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ENZYME SCIENCE IS COMMITTED TO PROVIDING HEALTH CARE PROFESSIONALS:

• Most potent and innovative blends of plant-based, Digestive and Therapeutic enzyme formulas on the market exclusively sold to health care professionals

• Clean and pure, 100% vegetarian, products with absolutely no fillers

• Cutting edge exclusive technology: ATPro™ Blend, Thera-blend™, NT-020

• An accessible education and training department

• Enzyme Science is a division of Enzymedica – The category leader in Digestive & Enzyme Health

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ENZYMES •Biologically active proteins that are necessary for life to exist.

•Unique protein structures unique functions.

•Catalyze and regulate every biochemical reaction that occurs within the human body, making them essential to cellular function and overall health.

• Accelerate, modify or direct all bodily function

• Enzymes have been described as the body’s ‘labor force’- “tools”

• It involves using one chemical in the body and making another, without itself being changed

• Alpha + enzyme Beta + unchanged enzyme

• Without enzymes, activity and life STOPS!

ENZYMES

Conservation of Energy*

Wellness

•Energy Conservation is one of the body’s mechanisms of survival

Uses

•Digestive • Taken with first bite of food

•Therapeutic • Taken on an empty stomach

• (1 hr before eating or 2 hrs after) carolguze.com

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THERAPEUTICS

PROTEOLYTIC ENZYMES

How protease works in the body • Absorption into the blood • Bind to Alpha 2 macroglobulin (A2M)

• “Ambulance” • Hydrolyze Proteins

• Dead, Damaged or Don’t Belong (3-Ds)

99% of things that make us sick protein matrix • Foreign Antigens • Excess production of mucus • Excess fibrin • Injury

systemicenzymesupport.org

• 100's of studies on ways to assist wound healing and bruising. Including Supplemental Oral Enzyme Therapy.

• Studies on Sports Injuries in Germany and Australia

Those with enzymes had significantly less pain, less inflammation, shorter time for hematoma to disappear (p<.01).

Kleine, M.W. Vogler, W "The effects of an oral enzyme treatment on experimentally induced hematomas" Forum Gen. Pract. 2:27 (1968). Evidence of the efficacy of an enzyme combination preparation using the method of artificial hematomas in combination with a pressure meter: A placebo controlled, randomized, prospective, double blind study. Kleine M.W. Allergist / Phlebotomist / Sports Medicine, Egenhofenstrasse 18, D-82152 Planegg, Germany. Journal of Clinical Research 1998, Vol.1, pp. 87-102

100 athletes in a placebo controlled,

double blind, randomized study were

divided into two groups: all conditions

standardized.

- Hematomas were created in all athletes‘

- 50 given oral proteolytic enzymes: 50

given placebo.

• Karate Study/ double blind randomized • Half received oral enzymes 3

times/day for two days before fighting.

• Half received the 'sugar pills' [placebo]

• Placebo group twice as long to 'heal' D. Lopez, MD et. al. In Enzymes Fountain of Life. [page 201]

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Enzyme Placebo

Healing Time

Healing

16 Days

7 Days

• Disease may be made worse when whole proteins from foods “leak” into the blood and cause immune reactions.

• Digestive enzymes are said to help reduce this so- called “leaky gut problem”.

• “Assimilation / Elimination”

Special Note on protein

digestion:

• Summary of several double blind studies on oral enzymes vs. an NSAID

• Studies involved over 400 people with osteoarthritis. • Oral enzymes were as good as,

if not better, than the NSAIDS • Fewer side effects

Clinical Rheumatology Volume 23, Number 5, 410-415, DOI: 10.1007/s10067-004-0902-y Oral enzyme combination versus diclofenac in the treatment of osteoarthritis of the knee – a double-blind prospective randomized study Naseer M. Akhtar, Rizwan Naseer, Abid Z. Farooqi, Wajahat Aziz and Mussadeq Nazir Efficacy and tolerance of an oral enzyme combination in painful osteoarthritis of the hip. A double-blind, randomised study comparing oral enzymes with non-steroidal anti- inflammatory drugs. .Klein G, Kullich W, Schnitker J, Schwann H. : Clin Exp heumatol. 2006 Jan-Feb;24(1):25-30. Rehabilitation Centre for Cardiovascular and Rheumatic Diseases, Germany.

• Bromelain is a group of protein–digesting enzymes.

• It breaks down fibrin—”a key component of body” inflammatory response.

• It appears to inhibit the natural formation of prostaglandins that trigger the natural inflammatory response.

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MYOMEND™

SUPPORT FOR MUSCLE, TISSUE & JOINT FUNCTION • Bromelain, Papain, Protease Thera-blend™

• Assists body’s natural recovery from overexertion and minor injuries

• May promote optimal circulation • Support immune system during normal

inflammatory response • Beneficial for joint health

• Rutin – A flavonoid (plant pigment) that has been known to strengthen blood vessels - used in combination with bromelain

• Serrapeptase • Assists body’s natural tissue repair process to

calm joint discomfort • Maintains balanced secretion of interstitial fluid

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NATTOKINASE PLUS™

CARDIOVASCULAR & CIRCULATORY HEALTH • Nattokinase containing NSK-SD®

• Promotes healthy circulation / blood pressure • Support body’s natural ability to breakdown Fibrin /

Blood clots • Assists with proper blood viscosity

• Lipase Therablend – Supports fat metabolism • Bromelain – Exerts fibrinolytic activity. Research suggests

it supports thrombophlebitis, as it decreases aggregation of blood platelets, has a cardio-protective effect, and reduces thrombus formation.

• Amylase, Protease Therablend, Cellulase Therablend, and Glucoamylase for synergistic enzyme activity.

•Provides: • Cardiovascular support - improved circulation, tissue

repair, and fibrinolytic activity • Improved lipid breakdown • Cardio-protective effect

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No other cell in the body has the natural ability to generate new cell types!!

•Adult Stem Cells divide and differentiate new types of cells •Stem Cells serve as an internal repair system dividing essentially without limit to replenish where needed throughout our lifetimes

http://stemcells.nih.gov/info/basics/

Adult Stem Cell Counts Decrease with Age

DO what you can to

support yours!

Stem Cells What gets us better

- Surgery Stem cells that repair

- Basic building block cells of life

- Blood stem cells “workers”

- Hematopoietic Stem Cells - “Plasticity” convert from one type of cell to another

- More in circulation attraction to injury

- More cells you have quicker you repair and heal from injury

“By nourishing your body’s own adult stem cells, we help the body’s natural ability to repair itself.”

- Cindy Sanberg Ph.D. Neurobiology. USF

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STEM XCELL PRO™

SUPPORTS HEALTH AND FUNCTION OF YOUR STEM CELLS • NT-020™

• Developed and researched by a leading university in the United States.

• Shown to promote growth and health of stem cells. • Shown to protect stem cells and promote improved

function in older stem cells. • Promotes the health, proliferation and maintenance

of neurons for cognitive health. • Blueberry extract, vitamin D3, green tea & carnosine.

• Botanical Enhance Enzymes – Comprised of carbohydrase enzymes to assist with optimal delivery and absorption of formula ingredients.

• Defenze Antioxidant Blend ™ – Helps maintain the immune system and scavenge free radicals.

Synergy of NT-020

Primary neuronal cells were grown in culture and exposed to an oxidative insult (H2O2).

Lactate dehydrogenase (LDH) assay was used.

Results: ~70-80% of the cells in the control groups died (30-20% survival). However, in the presence of NT-020 cell death

was 35% (65% survival!).

(NT-020) Antioxidant Properties

Shytle RD, Ehrhart J, Tan J, Vila J, Cole M, Sanberg CD, Sanberg PR, Bickford PC (2007) Oxidative stress of neural, hematopoietic, and stem cells: protection by natural compounds. Rejuvenation Res 10:173-178.

Bone marrow stem cells grown in culture, and exposed to an oxidative insult (H2O2).

Lactate dehydrogenase (LDH) assay was used.

Results: The low dose showed a 20% decrease in cell death; high dose showed a greater than 40% decrease in cell death; compared to control.

(NT-020) Antioxidant Properties

Shytle RD, Ehrhart J, Tan J, Vila J, Cole M, Sanberg CD, Sanberg PR, Bickford PC (2007) Oxidative stress of neural, hematopoietic, and stem cells: protection by natural compounds. Rejuvenation Res 10:173-178.

High dose = 2 caps of Stem XCell

(13.5mg/kg)

(13.5mg/kg)

(135mg/kg) N = 5 each group

We are dedicated to providing

exceptional enzyme-focused supplements

at the most therapeutic levels available

in the natural foods industry.

It is our commitment to provide

unprecedented education & research

that propels individuals

on the path to vibrant health.

ENZYME SCIENCE founded by Enzymedica with the vision to

build the most complete line of enzyme based supplements for

medical professionals.