In this workshop 45 world class scientists will review the latest approaches of gene therapy, presenting the major

aspects and cutting edge techniques: from basic knowledge of genome dynamics, structure, organization and expression to the recent technologies of gene editing

and vector development for clinical trials. We foster all researchers, especially PhD students, to

submit an abstract to present a poster, and we shall select 23 of them to give an oral presentation.

EMBO Workshop:

Modern DNA concepts and

tools for safe gene

transfer and modification

University of Evry-Val-d’Essonne (UEVE) IBGBI, 23 Boulevard de France, Evry, France

More information, program, registration,

venue, sponsoring:

www.moderndnaconcepts.org

Sessions and confirmed speakers

New DNA visions, technologies and applications

Daniel CHOURROUT, Bergen (Norway) Jean François DELEUZE, Evry (France) Daniel C. KOBOLDT, St Louis (MO, USA) Hans LEHRACH, Freiburg (Germany) Topology and plasticity of genome

Bernard De MASSY, Montpellier (France) Lumir KREJCI, Prague (Czech Republic) Zoi LYGEROU, Patras (Greece) Rolf OHLSSON, Stockholm (Sweden) Florian PAULER, Vienna (Austria) Pier Lorenzo PURI, La Jolla (CA, USA) Angela TADDEI, Paris (France) RNAs and gene expression

Irene BOZZONI, Rome (Italy) Witold FILIPOWICZ, Basel (Switzerland) Nicole SCHONROCK, Sidney (Australia) Gene targeting 1: Biology, technologies & tools Sherry CHAPPELL, St Louis (IL, USA) Emmanuelle CHARPENTIER, Braunschweig (Germany) Nadia GUETTARI, and Paris, France) Katherine A. HIGH Philadelphia (PA, USA) Fulvio MAVILIO, Evry (France) Jacob Giehm MIKKELSEN, Aarhus (Denmark) Supriya SHIVAKUMAR, St Louis (USA Gene targeting 2: Applications

Toni CATHOMEN, Freiburg (Germany) Bruno PÉAULT, Edinburg (United Kingdom)

Gene targeting 3: Bio-safety

Toni CATHOMEN Freiburg (Germany) Klaus CICHUTEK, Langen (Germany) Nicolas FERRY, Paris (France) Bruce LEVINE, Philadelphia (PA, USA) Ute MODLICH, Langen (Germany)

Vectorology 1: Current state, perspectives and biosafetyOlivier DANOS, New York (NY, USA) Federico MINGOZZI, Paris/Evry (France) Harald PETRY, Amsterdam (Netherlands) Vectorology 2: Recent vectors advances for diseases Andrew BAKER, Glasgow (United Kingdom) Philippe MOULLIER, Nantes (France) Adrian THRASHER, London (United Kingdom) Vectorology 3: European effort for brain gene therapyLudivine BREGER, Lund (Sweden) Atze DAS, Amsterdam (Netherlands) Eric KREMER, Montpellier (France) Liliane TENENBAUM, Lausanne (Switzerland) Vectorology 4: Viral vectors for genome editing Manuel GONÇALVES, Leiden (Netherlands) Jude SAMULSKI, Chapel Hill (NC, USA) Vectorology 5: Clinical trials: present and future Alessandra BIFFI (Milan, Italy) Nathalie CARTIER (Paris, France) Anne GALY (Evry France) Adrian THRASHER, London (United Kingdom): Edward TUDDENHAM, London, (United Kingdom) Closing lecture Serge BRAUN, Evry (France)

+ Video-demonstrations on technologies and tools of gene editing

+ 23 short presentations will be selected among young participants

+ Permanent poster sessions, exhibit spaces, networking activities and social events

Deadline for abstract submission:

for oral presentation: January 30th, 2015 for poster presentation: February 27th, 2015

Registration fees:

Participants from academia: 450 € Participants from industry: 600 €

Students under 30 years of age: 300 €

Travel grants can be obtained by students and post-

docs selected to give an oral presentation

(see the website for details)

Scientific & Organisation committee:

Ludivine BREGER, Lund University Karine CHARTON, Généthon Aude ESCANDE, UEVE, Evry

Sylvain FISSON, UEVE/ Généthon Anne GALY, INSERM/UEVE/ Généthon Fulvio MAVILIO, President, Généthon Otto-Wilhelm MERTEN, Généthon

Mauro MEZZINA, EASCO, Paris Isabelle RICHARD, CNRS/UEVE/ Généthon

Daniel STOCKHOLM, EPHE/ Généthon

Martine THIBAUT, EASCO, Paris

www.moderndnaconcepts.org

For any further information, please, contact the organization manager: mezzina@easco.org

Interested participants can sign up by now on http://events.embo.org/coming-soon/index.php?EventID=w15-42