enlight- partner meeting, 18 -19 june 2009, ific- valencia manjit dosanjh enlight coordinator &...

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ENLIGHT- PARTNER Meeting, 18 -19 June 2009, ENLIGHT- PARTNER Meeting, 18 -19 June 2009, IFIC- Valencia IFIC- Valencia Manjit DOSANJH ENLIGHT Coordinator & CERN

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Page 1: ENLIGHT- PARTNER Meeting, 18 -19 June 2009, IFIC- Valencia Manjit DOSANJH ENLIGHT Coordinator & CERN

ENLIGHT- PARTNER Meeting, 18 -19 June 2009, IFIC- ENLIGHT- PARTNER Meeting, 18 -19 June 2009, IFIC- ValenciaValencia

Manjit DOSANJH

ENLIGHT Coordinator & CERN

Page 2: ENLIGHT- PARTNER Meeting, 18 -19 June 2009, IFIC- Valencia Manjit DOSANJH ENLIGHT Coordinator & CERN

History

ENLIGHT was established in 2002

Composed of: HIT, ETOILE, CNAO, CERN, ESTRO, GSI, Karolinska, MedAustron, TERA, Czech Rep, Spain

Funded as a network by the EC, 2002 - 2005

Main achievements:•Creation of a European Hadrontherapy Community•Common multidisciplinary platform with a common vision•Served as a vehicle for education and dissemination

At the end of the funding:ENLIGHT community showed clear desire for continuing and helping new initiatives….

2Manjit Dosanjh, ENLIGHT Meeting, IFIC- Valencia, 19 June 2009

Page 3: ENLIGHT- PARTNER Meeting, 18 -19 June 2009, IFIC- Valencia Manjit DOSANJH ENLIGHT Coordinator & CERN

Manjit Dosanjh, ENLIGHT Meeting, IFIC- Valencia, 19 June 2009

ENLIGHT provides a multidisciplinary European collaboration amongst partners interested in hadrontherapy

ENLIGHT acts as a platform for defining research needs

Developing projects and securing funding and collaboration

ENLIGHT is a useful resource for other communities interested in hadrontherapy

ENLIGHT++ in 2009

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Page 4: ENLIGHT- PARTNER Meeting, 18 -19 June 2009, IFIC- Valencia Manjit DOSANJH ENLIGHT Coordinator & CERN

What are the needs of the community?

• Trained researchers in this new multidisciplinary

field

• Access to the facilities and beam time for research

• Imaging, TPS, organ-motion …….

• Information sharing and networking

• Improving present technologies/facilities

• Funding ………………………………….

Manjit Dosanjh, ENLIGHT Meeting, IFIC- Valencia, 19 June 2009 4

Page 5: ENLIGHT- PARTNER Meeting, 18 -19 June 2009, IFIC- Valencia Manjit DOSANJH ENLIGHT Coordinator & CERN

THE PARTNER PROJECT

PARticle Training Network for European Radiotherapy

TRAINING

ClinicalBiologicalTechnical (Instrumentation)

Young Researchers Future Leaders in Ion Therapy

RESEARCH

Manjit Dosanjh, ENLIGHT Meeting, IFIC- Valencia, 19 June 2009 5

Page 6: ENLIGHT- PARTNER Meeting, 18 -19 June 2009, IFIC- Valencia Manjit DOSANJH ENLIGHT Coordinator & CERN

Ten Institutes:CERN (Project Coordinator), CNAO, GSI, UKL-HD (HIT), KI, UNIS, TERA, MEDAUSTRON, ETOILE, IFICTwo leading companies in particle therapy: IBA, SIEMENSMulti-disciplinary research: Radiobiology, Dosimetry, Treatment Planning, Novel gantry design, Simulations, Clinical studiesMobility of researchers and a common network

THE PARTNER PROJECT

Joint Research & Training Programme

Manjit Dosanjh, ENLIGHT Meeting, IFIC- Valencia, 19 June 2009 6

Page 7: ENLIGHT- PARTNER Meeting, 18 -19 June 2009, IFIC- Valencia Manjit DOSANJH ENLIGHT Coordinator & CERN

1.Clinical Studies: 1 ER, CNAO; 1 ER, HIT

2 ER

2.Epidemiology & Patient Selection: 1 ER, CNAO; 1 ER, HIT

2 ER

3. Radiobiology: 2 ESR, GSI; 2 ESR, KI ; 1 ESR, Surrey

5 ESR

4. Treatment Planning:1 ESR, Surrey; 2 ESR, IBA; 1 ESR, MedAustron

4 ESR

5.Simulation and Dosimetry – GEANT/FLUKA: 1 ESR, CERN; 1 ER, HIT; 1 ESR, Siemens

2ESR + 1ER

6.Image Guided Hadron Therapy: 1 ESR, CNAO; 1 ESR, Siemens

2 ESR

7.PET prototype, In-situ Monitoring; 1 ESR, KI; 1 ESR, TERA

2 ESR

8. Novel Gantry design:1 ESR, CNAO

1 ESR

9.ICT and prototype GRID: 3 ESR, CERN

3 ESR

10.Novel accelerator study: 1 ESR, TERA

1 ESR

TOTAL 20 ESR + 5 ERPARTNER KICK-OFF MEETING, 16-17 October, 2008

Page 8: ENLIGHT- PARTNER Meeting, 18 -19 June 2009, IFIC- Valencia Manjit DOSANJH ENLIGHT Coordinator & CERN

Key details for PARTNER

Contribution from European Commission: 5.6 M€ 25 young researchers

PARTNER wide training in all collaborating institutes

20 technical training workshops in hadron therapy

open to all young researchers:

www.cern.ch/partner

8 Manjit Dosanjh, ENLIGHT Meeting, IFIC- Valencia, 19 June 2009

Page 9: ENLIGHT- PARTNER Meeting, 18 -19 June 2009, IFIC- Valencia Manjit DOSANJH ENLIGHT Coordinator & CERN

EU: Infrastructure FP7

ULICEUnion of Light Ions

Centres in Europe

Three types of activities are in the project

Trans-national Access (TA) Joint Research Activities (JRA) Networking Activities (NA)

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Courtesy of Prof. Roberto Orecchia, CNAO

Manjit Dosanjh, ENLIGHT Meeting, IFIC- Valencia, 19 June 2009

Page 10: ENLIGHT- PARTNER Meeting, 18 -19 June 2009, IFIC- Valencia Manjit DOSANJH ENLIGHT Coordinator & CERN

No. Organisation (full name) Short Name Country

1 Centro Nazionale di Adroterapia Oncologica CNAO Italy

2 Medical University of Vienna MUV Austria

3 University Hospital of Heidelberg UKL-HD Germany

4 CERN CERN Switzerland

5 MedAustron MEDA Austria

6 Etoile ETOILE France

7 RKA Marburg UKM Germany

8 Gesellschaft für Schwerionenforschung GSI Germany

9 Karolinska Instititute KAR Sweden

10 Oxford University UOXF UK

11 Technical University of Dresden TUD Germany

12 Siemens AG - MED PT PLM P SAG Germany

13 European Society for Therapeutic Radiology and Oncology ESTRO Belgium

14 Université Catholique de Louvain UCL Belgium

15 Medical University Aarhus AAR Denmark

16 Radboud Medical University Nijmegen UMCN Netherlands

17 Ion Beam Applications SA IBA Belgium

18 Istituto Nazionale di Fisica Nucleare INFN Italy

19 Maria Skłodowska Curie Memorial Institute Krakow COOK Poland

20 Archade ARC France

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ULICEUnion of Light Ion Centres in Europe

Manjit Dosanjh, ENLIGHT Meeting, IFIC- Valencia, 19 June 2009

Page 11: ENLIGHT- PARTNER Meeting, 18 -19 June 2009, IFIC- Valencia Manjit DOSANJH ENLIGHT Coordinator & CERN

ULICEUnion of Light Ion Centres in Europe

ULICE is a multidisciplinary initiative that involves all the major players in Europe in the field of hadrontherapy, integrating clinical, physical, biological, and technological knowledge

ULICE structure :

- General coordination: Roberto Orecchia, CNAO - Trans-national access: Juergen Debus, HIT - Joint research activities: Richard Poetter, Vienna

University- Networking activities: Manjit Dosanjh, CERN

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Page 12: ENLIGHT- PARTNER Meeting, 18 -19 June 2009, IFIC- Valencia Manjit DOSANJH ENLIGHT Coordinator & CERN

ULICE

The development of new instruments, the transnational European access to the existing facilities and the different communities (researchers, clinicians, patients) requires a broad network structure. The overall aims of ULICE are:

• enable the full exploitation of all available resources

• access to information• improvement of the existing and upcoming

facilities

Manjit Dosanjh, ENLIGHT Meeting, IFIC- Valencia, 19 June 2009 12

Page 13: ENLIGHT- PARTNER Meeting, 18 -19 June 2009, IFIC- Valencia Manjit DOSANJH ENLIGHT Coordinator & CERN

• provide beam-time for external researchers through clinical

trial programmes aimed at improving different technical

aspects of the facilities.

• provide beam-time through ‘open requests’ from external

researchers for radiobiological and physics experiments

Manjit Dosanjh, ENLIGHT Meeting, IFIC- Valencia, 19 June 2009 13

ULICE: Transnational access

Page 14: ENLIGHT- PARTNER Meeting, 18 -19 June 2009, IFIC- Valencia Manjit DOSANJH ENLIGHT Coordinator & CERN

• Develop methods to match the volume treated by

active scanning particle beams to the target volume

• Develop novel adaptive treatment planning• identify tumours that need the superior physical

selectivity provided by ion beams• Develop/investigate a new carbon ion gantry design• Develop computer assisted patient selection program based on epidemiologocal and other data

Manjit Dosanjh, ENLIGHT Meeting, IFIC- Valencia, 19 June 2009

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ULICE: Joint Research Activities

Page 15: ENLIGHT- PARTNER Meeting, 18 -19 June 2009, IFIC- Valencia Manjit DOSANJH ENLIGHT Coordinator & CERN

European project: ULICE

Status of the project:

Approved (8.4 M Euro)

Negotiation closed

Grant agreement to be signed

Project to start in 2009

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Page 16: ENLIGHT- PARTNER Meeting, 18 -19 June 2009, IFIC- Valencia Manjit DOSANJH ENLIGHT Coordinator & CERN

ENVISIONEuropean Novel imaging systems for in vivo monitoring and quality

control during tumour ion beam therapy

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Page 17: ENLIGHT- PARTNER Meeting, 18 -19 June 2009, IFIC- Valencia Manjit DOSANJH ENLIGHT Coordinator & CERN

ENVISIONENVISIONCoordinator: Manjit Dosanjh

Approved for 6M Euros

Development of new solutions for

▪ real-time, in-vivo monitoring

▪ quantitative imaging

▪ precise dose quantification

▪ feedback to treatment planning

▪ real-time feedback for moving

organs

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Courtesy of Prof. Amaldi

Manjit Dosanjh, ENLIGHT Meeting, IFIC- Valencia, 19 June 2009

Page 18: ENLIGHT- PARTNER Meeting, 18 -19 June 2009, IFIC- Valencia Manjit DOSANJH ENLIGHT Coordinator & CERN

Manjit Dosanjh, IFIMED Symposium,10 June 2009 Valencia18

F. Sauli (TERA) and M. Rafecas (CSIC)

W. Enghardt (Oncoray) and D. Dauvergne (CNRS/ETOILE)

K. Parodi (UKL-HD) and G. Baroni (Polimi/TERA)

D. Georg (MUW) and B. Jones (UOXF)

G. Battistoni (INFN) and I. Buvat (CNRS)

18Courtesy of Prof. Amaldi

Page 19: ENLIGHT- PARTNER Meeting, 18 -19 June 2009, IFIC- Valencia Manjit DOSANJH ENLIGHT Coordinator & CERN

ENVISION will complement ULICE project in that it focuses on investigating and increasing the potentials and quality of time-resolved in beam PET imaging for real-time in-vivo dosimetry of moving targets.

Manjit Dosanjh, ENLIGHT Meeting, IFIC- Valencia, 19 June 2009

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ENVISION

Page 20: ENLIGHT- PARTNER Meeting, 18 -19 June 2009, IFIC- Valencia Manjit DOSANJH ENLIGHT Coordinator & CERN

HadroNET(Pawel OLKO)

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Page 21: ENLIGHT- PARTNER Meeting, 18 -19 June 2009, IFIC- Valencia Manjit DOSANJH ENLIGHT Coordinator & CERN

Future Perspectives

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Page 22: ENLIGHT- PARTNER Meeting, 18 -19 June 2009, IFIC- Valencia Manjit DOSANJH ENLIGHT Coordinator & CERN

FP7-PEOPLE-2010-ITN (Initial Training Network)

Call date: Sept 8th 2009Submission date: Dec. 22nd 2009

Could form a training platform linked to ENVISION

Manjit Dosanjh, ENLIGHT Meeting, IFIC- Valencia, 19 June 2009

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Training Network

Page 23: ENLIGHT- PARTNER Meeting, 18 -19 June 2009, IFIC- Valencia Manjit DOSANJH ENLIGHT Coordinator & CERN

      

No. 69 - Hadron therapy facilities. A follow-up project of ULICE will be strongly encouraged for the third Call (Jan 2012).

Justification: An FP7 Integrating Activity will be funded until early 2013 (“ULICE” project).

Manjit Dosanjh, ENLIGHT Meeting, IFIC- Valencia, 19 June 2009

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Integrating Activity projects until the end of FP7 (Draft)

Page 24: ENLIGHT- PARTNER Meeting, 18 -19 June 2009, IFIC- Valencia Manjit DOSANJH ENLIGHT Coordinator & CERN

Composition of ENLIGHT steering committee……………

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Page 25: ENLIGHT- PARTNER Meeting, 18 -19 June 2009, IFIC- Valencia Manjit DOSANJH ENLIGHT Coordinator & CERN

ENLIGHT Steering Committee (I)

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Page 26: ENLIGHT- PARTNER Meeting, 18 -19 June 2009, IFIC- Valencia Manjit DOSANJH ENLIGHT Coordinator & CERN

ENLIGHT Steering Committee (II)

Manjit Dosanjh, ENLIGHT Meeting, IFIC- Valencia, 19 June 2009

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