JOIN US FOR A POWERFUL INTERNATIONAL MEDTECH PARTNERING EVENT

Gain a 360° View of your Market, Opportunities and

Challenges

DUBLIN

REGISTER TODAyApril 16-18, 2013The Shelbourne HotelDublin, Ireland

IN3Dublin.com

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As an Early-, Mid- or Late-Stage Start-Up Seeking Investment or Partnership: Present to our audience of key global decision makers in investment, corporate business development and venture capital, and advance your company to the next level.

As an Investor: Meet the management teams and hear pitches from more than 35 carefully selected, innovative development- to commercial-stage start-ups poised to transform existing markets or create new ones.

As a Mid-Size Medical Device Company: Learn about key drivers and limiters to your growing business. Meet potential partners to help you through clinical trials and onto the market, and assess acquisition targets.

As a Large Medical Device Company: Assess a myriad of opportunities to expand your company’s portfolio and ensure a healthy pipeline in 2013 and beyond.

As a Service Provider: Gain exposure to innovators and market leaders who are seeking quality partners and outsourcing to bring their companies and products to the next level.

PROGRAM HIGHLIGHTS

These interactive sessions are designed to benefit all participants. Top business development executives and investors share their insights and perspectives, and explore the challenges currently facing the global medical device industry.

Keynote Fireside Chat: Thomas J. Fogarty, MD

Thomas J. Fogarty, MD will discuss how the medtech industry has evolved and share his practical advice on developing the right networks for your device to succeed. Dr Fogarty is an internationally recognized cardiovascular surgeon, advisor to many large companies, inventor of the balloon catheter, Founder/Co-Founder and Chairman/Board Member to over 33 businesses and research companies, has over 135 surgical patents, and is a vintner.

Partnering Medtech Innovators with Top Investors and Corporate Acquirers

PROGRAM HIGHLIGHTS (cont.)

Medtech Investing: How do VCs Assess their Potential Return-on-Investment?

Despite the dire headlines, venture capitalists are still investing in medtech start-ups, even early stages. Learn what kind of deals the VCs are doing now and in the future and explore medical device investing, financing and exit strategies.

• Alan O’Connell, Partner, Seroba Kernel Life Sciences • John E. Milad, Investment Manager, NBGI Ventures • Antoine Papiernik, Managing Partner, Sofinnova Partners • Timothy Haines, Partner, Abingworth Management• Thom Rasche, Partner, Earlybird Venture Capital• Klaus Stoeckemann, Managing Partner, Peppermint VenturePartners• David Cassak (moderator), VP of Content, Elsevier Business Intelligence• Steve Levin (moderator), Editor-in-Chief, Elsevier Business Intelligence

Strategics on Deal Priorities: Driving Growth through Different Structures

Virtually all medtech exits take place by M&A. What are the strategics looking for when acquiring? Large device executives share their insights on what they like to see from smaller venture-backed companies and how they are driving growth through M&A.

• Chad Cornell, VP of Corporate Development, Medtronic• Amir Blumenfeld, MD, MHA, Director of Discovery, Edwards Lifesciences• Townsend Goddard, Director of Business Development & Strategic Planning, Stryker• Dennis Crowley, VP of Corporate Development & Licensing, Covidien • Edward Andrle, VP of Business Development, Sorin Group• Zeev Zehavi, VP of Venture Investments, Johnson & Johnson Development• David Cassak (moderator), VP of Content, Elsevier Business Intelligence• Steve Levin (moderator), Editor-in-Chief, Elsevier Business Intelligence

“It’s a terrific forum which brings together thought leaders from across the different parts

of the ecosystem...” - Mike Carusi, General Partner, Advanced

Technology Ventures

IN³ MEDICAL DEVICE 360° DUBLIN 2013 WILL BENEFIT ALL PLAyERS IN THE DEVICE SPACE

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Start in Ireland and Take on the World: Why Ireland is the Choice Destination for Multinationals and Startups

Hosted by Enterprise-Ireland and the Irish Medical Device Association. It will give you an overview of: The Irish economy, The world class medical device and life-science sector in Ireland, and Unique range of supports

available to startups in Ireland. A panel discussion will follow with contributions from entrepreneurs who have built and sold successful companies in Ireland.

Synergies Between US and European companies in Medtech Development and Commercialization

Given the challenges in raising capital for emerging med tech opportunities and getting regulatory approval, is the US or Europe the best place to be? Or do you build on the advantages that each region offers and get the best of both? We’ll explore this subject with executives from both geographies, each of whom has taken a different approach to the issue.

• James Greene, CEO, APICA Cardiovascular• Simon Cartmell, Venture Partner, Imperial Innovations• Hanson Gifford, CEO, The Foundry• Derek young, CEO, i360 Medical

START-UP PRESENTERS *First-Time Presenter

Access Bio, Inc. - A manufacturer of rapid diagnostic tests, producing over 70 million tests annually, with a glucose-6-phosphate dehydrogenase (G6PD) defi ciency screening product that was launched in December 2012.

Aerogen, Inc.* - A global leader in aerosol drug delivery systems, and is the gold standard in nebulization throughout the healthcare continuum.

Aerolase - Develops, manufactures and markets dermatology/aesthetic lasers with unique advantages in effi cacy and safety -- particularly for darker skintones--and portability, versatility and low cost.

AltaScience* - Has developed AltaSeal®, a female sterilisation device that can be implanted hysteroscopically in a gynaecologist’s offi ce, has shown that it is easy to use and can provide immediate sterilisation.

APICA Cardiovascular, Ltd.* - A medical device company developing an Access, Stabilization and Closure (ASC™) platform technology which enables and standardizes delivery of large therapeutic devices into the beating heart without blood loss.

Calon Cardio* - Reinventing LVAD therapy for Advanced Heart Failure. The Calon MiniVAD is smaller, has a fundamentally different layout and will signifi cantly improve VAD treatment health economics.

Cardiograde, Inc. - The Nano-Pulse measures arterial elasticity and autonomic nervous system function.

Chronix Biomedical, Inc.* - Has developed a companion diagnostic for breast cancer patients undergoing neoadjuvant therapy that determines whether a patient requires surgery after chemo.

Clinical Laserthermia Systems AB - New TRANBERGCLS |Cancer Immunotherapy System is specifi cally designed for Immunostimulating Interstitial Laser Thermotherapy (imILTCLS) procedures is designed for less invasive surgical and percutaneous imILTCLS - procedures.

Expanding Orthopedics, Ltd.* - A VC backed medical device company and a US Corporation located in Israel with extensive patent portfolio around expandable device platform allowing for enhanced bone fi xation through a minimal invasive approach.

FBC Device* - Focuses on the development of new implant concepts and designs with the aim to further improve treatment of degenerated spinal disorders by optimizing functional outcome and quality of life on a long-term basis.

GlySure - Has developed a continuous intravascular glucose monitoring system to meet the $2B+ worldwide demand for implementation of Tight Glycemic Control (TGC) in the hospital Intensive Care Unit (ICU).

Humedics* - Develops a system that determines the liver functional capacity in real-time using a laser based CE-certifi ed medical device and a diagnostic drug that is labeled with the stable isotope 13C.

i360 Medical* - Focuses on improved healthcare outcomes arising from the conception, development and commercialization of new medical device technologies. The company networks with clinicians, medical professionals,

academia and engineers to source new unmet clinical needs and new ideas for medical devices.

InControl Medical, LLC* - A Women’s Health Company focusing on incontinence. InTone, an innovatively designed product, holds many patents and is designed and manufactured in the USA.

Mainstay Medical* - Developing the ReActiv8 - an active implantable stimulation device to address the huge unmet clinical need of patients with chronic non-specifi c low back pain.

Mederi Therapeutics* - Makes products that use RF energy to treat diseases of the GI tract. Mederi current product offerings are for GERD and Bowel Incontinence.

MedLumics SL* - A medical imaging company specializing in advanced optical coherence tomography (OCT) technology which integrates optical and electrical components in a compact microchip-based OCT system.

Neuravi, Ltd. - Developing a thrombectomy device to help Stroke Doctors treat their patients very quickly after stroke onset by removing the offending clots with our proprietary 3D Stent-Trap technology.

NorDocs - Has developed a non-invasive neurostimulation platform and the protocols for specifi c medical indications, beginning with nicotine and narcotic addictions.

Our Events Feature Partnering Software: All registered attendees have access to our state-of-the-art web-based software prior to the conference to pre-arrange on-site meetings with other attendees. Meet potential partners and ensure maximum return on your conference investment.

For over 13 years, IN3 Medical Device 360° has been the leading global medical device investment and partnering forum. This must-attend event brings together development- to commercial-stage device start-ups from around the world seeking funding or strategic partnership

with top-tier venture capital and strategic decision makers. The program includes presentations given by start-ups, panel discussions on fi nancing, business development, clinical/regulatory, and emerging markets, networking sessions and meet-and greets with industry experts.

The Shelbourne Dublin, A Renaissance Hotel27 St Stephen’s Green • Dublin, 2 IrelandToll Free: 353-1800-409 929353-1-6634500

A national treasure built in 1824, The Shelbourne Hotel has been magnifi cently restored while keeping its historic charm. This luxury 5-star hotel in Dublin city center overlooks St. Stephen’s Green, Europe’s grandest garden square. Ideally situated close to Dublin’s cultural and historic buildings, The Shelbourne offers a great location from which to explore Dublin city and is within strolling distance of Trinity College, numerous museums, art galleries, and Grafton Street. w

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Novate Medical* - Developing novel inferior vena cava fi lters for the prevention of pulmonary embolism (PE) in patients at high risk for venous thromboembolic events. Quanta Fluid Solutions* - A medical device company based in England that has developed a small portable home dialysis machine for use by patients.

Spinelab AG* - Developing and distributing innovative spinal treatment concepts featuring the elastic stabilization system Elaspine™, which is currently being evaluated in a European multicentre study.

Technopath* - Have developed a range of high quality calibrators, profi ciency sera and liquid stable quality controls for the clinical diagnostics market.

Vascular Flow Technologies Ltd. - innovative Spiral Laminar Flow™ technology helps to restore the body’s own natural and effi cient method of transporting blood in vessels where our prosthetic vascular grafts have been used to repair diseased veins and arteries in patients.

Veryan Medical, Ltd. - Developed and patented a three-dimensional (3D) stent technology based upon a helical shape that may be applied to a self-expanding stent platform.

Well Beingz* - Next-generation wellness program with sophisticated physical and mental health diagnostic software.

NBGI Ventures Medtronic

Abingworth Management Peppermint Venture Partners

Covidien Seroba Kernel Life Sciences

Delta Partners Sofinnova Partners

Earlybird Venture Capital Sorin Group

Fountain Healthcare Partners Stryker Corp.

Imperial Innovations Wellington Partners

Johnson & Johnson Corp.

NETWORK WITH TEAMS FROM THESE TOP STRATEGICS AND INVESTMENT FIRMS, AMONG MANy OTHERS:

DUBLIN

PLATINUM SPONSORS SILVER SPONSORS MEDIA PARTNERS

EVENT SPONSORS

April 16-18, 2013 / The Shelbourne HotelDublin, Irelandwww.in3dublin.com

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ExHIBITOR

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