epidemiology of hiv and access to prevention services, tanzania joint biennial hiv national response...

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Epidemiology of HIV and Access to Prevention services, Tanzania Joint Biennial HIV National Response Review Stakeholders meeting. November, 2014 Blue Pearl Hotel (David Sando, Sam Sumba, Geoffrey Somi and Raphael Kalinga) JBSNR 11-13, Nov 14. Blue Pearl Hotel 1

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Epidemiology of HIV and Access to Prevention services,

Tanzania

Joint Biennial HIV National Response Review Stakeholders meeting.

November, 2014Blue Pearl Hotel

(David Sando, Sam Sumba, Geoffrey Somi and Raphael Kalinga)

JBSNR 11-13, Nov 14. Blue Pearl Hotel1

Outline

• Trends and distribution of HIV

incidence and prevalence

• Risk factors and access to Preventions

service

• Recommendation for Joint annual review

JBSNR 11-13, Nov 14. Blue Pearl Hotel

2

HIV incidence and MTCT rates

JBSNR 11-13, Nov 14. Blue Pearl Hotel

3

JBSNR 11-13, Nov 14. Blue Pearl Hotel

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JBSNR 11-13, Nov 14. Blue Pearl Hotel

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JBSNR 11-13, Nov 14. Blue Pearl Hotel

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JBSNR 11-13, Nov 14. Blue Pearl Hotel

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JBSNR 11-13, Nov 14. Blue Pearl Hotel

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JBSNR 11-13, Nov 14. Blue Pearl Hotel

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JBSNR 11-13, Nov 14. Blue Pearl Hotel

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Outline

• Trends and distribution of HIV incidence

and prevalence

• Risk factors and access to Preventions

service

• Recommendation for Joint annual review

JBSNR 11-13, Nov 14. Blue Pearl Hotel

11

Effectiveness (%)-60 -20 0 20 40 60 80 100

Effect size (95%CI)

MTN 003 - Daily microbicide for women 15% (-21; 40)

CAPRISA 004 - Coital microbicide for women

31% (1; 51)

iPrEX - Daily PrEP for MSM 44% (15; 63)

TDF2 - Daily PrEP for heterosexual men and women 62% (22; 84)

HPTN 052 - ART for prevention 96% (73; 99)

PartnersPrEP - Daily PrEP for discordant couples 73% (49; 85)

FEM-PrEP - Daily oral PrEP for women 6% (-52; 41)

Sexu

al tr

ansm

issi

on

prev

entio

nPr

even

tion

in ID

Us

Bangkok Tenofovir Study - Daily oral PrEP for IDUs 49% (10; 72)

RV144 - HIV vaccine

39% (6; 60)

Mwanza - STD treatment 42% (21; 58)

Medical male circumcision 54% (38; 66)

Source: adapted from Abdool Karim SS. Lancet 2013

Clinical trial evidence for preventing sex/IDU HIV transmission-July 2013

JBSNR 11-13, Nov 14. Blue Pearl Hotel

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Note: PMTCT, Screening transfusions, Harm reduction, Universal precautions, etc. have not been included – this is on sexual transmission

Behavioural Interventio

n- Abstinence

- Be Faithful

HIV Counselling and TestingCoates T, Lancet 2000

Sweat M, Lancet 2011

Male Condoms

Female Condoms

Treatment of STIs

Grosskurth H, Lancet 2000

Male circumcisi

onAuvert B, PloS Med 2005 Gray R, Lancet 2007Bailey R, Lancet 2007

Treatment for prevention

Cohen M, NEJM, 2011Donnell D, Lancet 2010Tanser, Science 2013

Microbicides

for womenAbdool Karim Q, Science 2010

Grant R, NEJM 2010 (MSM)Baeten J , NEJM 2012 (Couples)Paxton L, NEJM 2012 (Heterosexuals)Choopanya K, Lancet 2013 (IDU)

Oral pre-exposure

prophylaxis

Post Exposure prophylaxis

(PEP)Scheckter M, 2002

ARVprophylaxis

HIVPREVENTION

JBSNR 11-13, Nov 14. Blue Pearl Hotel

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HIV Counseling and Testing

JBSNR 11-13, Nov 14. Blue Pearl Hotel

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Condom use and HIV

JBSNR 11-13, Nov 14. Blue Pearl Hotel

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VMMC status and targets

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JBSNR 11-13, Nov 14. Blue Pearl Hotel

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Access to HEID services, 2013

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Education attainment and HIV

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Age at sexual debut,1999-2012

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Multiple sexual partners in Tanzania

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Outline

• Trends and distribution of HIV incidence

and prevalence

• Risk factors and access to Preventions

service

• Recommendation for Joint annual

review

JBSNR 11-13, Nov 14. Blue Pearl Hotel

25

New infections by mode of transmission

JBSNR 11-13, Nov 14. Blue Pearl Hotel

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JBSNR 11-13, Nov 14. Blue Pearl Hotel

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