Join us in Chicago, for the latest innovativeand inspiring cancer research from aroundthe world…

THEAACRANNUALMEETING2018!

The AACR Annual Meeting highlights the work of the best minds

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We look forward to seeing you in Chicago!

Submit your abstract by Friday, December 1, 2017

Register and save byDecember 15, 2017

Become aMember! Join theAACR and receive adiscount on registration.

INNOVATIVECANCERSCIENCE

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A M E R I C A N A S S O C I A T I O N F O R T H E A D V A N C E M E N T O F S C I E N C E

Congratulations

to Flavio Donato, Ph.D.

Kavli Institute

Norwegian University of

Science and Technology

AAAS®andScience®are

registeredtrademarksoftheAmericanAssociationfortheAdvancementofScience,USA.Eppendorf®

andtheEppendorfBrandDesignare

registeredtrademarksofEppendorfAGGerm

any.

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reserved,includinggraphicsandim

ages.Copyright©

2017byEppendorfAG.Photo:GeirMogen,KavliInstitute

forSystemsNeuroscience.

Learn more at: www.eppendorf.com/prize

And the Winner Is...Eppendorf & Science Prize for Neurobiology

Congratulations to Flavio Donato on winning the

2017 Eppendorf & Science Prize for his work on the

driving forces that orchestrate the maturation of

circuits representing space in the brain. Dr. Donato’s

work has revealed that, during development, stellate

cells in the medial entorhinal cortex are the source of

an activity-dependent instructive signal necessary for

the maturation of those neurons that give us a sense

of where we are. This finding proves the existence of

autonomous, intrinsic drivers that guide the matura-

tion of widespread regions of cortex from deep within

the brain. Unravelling the unique contribution of these

specific neuronal populations to the function of neural

circuits will advance our understanding of how the

brain processes abstract cognitive functions.

The annual US$25,000 Eppendorf & Science Prize for

Neurobiology honors scientists, like Dr. Donato, for their

outstanding contributions to neurobiological research.

Flavio Donato is the 16th recipient of this international

award. He will be presented with the Prize at a ceremony

held during the week of the 2017 Annual Meeting of the

Society for Neuroscience in Washington DC.

You could be next to win this prize.

If you are 35 years of age or younger and currently per-

forming neurobiological research, you could be next to

win the 2018 Prize. Deadline for entries is June 15, 2018.

Neuroscience 2017

The Eppendorf & Science Prize for Neurobiology is an

international research prize of US$ 25,000. It is awarded

annually to one young scientist not older than 35 years for

the most outstanding neurobiological research based on

methods of molecular and cell biology.

Learn more about the prize at:www.eppendorf.com/prize

You could be next to win this prize.

Stop by the Eppendorf Booth #1923 and meet the 2016

Winner, Dr. Gilad Evrony. Learn more about his research on

technologies to sequence and analyze the genomes

of single cells in the human brain. Ask the Prize Jury Chair,

Dr. Peter Stern, about the prize application process and

what makes a winning paper.

Register for prize updates to receive an Eppendorf

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*Subject to prize eligibility while supplies last.

Meet & Greet

Neuroscience 2017, Washington, DC

Sunday, November 12, 2017

2:00 – 3:00 pm, Booth #1923

AAAS®andScience®are

registeredtrademarksoftheAmericanSociety

fortheAdvancementofScience,USA.Eppendorf®andtheEppendorfBrandDesignare

registeredtrademarksofEppendorfAG,Germ

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2017byEppendorfAG.KurstinRoePhotography.

Dr. Peter Stern, Science Editor & Prize Jury Chair Dr. Gilad Evrony, 2016 Prize Winner

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27 OCTOBER 2017 • VOL 358 ISSUE 6362 539 SCIENCE sciencemag.org/custom-publishing

LIFE SCIENCE TECHNOLOGIES Produced by the Science/AAAS Custom Publishing Office

EMCCD Camera Platform

Andor Technology launched its ultra-sensitive iXon Life Electron Multiplying Charge-Coupled Device (EMCCD) cam-� !"��!��� ��"�������� "�� "�� �-cence microscopy. Available in 1024 x 1024 and 512 x 512 sensor formats, back-illuminated to deliver the high-��"!��"� �!���"�!���"������� "of any microscopy camera, and deep cooled down to ñ80∞C for minimal

dark current, iXon Life provides the ultimate detector technology for single-molecule biophysics and low-light live-cell microscopy in a distinctly budget-friendly platform. iXon Life uses the lowest pos-sible excitation power while maintaining superb signal-to-noise ratio, ��"����������"����������"������"���"�����" ��!��"���"����!��"detector for single-molecule biophysics laboratories. Single-molecule experiments present researchers with the considerable challenge of �! �����"!"�������"������"�����"� ��"� �!����"�������!�"��-rescent molecules while also avoiding photobleaching. Andor iXon �����"�������"��" !���!�� "���� �� �"��������"����������! "metal-oxide semiconductor (sCMOS) detectors in this most demand-ing of light-starved application areas. Andor TechnologyFor info: +44-(28)-9023-7126

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implied. Additional information may be obtained from the manufacturer or supplier.

Automated Simultaneous PipettorThe CyBio Well vario includes an automated base that accepts dif-ferent interchangeable pipetting heads simultaneously. The heads can be changed quickly and easily either at the front or back of the instrument. The calibration is maintained after head exchanges. A working volume range of four orders of magnitude allows liquid transfers from 25 nL up to 250 µL on one platform, either with 96 or 384 disposable tips. The CyBio Well vario adapts into any screening environment and is compatible with all other accessories of the Cy-Bio Well family. The innovative CyBio Composer Software supports ������� ������������������������������������������������������Analytik JenaFor info: +49-(0)-3641-77-9400www.analytik-jena.de/en

Automated Workstations

Biomek i-Series Automated Workstations have been designed to optimize dependability and walkaway time in mid- to high-throughput labs. The bright, multiple-color, pattern-coded status light bar alerts you to the instrumentís current mode, even from across the room. Biomekís light curtain provides a key safety feature during operation and method development. An internal LED light illuminates the instrument deck for easy access and monitoring ������������������������������������������������������������������������������������������������������������� ����The large-volume, 1-mL multichannel pipetting head expedites ������������������������������������������������������Spacious, open-platform design permits access from all sides to ���������������������������������������������������������������elements (e.g., analytical devices, external storage/incubation units, and labware feeders). Onboard cameras allow live broadcast and on-error video capture to expedite response time and system diagnosis. Biomek i-Series software can interface with third-party software and all other Biomek support software.Beckman Coulter Life Sciences

For info: 800-526-3821http://biomek.beckman.com/meet-the-platform

Forensic Mitochondrial Analysis Software�%�%�'&�%&���((�%�%�%�(��(�%(��%(�&�(����%&�'���('�'�'��%(software developed exclusively for analysis of NGS mitochondrial sequencing, with applications including mass disaster and missing �%&��(�%����'����('(�%��('(����'�(�%'%(&%%'&��('��(��&%��('���&��������(��(�&���%('(�&%'���%�(��&� ��(��&(forensic and medical research mitochondrial DNA data analysis from NGS systems, such as the Illumina and Ion Torrent platforms, in an easy-to-use Windows operating system. The software aligns data to a reference and includes a unique ìmotifî alignment algorithm that automates the recommendations of the DNA Commission of the International Society for Forensic Genetics, for recognition and proper assignment of variants, motifs, and genomic insertions and deletions (INDELs) consistent with phylogenetic and forensic considerations. The software also features quick export to ��� �(!��%(��&��%'�(�"#(�&�����(�&���$(��������&'�(�"#(Population Database); user management functionality; audit trail capabilities; and synchronized comparison of multiple samples as well as customizable viewing and reporting to protect health information.SoftGenetics

For info: 888-791-1270www.softgenetics.com

����� ����������������Integrating solid-phase extraction (SPE) with all the capabilities of an automated liquid handler, the GX-Series ASPEC is Gilsonís solution ��'��$'%$��%$�$��'��%'�&��$%�'�$����$�'����� '�&�&��$'���%�$��'��&�'&%$'����$�$����$'&��'����$'��'��$%&�$�'��$'� �!"#'�����'�-%���&����'� �$�'�'&'����$'�������&������'��&���%�'�����%$�'����'automated preparative and analytical HPLC capabilities that can be used to isolate, analyze, and desalt reagent-grade oligonucleotides in one continuous run. Gilson SPE systems feature cutting-edge technology in a space-saving, modular design that can be custom-��$�'��'�$$�' �%'$�&��'�$����&�����'��$'� �!"#'�'%$&� '%����'out of the box and saves time by coming equipped with precapped cartridges. Gilson

For info: 800-445-7661www.gilson.com

DNAse Kit

��%(� !"�(�����&%%(#��(����'��(&%'�%��(��&(��%(%���%���(�����%�%(digestion of DNA along with the removal of the DNAse enzyme and divalent cations postdigestion. TURBO DNase is a recombinant, engi-�%%&%�(��&�(��(�%�� &������%'%(���'%$(�(��'�(�(���(��&%(%�-cient than wild-type DNase I in removing trace amounts of unwanted DNA prior to reverse transcription-PCR (RT-PCR). TURBO DNase binds DNA substrates sixfold more tightly than traditional DNase I, making this enzyme the tool of choice for clearing residual DNA that can generate a false positive signal in RT-PCR applications. TURBO ��'%(���(�����%('�(%��'��%&(��'�(���&%'%(��(%�%����%�%(� (two orders of magnitude. The kit includes a reagent to completely remove DNAse without phenol treatment or heating.��� �������� ��������

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Jean-Paul-Str. 12

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info@avh.de

Exzellenz verbindet –

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Reach for the stars

Profit from excellent research conditions in Germany

The Alexander von Humboldt Professorships are Germany’s way of creating a beacon effect and energising its

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researchers up to five million euros each to create new or consolidate existing internationally visible research

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www.humboldt-foundation.de

Academics of all disciplines are eligible for an Alexander

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of leading female academics.

Closing dates for nominations:

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For detailed information please visit: www.humboldt-foundation.de/ahp-en

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