For PRK and LASIK groups is 9%

    For LASIK and TransPRK is 68% (not significant at all)

    OZ PostOp OZ Planned OZ PreOp

    Planned OZ

    deviationChange of OZ

    postop

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    P

    POZ deviation in a relation to ablation depth and E

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    POZ deviation in a relation to K readings and EOZ

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    RESULTSEOZ (planned) deviation in TransPRK Grou

    Scattergramm represents the reduction in the effective OZ in majority of

    3

    4

    5

    6

    7

    8

    9

    1 3 5 7 9 11 13 15 17 19 21 23 25 27 29 31

    OZ,mm

    CASES

    OZ plan OZ post OP

    3

    4

    5

    6

    7

    8

    9

    3 4 5 6

    OZpostOP

    OZ plan

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    RESULTSEOZ (planned) deviation in PRK Group

    3

    4

    5

    6

    7

    8

    9

    1 3 5 7 9 11 13 15 17 19 21 23 25 27 29 31

    OZ,mm

    CASES

    OZ plan OZ post OP

    3

    4

    5

    6

    7

    8

    9

    3 4 5 6

    OZpostOP

    OZ plan

    Scattergramm represents the reduction in the effective OZ in all cas

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    3

    4

    5

    6

    7

    8

    9

    1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24

    OZ,mm

    CASES

    OZ plan OZ post OP

    3

    4

    5

    6

    7

    8

    9

    3 4 5 6

    OZpostOP

    OZ plan

    RESULTSEOZ (planned) deviation in LASIKGroup

    Scattergramm represents the reduction in the effective OZ in majority of

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    Multip

    an

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    EOZ planning

    EOZpostOP = 3.144 + 0.688*OZ0.170*OZpreOP

    i + 0.393*SPH

    i + 0.17

    0.003*PACHi0.058*K2i0,008*Agei+ 0.0.461*D2i

    where:

    OZplanOZ planned, PACHpachymetry in the center of the coreading in the flat meridian;Agepatient age; D1is a binary pathere is a PRK planned,0if there is other type of surgery plann

    binary parameter =1 if there is a TransPRK planned, 0 if there issurgery planned

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    EOZ planning

    C

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    Conclusion The results of the analysis offer us a possibility to make a real planning of OZ postop and incr

    optics for patienrs operated

    The mathematical modeling of the factors, which influencing the EOZ could be described by th

    EOZpostOP = 3.144 + 0.688*OZplan + 0.170*OZpreOPi+ 0.393*SPHi+ 0.

    0.003*PACHi0.058*K2i0,008*Agei+ 0.319*D1i+ 0.461*D2

    Take home message:

    Decreasing of EOZ means only higher, than was planned, level of aberr

    ablation

    EOZ decreasing with increasing a level of myopia and astigmatism.

    Planning an additional 1 mm OZ you should input at least for PRK 1,13 m

    1,09 mm and for LASIK 1,06 mm

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    Thank you for your kind attention