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Acute antioxidant pre-treatment attenuates endothelial microparticle release after decompression
Bryna C R Chrismas, Adrian W Midgley, Lee Taylor, Rebecca V Vince, Gerard Laden and Leigh A Madden
Ballham A, Allen MJ. Air embolism in a sports diver. 1 Br J Sports Med. 1983;17:7-9.Brubakk AO, Peterson R, Grip A, Holand B, Onarheim J, 2Segadal K, et al. Gas-bubbles in the circulation of divers after ascending excursions from 300 to 250 msw. J Appl Physiol.1986;60:45-51.Barratt DM, Harch PG, Van Meter K. Decompression illness 3in divers: a review of the literature. Neurologist. 2002;8:186-202.Bakovic D, Glavas D, Palada I, Breskovic T, Fabijanic D, 4Obad A, et al. High-grade bubbles in left and right heart in an asymptomatic diver at rest after surfacing. Aviat Space Environ Med. 2008;79:626-8.Nossum V, Koteng S, Brubakk AO. Endothelial damage by 5bubbles in the pulmonary artery of the pig. Undersea Hyperb Med. 1999;26:1-8.Brubakk AO, Duplancic D, Valic Z, Palada I, Obad A, Bakovic 6D, et al. A single air dive reduces arterial endothelial function in man. J Physiol. 2005;566:901-6.Benedetti S, Lamorgese A, Piersantelli M, Pagliarani 7S, Benvenuti F, Canestrari F, et al. Oxidative stress and antioxidant status in patients undergoing prolonged exposure to hyperbaric oxygen. Clin Biochem. 2004;37:312-7.Madden LA, Chrismas BC, Mellor D, Vince RV, Midgley 8AW, McNaughton LR, et al. Endothelial function and stress response after simulated dives to 18 msw breathing air or oxygen. Aviat Space Environ Med. 2010;81:41-5.Vince RV, McNaughton LR, Taylor L, Midgley AW, Laden 9G, Madden LA. Release of VCAM-1 associated endothelial microparticles following simulated SCUBA dives. Eur J Appl Physiol. 2008;105:507-13.Wadsworth RM. Oxidative stress and the endothelium. 10 Exper Physiol. 2008;93:155-7.Butler BD, Little T, Cogan V, Powell M. Hyperbaric oxygen 11
Undersea Hyperb Med. 2006;33:407-17.Dujic E, Duplanc D, Marinovic-Terzic I, Bakovic D, Ivancev 12V, Valic Z, et al. Aerobic exercise before diving reduces venous gas bubble formation in humans. J Physiol. 2004;555:637-42.
13scuba diving. Exercise Sport Sci Rev. 2008;36:38-42.Blatteau JE, Gempp E, Balestra C, Mets T, Germonpré P. 14Predive sauna and venous gas bubbles upon decompression from 400 kPa. Aviat Space Environ Med. 2008;79:1100-5.Obad A, Valic Z, Palada I, Brubakk AO, Modun D, Dujic Z. 15Antioxidant pretreatment and reduced arterial endothelial dysfunction after diving. Aviat Space Environ Med.2007;78:1114-20.Obad A, Palada I, Valic Z, Ivancev V, Bakovic D, Brubakk 16AO, et al. The effects of acute oral antioxidants on diving-
induced alterations in human cardiovascular function. JPhysiol. 2007;578:859-70.Thomas SR, Witting PK, Drummond GR. Redox control of 17endothelial function and dysfunction: molecular mechanisms and therapeutic opportunities. Antiox Redox Signal.2008;10:1713-65.Angdin M, Settergren G, Starkopf J, Zilmer M, Zilmer K, 18Vaage J. Protective effect of antioxidants on pulmonary endothelial function after cardiopulmonary bypass. JCardiothorac Vasc Anesth. 2003;17:314-20.Pratico D. Antioxidants and endothelium protection. 19Atherosclerosis. 2005;181:215-24.Pablos MI, Reiter RJ, Chuang JR, Ortiz GG, Guerrero JM, 20Sewerynek E, et al. Acutely administered melatonin reduces oxidative damage in lung and brain induced by hyperbaric oxygen. J Appl Physiol. 1997;83:354-8.Goldfarb AH, McIntosh MK, Boyer BT, Fatouros J. Vitamin 21E effects on indexes of lipid peroxidation in muscle from dhea treated and exercised rats. J Appl Physiol. 1994;76:1630-5.Bader N, Bosy-Westphal A, Koch A, Rimbach G, Weirnann 22A, Poulson HE, et al. Effect of hyperbaric oxygen and vitamin C and E supplementation on biomarkers of oxidative stress in healthy men. Br. J Nutr. 2007;98:826-33.Madden LA, Vince RV, Sandstrom M, Taylor L, McNaughton 23L, Laden G. Microparticle associated vascular adhesion molecule-1 and tissue factor follow a circadian rhythm in healthy human subjects. Thromb Haemost 2008;99(5):909-15.Mak S, Egri Z, Tanna G, Colman R, Newton GE. Vitamin C 24prevents hyperoxia-mediated vasoconstriction and impairment of endothelium-dependent vasodilation. Am J Physiol-Heart Circulatory Physiol. 2002;282:H2414-21.Eskurza I, Monahan KD, Robinson JA, Seals DR. Effect of 25
with sedentary and physically active human ageing. J Physiol.2004;556:315-24.
Gokce N, Keaney JF, Frei B, Holbrook M, Olesiak M, 26Zachariah BJ, et al. Long-term ascorbic acid administration reverses endothelial vasomotor dysfunction in patients with coronary artery disease. Circulation. 1999;99:3234-40.Barak M, Katz Y. Microbubbles - pathophysiology and clinical 27implications. Chest. 2005;128:2918-32.Madden LA, Laden G. Gas bubbles may not be the underlying 28cause of decompression illness – the at-depth endothelial dysfunction hypothesis. Med Hypoth. 2009;72:389-92.
‘Sea legs’: sharpened Romberg test after three days on a live-aboard dive boatClinton R Gibbs, Katherine H Commons, Lawrence H Brown and Denise F Blake
Malignant otitis externa: experience with hyperbaric oxygen therapyAlex Saxby, Michael Barakate, Thomas Kertesz, Joanne James and Michael Bennett
Patient Age/sex Diabetes Cranial Pathogen Admission HBOT HBOT Outcome Follow up neuropathy (days) (number) problem (months)
1 75 M Yes No Bacteroides 53 29 Ongoing otorrhoea, 62 died of other disease2 79 M No No MRSA 32 30 Disease free, 90 P. aeruginosa, died of other disease3 72 M Yes VII P. aeruginosa, 36 30 Disease free, 51 Candida spp ongoing VII palsy
5 66 M Yes VII Negative cultures 59 40 Died of MOE 2 (2 months)6 65 F Yes VII P. aeruginosa, 71 37 Seizure, died of MOE 1 S. aureus (1 month) 7 84 M Yes VII Negative cultures 17 5 Pulmonary Disease free, 72 oedema VII palsy resolved8 78 M Yes XII P. aeruginosa 45 30 Disease free, 94 XII palsy resolved9 65 M Yes No Negative cultures 8 1 Claustrophobia Otorrhoea 80 and otalgia10 71 F No No Negative cultures o/p 30 Disease free, 26 died of other disease11 75 F No No P. aeruginosa 9+o/p 30 Disease free, 38 died of other disease12 84 M Yes VII P. aeruginosa, 43 29 Perforated Recurrence (11 m), 37 S. aureus TM VII palsy, died of other disease13 69 M Yes No S. epidermidis, 42 30 Disease free 43 S. apiospermum14 76 M Yes VII P. aeruginosa, o/p 30 Disease free, 49 Candida spp ongoing VII palsy15 71 M Yes VII (X) P. aeruginosa, 74 39 Recurrence (4 m), 6 Candida spp new X palsy, S. apiospermum died of MOE16 77 F Yes VII, IX, P. aeruginosa 39 30 Pulmonary Disease free, 77 XII oedema ongoing VII palsy, IX & XII resolved 17 77 M Yes VII MRSA, 93 38 Recurrence (5 weeks), 35 Corynebacterium, disease free, ongoing VII palsy
Year Author Patients Cure RateCase series 1982 Lucente17 3 NR1989 Shupak7 2 100 %1992 Davis6 16 100 %2004 Narozny10 8 88 %2010 Present study 17 70 %Case reports1982 Mader9 1 Cured1990 Schweitzer8 1 Cured1998 Bath18 1 Cured2000 Lancaster19 1 Died2005 Singh16 1 Cured
The database of randomised controlled trials in hyperbaric medicine maintained byDr Michael Bennett and colleagues at the Prince of Wales Hospital
Diving and Hyperbaric Medicine Unit is at:
<www.hboevidence.com>
Exceeding the limits - estimated tissue pressures among Western Australian recreational diversPeter Buzzacott, Terri Pikora, Jane Heyworth and Michael Rosenberg
Analyser position for end-tidal carbon dioxide monitoring in a rebreather circuitAlastair Ineson, Kaylene Henderson, David Teubner and Simon Mitchell
S100B and its relation to intravascular bubbles following decompressionMarianne B Havnes, Astrid Hjelde, Alf O Brubakk and Andreas Møllerløkken
Bubble grade0 1 2 3 4 5
Group II (400 kPa; n = 7) 4 3 0 0 0 0Group III (700 kPa; n = 11) 2 0 1 0 0 8
Severe hydrogen sulphide poisoning treated with 4-dimethylaminophenol and hyperbaric oxygenJoerg Lindenmann, Veronika Matzi, Nicole Neuboeck, Beatrice Ratzenhofer-Komenda, Alfred Maier and Freyja-Maria Smolle-Juettner
(
Patient Sex Age CPR Time to Time to Number Diagnosis Intubation ICU Hospital Outcome(yrs) DMAP HBOT HBOT (days) (days) (days)
1 F 39 Yes 90 100 2 VF, cerebral ischaemia & oedema 1 1 1 Deathpulmonary oedema, (day 2)malignant hyperthermia
2 F 40 No 60 100 6 Respiratory shock, pleural effusions 1 2 8 Fullrecovery
3 F 26 No 60 100 6 Respiratory & circulatory shock, 1 2 8 Fullcerebral oedema recovery
4 F 46 No 60 100 11 Respiratory & circulatory shock, 4 5 12 Fullpulmonary oedema, ARDS recovery
5 M 28 No 60 100 8 Respiratory & circulatory shock, 1 2 8 Full‘gas eye’ recovery
6 M 60 Yes 90 125 1 Cardio-respiratory arrest, AF, 7 7 7 Deathcerebral ischaemia & oedema (day 8)pulmonary oedema, ARDS,
Hyperbaric oxygen in the treatment of asphyxia in two newborn infantsAlberto Orozco-Gutierrez, Lucilina Rojas-Cerda, Rosa M Estrada and Cesar Gil-Rosales
Pre-HBOT Post-HBOT 1 Post-HBOT 2 Post-HBOT 3Case 1 CPK total (units) 3069 795 342 493
CK-MB (units) 58 35 29 41LDH (units) 1036 730 645 657
Case 2 CPK total (units) 2156 1230 539CK-MB (units) 77 43 30
EUBS 37th ANNUAL SCIENTIFIC MEETING 201124–27 August 2011
Gdansk, PolandFirst Announcement
Hosts: The National Centre for Hyperbaric Medicine, GdyniaVenue: The Medical University of Gdansk
Main topics:
Contact the organising Committee at:
Visit our website: <www.EUBS2011.org>
Minutes of EUBS Executive Committee Meeting, 17 September 2010, Point Hotel, Istanbul
Minutes of the SPUMS Executive Committee Meeting, 23 May 2010 at Berjaya Resort, Redang Island, Malaysia
22–27 May 2011
Venue: Hilton Resort and Spa, Tumon Bay, Guam
Call for Abstracts, Conference Information and Registration Forms
Themes:Medical aspects of military, occupational and recreational technical divingHead injury and diving workshop – review of clinical cases and guidelines
Management of acute diving injuries
The Head Injury and Diving Workshop will include medical risk assessment for diving
reviewed. Management of acute diving injuries will also be covered in the workshop forum.
Keynote speakers:David Doolette, PhD, US Navy Experimental Diving Unit, Panama City, USA
Simon Mitchell, PhD, FANZCA, The University of AucklandAndrew Fock, FANZCA, The Alfred Hospital, Melbourne
Abstracts:Abstracts for presentations should be submitted before 31 March 2011
If you wish to present a paper please contact:SPUMS ASM 2011 Convenor:
Dr Sarah LockleyE-mail: <[email protected]> or <[email protected]>
Mobile: +61-(0)4-3114-4817
Register via the SPUMS website <www.spums.org.au> or contact the Convenor for a Registration Brochure
Registrations not done via the website will incur a handling fee
The
website is atwww.spums.org.au
Members are encouraged to log in
TheDiving and Hyperbaric Medicine
website is atwww.dhmjournal.com
Readers are encouraged to log in
Important notice: New Continuing Professional Development Coordinator needed for 2011
International Congress on Hyperbaric Medicine
The 17th International Congress on Hyperbaric MedicineCape Town, South Africa
16–19 March 2011
Inter-university Diploma in Diving and Hyperbaric Medicine, France
The Hyperbaric Research Prize
German Society for Diving and Hyperbaric Medicine (GTUeM)
The Australia and New Zealand Hyperbaric Medicine Group
Introductory Course in Diving and Hyperbaric Medicine
Oxygen and Infection; European Committee for Hyperbaric Medicine (ECHM)
Conference Proceedings
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Editorials
SPUMS notices & news
236 Instructions to authors(short version)
235 C o u r s e s , m e e t i n g s a n d advertising
229 Diploma of Diving and Hyperbaric Medicine requirements
230 Minutes of the SPUMS Executive Committee Meeting, 23 May 2010 at Berjaya Resort, Redang Island, Malaysia
232 South Pacif ic Underwater Medicine Society, 40th Annual
Hyperbaric Medicine234 International Congress on
Hyperbaric Medicine
Diving and Hyperbaric Medicine is indexed on SCIE and Embase/Scopus
181 The Editor’s offering182 HBOT for malignant otitis externa
Christian Heiden183 The EUBS President’s page
Diving and Hyperbaric Medicine Volume 40 No. 4 December 2010
223 EUBS Executive Committee224 EUBS 37th Annual Scientific
Meeting 2011224 Minutes of EUBS Executive
C o m m i t t e e M e e t i n g , 1 7 September 2010, at Point Hotel, Istanbul
227 Minutes of EUBS General Assembly 18 September 2010, Istanbul
EUBS notices & news
Continuing professional development
Original articles
Case reportsCourses and meetings
Instructions to authors
222 Breathe easyJohn Parker
213 Severe hydrogen sulphide poisoning treated with 4-dimethylaminophenol and hyperbaric oxygenJoerg Lindenmann, Veronika Matzi, Nicole Neuboeck, Beatrice Ratzenhofer-Komenda, Alfred Maier, Freyja-Maria Smolle-Juettner
218 Hyperbaric oxygen in the treatment of asphyxia in two newborn infantsAlberto Orozco-Gutierrez, Lucilina Rojas-Cerda, Rosa M Estrada and Cesar Gil-Rosales
184 Acute antioxidant pre-treatment attenuates endothelial microparticle release after decompressionBryna C R Chrismas, Adrian W Midgley, Lee Taylor, Rebecca V Vince, Gerard Laden, Leigh A Madden
189 ‘Sea legs’: sharpened Romberg test after three days on a live-aboard dive boatClinton R Gibbs, Katherine H Commons, Lawrence H Brown and Denise F Blake
195 Malignant otitis externa: experience with hyperbaric oxygen therapyAlex Saxby, Michael Barakate, Thomas Kertesz, Joanne James, Michael Bennett
201 Exceeding the limits - estimated tissue pressures among Western Australian recreational diversPeter Buzzacott, Terri Pikora, Jane Heyworth, Michael Rosenberg
206 Analyser position for end-tidal carbon dioxide monitoring in a rebreather circuitAlastair Ineson, Kaylene Henderson, David Teubner and Simon Mitchell
210 S100B and its relation to intravascular bubbles following decompressionMarianne B Havnes, Astrid Hjelde, Alf O Brubakk and Andreas Møllerløkken
221 CME Activity 2010/4HBOT and malignant otitis externaMichael Bennett
Poem