Dr Minshad AnsariFounder & CEO Bionema

“to address the pressing need of

developing alternatives to

chemical crop protection”

The Global Challenge

Innovation (Part I)

Innovative Technologies – Products & Services

Innovation (Part II)

Innovative Formulations & Applications

Collaboration – To Deliver Solutions

Technology Adoption

The Biopesticide Summit is an international platform

for collaboration, partnership and advancement of

the industry and an integral part of the World

Biopesticide Forum

The Biopesticide Awards recognise the

greatest achievements in the field of

biocontrol across the world

Our mission is to bridge the gap between

academia & industry globally to ensure

successful innovation, commercialisation

by offering a unique platform to

collaborate

Mission

The designations employed and the presentation of material in the maps do not imply the expression of any opinion whatsoever on the part of FAO concerning

the legal or constitutional status of any country, territory or sea area, or concerning the delimitation of frontiers. South Sudan declared its independence on July

9, 2011. Due to data availability, the assessment presented in the map for Sudan and South Sudan reflects the situation up to 2011 for the former Sudan.

Pesticides usage

by country (1990-2016)

Pesticide usage

– (%) 1990-2016

Pesticides usage

by continent (1990-2016)

Pesticides use by country

(1990-2016)

• 54 different pesticides - spinach, five linked to cancer

• Peaches and pears have the most pesticides

• 47 residues -apples, including 16 suspected hormone

disruptors

Pesticide in food

http://www.newraleigh.com/articles/archive/toxic-free-tip-of-the-week-cost-of-tomatoes/

hardinmd.lib.uiowa.edu/dermnet/skincancer1.html

Increases risk of skin cancer

Breast cancer

Harmful to reproduction

Endocrine disruptor

Deformities

Foetal defects

Neuronal disorders

Cancer

*Gilden RC, Huffling K, Sattler B

(2010). Pesticides and health

risks. J Obstet Gynecol Neonatal

Nurs 39 (1): 103–10.

Harmful to human health

Biopesticides are certain types of pesticides derived from

natural materials such as animals, plants, bacteria, and certain

minerals - Environmental Protection Agency (EPA)

• Microbial - micro-organism (fungi, bacteria, viruses &

protozoa)

• Biochemical - Plant extracts, pheromones, soaps and fatty

acids, natural plant growth regulators (PGR) Avermectin,

Pyrethrins, Spinocid from natural products but not

biopesticides

• Natural enemies - Parasitoids, predators & pathogens of

pests

• Plant incorporated protectants - pesticide substances

produced by plants containing added genetic material

What are Biopesticides?

➢ EU regulations are driving change -

insecticides withdrawn from the market

(Imidacloprid, 2013; Chlorpyrifos, 2015)

➢ EU directives – reduced use of

pesticide and promotion of biologically

based approach as a part of

integrated pest management

➢ Pests and diseases are developing

resistance to current pesticides

➢ Consumers demands for organic good

➢ Pesticides are harmful to human health

- cancers, tumors, birth defects -

and the environment

Toxic pesticides – insect resistance and human health issues

Why Biopesticides?

Biopesticides

Bioinsecticides

Micro-organisms

Fungi

Bacteria

Virus

Protozoan

Macro-organisms

Predators, parasitoids &

mites

Nematodes

Semiochemicals Botanicals

Biofungicides Bioherbicides Bionematicides

Biopesticide types

37.5

46.1

51.954.8

58.5

65.3

75.9

81.8

2011 2012 2013 2014 2015 2017 2019 2020

Global Pesticide market ($b)

3.0

6.64

2018 2023

Global Biopesticide market ($b)

Trends in biopesticides

development

Microbial pesticide

expected to dominate

biopesticide market

Type 2013 2014 2015-e 2020-p CAGR (2015–20)

Bioinsecticides 571.4 650.4 757.0 1,761.9 18.4%

Bioherbicides 387.0 441.3 514.7 1,236.6 19.2%

Biofungicides 293.6 339.3 400.8 1,033.0 20.8%

Bionematicides 66.1 74.4 85.5 189.0 17.2%

Others* 69.6 74.5 80.9 136.6 11.1%

Total 1,387.7 1,579.9 1,838.8 4,357.2 18.8%

Biopesticides market size, by type 2013-2020 (GBP million)

*Others include sulfur, oil, insect repellent, moth control, and other biochemicals

Source: MarketsandMarkets analysis

Market details Types

Biopesticide market share

(value) by region -2014

All contents © copyright 2016 Bionema LimitedFrance - fastest growth of biopesticide in Europe

Biopesticide growth-

worldwide

• To date >400 active ingredients and 1250 products

based on these active ingredients have been

registered across the world

• Products based on various Bacillus thuringensis strains

dominate the market

• Other major products are based on Beauveria,

Metarhizium, Trichoderma, Bacillus subtilis, B. firmus,

Pseudomonas flourescens and entomopathogenic

NPV

Biopesticide use

Year Acquiring Company Value at sale

USD m

Company acquired USD

2016 Bayer - Monsanto 66 b

2016 InVivo AgroSciences - Syngenta Bioline -

2016 ChemChina - Syngenta AG 43 b

2015 Valagro - SriBiotech -

2014 Marrone Bio Innovations collaboration Valagro -

2014 Monsanto - Tekmira's delivery tech-

biopesticides

16.5 m

2013 Monsanto paid - Novozymes ongoing

biopesticide business

300 m

2013 Bayer - Prophyta 27.9 m

2012 Valent BioSciences Corp. - Pace Int. LLC 65 m

2012 BASF 250 Becker Underwood 1.02 b

2012 Syngenta 27 Pasteuria Bioscience 100 m

2012 Bayer CropScience 40 AgraQuest 425 m

2011 Monsanto's - Beeologics 125 m

2011 Monsanto's - Divergence 75 m

Acquired companies paid 5-10x on their sale value

Key Acquisitions

Biopesticide market: M&A

• Polaris Partner: Venture capital firm with passion for innovation that has relationships with outstanding

visionaries principally in technology and healthcare.

• ARCH Venture Partners: Premier provider of seed and early stage venture capital for technology firms,

with a special competence in co-founding and building firms from start up.

• Harris and Harris Group: Venture capital company specializing in nanotechnology and Microsystems

that operates as a business development company under the Investment Company Act of 1940.

• The Bill and Melinda Gates Foundation: The Bill & Melinda Gates Foundation is dedicated to the

idea that all people deserve the chance to live health productive lives. Further information an be found at gatesfoundation.org.

• The University of Texas investment Management Company (UTIMCO): UTIMCO is a

501(c)(3) external investment management corporation formed to oversee investments for The University of Texas and Texas A&M Systems. Created in March 1996, UTIMCO was the test external investment corporation formed by a public university system.

• Pontifax Global Food and Agriculture Technology Fund (Pontifax Ag Tech): Pontifax

AgTech is a pioneering growth capital Investor in food and agriculture technology.

• AgBiome has 3 strategic investors. These firms receive no special rights for their equity investments.

• Monsanto Growth Ventures: Venture capital arm of Monsanto that invests in startup companies with

the potential to create new technologies for farmers.

• Syngenta Ventures: Venture capital arm of Syngenta that invests in early stage companies with the

potential to help growers around the world farm more productively.

• Novozymes

Example: Investors in AgBio

Thank you

Bionema Limited,

Institute of Life Science 1,

Swansea University, Singleton Park,

Swansea SA2 8PP, UK

Tel: 01792 606916 / 07936450606

Email: m.a.ansari@bionema.com

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