eent drug study2

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Drug Drug Class. Therapeutic Actions Indications Contraindications Adverse Effect Ranitidine Brand name: Taladine, Zantac Histamine -stimulates the stomach cells to  produce acid. Anti -ulcer agents Treatment and  prevention of heartburn, acid indigestion, and sour stomach •Hypersensitivity, Cross-sensit ivity may occur; some oral liquids contain alcohol and should be avoided in patients with known intolerance. Use Cautiously in: • Renal impair- ment • Geriatric patients (more susceptible to adverse CNS reactions) • Pregnancy or Lactation • CNS Confusion, dizziness, drowsiness, hallucinations, headache • CV: Arrhythmias • GI: Altered taste, black tongue, constipation, dark stools, diarrhea, drug-induced hepatitis, nausea • GU: Decreased sperm count, impotence • ENDO: Gynecomastia • HEMAT: Agranulocytosis, Aplastic Anemia, neutropenia, thrombocytopenia • LOCAL: Pain at IM site • MISC: Hypersensitivity reactions, vasculitis

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8/6/2019 Eent Drug Study2

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Drug DrugClass.

TherapeuticActions

Indications Contraindications Adverse Effect

Ranitidine

Brand name:Taladine, Zantac

Histamine-stimulatesthestomach

cells to produce

acid.

Anti -ulcer agents

Treatment and prevention of heartburn, acidindigestion,

and sour stomach

•Hypersensitivity,

Cross-sensitivity may

occur; some oral

liquids contain alcohol

and should be avoided

in patients with known

intolerance.

Use Cautiously in:

• Renal impair- ment

• Geriatric patients

(more

susceptible to adverse

CNS reactions)

• Pregnancy or 

Lactation

• CNSConfusion, dizziness, drowsiness,hallucinations,headache

• CV:Arrhythmias

• GI:

Altered taste, black tongue,

constipation, dark stools,

diarrhea, drug-induced hepatitis, nausea

• GU:Decreased sperm count, impotence• ENDO:Gynecomastia

• HEMAT:

Agranulocytosis, Aplastic Anemia,

neutropenia,

thrombocytopenia

• LOCAL:Pain at IM site

• MISC:

Hypersensitivity reactions, vasculitis

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Tramadol

Brand name:

Rybix ODT, Ryzolt,Ultram

Analgesics(centrallyacting)

PhysiologicMechanism

• Decreased pain.

PharmacologicMechanism

• Binds to mu-opioidreceptors.

• Inhibitsreuptake of 

serotonin and

norepinephrinein the CNS.

Moderate tomoderately severe

 pain• where opioids

are

contraindicated,

including acute

intoxication with

any of the

following: alcohol,

hypnotics,

narcotics, centrally

acting analgesics,

opioids or 

 psychotropic

drugs.

• worsen central

nervous systemand respiratory

depression in these

 patients.

Body as a Whole – Asthenia, fatigue,hot flushes

Central and Peripheral NervousSystem – Dizziness, headache, tremor 

Gastrointestinal System – Abdominal pain, constipation, diarrhea, dyspepsia,flatulence, dry mouth, nausea, vomiting

Psychiatric Disorders – Anorexia,anxiety, confusion, euphoria, insomnia,nervousness, somnolence

Skin and Appendages – Pruritus, rash,increased sweating.

Selected Adverse events occurring atless than 1%: the following lists

clinically relevant adverse reactions thatoccurred with an incidence of less than

1% in ULTRACET® clinical trials.

Body as a Whole – Chest pain, rigors,syncope, withdrawal syndrome

Cardiovascular Disorders– 

Hypertension, aggravated hypertension,hypotension

Central and Peripheral Nervous

System – Ataxia, convulsions,hypertonia, migraine, aggravatedmigraine, involuntary muscle

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contractions, paresthesias, stupor,vertigo

Gastrointestinal System– Dysphagia,melena, tongue edema

Hearing and Vestibular Disorders – 

Tinnitus

Heart Rate and Rhythm Disorders – 

Arrhythmia, palpitation, tachycardia

Liver and Biliary System– Hepaticfunction abnormal

Metabolic and Nutritional Disorders

 – Weight decrease

Psychiatric Disorders – Amnesia,depersonalization, depression, drugabuse, emotional lability, hallucination,impotence, paroniria, abnormal thinking

Red Blood Cell Disorders – Anemia

Respiratory System – Dyspnea

Urinary System – Albuminuria,micturition disorder, oliguria, urinaryretention

Vision Disorders – Abnormal vision

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Ciprofloxacin brandname: Cipro

Antibacterial

Fluoroquinolone Bactericidal;

interferes withDNAreplication insusceptible

 bacteria preventing cell

reproduction.

For the treatment of infections caused bysusceptible gram-negative bacteria,including E. coli, P.

mirabilis, K. pneumoniae,Enterobacter cloacae,P. vulgaris, P.rettgeri, M. morganii,P. aeruginosa,Citrobacter freundii,

S. aureus, S.epidermidis, group D

streptococci

Contraindicated withallergy tociprofloxacin,norfloxacin or other fluoroquinolones,

 pregnancy, lactation.

Use cautiously withrenal dysfunction,seizures, tendinitis or tendon ruptureassociated withfluoroquinolone use.

CNS: Headache, dizziness, insomnia,

fatigue, somnolence, depression, blurred vision

CV: Arrhythmias, hypotension, angina

EENT: Dry eye, eye pain, keratopathy

GI: Nausea, vomiting, dry mouth,diarrhea, abdominal pain

Hematologic: Elevated BUN, AST,

ALT, serum creatinine and alkaline phosphatase; decreased WBC,neutrophil count, Hct

Other: Fever, rash

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Calciumcarbonate

Brand name: Alka-Mints, Alkets,

Alkums, Amilac-antacids

- Calcium

carbonate isused to prevent

and to treatcalcium

deficiencies.

- As a dietarysupplement wherecalcium intake may

 be inadequate:childhood,

adolescence,adulthood, pregnancy, lactation, perimenopausal and postmenopausalwomen and in theaged.

- Hypercalcemia andhypercalciuria (e.g.hyperparathyroidism,vitamin D overdosage,decalcifying tumorssuch as

 plasmocytoma, bonemetastases); severerenal disease; and incalcium loss due toimmobilization.Hypersensitivity toany of thecomponents.

-

• upset stomach• vomiting

• stomach pain•  belching• constipation

• dry mouth• increased urination• loss of appetite

• metallic taste

-

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Vitamin bcomplex

 - thiamine(B1),

riboflavin(B2),niacin(B3),

 pantothenicacid (B5),

 pyridoxine(B6), biotin(B7), folicacid or folate (B9),

cobalamin(B12)

- essential for growth,development,and a variety of other bodilyfunctions. They

 play a major role in the

activities of enzymes,

 proteins thatregulate

chemicalreactions in the

 body, whichare importantin turning foodinto energy andother neededsubstances.

-patients with chronicobstructive

 pulmonary disease

(COPD) on a regular aerosol  bronchodilator whocontinue to haveevidence of 

 bronchospasm andwho require a second

 bronchodilator 

-history of hypersensitivity tosoya lecithin or relatedfood products such assoybean and peanut.

-cardiac

-allergic reactions (Rash, Oropharyngealedema, angioedema, bronchospasm)

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CombiventBrand name:Combivent, DuoNeb

 bronchospasms

(combination of 

ipratropiumand

albuterolinhaler )

-prevent airwayspasms

-osteoarthritis, 

rheumatoid arthritis, acute pain, painfulmenstruation and

menstrual symptoms,ankylosingspondylitis and toreduce the number of colon and rectal

 polyps in patientswith familialadenomatous

 polyposis. It wasoriginally intended torelieve pain whileminimizing thegastrointestinaladverse effectsusually seen withconventional

 NSAIDs.

-with allergies tosulfonamides,

celecoxib, NSAIDS,or aspirin, significantrenal empairment;

 pregnancy (third tri),lactation

-headache, abdominal pain, dyspepsia,diarrhea, nausea, flatulence, andinsomnia.

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CelecoxibBrandname:celebrex

-analgesics

-nonsteroidalantiinflammatory drug(NSAID) thatis used to treatarthritis, pain,menstrualcramps, and

colonic polyps.Prostaglandinsare chemicalsthat are

importantcontributors to

theinflammation

of arthritis thatcauses pain,

fever , swelling

and tenderness.

- lower respiratory

tract infections,skinand skin structureinfections, urinary

tract infections, bacterial septicemia, bone and jointinfections,gynecologicinfections, intraabdominal infections(including

 peritonitis), andcentral nervoussystem infections(includingmeningitis).

- hypersensitivity toceftazidime or thecephalosporin groupof antibiotics.

- Diarrhea; headache; nausea; numbnessor tingling of skin; stomach pain;vomiting.

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CeftazidimeBrand name: Fortazand Tazicef 

-antibiotics

-Treating bacterialinfections.

DRUG DRUG CLASS THERAPEUTICACTIONS

INDICATIONS CONTRAINDICATIONS ADVERSE AFFECT

9.CeftazidimeBrand name: Fortaz

and Tazicef 

-antibiotics -Treating bacterialinfections.

- lower respiratorytract infections,skin

and skin structureinfections, urinarytract infections,

 bacterial septicemia, bone and jointinfections,gynecologicinfections, intra

- hypersensitivity toceftazidime or the

cephalosporin group of antibiotics.

- Diarrhea; headache;nausea; numbness or 

tingling of skin;stomach pain;vomiting.

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10.CelecoxibBrandname: celebrex

-analgesicsnonsteroidalantiinflammatorydrug (NSAID) that isused to treat arthritis, 

 pain, menstrualcramps, and colonic

 polyps.Prostaglandins arechemicals that areimportantcontributors to theinflammation of arthritis that causes

 pain, fever , swellingand tenderness.

abdominal infections(including

 peritonitis), andcentral nervous

system infections(including

meningitis).

-osteoarthritis ,rheumatoid arthritis,acute pain, painfulmenstruation andmenstrual

symptoms,ankylosing

spondylitis and toreduce the number 

of colon and rectal polyps in patients

with familialadenomatous

 polyposis. It wasoriginally intendedto relieve pain whileminimizing thegastrointestinaladverse effectsusually seen withconventional

-with allergies tosulfonamides, celecoxib,

 NSAIDS, or aspirin,significant renalempairment; pregnancy

(third tri), lactation

--headache,abdominal pain,dyspepsia, diarrhea, nausea, flatulence, and insomnia.

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11.CombiventBrand name:Combivent, DuoNeb

-bronchospasms(combination of ipratropium andalbuterol inhaler )

-prevent airwayspasms

 NSAIDs.

-patients withchronic obstructive

 pulmonary disease(COPD) on a regular aerosol

  bronchodilator whocontinue to haveevidence of 

 bronchospasm andwho require asecond

 bronchodilator -history of hypersensitivity to soyalecithin or related food

 products such as soybeanand peanut.

-cardiac

-allergic reactions(Rash, Oropharyngealedema, angioedema,

 bronchospasm)

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12.Vitamin bcomplex

- thiamine (B1),riboflavin (B2),niacin (B3),

 pantothenic acid(B5), pyridoxine(B6), biotin (B7),folic acid or folate(B9), cobalamin(B12)

- essential for growth,

development, and avariety of other 

 bodily functions.

They play a major role in the activities

of enzymes, proteinsthat regulate

chemical reactions inthe body, which are

important in turningfood into energy and

other neededsubstances.

- As a dietarysupplement wherecalcium intake may

 be inadequate:childhood,

adolescence,adulthood,

 pregnancy, lactation,  perimenopausal and

 postmenopausal

women and in theaged.

- Hypercalcemia andhypercalciuria (e.g.

hyperparathyroidism,vitamin D overdosage,

decalcifying tumors suchas plasmocytoma, bone

metastases); severe renaldisease; and in calciumloss due toimmobilization.Hypersensitivity to any of the components.

• upset

stomach•

vomiting• stomach pain•  belching

• constipation• dry mouth• increased

urination• loss of 

appetite• metallic taste

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13.Calciumcarbonate

Brand name: Alka-Mints, Alkets,Alkums, Amilac

-antacids

-Calcium carbonateis used to prevent

and to treat calciumdeficiencies.

- For the treatment

of infections caused by susceptible gram-negative bacteria,

including E. coli, P.mirabilis, K.

 pneumoniae,Enterobacter cloacae, P. vulgaris,P. rettgeri, M.morganii, P.aeruginosa,

Citrobacter freundii,S. aureus, S.epidermidis, groupD streptococci

- Moderate to

moderately severe

 pain

- Contraindicated withallergy to ciprofloxacin,norfloxacin or other fluoroquinolones,

 pregnancy, lactation.

Use cautiously with renaldysfunction, seizures,tendinitis or tendonrupture associated withfluoroquinolone use.

CNS: Headache,

dizziness, insomnia,fatigue, somnolence,

depression, blurredvision

CV: Arrhythmias,

hypotension, angina

EENT: Dry eye, eye pain, keratopathy

GI: Nausea,vomiting, dry mouth,diarrhea, abdominal

 pain

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15.Tramadol

Brand name:

Rybix ODT, Ryzolt,Ultram

Analgesicsnonsteroidalantiinflammatorydrug (NSAID) that isused to treat arthritis, 

 pain, menstrualcramps, and colonic

 polyps.Prostaglandins are

chemicals that areimportant

contributors to theinflammation of 

arthritis that causes pain, fever , swelling

and tenderness.

Disorders – 

Anorexia, anxiety,confusion, euphoria,insomnia,nervousness,somnolence

Skin and

Appendages – 

Pruritus, rash,increased sweating.

Selected Adverse

events occurring atless than 1%: the

following listsclinically relevant

adverse reactions thatoccurred with anincidence of less than1% in ULTRACET®

clinical trials.

Body as a Whole – 

Chest pain, rigors,syncope, withdrawal

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syndrome

Cardiovascular

Disorders– 

Hypertension,aggravatedhypertension,hypotension

Central and

Peripheral Nervous

System – Ataxia,convulsions,hypertonia, migraine,aggravated migraine,involuntary muscle

contractions, paresthesias, stupor,vertigo

Gastrointestinal

System– Dysphagia,melena, tongueedema

Hearing and

Vestibular

Disorders – Tinnitus

Heart Rate and

Rhythm Disorders – 

Arrhythmia, palpitation,

tachycardia

Liver and Biliary

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Treatment and

System– Hepaticfunction abnormal

Metabolic and

Nutritional

Disorders – Weightdecrease

Psychiatric

Disorders – 

Amnesia,depersonalization,depression, drugabuse, emotionallability, hallucination,impotence, paroniria,

abnormal thinking

Red Blood Cell

Disorders – Anemia

Respiratory System

 – Dyspnea

Urinary System – 

Albuminuria,micturition disorder,

oliguria, urinaryretention

Vision Disorders – 

Abnormal vision

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16.RanitidineBrand name:Taladine, Zantac

Histamine-stimulates the

stomach cells to produce acid.

Anti -ulcer agents prevention of heartburn, acidindigestion,and sour stomach

•Hypersensitivity, Cross-

sensitivity may occur;

some oral liquids containalcohol and should be

avoided in patients with

known intolerance.

Use Cautiously in:

• Renal impair- ment

• Geriatric patients (more

susceptible to adverse

CNS reactions)• Pregnancy or Lactation

• CNSConfusion, dizziness,

drowsiness,hallucinations,headache• CV:Arrhythmias

• GI:

Altered taste, black 

tongue, constipation,

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dark stools,

diarrhea, drug-

induced hepatitis,

nausea

• GU:Decreased spermcount, impotence• ENDO:Gynecomastia

• HEMAT:

Agranulocytosis,

Aplastic Anemia,

neutropenia,

thrombocytopenia

• LOCAL:Pain at IM site• MISC:

Hypersensitivityreactions, vasculitis

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ASSESSMENT NURSINGDIAGNOSIS

INFERENCE OBJECTIVES INTERVENTION/IMPELEMTATION

RATIONALE EVALUATION

S: “nahihirapan po siyang

magsalita” asverbalized by the

 patients relative.

O:

Impaired verbalcommunication

related to Physical barrier 

( tracheostomy,nasogastric tube)

Upper airwayobstruction

Tracheostomy,

nasogastric tubeinserted

Difficultyvocalizing words

After 4 hours of nursing

intervention the patient will be

able to:- use a form of 

communication to

get needs met andto relateeffectively with

 persons and his or her environment.

- Provide alternativemethods of 

communication, like pictures or visual

cues,gestures or 

demonstration.

 

- Place importantobjects withinreach.

-Anticipate and provide for  patient’s needs

- Providecommunication

needsor desires based

onindividual

situation or 

underlying deficit.

- This maximizes

 patient’s sense of independence.- Helpful indecreasingfrustration whendependent onothers

After 4 hours of nursing

intervention the patient able to:

- use a form of communication to

get needs met and

to relateeffectively with persons and his or 

her environment.

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- Talk directly to

 patient.

Speaking slowlyanddirectly. Use yes or 

noquestion to begin

with.

- Speak in normaltones

and avoid talkingtoo fast.Give patient ampletimeto respond.

- Encourage familymembers andvisitors to

 persist efforts to

communicate withthe

 patient.

and unable tocommunicatedesires.- It reduces

confusionor anxiety and

having

to process andrespond to largeamount of 

information at onetime.

- Patient is notnecessary hearingimpaired andraisingvoice may irritateor 

anger the patient.- It is importantfor family memberstocontinue talkingtothe patient toreduce

 patients isolation, promote

establishment of effectivecommunicationandmaintain sense of 

connectedness or  bonding with the

family.

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ASSESSMENT NURSINGDIAGNOSIS

INFERENCE OBJECTIVES INTERVENTION/IMPELEMTATION

RATIONALE EVALUATION

S: “di po xamasyadonagkikilos” as

verbalized by the patients relative.

O:

Activityintolerance relatedto Imposed

activity restriction

Insufficient physiological or  psychological

energy to endureor completerequired or desired dailyactivities

After 5 hours of nursingintervention the

 patient will beable to:- maintainsactivity levelwithincapabilities, asevidenced bynormal heart rateand blood

 pressure duringactivity, as well as

absence of shortness of 

 breath, weakness,and fatigue.

- Establishguidelines and goalsof activity with the

 patient andcaregiver.

- Assess the level of mobility and the

  physical conditionof the patient

-Assess thenutritional status of the patient

- Support patient in

doing ROMexercises at least 3

times a day.

- Note changes in

 balance/ gaitdisturbance, muscle

weakness.

- Motivation isenhanced if the

 patient

 participates ingoal setting.

- Helps inknowing thecapability of 

 patientwhich is neededin settinggoals.- Adequate energy

isneeded for activities to bedone.

- Exercise sustain

muscle strengthand ROM.

- May indicateneurological

changesassociated

with vitamin B12deficiency,

affecting patient safety or 

risk of injury.

- Promotes

After 5 hours of nursingintervention the

 patient able to:- maintainsactivity levelwithincapabilities, asevidenced bynormal heart rateand blood

 pressure duringactivity, as well asabsence of 

shortness of  breath, weakness,and fatigue.

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s:

O:- t/c malignant

Risk for infectionrelated toInadequateacquired

immunity

At increased risk for being invaded

 by pathogenicorganisms

After 3 hours of nursingintervention the

 patient will:

- Identifyinterventions

techniques to

 prevent/ reducerisk factors-Demonstrate

techniques,lifestyle changes

to promote safeenvironment

- Teach patient towash handsoften,especially

 beforetoileting,

 before meals

and before andafter administering

self-care

-Discuss to patientsthefollowing signsof infection-redness,swelling,increased pain,

or purulentdrainage on thesite and fever 

- Note risk factorsfor occurrence of infection.

- observed for localized sign of infection at

insertion sites of invasive lines,surgical incisions or wounds.- Review

environmentalfactors.

- Hand washingreduces therisks for infection

- To impart to

the patientwhen thewound

 becomeinfected andwhen to

soughtmedicalcare- to evaluate

 presence/character of infection.- to evaluate

 presence/character of infection.

- to assess if thereis

a need of avoidance

or modification of environment to

After 3 hours of nursingintervention the

 patient will now:

- Identifyinterventions

techniques to

 prevent/ reducerisk factors-Demonstrate

techniques,lifestyle changes

to promote safeenvironment

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- Monitor clientsvisitors/ caregivers

for respiratory

illnesses. Offer masks and tissues toclient/ visitors who

are coughing/sneezing.

- Instruct client intechniques to

 protect the integrityof skin, care of lesions and

 prevention of spreadof infection.

reduce incidenceof infection.- To limit

exposures, thisreduce cross

contamination

- Instruct client

in techniques to protect theintegrity of skin,care of lesionsand prevention of spread of 

infection.

ASSESSMENT NURSINGDIAGNOSIS

INFERENCE OBJECTIVES INTERVENTION/IMPELEMTATION

RATIONALE EVALUATION

S: “ Risk for  aspiration relatedto Presence of tracheostomy andtube feedings

At risk for entryof gastrointestinalsecretions,oropharyngealsecretions, or solids or fluids

After 5 hours of nursingintervention the

 patient will beable to:- Patient’s risk of 

- Assess pulmonarystatus for clinicalevidence of aspiration.Auscultate breathsounds for 

-Aspiration of small amounts canoccur withoutcoughing or sudden onset of respiratory

After 5 hours of nursingintervention the

 patient risk of aspiration isdecreased as a

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intotracheobronchial

 passages

aspiration isdecreased as aresult of ongoingassessment and

early intervention.

development of crackles and/or rhonchi.

- In patients with

endotracheal or tracheostomy tubes,monitor the

effectiveness of thecuff. Collaborate

with the respiratorytherapist, as needed,to determine cuff 

 pressure.- Keep suction setupavailable (in both

hospital and homesettings) and use asneeded.- Notify the

 physician or other health care provider immediately of noted decrease incough and/or gagreflexes or difficultyin swallowing.

- Provide oral careafter meals.

-

distress,especially in

 patients withdecreased levels

of consciousness.- An ineffective

cuff can increase

the risk of aspiration.

- This is necessaryto maintain a

 patent airway.

- Earlyintervention

 protects the patient’s airwayand preventsaspiration.

- This removesresiduals and

reduces pocketingof food that can

 be later aspirated.-

result of ongoingassessment andearly intervention.

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