enabling data defensibility and laboratory productivity...
TRANSCRIPT
“
Enabling Data Defensibility and Laboratory Productivity Using a Laboratory Execution System”
Narragansett Bay Commission
Providence, RI
Challenges in the QA/QC Space
Public and Private labs need to reduce costs without compromising quality • Our customers need solutions that let QA/QC maintain their high
attention to detail, but that shorten the time and cost required to qualify an area or material for use, and communicate that information quickly to the right people
• Solutions that can deliver metrics on operational effectiveness and
drive the reduction/elimination of non-value added tasks are critical to meeting their business objectives
• A key factor includes traceability and defensibility, quickly and easily finding your results, raw data, audit trail, approval process, etc.
• Automatically • Enforce all SOPs and Methods
• Connect field samplers directly to the lab
• Verify instrument calibration
• Check reagent expiry and reorder
• Verify Analyst Certifications
• Store worksheets electronically
• Check Specs before committing to LIMS
• e-Signatures on all transactions if desired
• Enable the lab to become paperless
• Facilitate TNI/ISO 17025 Certification
Narragansett Bay Commission
With our New LES – Laboratory Execution System
• Electronic Worksheets to replace all paper in the laboratory
• iPads to collect field sampling information and metadata
• Touch screen monitors for sample receipting
• Automated bi-direction instrument interfacing for all lab equipment
• SharePoint as the document management system and to capture all lab worksheets
• HachWIMS software to integrate lab and plant data, and generate reports
• Integration of 3 wind turbines provide around half of the site’s power needs – also interfaced to the WIMDS
• Publishing data to our customers through a web portal
Narragansett Bay Commission
NBC addressed these challenges and the solution integrates..
Why would we needed an LES
= Sample Tracking (LIMS)
= ELN
= Instrument Connection
Sample Prep
15%
Perform Analysis
40%
Data Entry
15% Solution
Prep
10%
Sample
Submissions
10%
Work
Assignment 5%
Sample
Reporting 5%
Benchtop activities account for 65% of
time spent by laboratory personnel
LIMS addresses
20%
of Laboratory
Operations
Where was the paper?
do part of the job
Work Scheduling
Sample Preparation
Inventory Tracking
Instrument Calibration
Training Records
Standard Procedures
& Bench Sheets
Instrument Reports
Customer Reports / COA
LIMS
SDMS Calibration
Training Inventory
ELN
Previous attempts at reducing paper
need to be Integrated to gain real value
Work Scheduling
Sample Preparation
Inventory Tracking
Instrument Calibration
Training Records
Standard Procedures
& Bench Sheets
Instrument Reports
Customer Reports / COA
LIMS
SDMS Calibration
Training Inventory
ELN/LES
Our solution is totally vendor neutral for instruments
Narragansett Bay Commission
LIMS
SDMS Calibration
Training Inventory
ELN/LES
LEVERAGE EXISTING
INVESTMENTS
How does paper impact our lab?
• Paper based processes introduce risk areas, bottlenecks and costs:
• Risks – Transcription errors (3%-5%) – Procedural errors - Deviation from SOP – Calculation errors – miscalculations (ex. 1+1=3) – Transcription errors – Illegibility (ex. Was that 3 or 8?) – Omissions of data/information – Loss / destruction of paper / Illegibility
• Bottlenecks – Data transcription, double and triple transcription of information that
already exists – Manual calculations – Lack of real-time feedback, delays in decisions and actions
• Costs – Hard Costs – paper, notebooks, storage, consumables – Soft Costs – human errors, investigations, corrective actions
Paper forms are easy to use, but disconnected and impede data flow
Analyst Qualified ? Certified ?
Training ? Present?
Instrument Calibrated ?
Inventory Expired ? Reorder?
Document Management
Instruments
LIMS/ERP/SAP/ Other Informatics
System
Example Form
Instrument Data
Record Retention $1600 per month/month
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Inventory Management
Locate, track and manage materials
Asset Utilization
Monitor usage, optimize investments,
track KPIs
Instrument and Systems Integration
Electronic data transfer, eliminating
manual transcription
Sample Management
Validate Analyses/Samples with ESigs
Electronic Lab Notebooks and Worksheets
Eliminate paper, automate processes and ensure procedural
execution
Execute
Track
Manage
Narragansett Bay puts it all together
Narragansett Bay Commission
Interface
Utilize
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Laboratory Execution System • Sample Centric • Repetitive Analysis • Procedural Adherence & Execution
Leverage existing processes to build an electronic environment
• Utilize current:
• Worksheets, bench forms, log books
• Standard Operating Procedures
Zero footprint web browser interface
Industry leading ReDI™ technology enables rapid deployment • Implement worksheets in hours vs days
Highly integrated to other lab software
Execute
LES
Narragansett Bay Commission
Narragansett Bay Commission
Field Inspectors
• “The purpose of The NELAC Institute (TNI) National Environmental Field Activities Program (NEFAP) is to establish and implement an accreditation program for field sampling and measurement organizations (FSMOs).”
Sample Collection on iPads
How did we convert our paper forms to electronic?
Current paper forms become electronic forms
Automated Worksheet Automation / Integration Controls
Procedures-based ELN dramatically enhances lab productivity
Problems with paper Benefits of Automation
- Illegible handwriting/transcription errors
- Information recorded where it should not be
- Image printed/pasted onto page
- Ultimately no control
- Legible text
- All information electronically traced
- Selection from pre-defined lists
- Electronic signature
- Insert image electronically
- Controlled execution –step by step
Electronic Notebooks– Real Time Integration…
Narragansett Bay Commission
pH and Percent Titratable Acidity Worksheet
LIMS
Inventory System
Calibration System
Instrument Data
Automated Calculations
Everything is in one place
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Leading interfacing platform for the last 20 years
Solution provides the “Information Wiring” for electronic data transfer in the laboratory
Used to integrate instruments & instrument data systems to a wide variety of Enterprise applications including: • ELN, LES, LIMS, SDMS, DMS, SAP, etc...
Scalable application can be deployed as: • Workstation Application on a single PC • Client /Server solution supporting centralized
database, security and audit components • Regulatory compliance (e.g. 21CFR Part11,
GxP)
Instrument and Systems Integration
Narragansett Bay Commission
Interface
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Emergence of “Data Discovery and Visualization”
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REPORTING STATS
Highly Structured Predetermined
Questions
Control-based
IT Dependent
Lengthy Ask-To-Answer Loops
“Deep Analytics”
Valuable, But Complicated to use
Limited to Power Users
Lengthy Ask-To-Answer Loops for end-
users
ANALYTICS & DATA
DISCOVERY
Free of Dimensional
Constraints
New Questions
User-Driven
Agile, Self Service
Predictive
Empowerment-based
Too Much Information?
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The NBC Analytics Platform
Exploratory analysis, dashboard apps &
predictive analytics.
Easy, Fast and Smart for visualizing and
understanding any data.
We help people make better decisions,
spot new opportunities, and avoid risks.
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Inventory Management
Instrument & Equipment Management
Training and Certification
Asset Utilization
Monitor usage, optimize investments,
track KPIs
Instrument and Systems Integration
Electronic data transfer, eliminate
manual transcription
Laboratory Information Management Systems
Schedule, assign, test, and report
Laboratory Execution System
Eliminate paper, automate processes and ensure procedural
execution
Execute
Track
Manage
iLAB Laboratory Execution System Overview
Narragansett Bay Commission
… an Integrated Platform
Interface
Visualize
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• Business intelligence for laboratory asset
optimization; people, equipment & processes
• Collect, Consolidate and Add Context to Data
• Simple Information in a Usable & Actionable
Format
Bring data into decisions
Insight through visualization
Informed decisions
• Lab Analytics
Utilization data (assets, method, people)
Trend analysis
Comparison analysis
# of samples, injections, and errors
iLAB – Analytics and Visualization
Narragansett Bay Commission
Visualize
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• Visualize data from many sources including
LIMS, SCADA, etc
• Access Spotfire dashboards from within LES
Portal
iLAB – Analytics and Visualization
Narragansett Bay Commission
Visualize
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• Spotfire can be used to recall data from iLAB
• Select worksheet reference in dashboard
that opens read-only view of a completed
worksheet
iLAB – Analytics and Visualization
Narragansett Bay Commission
Visualize
• A worksheet reference was
configured as a URL
• When the URL is followed a
view of the worksheet is
provided
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• All data is cross-linked to help the user
analyze the data more effectively
• Facilitates rapid data drill down
• Typical scenario: Find reason for testing
delays in laboratory
• Select one an area in one chart and
highlight those selections in others…
• Reduce data in table to the selected
items only..
• Initial finding; Analysts completing work in
timely fashion but approvers appear to be the
cause of the delays.
• Is it one approver?
• Why the delay? Procedural issue?
iLAB – Analytics and Visualization
Narragansett Bay Commission
Visualize
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• New dashboards configured as needed
• Dashboard can “mash up” data from
external sources in addition to iLAB
• Dashboard can be configured to
provide “guided” analytics for
infrequent users
• Dashboards can be used outside of
iLAB environment when appropriate
• Dashboard is stored in Webplayer and
accessible through URL
• iLAB Portal is configured to load new
dashboard
iLAB – Analytics and Visualization: Setup
Narragansett Bay Commission
Visualize
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Dashboard 1: Track projects by Location, Technician and Priority
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Dashboard 2: Lab Analytics on Delays, Priorities and Productivity
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Dashboard 3: Business Intelligence for Laboratory Asset Optimization; People, Equipment & Processes
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Dashboard 6: Control Charts
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Easy Collaboration and Report Generation All-in-One Solution
Data Mining
Desktop Application
Author dashboard
Update reports
WebPlayer
Online report
Zero-Installation
Read-only Views
Interactive interface
Instrumentation Manager
Project Managers
Technicians Data Warehouse
Data Analysts
Collaborators, Reviewers, End users
Data Analysts
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Narragansett Bay Conclusions
Narragansett Bay Commission
LES integrates people, procedures and lab
systems to provide real time workflow control at
the bench level and assure defensible data
Maintain high attention to detail while reducing the
time and cost required to qualify an area or material for
use
Quickly communicate critical information to support
business decisions
Deliver metrics on operational effectiveness and drive
the reduction/elimination of non-value added tasks
Reduce the time and effort needed to capture,
document, and manage data