DRUG DELIVERY: PRINCIPLES ANDENGINEERING

TYPE OF COURSE : New | Elective | COURSE DURATION : 12 weeks (29 Jul'19 - 18 Oct'19) EXAM DATE : 16 Nov 2019

PROF. RACHIT AGARWALDepartment of BioSystems Science and EngineeringIISc Bangalore

PRE-REQUISITES : A course in biochemistry, olecular biology, natomy is recommendedINTENDED AUDIENCE : Anyone in bachelors having completed two yearsINDUSTRIES APPLICABLE TO : All pharmaceuticals, ospitals and biotechnology industries

COURSE OUTLINE :This course introduces concepts of drug delivery to meet medical challenges. The course is designed to be modular, with each module focusing on the various aspects of drug delivery

ABOUT INSTRUCTOR : Rachit Agarwal is c

COURSE PLAN : Week : Pharmacokinetics: Bioavailability, Elimination, Therapeutic index

eek : Prodrugs, Controlled releaseWeek : Polymers: Synthesis, roperties, haracterization, rystallinity and amorphousness

eek Week : Polymer-Drug conjugates, PEGylationWeek : Diffusion controlled systems, Ficks laws, Reservoir systems, Non-erodible matrix               systems, Week : Hydrogels: Physical or chemical, ore-size calculation, n-situ crosslinkingWeek : Nano and Micro-particles: Dendrimers, Liposomes, MicellesWeek : Metal and polymeric particles, ffect of particle shape, harge and elasticityWeek : Protein Adsorption and tissue engineering, Drug delivery in tissue engineeringWeek : Implant associated infections, Route specific delivery: Oral, Subcutaneous,

Week : Vaccines, Cancer vaccines, Cell and gene delivery, Smart responsive drug delivery,                 Targeted drug delivery, Nanotoxicology and market translation

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