ENHANCING DETECTION.... ENHANCING YOUR PRACTICE ENHANCING DETECTION.... ENHANCING YOUR PRACTICE

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<ul><li> Slide 1 </li> <li> ENHANCING DETECTION.... ENHANCING YOUR PRACTICE ENHANCING DETECTION.... ENHANCING YOUR PRACTICE </li> <li> Slide 2 </li> <li> Staggering Statistics on Oral Cancer 1 person dies from oral cancer each hour of every day The Mortality Rate for oral cancer has not decreased in over 30 years 72% of the cases of oral cancer are not diagnosed until stage two or later Late detection results in a five year survival rate of only 52% Cases of oral cancer are increasing at an alarming rate </li> <li> Slide 3 </li> <li> Public Awareness of Oral Cancer Must Improve 41,350 new cases of oral cancer were discovered in 2013 Oral cancer impacted 3X as many people in 2013 when compared to cervical cancer (41,350 cases versus 12,340 cases respectively) HPV is increasing the number of oral cancer cases There has been a 60% increase in oral cancer in adults under the age of 40 (25% of these cases have no traditional risk factors (smoking, drinking, etc.) </li> <li> Slide 4 </li> <li> New England Journal of Medicine, 2007 Oral HPV infection is strongly associated with oropharyngeal cancer among subjects with or without the established risk factors of tobacco and alcohol use. </li> <li> Slide 5 </li> <li> 5 Early Dysplasia Moderate Dysplasia Severe Dysplasia Carcinoma-In-Situ (CIS) Invasive Squamous Cell Carcinoma (SCC) Appropriate Stage for Discovery &amp; Intervention Potentially Malignant Disease Stages EARLY DETECTION IS THE KEY 67% of all oral cancer is currently discovered beyond this stage. (Stage II) </li> <li> Slide 6 </li> <li> VELscope VX The Technology A safe blue light (no radiation) shines through the epithelial tissue and basement membrane to the stromal collagen Patented technology filters out everything except the fluorescence of the tissues Healthy tissue reflects back through the scope as a brilliant green color Suspicious tissue will absorb the light and not fluoresce, appearing extremely dark, almost black </li> <li> Slide 7 </li> <li> Normal Floor of the Mouth </li> <li> Slide 8 </li> <li> Images courtesy of the British Columbia Oral Cancer Prevention Program Obvious Dysplasia? </li> <li> Slide 9 </li> <li> Copyright 2002-2007 by Oral Health Study, Oral Oncology/Dentistry, BCCA Clinical Appearance (Visible White Light) Loss of Fluorescence Carcinoma-In-Situ (CIS) Fluorescence Visualization </li> <li> Slide 10 </li> <li> Clinical Appearance Suspicious region is now clearly visible. Confirmed CIS. Polyp Images courtesy of the British Columbia Oral Cancer Prevention Program Dysplasia Caught Early Mild Dysplasia CIS Polyp (green) </li> <li> Slide 11 </li> <li> Severe Dysplasia on Alveolar Ridge Clinical Impression: Denture Trauma? Excisional Biopsy: Severe Dysplasia Images courtesy of the University of Washington Oral Medicine Program Inflammation resolved in 2 weeks after removal of denture </li> <li> Slide 12 </li> <li> Images courtesy of the British Columbia Oral Cancer Prevention Program When Do Observe or Refer? </li> <li> Slide 13 </li> <li> Oral Lesions May Show as Irregular, Dark Areas Images courtesy of the British Columbia Oral Cancer Prevention Program Observe or Refer? Excisional Biopsy: Severe Dysplasia </li> <li> Slide 14 </li> <li> An Oral Lesion that Shows No Change in Autofluorescence Appearing Pale Green Images courtesy of the British Columbia Oral Cancer Prevention Program Observe or Refer? Hyperplasia </li> <li> Slide 15 </li> <li> SCC New York University, Dept of Oral Medicine </li> <li> Slide 16 </li> <li> Moderate Dysplasia Dept of Oral Medicine, University of Washington </li> <li> Slide 17 </li> <li> Pre-clinical discovery Left palate : low-grade mucoepidermoid carcinoma </li> <li> Slide 18 </li> <li> Using an instrument to blanch is a technique 1 for indicating whether or not an abnormality has an inflammatory component. This particular area is inflammation and blanches completely Treatment and follow-up in two weeks showed complete resolution 1.Rudd M, Eversole R, Carpenter W. Diascopy: a clinical technique for the diagnosis of vascular lesions, Gen Dent. 2001 Mar-Apr; 49(2):206-9. Blanching under Diascopic Pressure </li> <li> Slide 19 </li> <li> 19 EXTENSIVE CLINICAL SUPPORT 10+ Years of Research in the Oral Cavity 2011 General Dentistry E. Truelove, et al. 2009 General Dentistry K. Huff, et al 2007 Head &amp; Neck P.M. Williams, et al. 2006 Clinical Cancer Research C.F. Poh, et al 2005 Oral Oncology deVeld, et al. Proven Efficacy www.VELscope.com/research </li> <li> Slide 20 </li> <li> Since we have incorporated the VELscope in our practice we have had three positive oral carcinomas treated by oral and plastic surgeons in 2 1/2 years. Numerous biopsies have resulted in the removal of worrisome and non malignant growths which has increased our patient acceptance and referrals. Thanks for the technology. Thomas R. Leischner DDS Elk Grove Village, IL </li> <li> Slide 21 </li> <li> Portable Cordless Affordable: $3,299.00 </li> <li> Slide 22 </li> <li> THANK YOU! </li> </ul>

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