H
NaNH2 R
H
R
O
H Reaction of internal alkynes: Hydrogenation SYN addition of H2 - H2/Pd/C, quinoline poison to afford Z alkene ANTI addition of H2 - Na/NH3 to afford E alkene
REACTION OF ACETYLIDE ANIONS WITH ELECTROPHILES
O
Aldehydes
epoxides
OH
RETROSYNTHETIC ANALYSIS
A process of reasoning backwards from a target molecule to a suitable set of starting materials
Br
H
H
Br
SYNTHESIS