epidemiology of wolff- parkinson-white syndrome in ... · pdf file a retrospective study done...

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  • Epidemiology of Wolff- Parkinson-

    White Syndrome in Singapore

    ---- A Preliminary result

    Hossain SM, Bai Rong, Ching Chi

    Keong, Jack Tan, Kuik Hwee Bing,

    Ruth Kam, Teo Wee Siong

  • Objective

    To find out the age, sex and racial

    distributions of WPW syndrome

    among the multi-ethnic

    Singapore population.

  • Clinical significance of WPW

    syndrome study

    Associated with high frequency of

    arrhythmias.

     It shows bizarre and misleading

    electrocardiographic pattern.

    Can be cured by catheter ablation.

  • 12 lead ECG showing different WPW

    pathway

  • Manifest WPW

  • Methods

     A retrospective study done in all WPW syndrome

    patients admitted in NHC for catheter ablation from

    Oct ’1991 to Dec’03.

     Statistical analysis by chi-square and cross

    tabulation methods.

     Accessory pathway is determined by

    • History and physical examination

    • Analysis of surface 12 lead ECG

    • Intracardiac mapping by EPS

  • Picture of normal conductive

    system and wpw PATHWAY

  • Cinefilms to show intracardiac

    catheters

  • Result

    Male

    N=462

    Female

    N=289

    Total

    N=751

    M:F

    1.6:1

    Age 37±14 41±15 38±15

  • Bar chart showing the age

    distributions in Single AP

    AGE_GRP

    70-7960-6950-5940-4930-3920-2910-19

    P e

    rc e

    n t

    30

    28

    26

    24

    22

    20

    18

    16

    14

    12

    10

    8

    6

    4

    2 0

  • Pie chart showing the percentage of the

    each site in Single Accessory Pathway

    3.5%

    12.3%

    3.0%

    12.9%

    68.2%

    Others

    Posteroseptal

    Anteroseptal

    Right free wall

    Left free wall

  • Result - Racial distribution in

    single pathway

    Chinese Malay Indian Others p-value

    Single pathway

    1) LFW

    2) RFW

    3) Anteroseptal

    4) Posteroseptal

    5) Others

    422

    79

    21

    73

    21

    40

    4

    0

    10

    3

    11

    3

    0

    2

    0

    8

    5

    0

    2

    1

    >0.05

    X2 5.28 -5.64 -9.92 1.59

    P-value

  • Gender distribution in single

    pathway

    Male Female P-value

    LFW 297 184

    RFW 47 44

    Anteroseptal 15 6

    Posteroseptal 64 23

    Others 9 16

  • Conclusion

    Male suffers more from WPW syndrome .

     Highest incidence observed in 3rd and 4th

    decade.

     In Singapore LFW also topped the list

    among the WPW syndrome pathways.

  • Thank you!

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