Effects of tofacitinib monotherapy on patient-reported outcomes in a

randomized Phase 3 study of patients with active rheumatoid arthritis and

inadequate responses to DMARDs

Vibeke Strand, Joel Kremer, Gene Wallenstein, Keith S Kanik, Carol Connell, David

Gruben, Samuel H Zwillich, Roy Fleischmann

Additional file 1: Table S1. Ethical review boards and study centers

Study Center Institutional Review Board or Ethics Committee

CEPIC - Centro Paulista deInvestigacao Clinica e ServicosMedicos LtdaRua Moreira e Costa 342Sao Paulo, SP 04266-010BRAZIL

Hospital HeliopolisComite de Etica em PesquisaRua Conego Xavier, 276. 10. andarSacomaSao Paulo, SP 04231-030BRAZIL

CIP - Centro Internacional dePesquisasRua 9 B, 129 - 3 andarSetor OesteGoiania, GO 74110-120BRAZIL

Comite de Etica em Pesquisa doHospital Geral de Goiania -CEPHGGAvenida Anhhaguera, 6479 - SetorOesteGoiania, GO 74110-010BRAZIL

Hospital de Clinicas de PortoAlegreServico de ReumatologiaRua Ramiro Barcelos, 2350- 6ºandar - sala 645 ABom FimPorto Alegre, RS 90035-903BRAZIL

Comite de Etica em Pesquisa emSeres Humanos do Hospital deClinicas de Porto Alegre- HCPARua Ramiro Barcelos 2350, 2 andarBom FimPorto Alegre, RS 90035-903BRAZIL

Hospital de Clinicas de PortoAlegreGrupo de PesquisaRua Ramiro Barcelos 2350 2andarsala 2202Porto Alegre, RS 90035-003

BRAZILCentro de Estudos em TerapiasInovadorasRua Padre Camargo, 241Alto da GloriaCuritiba, PR 80060-240BRAZIL

Comitê de Ética em Pesquisa emSeres Humanos do Hospital deClínicas - UFPRRua General Carneiro, 181Curitiba, PR 80060-900BRAZIL

CCBR BrasilCentro de Pesquisas e AnalisesClinicas Ltda.Rua Mena Barreto, 33Rio de Janeiro, RJ 22271-100BRAZIL

Comite de Etica em Pesquisa doHospital Pro Cardiaco Pronto SocorroCardiologico/PROCEPRua Dona Mariana, 219Rio de Janeiro, RJ 22280-000BRAZIL

Hospital Sao Lucas da PUCRSAv. Ipiranga, 6690 - 4o andarPorto Alegre, RS 90610-000BRAZIL

Comite de Etica em Pesquisa daPontificia Universidade Catolica doRio Grande do SulAv. ipiranga 6690-Conj.314 -3 andarJardim BotanicoPorto Alegre, RS 90610-000BRAZIL

IMA Brasil - Instituto deMedicina AvancadaPraca Americo Jacomino, 55Vila MadalenaSao Paulo, SP 05437-010BRAZIL

Comite de Etica em Pesquisa doInstituto de Infectologia Emilio RibasAv. Dr. Arnaldo, 165Sao Paulo, SP 01246-900BRAZIL

MBAL na VoennomeditsinskaAkademia - SofiaKlinika po Revmatologia iKardiologiaMMA HAT SofiaUl. "Georgi Sofiyski" 3Sofia, 1606BULGARIA

Ethic Committee for MulticenterTrialsEtichna komisiya za mnogocentroviizpitvaniyaul. "Damyan Gruev" 8Sofia, 1303BULGARIAKomisiya po etika pri MBAL naVoennomeditsinska Akademia -Sofia/Ethics Commettee at MMAHAT-SofiaMMA HAT-SofiaUl. Georgi Sofiyski3Sofia, 1606BULGARIA

DKTs "Sveta Anna" SofiaKonsultativen Kabinet poRevmatologiaDiagnostic Consultative Center"Sveta Anna" SofiaUl. "Dimitar Mollov" 1

Ethic Committee for MulticenterTrialsEtichna komisiya za mnogocentroviizpitvaniyaul. "Damyan Gruev" 8Sofia, 1303

Sofia, 1709BULGARIA

BULGARIAKomisiya po etika pri DKTs"Sv.Anna"/ Ethics Committee at DCC"Sv. Anna"DKTs "Sveta Anna"Diagnostic Consultative Center"Sveta Anna"Ul. Dimitar Mollov 1Sofia, 1709BULGARIA

MBAL "Sveti Ivan Rilski" SofiaKlinika po RevmatologiaMHAT "Sveti Ivan Rilski"Ul. "Urvich" 13Sofia, 1612BULGARIA

Ethic Committee for MulticenterTrialsEtichna komisiya za mnogocentroviizpitvaniyaul. "Damyan Gruev" 8Sofia, 1303BULGARIA

UMBAL "D-r Georgi Stranski"PlevenKlinika po Kardiologia iRevmatologiaMHAT "Dr. Georgi Stranski"PlevenUl. "Georgi Kochev" 8APleven, 5800BULGARIA

Ethic Committee for MulticenterTrialsEtichna komisiya za mnogocentroviizpitvaniyaul. "Damyan Gruev" 8Sofia, 1303BULGARIAKomisiya po etika pri UMBAL"D-rGeorgi Stranski"/ Ethics Committeeat MHAT "Dr. Georgi Stranski"UMBAL"D-r Georgi Stranski"PlevenMHAT "Dr. Georgi Stranski" PlevenUl. Georgi Kochev8APleven, 5800BULGARIA

MBAL "Kaspela" Plovdiv,Otdelenie po revmatologiaMHAT "Kaspela" Plovdivul. Sofiya64Plovdiv, 4002BULGARIA

Ethic Committee for MulticenterTrialsEtichna komisiya za mnogocentroviizpitvaniyaul. "Damyan Gruev" 8Sofia, 1303BULGARIA

Komisiya po etika kam MBAL"Kaspela"/ Ethics committee atMHAT "Kaspela"MBAL 'Kaspela' PlovdivMHAT 'Kaspela' PlovdivUl. Sofiya 64Plovdiv, 4002

BULGARIAMBAL - PlovdivRevmatologichno OtdelenieMHAT - Plovdivbul. "Bulgaria" 234Plovdiv, 4000BULGARIA

Ethic Committee for MulticenterTrialsEtichna komisiya za mnogocentroviizpitvaniyaul. "Damyan Gruev" 8Sofia, 1303BULGARIAKomisiya po etika pri MBALPlovdiv/Ethics Committee at MHATPlovdivMBAL-PlovdivMHAT-Plovdivbul. Bulgaria 234Plovdiv, 4000BULGARIA

Consulta Privada Dra. MartaAlisteGuardia Vieja 255, Oficina 1409ProvidenciaSantiago, RM 7510186CHILE

Comite Etico CientificoServicio de Salud MetropolitanoOrienteAv. Salvador 364Providencia, Santiago, RM 7500922CHILE

Centro de Diagnostico yTratamiento San Borja ArriaranSeccion ReumatologiaAmazonas 619Santiago, RM 8360156CHILE

Comite Etico CientificoServicio de Salud MetropolitanoOrienteAv. Salvador 364Providencia, Santiago, RM 7500922CHILE

Clínica Santa María, SecciónReumatologíaFernando Manterola 0540Providencia, Santiago, RM7530206CHILE

Comite de EticaClinica Santa MariaAvenida Santa Maria 0410Santiago,CHILEComite Etico CientificoServicio de Salud MetropolitanoOrienteAv. Salvador 364Providencia, Santiago, RM 7500922CHILE

SERVIMED E.UCalle 51# 34-17 Consultorio208-208A Centro ComercialCabecera. Etapa IBucaramanga, SantanderCOLOMBIA

Comite de ética en Investigación deServimed E.UCalle 51 No. 34-17. Centro comercialCabecera Etapa I.Bucaramanga, SantanderCOLOMBIA

Centro de Reumatologia yOrtopediaCra 49 C No 82-125Barranquilla,

Comité de etica independiente centrode reumatologia y ortopediaCr. 49C No. 82-120Barranquilla, Atlantico 0000

COLOMBIA COLOMBIARevmatologicka ambulancePetra Rezka 3Praha 4, 140 00CZECH REPUBLIC

Eticka komise IKEM a FTNsPVidenska 800Praha 4 Krc, 140 59CZECH REPUBLIC

Revmatologicka ambulanceNuselska poliklinikaTaborska 57Praha 4, 140 00CZECH REPUBLIC

Eticka komise IKEM a FTNsPVidenska 800Praha 4 Krc, 140 59CZECH REPUBLIC

L.K.N. Arthrocentrum, s.r.o.Revmatologicka ambulanceNa Valech 1Hlucin, 748 01CZECH REPUBLIC

Eticka komise pri Fak. Thomayerovenemocnici a IKEMVidenska 800Praha 4, 140 59CZECH REPUBLIC

PV-Medical s.r.o.Revmatologicka ambulancePadelky I/3645Zlin, 760 01CZECH REPUBLIC

Eticka komise IKEM a FTNsPVidenska 800Praha 4 Krc, 140 59CZECH REPUBLIC

ARTHROMED, s. r. o.Revmatologicka ambulanceRokycanova 2798Pardubice, 530 02CZECH REPUBLIC

Eticka komise IKEM a FTNsPVidenska 800Praha 4 Krc, 140 59CZECH REPUBLIC

Revmatologicky ustavNa Slupi 4Praha 2, 128 50CZECH REPUBLIC

Eticka komiseRevmatologicky ustavNa Slupi 4Praha 2, 128 50CZECH REPUBLICEticka komise IKEM a FTNsPVidenska 800Praha 4 Krc, 140 59CZECH REPUBLIC

FN Brno, Internihematoonkologická klinikaRevmatologicka ambulanceJihlavska 20Brno, 625 00CZECH REPUBLIC

Eticka komise FN BrnoJihlavská 20Brno, 625 00CZECH REPUBLICEticka komise IKEM a FTNsPVidenska 800Praha 4 Krc, 140 59CZECH REPUBLIC

RevmatologiePod Holym vrchem 349Ceska Lipa, 470 01CZECH REPUBLIC

Eticka komise IKEM a FTNsPVidenska 800Praha 4 Krc, 140 59CZECH REPUBLIC

Fakultni Thomayerovanemocnice s poliklinikou

Eticka komise IKEM a FTNsPVidenska 800

Revmatologicke a rehabilitacnioddeleniVidenska 800Praha 4, 140 59CZECH REPUBLIC

Praha 4 Krc, 140 59CZECH REPUBLIC

Latin American ResearchAvenida Maximo Gomez #60,suite 201, plaza paseo del treatroSanto Domingo, Santo Domingo00000DOMINICAN REPUBLIC

CONABIOSUniversidad Católica Santo DomingoCalle Santo Domingo No3, Ens. LaJuliaSanto Domingo, Santo Domingo2733DOMINICAN REPUBLIC

Universitaetsklinik Leipzig,Klinik fuer Gastroenterologie undRheumatologie, SektionRheumatologieLiebigstr. 20Leipzig, 04103GERMANY

Ethik-Kommission an derMedizinischen Fakultaet derUniversitaet LeipzigHaertelstrasse 16-18Leipzig, 04107GERMANY

Schlosspark-Klinik, InnereMedizin II, RheumatologieHeubnerweg 2Berlin, 14059GERMANYSchoen Klinik Hamburg - Eilbek,Abt. Rheumatologie und Klin.ImmunologieDehnhaide 120Hamburg, 22081GERMANYKlinikum der UniversitaetMuenchen, Campus InnenstadtPettenkoferstr. 8aMuenchen, 80336GERMANYArztpraxis, Internist -RheumatologieKontumazgarten 4Nuernberg, 90429GERMANYFAE Innere Medizin /RheumatologieLudwig-Wucherer-Str. 10Halle, 06108GERMANYSt. John's Medical CollegeHospital

Institutional Ethical Review BoardSt. John's Medical College and

Sarjapur RoadBangalore, Karnataka 560 034INDIA

HospitalSarjapur RoadBangalore, Karnataka 560 034INDIA

Bowring and Lady CurzonHospitalsShivaji NagarBangalore, Karnataka 560 001INDIA

Ethical Committee, BangaloreMedical College & Research InstituteK.R. Road,Fort,Bangalore, Karnataka 560 002INDIA

Chanre Rheumatology &Immunology Centre & Research#149, 15th Main NHCLWater Tank Road4th Block, 3rd Stage,BasaveswaranagarBangalore, Karnataka 560 079INDIA

Institutional Ethical CommitteeChanre Rheumatology &Immunology Centre & Research#149, 15th Main NHCL, Water TankRoad, 4th Block, 3rd StageBasaveswaranagarBangalore, Karnataka 560 079INDIA

Jehangir Clinical DevelopmentCentre Pvt. Ltd.Jehangir Hospital32, Sassoon RoadPune, Maharashtra 411 001INDIA

Hirabai Cowasji Jehangir MedicalResearch Institute and JehangirClinical Development CenterEthics CommitteeJehangir Hospital,32, Sassoon Road,Pune, Maharashtra 411 001INDIA

Krishna Institute of MedicalSciences Ltd1-8-31/1Minister RoadSecunderabad, Andra Pradesh500 003INDIA

Institutional Ethics CommitteeKrishna Institute of Medical SciencesLtd.1-8-31/1, Minister RoadSecunderabad, Andra Pradesh500003INDIA

Arthritis Research and CareFoundationCentre for Rheumatic DiseasesNo. 11, Hermes Elegance1988, Convent Street CampPune, Maharashtra 411 001INDIA

CRD Ethics Committee11, Hermes Elegance1988, Convent Street CampPune, Maharashtra 411 001INDIA

Shalby HospitalsOpp. Karnavati ClubS.G. RoadP.O. Ambawadi VistarAhmedabad, Gujarat 380 015INDIA

Ethics Committee Shalby HospitalsShalby HospitalsOpp. Karnavati Club,S. G. Road, P. O. Ambawadi Vistar,Ahmedabad, Gujarat 380 015INDIA

Kasturba Medical CollegeHospitalAttavar

Manipal University Ethics CimmitteeMadhav NagarManipal, karnataka 576 104

Mangalore, Karnataka 575 001INDIA

INDIA

Father Muller Medical CollegeFr. Muller Road,KankanadyMangalore, Karnataka 575002INDIA

Institutional Ethics CommitteeFather Muller Medical CollegeFather Muller RoadKankanadyMangalore, Karnataka 575 002INDIA

Sri Deepti Rheumatology Centre6-2-45/8,A.C.Guards,Hyderabad, Andhra Pradesh 500004INDIA

Ethics CommitteeSri Deepti Rheumatology Centre6-2-45/8,A. C. Guards,Hyderabad, Andhra Pradesh 500 004INDIA

Mahavir Hospital & ResearchCenter10-1-1, Bhagwan Mahavir MargA.C. GuardsHyderabad, Andhra Pradesh 500004INDIA

Institutional Ethical Committee forBio Medical ResearchBhagwan Mahavir Medical ResearchCenter, Mahavir Hospital &Research Center,10-1-1, Bhagwan Mahavir Marg,A.C. Guards,Hyderabad, Andhra Pradesh 500 004INDIA

Sarawak General HospitalJalan HospitalKuching, Sarawak 93586MALAYSIA

Medical Research & EthicsCommitteeMinistry of Health, c/o NIHSecretariat, Institute for HealthManagementJalan Rumah SakitBangsarKuala Lumpur, 59000MALAYSIA

Queen Elizabeth HospitalKota Kinabalu, Sabah 88586MALAYSIAHospital PutrajayaFederal GovernmentAdministration CentrePresint 7Putrajaya, Wilayah Persekutuan62250MALAYSIASunway Medical CentreNo. 5, Jalan Lagoon SelatanBandar SunwayPetaling Jaya, Selangor DarulEhsan 46150MALAYSIAHospital Christus Muguerza delParqueCalle 14 1610 A Colonia CentroChihuahua, Chihuahua 31000

Comite de Etica e Investigacion delHospital Christus Muguerza delParqueCalle Dr. Pedro Leal Rodriguez y de

MEXICO la LlaveChihuahua, Chihuahua 31000MEXICO

Hospital Universitario JoseEleuterio GonzalezGonzalitos 235 NorteColonia Mitras CentroMonterrey, Nuevo Leon 64020MEXICO

Comite de Etica Facultad deMedicina de la UANL y HospitalUniversitario Dr. Jose EleuterioGonzalezAv. Francisco I Madero Pte s/n y Dr.E Aguirre PequenoCol. Mitras CentroMonterrey, Nuevo Leon 64460MEXICO

Unidad de Investigacion enEnfermedades CronicoDegenerativasColomos 2292Colonia ProvidenciaGuadalajara, Jalisco 44620MEXICO

Comite de Bioetica de la Unidad deInvestigacion en EnfermedadesCronico-DegenerativasColomos 2292Col. ProvidenciaGuadalajara, Jalisco 44620MEXICO

Centro de Investigacion delNoroeste SCBoulevard Sanchez Taboada9250 Interior 28Zona RioTijuana, Baja California 22010MEXICO

Comision de Investigacion y EticaCentro Medico NovaAvenida Guadalupe Victoria 9308Zona RioTijuana, Baja California 22010MEXICO

University of Santo TomasHospital6th Floor Hospital ResearchCenterClinical Division BuildingEspana StreetManila, Phlippines 1008PHILIPPINES

Institutional Review Board3rd Floor, Clinical Division BuildingUniversity of Sto. Tomas HospitalEspana Blvd.Manila, 1008PHILIPPINES

University of Perpetual HelpRizal Dalta Medical Center7th FloorResearch RoomAlabang-Zapote Road, PamplonaLas Piñas City, 1742PHILIPPINES

Institutional Ethics Review BoardInstitutional Ethics Review BoardUniversity of Perpetual Help System-DALTA 7th Floor Research RoomAlabang-Zapote RoadLas Piñas City, 1742PHILIPPINES

De La Salle Health SciencesCampus- Clinical EpidemiologyUnit2nd Floor Clinical Trial Room#2

DLS Institutional Review BoardRoom 6301De La Salle Angelo King MedicalResearch CenterCongressional Avenue

The Angelo King MedicalResearch CenterCongressional AvenueDasmarinasCavite, Phlippines 4114PHILIPPINES

Dasmariñas, Cavite 4114PHILIPPINES

Southern Philippines MedicalCenterSection of RheumatologyDepartment of Internal MedicineBajada, Davao City, Phlippines8000PHILIPPINES

Ethics CommitteeSouthern Philippines Medical CenterBajada, Davao City, 8000PHILIPPINES

Lecznica Specjalistow, CentrumMedyczne "Osteomed" NZOZAl. Krakowska 110/114Warszawa, 02-256POLAND

Komisja Bioetyczna przy OkregowejIzbie Lekarskiej w Warszawieul. Pulawska 18Warszawa, 02-512POLAND

"SYNEXUS SCM" Sp. z o.o.ul. Swobodna 8aWroclaw, 50-088POLANDState Educational Institution ofHigher professional educationSmolensk State MedicalAcademyRoszdrav, Clinical ResearchCentre of diagnostic medicineand drugsKrupskoy str., 28Smolensk, 214019RUSSIAN FEDERATION

Ethics Committee at the FederalService on Surveillance in Healthcareand Social Development8, str. 2, Petrovskij bulvarMoscow, 127051RUSSIAN FEDERATIONIndependent Ethics Committee ofState Educational Institution of HighProfessional Education"Smolensk State Medical Academyof Federal Agency of Healthcare andSocial Development"28, ul. Krupskoj, 21401927, pr. GagarinaSmolensk, 214018RUSSIAN FEDERATION

Republican Hospital n. a.V.A.BaranovPirogova str., 3Petrozavodsk, 185019RUSSIAN FEDERATION

Ethics Committee at the FederalService on Surveillance in Healthcareand Social Development8, str. 2, Petrovskij bulvarMoscow, 127051RUSSIAN FEDERATION

City Clinical Hospital # 8, Deptof Cardiology and FunctionalDiagnostics

Central Ethics Committee Ministryof Health of Ukraine5, Narodnogo Opolchennya Str.

266g, Saltivske ShosseKharkiv, 61178UKRAINE

Kyiv, 03680UKRAINECommittee for Ethics Issues of CityClinical Hospital #8266g, Saltivske ShosseKharkiv, 61178UKRAINE

Vinnitsa Regional ClinicalHospital n.a. Pirogov, Dept ofInternal Medicine #1 of VinnitsaNMU46 Pirogova StreetVinnitsa, 21018UKRAINE

Bioethics Committee of VinnitsaRegional Clinical Hospital n.a.Pirogov46 Pirogova StreetVinnitsa, 21018UKRAINE

Central Ethics Committee Ministryof Health of Ukraine5, Narodnogo Opolchennya Str.Kyiv, 03680UKRAINE

Institute of Gerontology,Department of ClinicalPhysiology and Pathology ofMusculoskeletal System67 Vyshgorodska StreetKyiv, 04114UKRAINE

Central Ethics Committee Ministryof Health of Ukraine5, Narodnogo Opolchennya Str.Kyiv, 03680UKRAINE

Committee for Ethics Issues ofInstitute of Gerontology67, Vyshgorodska StreetKyiv, 04114UKRAINE

Municipal City Clinical Hospital#4Department of Rheumatology3 Sventsitskogo StreetLviv, 79011UKRAINE

Central Ethics Committee Ministryof Health of Ukraine5, Narodnogo Opolchennya Str.Kyiv, 03680UKRAINE

Committee for Ethics Issues ofMunicipal City Clinical Hospital #43 Sventsitskogo StrLviv, 79011UKRAINE

Republican Clinical HospitalDept of Internal Medicine #2 ofSI "Crimean State MedicalUniversity n.a. S.I.Georgiyevskyj"69, Kyivska StreetSimferopol, Crimea, 95017UKRAINE

Central Ethics Committee Ministryof Health of Ukraine5, Narodnogo Opolchennya Str.Kyiv, 03680UKRAINE

Committee for Ethics Issues ofRepublican Clinical Hospital

69, Kyivska StreetSimferopol, Crimea 95017UKRAINE

Clinical Research Center ofReading, LLP2760 Century BoulevardWyomissing, PA 19610UNITED STATES

Quorum Institutional Review BoardSuite 10001601 Fifth AvenueSeattle, WA 98101UNITED STATES

Clinical Research Center of CapeCod, Inc.131 Attucks LaneHyannis, MA 02601UNITED STATESEast Penn RheumatologyAssociates, PCSuite 501 & 601701 Ostrum StreetBethlehem, PA 18015UNITED STATESFlorida Medical ClinicClinical Research Division38135 Market SquareZephyr Hills, FL 33542UNITED STATESTampa Medical Group, PASuite 3034700 North Habana AvenueTampa, FL 33614UNITED STATESSTAT Research, Inc.West Medical Plaza - Suite 230One Elizabeth PlaceDayton, OH 45417UNITED STATESArthritis Clinic & Carolina Bone& Joint, PA10460 Park RoadCharlotte, NC 28210UNITED STATESMountain State Clinical ResearchSuite 303A300 Davisson Run RoadClarksburg, WV 26301UNITED STATESUnited Hospital CenterX-ray and ECG OnlySuite 107

300 Davisson Run RoadClarksburg, WV 26301UNITED STATESAltoona Center for ClinicalResearch175 Meadowbrook LaneDuncansville, PA 16635UNITED STATESInvestigational Drug ServiceDrug Shipment Only747 BroadwaySeattle, WA 98122UNITED STATESSeattle Rheumatology AssociatesSuite 10001101 MadisonSeattle, WA 98104UNITED STATESSwedish Medical Center747 BroadwaySeattle, WA 98122UNITED STATESSouthwest Rheumatology, PASuite 61518601 LBJ FreewayMesquite, TX 75150UNITED STATESLovelace Scientific ResourcesSuite C411 Commercial CourtVenice, FL 34292UNITED STATESVenice Arthritis CenterSuite D411 Commercial CourtVenice, FL 34292UNITED STATESMetroplex Clinical ResearchCenterSuite 8108144 Walnut Hill LaneDallas, TX 75231UNITED STATESAAIR Research CenterSuite 305300 Meridian CentreRochester, NY 14618UNITED STATESThe Center for Rheumatology,

LLPSuite 1011367 Washington AvenueAlbany, NY 12206UNITED STATESJacksonville Center for ClinicalResearchSuite 14085 University Boulevard SouthJacksonville, FL 32216UNITED STATESArthrocare, Arthritis Care andResearch PCSuite 2003921 East Baseline RoadGilbert, AZ 85234UNITED STATESRheumatology Associates ofNorth Jersey1415 Queen Anne RoadTeaneck, NJ 07666UNITED STATESBoice-Willis Clinic, PASuite 320901 North Winstead AvenueRocky Mount, NC 27804UNITED STATESPiedmont Arthritis Clinic, PASuite 4003 St. Francis DriveGreenville, SC 29601UNITED STATESLovelace Scientific ResourcesSuite 5605741 Bee Ridge RoadSarasota, FL 34233UNITED STATESThe Arthritis Specialty CentreSuite 5505741 Bee Ridge RoadSarasota, FL 34233UNITED STATESRockford Orthopedic Associates,Ltd.324 Roxbury RoadRockford, IL 61107UNITED STATESThe Arthritis and Osteoporosis

Center of Maryland71 Thomas Johnson DriveFrederick, MD 21702UNITED STATESCarolina Health SpecialistsSuite 4945 82nd ParkwayMyrtle Beach, SC 29572UNITED STATESCatalina Pointe Clinical ResearchSuite 1007520 North Oracle RoadTucson, AZ 85704UNITED STATESSt. Joseph's Mercy Clinic100 McGowan CourtHot Springs, AR 71913UNITED STATES

St. Joseph's Mercy Health CenterIRB100 McAuley CourtHot Springs, AR 71903UNITED STATES

El Monte Mall - Suite 2010652 Avenue Munoz RiveraSan Juan, PR 00918UNITED STATES

Quorum Institutional Review BoardSuite 10001601 Fifth AvenueSeattle, WA 98101UNITED STATES

Baylor Research InstituteArthritis Care and ResearchCenterSuite 5509900 North Central ExpresswayDallas, TX 75231UNITED STATES

Baylor Research InstituteInstitutional Review BoardWhite/Blue/RedSuite 5013310 Live OakDallas, TX 75204UNITED STATES

Trinity Health Center - MedicalArts400 Burdick Expressway EastMinot, ND 58701UNITED STATES

Trinity IRBInstitutional Review BoardOne Burdick Expressway WestMinot, ND 58701UNITED STATES

Borgess Research InstituteSuites 003 and 0041717 Shaffer StreetKalamazoo, MI 49048UNITED STATES

Quorum Institutional Review BoardSuite 10001601 Fifth AvenueSeattle, WA 98101UNITED STATES

Borgess RheumatologySuite 1241717 Shaffer StreetKalamazoo, MI 49048UNITED STATESBrookview Hills InternalMedicine

Suite 2073333 Brookview Hills BoulevardWinston-Salem, NC 27103UNITED STATESPiedmont Medical ResearchAssociatesSuite 3061901 South Hawthorne RoadWinston-Salem, NC 27103UNITED STATESPreferred Pain ManagementSuite C245 Charlois BoulevardWinston-Salem, NC 27103UNITED STATESSouthern Tier Arthritis andRheumatism415 North 8th StreetOlean, NY 14760UNITED STATES